Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Custom graphene foam processing Taiwan

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.ODM service for ergonomic pillows Indonesia

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.High-performance insole OEM factory Taiwan

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.China anti-odor insole OEM service

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Insole ODM factory in Vietnam

A study by the University of Göttingen on Mesotaenium endlicherianum, an alga closely related to land plants, revealed crucial genetic insights. By analyzing the alga’s response to various environmental conditions, researchers uncovered shared genetic mechanisms between algae and land plants, deepening understanding of plant evolution and resilience. A research team from Göttingen University leads an investigation into 10 billion RNA snippets to identify “hub genes.” The majority of the Earth’s land surface is adorned with a diverse array of plants, which constitute the majority of biomass on land. This remarkable diversity spans from delicate mosses to towering trees. This astounding biodiversity came into existence due to a fateful evolutionary event that happened just once: plant terrestrialization. This describes the point where one group of algae, whose modern descendants can still be studied in the lab, evolved into plants and invaded land around the world. An international group of researchers, spearheaded by a team from the University of Göttingen, generated large-scale gene expression data to investigate the molecular networks that operate in one of the closest algal relatives of land plants, a humble single-celled alga called Mesotaenium endlicherianum. Their results were published in Nature Plants. Liquid samples of Mesotaenium endlicherianum in a laboratory flask, which are about to be combined with fresh medium under sterile conditions. Credit: Janine Fürst-Jansen Unveiling Algal Resilience Using a strain of Mesotaenium endlicherianum that has been kept safe in the Algal Culture Collection at Göttingen University (SAG) for over 25 years and the unique experimental set-up there, the researchers exposed Mesotaenium endlicherianum to a continuous range of different light intensities and temperatures. Janine Fürst-Jansen, researcher at the University of Göttingen, states: “Our study began by examining the limits of the alga’s resilience – to both light and temperature. We subjected it to a wide temperature range from 8 °C to 29 °C. We were intrigued when we observed the interplay between a broad temperature and light tolerance based on our in-depth physiological analysis.” Microscope image of one of the closest algal relatives of land plants, a single-celled alga called Mesotaenium endlicherianum (20 micrometers corresponds to 0.02 millimeters). Credit: Tatyana Darienko How the algae respond was not only investigated on a morphological and physiological level, but also by reading the information of about 10 billion RNA snippets. The study used network analysis to investigate the shared behavior of almost 20,000 genes simultaneously. In these shared patterns, “hub genes” that play a central role in coordinating gene expression in response to various environmental signals were identified. This approach not only offered valuable insights into how algal gene expression is regulated in response to different conditions but, combined with evolutionary analyses, how these mechanisms are common to both land plants and their algal relatives. Samples of Mesotaenium endlicherianum that have been kept safe in the Algal Culture Collection at Göttingen University (SAG) for over 25 years. This image shows the unique experimental set-up that allowed the researchers to expose Mesotaenium endlicherianum to a continuous range of different light intensities and temperatures. Credit: Janine Fürst-Jansen Discovering Evolutionary Genetic Mechanisms Professor Jan de Vries, University of Göttingen, says: “What is so unique about the study is that our network analysis can point to entire toolboxes of genetic mechanisms that were not known to operate in these algae. And when we look at these genetic toolboxes, we find that they are shared across more than 600 million years of plant and algal evolution!” As Armin Dadras, PhD student at the University of Göttingen, explains: “Our analysis allows us to identify which genes collaborate in various plants and algae. It’s like discovering which musical notes consistently harmonize in different songs. This insight helps us uncover long-term evolutionary patterns and reveals how certain essential genetic ‘notes’ have remained consistent across a wide range of plant species, much like timeless melodies that resonate across different music genres.” Reference: “Environmental gradients reveal stress hubs pre-dating plant terrestrialization” by Armin Dadras, Janine M. R. Fürst-Jansen, Tatyana Darienko, Denis Krone, Patricia Scholz, Siqi Sun, Cornelia Herrfurth, Tim P. Rieseberg, Iker Irisarri, Rasmus Steinkamp, Maike Hansen, Henrik Buschmann, Oliver Valerius, Gerhard H. Braus, Ute Hoecker, Ivo Feussner, Marek Mutwil, Till Ischebeck, Sophie de Vries, Maike Lorenz and Jan de Vries, 28 August 2023, Nature Plants. DOI: 10.1038/s41477-023-01491-0

One of two new species of the mysterious Urodacus genus of burrowing scorpions – with many more museum specimens still to be described. Credit: B Buzatto (Flinders University) New research has uncovered unexpected characteristics in two newly identified species of burrowing scorpions, including a very strangely shaped ‘tail tip’ and some ‘sexy’ anatomy features. Terrestrial biologists from South Australia’s Flinders University, West Australian universities, and the Museum of WA have taken a closer look at two new species of the mysterious Urodacus genus of burrowing scorpions endemic to Australia – only to find a big difference in their tails compared to other species. Unique Features of Urodacus Scorpions “By also looking at their internal genitalia, rather than only the external morphology, we discovered what we initially thought was one strange species – quite distinctive from other known Urodacus species – was actually two new unusual species,” says Flinders University evolutionary biologist Dr. Bruno Buzatto, lead author of a new article in the Australian Journal of Zoology. “One novel feature of these two new species, Urodacus uncinus and Urodacus lunatus, is that the males have noticeable enlargement in their sting or telson where the venom glands are located. The tip of their ‘tails’ features swollen vesicle and an aculeus that is more strongly curved than other known species of Urodacus.” Dr. Bruno Buzatto is an evolutionary biologist at Flinders University who focuses on behavioral ecology and sexual selection. Credit: Flinders University The new article adds to existing descriptions of 21 already known species of Urodacus scorpions, with experts suggesting a further 100 could still be discovered and examined in future. U. uncinus was named after the hooked shape of its sting (aculeus) and U. lunatus for a moon-shaped structure on its hemispermatophore. “It’s important to study and understand the biodiversity of these burrowing scorpions and list species of conservation significance because a lot haven’t been discovered or properly described yet,” says Dr Buzatto. Mating Behavior and Threats Senior author Dr Erich Volschenk, who is an Australian scorpion taxonomist, says the two new species are a little bit similar to U. similis and U. yaschenkoi in their external morphology but little is yet known about the new species’ behavior, ecology and physiology, and other features such as their venom. “What we did discover is that these two species are quite distinctive in their hemispermatophores, which are structures that occupy the full length of their abdomen and fuse together to produce the spermatophore. This is the first time in Urodacus research that we have used hemispermatophore morphology to diagnose two different species, however, we can still only speculate about how these structures work during mating. After mating, the male scorpions will re-grow hemispermatophores and can mate again within two weeks.” The researchers warn that the pet trade and mining industry could pose threats to burrowing scorpions, which have adapted to live in hot arid ecosystems by burrowing underground. Three of the known Urodacus species are featured in the top 10 most popular invertebrate species in online pet trade, one recent study shows. The trade and keeping of exotic pets such as Australian scorpions has serious implications for biodiversity conservation and biosecurity, the researchers say. Habitat and Venom Characteristics “So far, we only know these two new species have a narrow range in the Pilbara, restricted to creeks and drainage lines, so we need to investigate their habitat requirements a bit more in future research,” says Dr Buzatto. Some species of Urodacus can live up to 20 years in the wild but deep burrowing species are unlikely to live longer than one year in captivity, adds Dr Volschenk. He says the stings of Urodacus burrowing scorpion seem to be more benign to people than the venom of other Australian scorpions classified in the Buthidae family. In general, the venom of Australian scorpions is not considered medically significant and not as dangerous to humans as scorpions on other continents. Reference: “Two new species of burrowing scorpions (Urodacidae: Urodacus) from the Pilbara region of Western Australia with identical external morphology” by Bruno A. Buzatto, Huon L. Clark, Mark S. Harvey and Erich S. Volschenk, 3 November 2023, Australian Journal of Zoology. DOI: 10.1071/ZO23018

A study by Johns Hopkins Medicine reveals a link between lower serotonin levels in the brain and memory issues in people with mild cognitive impairment. This finding, published in the Journal of Alzheimer’s Disease, suggests that targeting serotonin could offer a new approach to treating memory problems and possibly slowing Alzheimer’s disease progression. PET scans of people with mild cognitive impairment detected lower levels of serotonin, the brain chemical associated with positive mood, compared to those without it. Comparing PET scans of more than 90 adults with and without mild cognitive impairment (MCI), Johns Hopkins Medicine researchers say relatively lower levels of the so-called “happiness” chemical, serotonin, in parts of the brain of those with MCI may play a role in memory problems including Alzheimer’s disease. The findings, recently published in the Journal of Alzheimer’s Disease, lend support to growing evidence that measurable changes in the brain happen in people with mild memory problems long before an Alzheimer’s diagnosis, and may offer novel targets for treatments to slow or stop disease progression. Evidence of Brain Changes Preceding Alzheimer’s “The study shows that people with mild cognitive impairment already display loss of the serotonin transporter. This measure that reflects serotonin degeneration is associated with problems with memory, even when we take into account in our statistical model MRI measures of neurodegeneration and PET measures of the amyloid protein that are associated with Alzheimer’s Disease,” says Gwenn Smith, Ph.D., professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine. Understanding Mild Cognitive Impairment MCI describes the diagnostic stage between normal brain function in aging and Alzheimer’s Disease (AD). Symptoms of MCI include frequent forgetfulness of recent events, word finding difficulty, and loss of the sense of smell. Those with MCI may stay in this stage indefinitely, or progress to more severe forms of cognitive deficits, giving urgency to the search for predictive markers, and possible early prevention interventions, investigators say. The investigators cautioned that their study showed a correlation between lower serotonin transporter levels and memory problems in MCI, and was not designed to show causation or the role of serotonin in the progression from MCI to AD. To answer these questions, further research is needed to study over time healthy controls and individuals with MCI to demonstrate the role of serotonin in disease progression. Study Design and Findings For the study, the Hopkins scientists recruited 49 volunteers with MCI, and 45 healthy adults ages 55 and older who underwent an MRI to measure changes in brain structure and two positron emission tomography (PET) scans of their brains at Johns Hopkins between 2009 and 2022. The research team used PET scans to look specifically at the serotonin transporter – a neurotransmitter, or brain chemical long associated with positive mood, appetite and sleep – and to look at the amyloid-beta protein (Aβ) distribution in the brain. Aβ is thought to play a central role in the pathology of AD. Studies in mice done at Johns Hopkins have shown that serotonin degeneration occurs before the development of widespread beta-amyloid deposits in the brain.  Loss of serotonin is often associated with depression, anxiety, and psychological disorders. Researchers found that MCI patients had lower levels of the serotonin transporter, and higher levels of Aβ than healthy controls. The MCI patients had up to 25% lower serotonin transporter levels in cortical and limbic regions than healthy controls. In particular, they report, lower serotonin transporter levels were found in cortical, limbic, and subcortical regions of the brains in those with MCI, areas specifically responsible for executive function, emotion, and memory. “The correlation we observed between lower serotonin transporters and memory problems in MCI is important because we may have identified a brain chemical that we can safely target that may improve cognitive deficits and, potentially, depressive symptoms,” says Smith. “If we can show that serotonin loss over time is directly involved in the transition from MCI to AD, recently developed antidepressant medications may be an effective way to improve memory deficits and depressive symptoms and thus, may be a powerful way forward to slow disease progression.” Future Research Researchers say future studies include longitudinal follow-up of individuals with MCI to compare serotonin degeneration to the increase in and Aβ levels, as well as the increase in levels of the Tau protein that is also associated with AD compared to healthy adults. They are also studying multi-modal antidepressant drugs to treat depression and memory deficits in hopes of mitigating and halting symptoms. Reference: “Serotonin Degeneration and Amyloid-β Deposition in Mild Cognitive Impairment: Relationship to Cognitive Deficits” by Gwenn S Smith, Hiroto Kuwabara, Haijuan Yan, Najlla Nassery, Mark Yoon, Vidya Kamath, Michael Kraut, Neda F Gould, Alena Savonenko, Jennifer M Coughlin, Martin Lodge, Martin G Pomper, Ayon Nandi, Daniel Holt, Robert F Dannals and Jeannie M Leoutsakos, 24 October 2023, Journal of Alzheimer’s Disease. DOI: 10.3233/jad-230570 Other scientists at the Johns Hopkins University School of Medicine and Johns Hopkins Bloomberg School of Public Health who contributed to this research are Jennifer Coughlin, Robert Dannals, Neda Gould, Daniel Holt, Vidya Kamath, Michael Kraut, Hiroto Kuwabara, Jeannie Leoutsakos, Martin Lodge, Ayon Nandi, Najlla Nassery, Martin Pomper, Alena Savonenko, Haijuan Yan and Mark Yoon. This research was partly supported by the National Institutes of Health.

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