Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw

China OEM factory for footwear and bedding

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Vietnam anti-odor insole OEM service

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Indonesia OEM/ODM hybrid insole services

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Breathable insole ODM development Vietnam

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Graphene cushion OEM factory in Indonesia

Recent research led by Julia Notar at Duke University reveals that brittle stars, despite lacking brains, can learn through experience. These marine creatures, related to starfish, use their nerve cords to learn by association, a concept demonstrated in classical conditioning. Brainless brittle stars are capable of learning through experience, as demonstrated in new research. They exhibit classical conditioning by associating darkness with feeding, a significant discovery in understanding learning processes in brainless marine creatures. We humans are fixated on big brains as a proxy for smarts. But headless animals called brittle stars have no brains at all and still manage to learn through experience, new research reveals. Relatives of starfish, brittle stars spend most of their time hiding under rocks and crevices in the ocean or burrowing in the sand. These shy marine creatures have no brain to speak of — just nerve cords running down each of their five wiggly arms, which join to form a nerve ring near their mouth. “There’s no processing center,” said lead author Julia Notar, who did the research as part of her biology Ph.D. in professor Sönke Johnsen’s lab at Duke University. “Each of the nerve cords can act independently,” Notar said. “It’s like instead of a boss, there’s a committee.” In a series of experiments, brittle stars learned that “lights out” was a dinner bell call to come for dinner. Credit: Julia Notar Unraveling Learning in Brainless Marine Creatures In the case of brittle stars, that seems to be enough to learn by association, Notar, Johnsen, and former Duke undergraduate Madeline Go report in the journal Behavioral Ecology and Sociobiology. This type of learning involves associating different stimuli via a process called classical conditioning. A famous example is Pavlov’s dog experiments, which showed that dogs repeatedly fed at the ringing of a bell would eventually start drooling at the mere sound of a bell, even when no food was around. Humans do this all the time. If you hear the “ding” of a smartphone over and over again with each new alert, eventually the sound starts to have a special meaning. Just hearing someone’s phone ping or buzz with the same chime as yours is enough to make you reflexively reach for your own phone in anticipation of the next text, email, or Instagram post. Classical conditioning has been demonstrated in a handful of previous studies in starfish. But most echinoderms — a group of some 7,000 species that includes brittle stars and similarly brainless starfish, sea urchins and sea cucumbers — have not been tested. To find out if brittle stars are capable of learning, the researchers put 16 black brittle stars (Ophiocoma echinata) in individual water tanks and used a video camera to record their behavior. This time-lapse video shows a classical conditioning experiment Duke researchers conducted to see if brittle stars – which don’t have brains – could learn. Every time the lights went dim, the researchers put a pipette with a morsel of shrimp in the animals’ tanks. Over time the animals learned that “lights out” was a dinner bell call to come for dinner. Half the brittle stars were trained by dimming the lights for 30 minutes whenever the animals were fed. Every time the lights went out, the researchers would put a morsel of shrimp — “which they love” — in the tanks, placed just out of reach. The other half got just as much shrimp and also experienced a 30-minute dark period, but never at the same time — the animals were fed under lit conditions. Whether it was light or dark, the animals spent most of their time hiding behind the filters in their tanks; only coming out at mealtime. But only the trained brittle stars learned to associate darkness with food. Early in the 10-month-long experiment, the animals stayed hidden when the lights went out. But over time, the animals made such a connection between the darkness and mealtime that they reacted as if food was on its way and crept out of hiding whenever the lights went out, even before any food was put in the tanks. These brittle stars had learned a new association: lights out meant that food was likely to show up. They didn’t need to smell or taste the shrimp to react. Just sensing the lights go dim was enough to make them come when called for dinner. Discovering Learning and Memory in Echinoderms They still remembered the lesson even after a 13-day ‘break’ without training, i.e., dimming the lights over and over again without feeding them. Notar said the results are “exciting” because “classical conditioning hasn’t really been shown definitively in this group of animals before.” “Knowing that brittle stars can learn means they’re not just robotic scavengers like little Roombas cleaning up the ocean floor,” Notar said. “They’re potentially able to expect and avoid predators or anticipate food because they’re learning about their environment.” As a next step, Notar hopes to start to tease apart how they manage to learn and remember using a nervous system that is so different from our own. “People ask me all the time, ‘how do they do it?’” Notar said. “We don’t know yet. But I hope to have more answers in a few years.” Reference: “Learning without a brain: classical conditioning in the ophiuroid Ophiocoma echinata” by Julia C. Notar, Madeline C. Go and Sönke Johnsen, 21 November 2023, Behavioral Ecology and Sociobiology. DOI: 10.1007/s00265-023-03402-x This work was supported by the U.S. Department of Department of Defense through the National Defense Science & Engineering Graduate Fellowship Program, the Duke Nicholas School Rachel Carson Scholars program and the Duke Biology Department.

Johns Hopkins neuroscientists have pinpointed a mechanism in the brain responsible for a common type of age-related memory loss. As the brain ages, a region in the hippocampus becomes imbalanced, causing forgetfulness. Researchers say understanding this region of the brain and its function may be the key to preventing cognitive decline. Working with rats, neuroscientists at Johns Hopkins University have identified a mechanism in the brain responsible for a common type of age-related memory loss. The work, published on May 202, 2022, in the journal Current Biology, provides new insight on the workings of aging brains and may deepen our understanding of Alzheimer’s disease and similar disorders in humans. “We’re trying to understand normal memory and why a part of the brain called the hippocampus is so critical for normal memory,” said senior author James Knierim, a professor at the university’s Zanvyl Krieger Mind/Brain Institute. “But also with many memory disorders, something is going wrong with this area.” Neuroscientists know that neurons in the hippocampus, located deep in the brain’s temporal lobe, are responsible for a complementary pair of memory functions called pattern separation and pattern completion. These functions occur in a gradient across a tiny region of the hippocampus called CA3. “We’re trying to understand normal memory and why a part of the brain called the hippocampus is so critical for normal memory. But also with many memory disorders, something is going wrong with this area.” James Knierim, Mind/Brain Institute The Imbalance of Memory Functions in Aging When those functions swing out of balance, memory becomes impaired, causing symptoms like forgetfulness or repeating oneself. The Johns Hopkins researchers discovered that as the brain ages, this imbalance may be caused by the CA3 gradient disappearing; the pattern separation function fades away, and the pattern completion function takes over. Neurons responsible for pattern separation are typically more prevalent in the proximal region of the CA3 area, while those responsible for pattern completion are prevalent in the distal region, said lead author Heekyung Lee, an assistant research scientist at the Mind/Brain Institute, With aging, neural activity in the proximal region becomes overactive, and the interplay between the two regions becomes abnormal, creating a dominance in pattern completion. Effects of Imbalanced Memory Functions In normal brains, pattern separation and pattern completion work hand-in-hand to sort and make sense of perceptions and experiences, from the most basic to the highly complex. If you visit a restaurant with your family and a month later you visit the same restaurant with friends, you should be able to recognize that it was the same restaurant, even though some details have changed—this is pattern completion. But you also need to remember which conversation happened when, so you do not confuse the two experiences—this is pattern separation. When pattern separation disappears, pattern completion overpowers the process. With your brain focusing on the common experience of the restaurant to the exclusion of the details of the separate visits, you might remember a conversation about a trip to Italy during one visit, but mistake who was talking. “We all make these mistakes, but they just tend to get worse with aging,” Knierim said. In experiments, the scientists compared young rats with unimpaired memories to older rats with unimpaired memories and older rats with impaired memories. While the older rats with unimpaired memories performed water maze tasks as well as young rats, the neurons in the CA3 regions of their hippocampi were already beginning to favor pattern completion at the expense of pattern separation. Since that physiological finding had not shown up in their behavior, the researchers concluded that something was allowing the rats to compensate for the deficit. Preventing Cognitive Decline That finding is echoed in humans who remain surprisingly sharp into their older years, the researchers say. So pinpointing the memory loss mechanism could lay the groundwork for learning what prevents memory impairment in some humans, and therefore how to prevent or delay cognitive decline in the elderly. “If we can understand better what these compensatory mechanisms are, then maybe we can help prevent cognitive decline with aging,” Knierim said. “Or, if we can’t stop it, maybe we can enhance other parts of the brain to compensate for the losses that are occurring.” Other senior authors of the paper were Michela Gallagher, Krieger-Eisenhower Professor of Psychology and Neuroscience at Johns Hopkins, and Scott Zeger, professor of biostatistics at Johns Hopkins’ Bloomberg School of Public Health. Gallagher’s lab previously demonstrated that the anti-epilepsy drug Levetiracetam improves memory performance by reducing hyperactivity in the hippocampus. So Lee also speculates that this new, more specific information about how memory impairment occurs might allow scientists to better aim such drugs toward the deficits in the future. “It would give us better control of where we could possibly target the deficits that we see,” she said. Reference: “Loss of functional heterogeneity along the CA3 transverse axis in aging” by Heekyung Lee, Zitong Wang, Arjuna Tillekeratne, Nick Lukish, Vyash Puliyadi, Scott Zeger, Michela Gallagher and James J. Knierim, 20 May 2022, Current Biology. DOI: 10.1016/j.cub.2022.04.077 The paper’s other co-authors were Zitong Wang, Arjuna Tillekeratne, Nick Lukish, and Vyash Puliyadi, all of Johns Hopkins.

Venomius tomhardyi pictured next to an illustration of Tom Hardy’s Venom character. Credit: Photo by Rossi et al. Illustration by Zeeshano0 via Pixabay A Distinctive Appearance Leads to an Unusual Name Tom Hardy and his iconic Marvel role, Venom, have inspired the naming of a newly discovered Australian spider. The genus Venomius and its only current species Venomius tomhardyi were described following an expedition to Tasmania. Scientists MSc Giullia Rossi, Dr Pedro Castanheira, and Dr Volker Framenau from Murdoch University (Perth, Australia) partnered with Dr Renner Baptista from the Federal University of Rio de Janeiro (Brazil) to describe the new genus of orb-weaving spiders published in the open access journal Evolutionary Systematics. Tom Hardy portrays Eddie Brock and his alter-ego Venom, an antihero closely associated with Spider-Man, across two Marvel films and gives his name to the sole species of the new genus. The distinctive black spots on the spider’s abdomen reminded the scientists of Venom’s head, inspiring them to select the unusual name. Classification and Unique Behavior of the New Genus The genus belongs to the Araneidae family of spiders that build upright circular webs to capture prey. Despite resembling the related genus Phonognatha as both do not have tubercles on the abdomen, the newly described spiders are distinct in their behavior of creating silk-lined holes in the branches of trees for shelter, as well as their different genitalia. The holotype of the new species was discovered and subsequently preserved at the Queen Victoria Museum and Art Gallery following an expedition to Tasmania, Victoria, South Australia, and Western Australia. Supplementary specimens were also sourced from scientific collections, with the researchers examining approximately 12,000 records in Australian and overseas institutions. Regarding the bigger picture of the study, Dr Pedro Castanheira said: “This is part of a long-term research that aims to document the entire Australian spider fauna, which will be of extreme importance for conservation management plans and the continuation of the decadal plan for taxonomy and biosystematics in Australia and New Zealand.” “It is really important to keep describing new spiders to assess the total biodiversity of these predators in Australia,” added the study’s first author MSc Giullia Rossi. Reference: “Venomius, a new monotypic genus of Australian orb-weaving spiders (Araneae, Araneidae)” by Giullia de F. Rossi, Pedro de S. Castanheira, Renner L. C. Baptista and Volker W. Framenau, 4 September 2023, Evolutionary Systematics. DOI: 10.3897/evolsyst.7.110022

DVDV1551RTWW78V