Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Taiwan ergonomic pillow OEM supplier

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Ergonomic insole ODM support Thailand

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.PU insole OEM production in Thailand

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Taiwan insole OEM manufacturer

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Graphene sheet OEM supplier Thailand

Various rice plants, both control plants and mutants, between three and four weeks after inoculation. Credit: IRD / Laurence Albar The so-called Rice Yellow Mottle Virus (for short: RYMV) is responsible for high crop losses in Africa, particularly among small-scale farmers. A research team from Heinrich Heine University Düsseldorf (HHU) and the French National Research Institute for Sustainable Development (IRD) has now produced rice lines that are resistant to the disease by means of genome editing. The rice varieties, the development of which the team describes in Plant Biotechnology Journal, are a preliminary step toward being able to generate resistant locally adapted elite varieties for small-scale food producers in Africa. RYMV is an RNA virus spread by beetles and direct leaf-to-leaf contact. In Africa, where the majority of producers farm plots of land barely one hectare in size, between ten and one hundred percent of the rice harvests are regularly lost to this virus. This makes it a life-threatening problem for the poorest farmers. Developing Resistant Rice Varieties There is no effective protection against the virus. “The only real protection is to develop rice varieties that possess a resistance gene against RYMV, which would make the plant invulnerable,” says Dr. Yugander Arra, lead author of the study now published in Plant Biotechnology Journal. A research team from the Institute for Molecular Physiology at HHU (headed by Professor Dr. Wolf B. Frommer) and the Institut de recherche pour le développement (IRD) in Montpellier, France, has developed such resistant rice lines. Three resistance genes are currently known; mutations in just one of the genes, called RYMV1, 2, and 3, are sufficient to achieve resistance. The resistant form rymv2 occurs in poor-yielding African rice (Oryza glaberrima) varieties. RYMV2, also known as CPR5.1, encodes an important protein from the pores of the cell nucleus. In the model plant Arabidopsis thaliana, the loss of the only gene copy of CPR5 results in a broad spectrum of resistance not only to viruses, but also to bacteria and fungi. However, growth is severely restricted, the plants exhibit spontaneous lesions and produce low yields. So it was important to test whether rymv2 resistance could be transferred to other rice varieties without negative consequences. Challenges and Solutions in Rice Breeding In Africa, other high-yield rice varieties based on the Asian species Oryza indica are mainly used and these do not have the resistance gene. Inserting the relevant gene is however not a particularly promising approach as the descendants of such “inter-species” hybrids are highly sterile and therefore cannot reproduce and pass on the resistance easily. Using the CRISPR/Cas genome editing method, the research group has now shown that mutations of the RYMV2 gene can be produced in an Asian rice variety that make it resistant to the virus in a similar way to the African form. In the next step, the aim is to edit relevant African elite varieties in the same way in order to then make them available to African small-scale producers. Helping these farmers is the goal of the international research consortium “Healthy Crops,” which is headed by HHU. Genetic Insights for Crop Improvement Plants have hereditary mechanisms that were useful for survival in the early days of evolution, but which are now more likely to be harmful. Maize is a good example of this: A gene causes the kernels to be aborted when drought conditions prevail at the time of fertilization. This trait caused by the gene was good for the wild perennial forebears of today’s maize plants, but has a detrimental effect on the yield of the annual plants now used in agriculture. The situation is similar with the rice examined here. Professor Frommer: “This resistance trait is attributable to the loss of a gene function that is not essential. If we switch the gene off completely, the plants behave normally. However, as a result of the loss of the gene function, they are resistant to the virus.” Dr. Eliza Loo, Healthy Crops Group Leader, adds: “It is so to speak an archetype, which was useful for its forebears, but which now leads to devastating crop losses in periods of drought. It would appear expedient to switch this gene off and it has no obvious side effects.” Promising Results and Future Directions Surprisingly, neither switching off the closely related CPR5.2 gene nor the two genes RYMV2 and CPR5.2 – at least under greenhouse conditions – leads to impairments. It is also noteworthy that the loss of CPR5.2 does not lead to RYMV resistance. Everything indicates that editing the RYMV2 gene is a promising approach to combating the rice disease in Africa. Reference: “Rice Yellow Mottle Virus resistance by genome editing of the Oryza sativa L. ssp. japonica nucleoporin gene OsCPR5.1 but not OsCPR5.2” by Yugander Arra, Florence Auguy, Melissa Stiebner, Sophie Chéron, Michael M. Wudick, Manuel Miras, Van Schepler-Luu, Steffen Köhler, Sébastien Cunnac, Wolf B. Frommer and Laurence Albar, 20 December 2023, Plant Biotechnology Journal. DOI: 10.1111/pbi.14266 The research took place within the framework of the Cluster of Excellence for Plant Research CEPLAS and was funded as part of Prof Frommer’s Alexander von Humboldt Professorship.

Attractive food smells are enough to blunt the life-extending effect of a restricted diet. A research team figured out why this is the case and whether the phenomenon could be blocked with a drug. The smell of food blocks the life-extending effect of a restricted diet. These drugs may unblock it. A research study using worms provides new clues about the role of serotonin and dopamine in aging. It’s common knowledge that a healthy diet is essential to a healthy life. And while many people follow specialized diets to trim down or improve their overall health, scientists interested in aging have been actively studying the life-extending effects of dietary restriction and fasting. “There’s a concept called hormesis in biology, the idea of which is what doesn’t kill you makes you stronger,” said Scott Leiser, Ph.D., an assistant professor in Molecular & Integrative Physiology, and Internal Medicine at University of Michigan Medical School. “One of the stresses that’s been most studied is dietary restriction, shown in many different organisms to extend lifespan and in people to improve health.” Related Anti-Aging Vitamins and Nutrients That Actually Work Cutting Calories and Eating at the Right Time of Day Leads to a Longer Life Potential Supplement for Longer Human Lifespans Adding a Particular Seafood to Your Diet Can Reverse Signs of Aging However, as anyone on a strict weight loss regimen can attest, the mere smell of delicious food can be enough to break one’s willpower. What’s more, previous research actually found that in fruit flies, attractive food smells are enough to blunt the life-extending effect of a restricted diet. That study was from Leiser’s colleague Scott Pletcher, Ph.D., also of the Department of Molecular & Integrative Physiology. Investigating the fmo-2 Gene in Lifespan Extension In a new study published on June 7, 2022, in Nature Communications, Leiser, first authors Hillary Miller, Ph.D., and Shijiao Huang, Ph.D., and their team build on that research to figure out why this is the case and whether a drug could block the phenomenon. In the roundworm C. elegans, lifespan extension in response to environmental stressors such as dietary restriction involves the activation of the fmo-2 gene. The researchers used the transparent nature of C. elegans to be able to see, in real time, the levels of FMO proteins. When worms were limited in the amount of food they could eat, the FMO protein, which was highlighted using a fluorescent marker, lit up “like a Christmas tree…it was bright red,” noted Leiser. However, when the worms were exposed to food smells, there was considerably less activation of FMO, leading to a loss of life extension. One of the main issues of dietary restriction as a potential approach for life extension in people is how difficult it is. But, said Leiser, “what if you could give yourself a drug that confused your body into thinking you were restricting your diet?” Drug Compounds That Mimic Dietary Restriction Building on earlier research showing that neurotransmitters regulate longevity resulting from dietary restriction, the team screened compounds known to act on neurons. They found three compounds that could prevent the reversal of fmo-2 induction in the presence of food: an antidepressant that blocks the neurotransmitter serotonin, and two antipsychotic drugs used to treat schizophrenia, both of which block the neurotransmitter dopamine. “We know serotonin and dopamine are major players in the reward portion of the brain and tend to be involved in satiety and food response signals,” said Leiser. “The fact that the drugs we found were antagonizing this suggests you are blocking aspects of these pathways.” Ultimately, the drugs enabled the life extension effect of FMO, even in the presence of the smell of food. These specific drugs are unlikely to be prescribed for this effect however, given their many potentially dangerous side effects. But they provide important clues about the fmo-2 activation pathway and its effect on life extension. Reference: “Serotonin and dopamine modulate aging in response to food odor and availability” by Hillary A. Miller, Shijiao Huang, Elizabeth S. Dean, Megan L. Schaller, Angela M. Tuckowski, Allyson S. Munneke, Safa Beydoun, Scott D. Pletcher and Scott F. Leiser, 7 June 2022, Nature Communications. DOI: 10.1038/s41467-022-30869-5

An illustration of Tiktaalik, an ancient species among one of the first to transition to land. A new study reveals clues how the first animals on land evolved to eat. Credit: Illustration by Kalliopi Monoyios Advanced Imaging, Modern Species Provide New Insights Into Behavior of Tiktaalik Roseae New research out of the University of Chicago has found evidence that the lobe-finned fish species Tiktaalik roseae was capable of both biting and suction during feeding, similar to modern-day fish called gars. Scientists had been curious how the first animals on land evolved to eat, because most water-dwellers use suction to pull in food—which doesn’t work on land. The new results, published in the Proceedings of the National Academy of Sciences, provide evidence that bite-based feeding originally evolved in aquatic species and was later adapted for use on land. Life at the Water-to-Land Transition T. roseae, a creature whose flat skull is reminiscent of an alligator, is a species that lived “right at the cusp of the transition from life in water to life on land,” said senior author Neil Shubin, the Robert R. Bensley Distinguished Service Professor of Organismal Biology and Anatomy at UChicago. Studying its fossilized remains can provide new insights into how key traits for life on land originally evolved. “Water is different from air, being much denser and more viscous,” said Justin Lemberg, a postdoctoral researcher at UChicago and first author of the study. “This would have created unique problems for animals that were moving out of water and onto land for the very first time, including challenges in locomotion, reproduction, maintaining homeostasis and sensory processing and, of course, feeding. If you can’t feed yourself on land, how can you colonize it?” High-speed video of a baby alligator gar using cranial kinesis, suction, and biting to capture prey (similar to the feeding strategy proposed for Tiktaalik roseae). Credit: Video courtesy of Justin Lemberg (University of Chicago). Most aquatic vertebrate species use suction feeding to help pull prey into their mouths. To create suction, many species of fish can expand their skulls laterally to expand their mouths and produce negative pressure. This movement of the skull bones relative to one another is called cranial kinesis. “Suction feeding is ineffective on land, because it no longer works from a distance and it’s hard to create the pressure seal needed to draw something in,” said Lemberg. “So terrestrial vertebrates had to turn to other methods to capture prey. But the fossil evidence for how this happened is ambiguous, much more so than the transition from fin to limb. We wanted to look specifically at the sutures in the T. roseae skull, where the bones fit together, to see if they could tell us how the skull was being used.” The research team used advanced new computed tomography (CT) analysis to conduct a detailed examination of the morphology of the T. roseae skull. This allowed them to identify key new traits that had not been seen with other techniques, including sliding joints that would have allowed for the necessary cranial kinesis for the animal to expand its skull laterally to create suction. “We discovered Tiktaalik in 2004 and at the time, prepared it with the classical methods, removing rock from the fossil grain by grain,” said Shubin. “By the time Justin joined the project, we had access to this CT scanning technology, which lets us see the skull in 3D, taking each part out individually to see its shape and motion. Using the CT analysis transformed how we were able to think about the skull.” Side-by-side comparison of Tiktaalik (top) and alligator gar (bottom) showing similarly shaped snouts that may suggest convergence in feeding strategies. Credit: Image courtesy of Justin Lemberg (University of Chicago) Investigators noted distinct similarities between T. roseae and earlier work analyzing the skulls of alligator gar, a “living fossil” species previously thought to only use lateral snapping motions to capture prey. In a 2019 study, Lemberg et. al. found that gar use lateral snapping and suction synergistically while feeding, thanks to unique sliding joints in their skulls that help create suction while biting. Long-Standing Evolutionary Innovation These similarities led the researchers to believe that T. roseae may have fed in the same way, indicating that this adaptation likely evolved long ago, before animals ever colonized land. Disarticulated CT-based model of the skull of the alligator gar, showing joints between functional regions of the skull responsible for cranial kinesis. Credit: Image courtesy of Justin Lemberg (University of Chicago) “The thing that really stuns me is that every innovation, every invention used by tetrapods on land, originally appeared in some form in fish, including lungs, appendages, and now, feeding,” said Shubin.  Beyond teaching us about the evolution of our distant, fishy ancestors, better understanding of the biology and behavior of creatures like T. roseae can provide new insights into our own anatomy and development. Personal Connections to Ancient Evolution “The neat thing about the water-to-land transition is that it’s deeply personal to us,” said Lemberg. “How did we get to where we are now, and what are some of the evolutionary quirks we’ve adapted to get here?” Disarticulated CT-based model of the skull of Tiktaalik roseae, showing joints between functional regions of the skull responsible for cranial kinesis. Credit: Image courtesy of Justin Lemberg (University of Chicago) Case in point: Lemberg pointed out that when analyzing the range of motion for the T. roseae skull, the three bones that appear to have moved the most are the bones that would eventually become incorporated into the mammalian middle ear. “Those three bones in Tiktaalik are what we use to hear sound,” Lemberg said. “A little bit of cranial kinesis that’s maintained in modern mammals!” The other author was Edward B. Daeschler of Drexel University. Reference: “The feeding system of Tiktaalik roseae: an intermediate between suction feeding and biting” by Justin B. Lemberg, Edward B. Daeschler, and Neil H. Shubin, 1 February 2021, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2016421118 Funding: Two anonymous donors; the Academy of Natural Sciences of Philadelphia; the Brinson Foundation; the Putnam Expeditionary Fund (Harvard University); the University of Chicago; the National Geographic Society Committee for Research and Exploration; the National Science Foundation.

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