Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Indonesia foot care insole ODM expert

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.ODM service for ergonomic pillows Indonesia

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Memory foam pillow OEM factory Indonesia

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.China sustainable material ODM solutions

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.China custom neck pillow ODM

Wild pigs or boars (Sus scorfa) are native to Malaysia and also the entire of Eurasia, and are invasive in all other continents, including Australia and the Americas. Credit: The University of Queensland Nesting wild pigs may help rainforest biodiversity by limiting dominant tree species and allowing rarer ones to thrive. Wild pigs are often maligned as ecosystem destroyers, but a University of Queensland study has found they also cultivate biodiverse rainforests in their native habitats. Dr. Matthew Luskin has been researching the effect of native pigs in Malaysian rainforests and found their nests may be critical to maintaining diverse and balanced tree communities. “We’ve shown that wild pigs can support higher diversity ecosystems and are not just nuisances and pests, thanks to a beneficial effect of their nesting practices,” Dr. Luskin said. The Double-Edged Legacy of Pigs “Prior to giving birth, pigs build birthing nests made up of hundreds of tree seedlings, usually on flat, dry sites in the forest. As they build their nests, the pigs kill many of the dominant seedlings and inadvertently reduce the abundance of locally dominant tree species, but usually not rarer local species, supporting tree diversity.” Dr. Luskin said wild pigs (Sus scrofa) descended from the same species of domestic pigs and both have generally been considered pests by farmers, land managers, and conservationists. “Their negative impacts on natural and cultivated ecosystems have been well documented — ranging from soil disturbances to attacking newborn livestock,” he said. This is the first study to link animals to this key mechanism for maintaining hyper-diverse rainforests. A sow’s birthing nest in Malaysian rainforest. Credit: The University of Queensland The researchers tagged more than 30,000 tree seedlings in a Malaysian rainforest and were able to examine how tree diversity changed in the areas where pigs nested after recovering more than 1800 of those tree tags from inside more than 200 pig birthing nests. Accidental Forest Gardeners “You could consider pigs ‘accidental forest gardeners’ that prune common seedlings and inadvertently maintain diversity,” Dr. Luskin said. “In many regions, there’s a focus on managing overabundant pig populations to limit their negative environmental impacts. But our results suggest there may be some positives to maintaining pigs in the ecosystem.” Dr. Luskin said that as the fieldwork was conducted in Malaysia where pigs are native — the impacts of invasive pigs in Australia may not create similar effects. “We’re currently in the process of designing new research to study the same pig processes here in Queensland,” he said. “And we’ll also be comparing our initial Malaysian results with conditions in a nearby Malaysian forest that is heavily hunted and where many native pigs have been killed. “It’s an intriguing insight, as pigs have become the most widespread large animal on earth, so documenting any new ecological impacts has massive repercussions globally.” Reference: “Wildlife disturbances as a source of conspecific negative density-dependent mortality in tropical trees” by Matthew Scott Luskin, Daniel J. Johnson, Kalan Ickes, Tze Leong Yao and Stuart J. Davies, 3 March 2021, Proceedings of the Royal Society B. DOI: 10.1098/rspb.2021.0001

Genome editing, specifically the CRISPR-Cas9 method, offers a revolutionary solution to Severe Combined Immunodeficiencies (SCIDs) and other genetic disorders. Bar-Ilan University researchers have enhanced this approach with their GE x HDR 2.0 strategy, aiming for precise gene replacement. Bar-Ilan University researchers advance gene therapy for genetic disorders like SCIDs using a refined CRISPR-Cas9 technique, named GE x HDR 2.0. Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer cell function and counts. Left untreated, SCID proves fatal within the first year of life. The conventional treatment for SCID patients involves allogeneic hematopoietic stem cell transplantation (HSCT), but the challenges of finding compatible donors and potential complications like graft-versus-host disease (GVHD) pose significant hurdles in this approach. The Promise of Genome Editing A groundbreaking solution has emerged with the advent of genome editing (GE), particularly using CRISPR-Cas9 technology. This cutting-edge gene therapy research offers hope for many genetic disorders such as SCID. The CRISPR-Cas9 system creates site-specific double-strand breaks in the DNA, allowing for precise gene editing. The repair process can either disrupt a specific gene or correct it, potentially targeting nearly any gene in the genome. This development opens the door to therapeutic interventions for a wide range of genomic diseases. Potential and Challenges of CRISPR-Cas9 HDR One promising genome-editing approach, CRISPR-Cas9 Homology-directed repair (HDR)-mediated GE, offers the potential for precise gene insertion. In certain subtypes of SCID, an alternative to HSCT can involve conventional CRISPR-Cas9 HDR-mediated gene insertion, but it carries inherent risks, especially in cases like RAG2-SCID. RAG2 is nuclease involved in DNA cleavage during lymphocyte development, and CRISPR-Cas9 HDR-mediated gene insertion may lead to uncontrolled RAG2 nuclease activity and harmful structural variations. The GE x HDR 2.0: Find and Replace Strategy In response, researchers from Bar-Ilan University in Israel propose a novel replacement strategy, termed GE x HDR 2.0: Find and Replace. This approach, outlined in a paper published today in Nature Communications, combines CRISPR-Cas9-mediated genome editing with recombinant adeno-associated serotype 6 (rAAV6) DNA donor vectors to precisely replace the RAG2 coding sequence while preserving regulatory elements. This strategy can be applied also to other genes with hot spot regions for disease-causing mutations. Dr. Ayal Hendel, of Bar-Ilan University’s Goodman Faculty of Life Sciences, emphasized, “Our innovation hinges on a crucial insight: to efficiently trigger CRISPR-Cas9 HDR-mediated GE for precise coding sequence replacement, it’s essential to separate the distal homology arm from the cleavage site and align it with the sequence immediately downstream of the segment needing replacement. “In this process, elongating the distal homology arm length in the donor is of paramount importance. By preserving endogenous regulatory elements and intronic sequences, our approach faithfully reproduces natural gene expression levels, thus reducing the associated risks of unregulated gene expression. “This groundbreaking technique, which involves replacing entire coding sequences or exons while retaining critical regulatory elements, brings hope to patients with RAG2-SCID and holds promise for the treatment of various other genetic disorders.” Reference: “CRISPR-Cas9 engineering of the RAG2 locus via complete coding sequence replacement for therapeutic applications” by Daniel Allen, Orli Knop, Bryan Itkowitz, Nechama Kalter, Michael Rosenberg, Ortal Iancu, Katia Beider, Yu Nee Lee, Arnon Nagler, Raz Somech and Ayal Hendel, 27 October 2023, Nature Communications. DOI: 10.1038/s41467-023-42036-5

Gut section with fluorescently labeled bacteria. Credit: Huimin Ye An international team of scientists led by microbiologists Professor Alexander Loy from the University of Vienna and Professor David Schleheck from the University of Konstanz has uncovered new metabolic capabilities of gut bacteria. For the first time, the researchers have analyzed how microbes in the gut process the plant-based, sulfur-containing sugar sulfoquinovose. Sulfoquinovose is a sulfonic acid derivative of glucose and is found in all green vegetables such as spinach and lettuce. Their study discovered that specialized bacteria cooperate in the utilization of the sulfosugar, producing hydrogen sulfide. This gas — known for its rotten egg smell — has disparate effects on human health: at low concentrations, it has an anti-inflammatory effect, while increased amounts of hydrogen sulfide in the intestine, in turn, are associated with diseases such as cancer. The study has been published in the current issue of The ISME Journal. Diet and the gut microbiome With the consumption of a single type of vegetable such as spinach, hundreds of chemical components enter our digestive tract. There, they are further metabolized by the gut microbiome, a unique collection of hundreds of microbial species. The gut microbiome thus plays a major role in determining how nutrition affects our health. “So far, however, the metabolic capabilities of many of these microorganisms in the microbiome are still unknown. That means we don’t know what substances they feed on and how they process them,” explains Buck Hanson, lead author of the study and a microbiologist at the Center for Microbiology and Environmental Systems Science (CMESS) at the University of Vienna. “By exploring the microbial metabolism of the sulfosugar sulfoquinovose in the gut for the first time, we have shed some light into this black box,” he adds. The study thus generates knowledge that is necessary to therapeutically target the interactions between nutrition and the microbiome in the future. Sulfosugars from green plants and algae Sulfoquinovose is a sulfonic acid derivative of glucose and is found as a chemical building block primarily in green vegetables such as spinach, lettuce, and algae. From previous studies by the research group led by microbiologist David Schleheck at the University of Konstanz, it was known that other microorganisms can in principle use the sulfosugar as a nutrient. In their current study, the researchers from the Universities of Konstanz and Vienna used analyses of stool samples to determine how these processes specifically take place in the human intestine. “We have now been able to show that, unlike glucose, for example, which feeds a large number of microorganisms in the gut, sulfoquinovose stimulates the growth of very specific key organisms in the gut microbiome,” says David Schleheck. These key organisms include the bacterium of the species Eubacterium rectale, which is one of the ten most common gut microbes in healthy people. “The E. rectale bacteria ferment sulfoquinovose via a metabolic pathway that we have only recently deciphered, producing, among other things, a sulfur compound, dihydroxypropane sulfonate or DHPS for short, which in turn serves as an energy source for other intestinal bacteria such as Bilophila wadsworthia. Bilophila wadsworthia ultimately produces hydrogen sulfide from DHPS via a metabolic pathway that was also only recently discovered,” explains the microbiologist. A question of dose: hydrogen sulfide in the intestine Hydrogen sulfide is produced in the intestine by our own body cells as well as by specialized microorganisms and has a variety of effects on our body. “This gas is a Janus-faced metabolic product,” explains Alexander Loy, head of the research group at the University of Vienna. “According to current knowledge, it can have a positive but also a negative effect on intestinal health.” A decisive factor, he says, is the dose: In low amounts, hydrogen sulfide can have an anti-inflammatory effect on the intestinal mucosa, among other things. Increased hydrogen sulfide production by gut microbes, on the other hand, is associated with chronic inflammatory diseases and cancer. Until now, mainly sulfate and taurine, which are found in increased amounts in the intestine as a result of a diet rich in meat or fat, were known to be sources of hydrogen sulfide for microorganisms. The discovery that sulfoquinovose from green foods such as spinach and algae also contribute to the production of the gas in the gut therefore comes as a surprise. “We have shown that we can use sulfoquinovose to promote the growth of very specific gut bacteria that are an important component of our gut microbiome. We now also know that these bacteria in turn produce the contradictory hydrogen sulfide from it,” Loy sums up. Further studies by the scientists from Konstanz and Vienna will now clarify whether and how the intake of the plant-based sulfosugar can have a health-promoting effect. “It is also possible that sulfoquinovose could be used as a so-called prebiotic,” adds Schleheck. Prebiotics are food ingredients or additives that are metabolized by specific microorganisms and used to explicitly support the intestinal microbiome. Key facts: Study shows that the sulfosugar sulfoquinovose from green vegetables promotes the growth of important gut bacteria Specialized bacteria cooperate in the utilization of the sulfosugar sulfoquinovose, producing hydrogen sulfide, which has an anti-inflammatory effect in low concentrations, while increased amounts are associated with diseases such as cancer Joint study by the Universities of Konstanz and Vienna involving the research groups led by the microbiologists Professor David Schleheck from the University of Konstanz and Professor Alexander Loy from the University of Vienna References: “Sulfoquinovose is a select nutrient of prominent bacteria and a source of hydrogen sulfide in the human gut” by Buck T. Hanson, K. Dimitri Kits, Jessica Löffler, Anna G. Burrichter, Alexander Fiedler, Karin Denger, Benjamin Frommeyer, Craig W. Herbold, Thomas Rattei, Nicolai Karcher, Nicola Segata, David Schleheck and Alexander Loy, 31 March 2021, The ISME Journal. DOI: 10.1038/s41396-021-00968-0 “Environmental and Intestinal Phylum Firmicutes Bacteria Metabolize the Plant Sugar Sulfoquinovose via a 6-Deoxy-6-sulfofructose Transaldolase Pathway” by Benjamin Frommeyer, Alexander W. Fiedler, Sebastian R. Oehler, Buck T. Hanson, Alexander Loy, Paolo Franchini, Dieter Spiteller and David Schleheck, 28 August 2020, iScience. DOI: 10.1016/j.isci.2020.101510 Funding: The work of Professor Schleheck’s group at the University of Konstanz is funded by the German Research Foundation (DFG)

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