Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Flexible manufacturing OEM & ODM Thailand

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Graphene sheet OEM supplier factory Taiwan

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.China orthopedic insole OEM manufacturer

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Breathable insole ODM development Taiwan

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Taiwan sustainable material ODM production base

University of Geneva researchers have transformed chicken scales into feathers by temporarily modifying the Sonic hedgehog (Shh) gene expression, revealing that significant evolutionary transitions can occur without major changes in the genome. This research sheds light on the mechanisms responsible for the wide diversity of animal forms. Credit: © UNIGE / Cooper & Milinkovitch A UNIGE team shows how specifically modifying gene expression causes feathers to replace scales in the chicken. Scales, spines, feathers and hair are examples of vertebrate skin appendages, which constitute a remarkably diverse group of micro-organs. Despite their natural multitude of forms, these appendages share early developmental processes at the embryonic stage. Two researchers from the University of Geneva (UNIGE) have discovered how to permanently transform the scales that normally cover the feet of chickens into feathers, by specifically modifying the expression of certain genes. These results, published in the journal Science Advances, open new perspectives for studying mechanisms that have enabled radical evolutionary transitions in form among species. The skin of terrestrial vertebrates is adorned with diverse keratinized appendages, such as hair, feathers, and scales. Despite the diversity of forms within and among species, the embryonic development of skin appendages typically begins in a very similar way. Indeed, all of these structures develop from cells that produce a localized thickening on the skin surface and express particular genes. One of these genes, called Sonic hedgehog (Shh), controls a signaling pathway — a communication system that allows the transmission of messages within and between cells. Shh signaling is involved in the development of diverse structures, including the neural tube, limb buds, and skin appendages. A Common Ancestor The laboratory of Michel Milinkovitch, professor in the Department of Genetics and Evolution at the Faculty of Science of the UNIGE, is interested in the physical and biological processes that generate the diversity of skin appendages in vertebrates. In particular, his group has previously demonstrated that hair, feathers, and scales are homologous structures inherited from a reptilian common ancestor. A transient change in expression of one gene (Shh) can produce a cascade of developmental events leading to the formation of feathers instead of scales. Credit: © UNIGE / Cooper & Milinkovitch Feathers of the chicken embryo are used by scientists as a model system to understand skin appendage development. While it is known that certain breeds of chickens, such as the ‘Brahma’ and ‘Sablepoot’ varieties, exhibit feathered legs and dorsal foot surfaces, the genetic determinism of this trait is not fully understood. A Transient Modification for a Permanent Change As the signaling pathways responsible for this transformation have not been fully determined, Michel Milinkovitch’s group investigated the potential role of the Shh pathway. “We used the classic technique of ‘egg candling’, in which a powerful torch illuminates blood vessels on the inside of the eggshell. This allowed us to precisely treat chicken embryos with a molecule that specifically activates the Shh pathway, injected directly into the bloodstream,’’ explains Rory Cooper, a post-doctoral researcher in Michel Milinkovitch’s laboratory and co-author of the study. The two scientists observed that this single stage-specific treatment is sufficient to trigger the formation of abundant juvenile down-type feathers, in areas that would normally be covered with scales. Remarkably, these experimentally-induced feathers are comparable to those covering the rest of the body, as they are regenerative and are subsequently and autonomously replaced by adult feathers. After comparison with embryos injected with a ‘control’ solution (without the active molecule), RNA sequencing analysis showed that the Shh pathway is both immediately and persistently activated following injection of the molecule. This confirms that activation of the Shh pathway underlies the conversion of scales into feathers. ‘‘Our results indicate that an evolutionary leap — from scales to feathers — does not require large changes in genome composition or expression. Instead, a transient change in expression of one gene, Shh, can produce a cascade of developmental events leading to the formation of feathers instead of scales,’’ says Michel Milinkovitch. This research, initially focused on the study of the development of scales and feathers, therefore has important implications for understanding the evolutionary mechanisms generating the enormous diversity of animal forms observed in nature. Reference: “Transient agonism of the sonic hedgehog pathway triggers a permanent transition of skin appendage fate in the chicken embryo” by Rory L. Cooper and Michel C. Milinkovitch, 17 May 2023, Science Advances. DOI: 10.1126/sciadv.adg9619

Indian rhinoceros (Rhinoceros unicornis). Credit: Olivier Bacquet A study reveals major differences between the Sundaic and Indian rhinoceroses, leading scientists to propose a new classification for the Sundaic species as Eurhinoceros sondaicus. A new study has identified significant differences in the appearance and behavior of the two one-horned Asiatic rhinoceros species, challenging traditional classifications and prompting a reconsideration of their taxonomic status. Led by zoologist Francesco Nardelli and paleontologist Kurt Heißig, the research highlights how millions of years of evolutionary pressures have driven distinct adaptations in the Indian rhinoceros (Rhinoceros unicornis) and the Sundaic rhinoceros (Rhinoceros sondaicus). The critically endangered Sundaic rhinoceros has a slender skull, a broader lower back of the head, and a shorter nose and teeth suited for browsing leaves. In contrast, the Indian rhinoceros has a more robust skull and taller teeth adapted for grazing on grasses. Morphological and Behavioral Differences “Adaptations of large terrestrial mammals to various environments are linked to the diversity of food items they can consume, which is reflected in the variation of their dental and cranial morphologies,” the researchers write in their paper, published in the journal ZooKeys. “In rhinoceroses, these adaptations are identified in their teeth structure and head posture.” Sundaic rhinoceros (Eurhinoceros sondaicus). Credit: Toby Nowlan The Sundaic rhinoceros, now confined to Java’s Ujung Kulon peninsula, is a browsing species with uniquely polygonal-patterned skin and, unlike any other living rhinoceros, hornless females. In contrast, the Indian rhinoceros is a grazer of riverine grasslands in northern India and Nepal. With deep skin folds and a heavier build, the Indian rhinoceros is considerably larger than its Sundaic relative. It is superseded in size only by the elephant and the white rhinoceros, with males weighing more than 2,000 kg and females reaching 1,600 kg. Fossil Evidence and Evolutionary History Fossil evidence confirms that these differences evolved independently over a long period of time. The authors maintain that they represent fundamental anatomical and ecological distinctions and reflect deep evolutionary adaptations. The behavior of the two species also differs significantly, with the Sundaic rhinoceros being solitary wanderers and the Indian rhinoceros forming temporary crashes. “Both species possess unique adaptations for survival, emphasizing the importance of understanding their systematics for effective conservation,” the researchers write in their paper. Based on these findings, the scientists propose a more precise scientific name for the Sundaic rhino: Eurhinoceros sondaicus. “Recognizing Eurhinoceros sondaicus as a distinct genus provides a more accurate reflection of its evolutionary history and ecological specialization,” they assert. “This refined classification not only enhances our understanding of rhinoceros evolution but also provides a clearer framework for conservation planning, helping to tailor strategies for the protection of these critically endangered animals.” Reference: “A taxonomic review of the genus Rhinoceros with emphasis on the distinction of Eurhinoceros (Perissodactyla, Rhinocerotidae)” by Francesco Nardelli and Kurt Heißig, 6 March 2025, ZooKeys. DOI: 10.3897/zookeys.1230.127858

Researchers at The University of Texas have discovered that bacteria, specifically E. coli, use iron levels to store and recall information about behaviors like swarming and forming biofilms. This ability, akin to a form of memory, could lead to new methods of combating bacterial infections and antibiotic resistance. Scientists have discovered that bacteria can form memory-like mechanisms, informing strategies that lead to dangerous infections in humans. These strategies include antibiotic resistance and the formation of bacterial swarms, where millions of bacteria congregate on a single surface. This discovery has significant implications for preventing and treating bacterial infections, particularly those involving antibiotic-resistant strains. The process involves a common chemical element that bacterial cells utilize to create and transmit these “memories” to subsequent generations. Discovery by University of Texas Researchers Researchers at The University of Texas at Austin found that E. coli bacteria use iron levels as a way to store information about different behaviors that can then be activated in response to certain stimuli. The findings are published in the Proceedings of the National Academy of Sciences. Scientists had previously observed that bacteria that had a prior experience of swarming (moving on a surface as a collective using flagella) improve subsequent swarming performance.  The UT-led research team set out to learn why. Bacterial swarm on a laboratory plate. Credit: The University of Texas at Austin Understanding Bacterial “Memories” Bacteria don’t have neurons, synapses, or nervous systems, so any memories are not like the ones of blowing out candles at a childhood birthday party. They are more like information stored on a computer. “Bacteria don’t have brains, but they can gather information from their environment, and if they have encountered that environment frequently, they can store that information and quickly access it later for their benefit,” said Souvik Bhattacharyya, the lead author and a provost early career fellow in the Department of Molecular Biosciences at UT. Iron’s Role in Bacterial Behavior It all comes back to iron, one of the most abundant elements on Earth. Singular and free-floating bacteria have varying levels of iron. Scientists observed that bacterial cells with lower levels of iron were better swarmers. In contrast, bacteria that formed biofilms, dense, sticky mats of bacteria on solid surfaces, had high levels of iron in their cells. Bacteria with antibiotic tolerance also had balanced levels of iron. These iron memories persist for at least four generations and disappear by the seventh generation. “Before there was oxygen in the Earth’s atmosphere, early cellular life was utilizing iron for a lot of cellular processes. Iron is not only critical in the origin of life on Earth but also in the evolution of life,” Bhattacharyya said. “It makes sense that cells would utilize it in this way.” Video of bacterial swarm under a microscope. Credit: The University of Texas at Austin Researchers theorize that when iron levels are low, bacterial memories are triggered to form a fast-moving migratory swarm to seek out iron in the environment. When iron levels are high, memories indicate this environment is a good place to stick around and form a biofilm. “Iron levels are definitely a target for therapeutics because iron is an important factor in virulence,” Bhattacharyya said. “Ultimately, the more we know about bacterial behavior, the easier it is to combat them.” Reference: “A heritable iron memory enables decision-making in Escherichia coli” by Souvik Bhattacharyya, Nabin Bhattarai, Dylan M. Pfannenstiel, Brady Wilkins, Abhyudai Singh and Rasika M. Harshey, 21 November 2023, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2309082120 The research was funded by the National Institutes of Health. Rasika Harshey, a professor of molecular biosciences and Mary M. Betzner Morrow Centennial Chair in Microbiology, is the senior corresponding author on the paper. Nabin Bhattarai, Dylan M. Pfannenstiel and Brady Wilkins, along with Abhyudai Singh of University of Delaware, also contributed to the research.

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