Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Taiwan flexible graphene product manufacturing

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Private label insole and pillow OEM Taiwan

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.High-performance graphene insole OEM Vietnam

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Vietnam insole ODM service provider

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Indonesia OEM/ODM hybrid insole services

Figure 3: Florida spot keratopathy (FSK) in dogs and cats with concurrent eye disease. (A) A 9-year-old mixed breed dog diagnosed with subconjunctival hemorrhage, mild uveitis, and multifocal, coalescing FSK lesions. (B) A 6-year-old Cavalier King Charles Spaniel with multifocal FSK lesions post cataract surgery. (C) A 10-year-old DSH cat post debulking and photodynamic therapy due to lower eyelid squamous cell carcinoma, with multifocal FSK lesions. (D) A 14-year-old DSH cat diagnosed with anterior lens luxation, an axial descemetocele and multifocal coalescing FSK lesions. Credit: Oren Pe’er A new study identifies Florida spot keratopathy (FSK) as a stable, benign eye condition in pets and suggests a possible link to little fire ant exposure. Analyzing 100 cases, it also highlights previously unrecognized signs of eye irritation. A recent study from the Koret School of Veterinary Medicine at Hebrew University provides new insights into Florida spot keratopathy (FSK), an eye condition affecting both dogs and cats. Led by Dr. Oren Pe’er and published in Veterinary Ophthalmology, the research examined 100 cases diagnosed between 2021 and 2024. FSK is marked by the appearance of round, white spots on the cornea, the transparent front part of the eye. These spots do not take up fluorescein dye, a diagnostic tool used to detect corneal damage. While the lesions typically remain stable over time, they may cause temporary irritation in some cases. Figure 2: Florida spot keratopathy in four cats. (A) A 10-year-old DSH with four coalescing, paracentral lesions. (B) A 2.5-year-old DSH with four coalescing, ventral lesions. (C) A 5-year-old DSH with multifocal coalescing lesions. (D) A 10-year-old DSH with multifocal lesions. Credit: Oren Pe’er The study included 84 dogs and 16 cats, with the average age of affected dogs being 6.5 years and cats averaging 5.9 years. Most cases involved only one eye, although more than half of the animals had multiple spots in the affected eye. What Are the Effects of FSK?  The spots varied in size, from tiny pinpoint lesions to larger spots measuring up to 7.6 mm in dogs and 5 mm in cats. In dogs, the spots were typically centered in the eye, while in cats, they appeared more scattered across the cornea. Only 4% of dogs and 6% of cats showed signs of the condition worsening over time. Additionally, about 18% of dogs and 12.5% of cats exhibited signs of eye irritation, such as excessive rubbing or blinking. Figure 1: Florida spot keratopathy in four dogs. (A) A 9-year-old mixed breed with five paracentral lesions. (B) A 7-year-old Labrador retriever with one dorsal lesion. (C) An 8-year-old mixed breed with multifocal, coalescing lesions. (D) A 12-year-old mixed breed with multifocal coalescing lesions. Credit: Oren Pe’er Could Fire Ants Be a Factor? An interesting finding from the study is that owners of 21% of affected dogs and 38% of affected cats reported seeing little fire ants (LFA) near their homes. While some prior studies have suggested a potential link between LFA exposure and FSK, no scientific proof has yet been established. “FSK is an eye condition that pet owners and veterinarians should be aware of, but fortunately, it rarely leads to serious complications,” said Dr. Pe’er. “In most cases, the condition remains stable and does not significantly impact a pet’s vision or overall well-being.” While Florida spot keratopathy (FSK) is relatively benign, the study is important because it raises awareness of a condition that veterinarians and pet owners may not be familiar with, ensuring that it is correctly diagnosed and managed. Recognizing FSK can help prevent unnecessary treatments or anxiety for pet owners, while also prompting further research into potential environmental factors, such as fire ants, that may influence its development. Understanding the condition better can improve care and provide valuable insights into pet health and well-being. This research offers valuable insights for veterinarians to recognize and diagnose FSK, ensuring that affected pets receive the best possible care. However, further studies are needed to explore potential environmental factors, including the possible role of little fire ants, in the development of the condition. Reference: “Clinical manifestations of Florida spot keratopathy in dogs and cats: One hundred cases (2021–2024)” by O. Pe’er, K. W. Handel, D. Arad, L. Sebbag and R. Ofri, 25 December 2024, Veterinary Ophthalmology. DOI: 10.1111/vop.13311

“Yellow cells” of the symbiotic algae, Philozoon collosum, isolated from the soft coral, Capnella gaboensis, collected off the east coast of southern Australia. Credit: Matthew R. Nitschke In the late 1800s, scientists were stumped by the “yellow cells” they were observing within the tissues of certain temperate marine animals, including sea anemones, corals, and jellyfish. Were these cells part of the animal or separate organisms? If separate, were they parasites, or did they confer a benefit to the host? Biologist Sir Patrick Geddes of Edinburgh University, in a paper published in the journal Nature in 1882, proffered that not only were these cells distinct entities, but they were also beneficial to the animals in which they lived. He assigned them to a new genus, Philozoon — from the Greek phileo, meaning ‘to love as a friend,’ and zoon, meaning ‘animal’ — and then promptly changed his career direction to pioneer professions in urban planning and design. Over time, Geddes’s scientific contributions were largely forgotten, and the Philozoon genus name was never used. Now, more than a century after Geddes’s paper was published, an international team of scientists has revisited these “yellow cells,” which, after Geddes, had been determined to be photosynthetic algae in the family Symbiodiniaceae. The jellyfish, Cotylorhiza tuberculata, from Naples, Italy hosts the symbiotic algae Philozoon medusarum. Credit: Marco Cannavacciuolo In a study published in the June 28 issue of the European Journal of Phycology, the team resurrected the genus Philozoon by using modern technologies to thoroughly characterize two of the species of algae that Geddes had investigated, along with six new related ones. “Patrick Geddes was ahead of his time in recognizing the ecological significance of the ‘yellow cells’ found in some animals were actually distinct entities — micro-algal symbionts — existing inside the animal’s tissues and creating a photosynthetic animal. That was a major revelation! In fact, we now know that microorganisms live in partnership with all multicellular organisms; for example, the bacteria that comprise our human gut microbiomes are essential for our overall health,” said Todd LaJeunesse, professor of biology, Penn State, and lead author of the paper. “By emending and reviving the Philozoon genus, we are honoring the work of this natural historian. Portrait of Sir Patrick Geddes (c. 1888) at the age of 34, several years after publishing observations from his experiments on animals containing chlorophyll. Credit: libraryblogs.is.ed.ac.uk LaJeunesse and his colleagues used genetic information; outward physical, or morphological, characteristics; ecological traits; and geographic distributions to define the diversity found within the newly recognized Philozoon genus. They obtained animal samples — including from soft and stony corals, jellyfish, and sea anemones — from locations all over the world. They also obtained samples from Italy where Geddes first conducted his original research. “Because our team comprises scientists from seven countries, we were able to collect all of these samples, and some during the global pandemic,” said LaJeunesse. “This study highlights how the spirit of scientific discovery brings people together, even in times of hardship.” “The fact that these algae exist in animals from the Mediterranean Sea to New Zealand to Chile reminds us how widespread these symbioses are on Earth,” said LaJeunesse. “Also, since most of the algae in the family Symbiodiniaceae have been thought to be mostly tropical where they are critical to the formation of coral reefs, finding and describing these new species in cold waters highlights the capacity of these symbioses to evolve and live under a broad range of environmental conditions. Life finds a way to persist and proliferate.” The team documented that at their northernmost and southernmost latitudinal extremes, Philozoon experience water temperatures that may reach winter lows of nearly 40 degrees F and summer highs of close to 90 F. “The abilities of these Philozoons to withstand a wide range of temperatures is likely due to their diversification during the cooler periods of the late Pliocene and most recent Pleistocene epochs,” said LaJeunesse. “This adaptation to a range of temperatures could protect them and the animals with which they associate from some of the effects of climate change, at least in the near term. Similarly, adaptation to high latitude environments may condition Philozoon species to tolerate future increases in atmospheric carbon dioxide, which could also help make them resilient to some of the effects of ocean acidification.” He added that careful identification and categorization of these symbiotic algae is essential to understanding the biology and evolution of marine animals that rely on these organisms for their survival. “The advanced molecular-genetic techniques available to us today have substantially improved our ability to study and understand these microbes,” said Pilar Casado-Amezúa, researcher, HyT Association, Spain. “Our new study lays the groundwork for extensive research on the ecological role of animal-algal mutualisms in temperate marine ecosystems.” LaJeunesse noted that although there were a handful of other scientists during the late 1800s that were investigating these ‘yellow cells’ it was Geddes who unequivocally recognized the full significance of the evidence before him. He explained, “In describing the associations between the cells and the host animals, Geddes called them ‘animal lichens’ and eloquently wrote, ‘Such an association is far more complex than that of the fungus and alga in the lichen, and indeed stands unique in the physiology as the highest development, not of parasitism, but of the reciprocity between the animal and vegetable kingdoms.’ Geddes vigorously contended that these algae were symbiotic in nature. Now, more than a century after their discovery, the true identities of these algae are finally being properly characterized.” Reference: “Revival of Philozoon Geddes for host-specialized dinoflagellates, ‘zooxanthellae’, in animals from coastal temperate zones of northern and southern hemispheres” by Todd C. LaJeunesse, Joerg Wiedenmann, Pilar Casado-Amezúa, Isabella D’Ambra, Kira E. Turnham, Matthew R. Nitschke, Clinton A. Oakley, Stefano Goffredo, Carlos A. Spano, Victor M. Cubillos, Simon K. Davy and David J. Suggett, 28 June 2021, European Journal of Phycology. DOI: 10.1080/09670262.2021.1914863 Other authors on the paper include Joerg Wiedenmann, University of Southampton, United Kingdom; Pilar Casado-Amezúa, Hombre y Territorio Association, Spain; Isabella D’Ambra, Stazione Zoologica Anton Dohrn, Italy; Kira Turnham, Penn State, United States; Matthew Nitschke, University of Technology Sydney, Australia, and Victoria University of Wellington, New Zealand; Clinton Oakley, Victoria University of Wellington, New Zealand; Stefano Goffredo, University of Bologna, Spain, and The Inter-Institute Center for Research on Marine Biodiversity, Resources and Biotechnologies, Italy; Carlos Spano, Ecotecnos S.A., Chile; Victor Cubillos, Universidad Austral de Chile, Chile, and Universidad Austral de Chile, Chile; Simon Davy, Victoria University of Wellington, New Zealand; and David Suggett, University of Technology Sydney, Australia. Funding for this research was provided by the U.S. National Science Foundation, the University of Southampton, the Association of Marine Biology Laboratories Program, the ABBaCo project, PO FEAMP Campania and the Australian Research Council.

Regular cold exposure boosts the body’s natural cell-repair system and strengthens its response to stress, potentially improving health and longevity. Chilling Out Might Just Be the Secret to Healthier Cells New research from the University of Ottawa reveals that repeated cold-water immersion helps train the body to better manage cellular stress. Over just a week of daily exposure to cold water, participants showed improved autophagy—a cellular “recycling” system—and reduced signs of damage. This adaptation could offer protection against disease and aging, hinting that cold acclimation may be more than just a wellness trend. Cold Exposure and Cellular Resilience A new study from the Human and Environmental Physiology Research Unit (HEPRU) at the University of Ottawa has uncovered how cold water acclimation affects key cellular processes in young men. Specifically, the research looked at autophagy – the body’s internal recycling system that maintains cell health – and apoptosis, the controlled removal of damaged cells. The findings suggest that cold exposure may help strengthen the body’s ability to handle stress at the cellular level. The Experiment: Cold Water Immersion Led by postdoctoral fellow Kelli King and Professor Glen Kenny, Director of HEPRU and faculty member at uOttawa’s School of Human Kinetics, the study involved ten healthy young men who took part in cold-water immersion at 14°C (57.2°F) for one hour each day over the course of seven days. Blood samples were collected before and after the immersion period to track cellular changes. “Our findings indicate that repeated cold exposure significantly improves autophagic function, a critical cellular protective mechanism,” says Professor Kenny. “This enhancement allows cells to better manage stress and could have important implications for health and longevity.” “Our findings indicate that repeated cold exposure significantly improves autophagic function, a critical cellular protective mechanism.” Glen Kenny Glen Kenny, Full Professor at uOttawa’s School of Human Kinetics and Director of HEPRU. Credit: University of Ottawa Initial Dysfunction, Followed by Cellular Gains The research revealed that while autophagy was initially dysfunctional after high-intensity cold stress, consistent exposure over a week led to increased autophagic activity and decreased cellular damage signals. “By the end of the acclimation, we noted a marked improvement in the participants’ cellular cold tolerance,” explains King, the study’s first author. “This suggests that cold acclimation may help the body effectively cope with extreme environmental conditions.” Beyond Performance: Health and Longevity The implications of this study extend beyond athletic performance. Cold water immersion has gained popularity for its potential health benefits, and this research provides some scientific backing for its efficacy. The findings suggest that proper autophagic activity could not only extend cellular longevity but also prevent the onset of various diseases. As the use of cold exposure becomes increasingly mainstream, understanding its effects on cellular mechanisms is vital. Professor Kenny emphasizes, “This work underscores the importance of acclimation protocols in enhancing human health, especially in contexts where individuals are exposed to extreme temperatures.” A Tune-Up for Your Cells? “We were amazed to see how quickly the body adapted,” notes King. “Cold exposure might help prevent diseases and potentially even slow down aging at a cellular level. It’s like a tune-up for your body’s microscopic machinery.” These results apply to young males and more research is needed to see if it would also apply to other cohorts. Reference: “The Effect of 7-Day Cold Water Acclimation on Autophagic and Apoptotic Responses in Young Males” by Kelli E. King, James J. McCormick and Glen P. Kenny, 27 November 2024, Advanced Biology. DOI: 10.1002/adbi.202400111

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