Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Custom graphene foam processing China

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.ESG-compliant OEM manufacturer in Taiwan

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Orthopedic pillow OEM development factory Taiwan

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Flexible manufacturing OEM & ODM Thailand

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Pillow OEM factory for wellness brands

New research using electronic tags and sonar data shows that large marine predators like sharks and tunas often dive into the deep mesopelagic zone, interacting with its dense layer of organisms for feeding and possibly other purposes. This zone is crucial for both ecological balance and commercial fishing, requiring careful study and conservation to prevent irreversible damage. Data from over 300 tags on large marine predators, along with shipboard sonar, point to the ecological importance of the ocean’s twilight zone. If you’ve ever witnessed a shark breach the water—whether in person or somewhere on the Internet—that fleeting but awe-inspiring moment is just a small fraction of the time it spends at the surface of the ocean. Most of the time sharks and other large marine predators are out of sight, begging the question—where do they go? New Insights From a Comprehensive Study A new study demonstrates that large predatory fishes like sharks, tunas, and billfish make a surprising number of visits to the deep ocean—particularly the mesopelagic zone, which is found between 200 to 1,000 meters below the surface. This area, also called the ocean’s twilight zone, has been overlooked as critical habitat for large predator species, according to the study. The paper was published on November 6 in the journal Proceedings of the National Academy of Sciences. A new study demonstrates that large predatory fishes like sharks, tunas, and billfish make a surprising number of visits to the deep ocean—particularly the ocean’s twilight zone, which has been overlooked as critical habitat for large predator species. Credit: Tiger Shark /©Tom Burns Collaborative Research Efforts Led by Camrin Braun, an assistant scientist at the Woods Hole Oceanographic Institution (WHOI), the study incorporated an astonishing amount of data from multiple scientific partners. He and the co-authors synthesized data from electronic tags, shipboard sonar, Earth-observing satellites, and data-assimilating ocean models to quantify the ecological significance of deep diving for large pelagic predators. They emphasize that a healthy mesopelagic zone provides numerous benefits and ecosystem services to humans as well. Deep Ocean Habits of Predators “No matter what top predator you look at, or where you look at them in the global ocean, they all spend time in the deep ocean,” Braun said. “All of these animals that we think of as being residents of the surface ocean, use the deep ocean way more than we previously thought.” The scientists leveraged data from 344 electronic tags over the course of 46,659 tracking days for 12 species in the North Atlantic Ocean, including white sharks, tiger sharks, whale sharks, Yellowfin tuna, swordfish, and more. A new study demonstrates that large predatory fishes like sharks, tunas, and billfish make a surprising number of visits to the deep ocean—particularly the ocean’s twilight zone, which has been overlooked as critical habitat for large predator species. Credit: Blue Shark offshore, Cape Cod/© Eric Savetsky Understanding Deep Scattering Layer Movements The diving patterns of these fish recorded by the tags were then matched with sonar data that showed the daily movements of the deep scattering layer (DSL)—a zone where a huge number of small fish and marine organisms are packed so densely that scientists first using sonar mistook the layer for the ocean floor. During the day, animals in the DSL inhabit the mesopelagic zone. But when the sun sets, many of these individuals—like fish, mollusks, crustaceans, and others—swim to surface waters to feed. When the sun reemerges over the horizon, scattering light over the surface, they descend back to the twilight zone where they will remain until nightfall. This daily rhythm is called Diel Vertical Migration and is a pattern that scientists at WHOI have been studying for decades. Converging Data and Surprising Findings Alice Della Penna, co-author and collaborator at the University of Auckland, New Zealand, who specializes in acoustics, said that it was surprising to see the data sets match so well. “When we looked at this specific process from different perspectives, from the diving and the acoustics together, seeing that everything was falling into place was very exciting.” Feeding Patterns and Anomalous Behaviors After years of collecting and analyzing data, the new paper helps shed light on the predators who are attuned to the DSL, presumably to hunt smaller prey, and the animals who often diverge from the daily vertical migration patterns, leading to further questions about why they are diving so deep, if not to feed. “Several species aligned perfectly with the expectations that they’re diving to feed, but there are behaviors that aren’t just for feeding,” Braun said. Swordfish for example, follow the Diel Vertical Migration pattern like clockwork. But there are some “really surprising deviations from that behavior,” he explains—”like instead of diving down to 1,500 feet, a swordfish goes to 3,000 or 6,000 feet, much deeper than we would expect for that to be feeding behavior.” Exploring Other Motivations for Deep Diving That means they could be diving for other reasons that are not fully understood. Previous work has pointed to these vertical movements may be serving to avoid predators or aid in navigation, according to the study. Despite the anomalies, all of the large species included in the study interreacted with the mesopelagic organisms in one way or another, finding that it’s worth it for these predators to dive deep into a seemingly inhospitable part of the ocean where there is little light, the pressure is high and temperatures are near freezing. Ecosystem Services of the Mesopelagic Zone “Sharks and tunas are evolutionarily a long way apart with very different sensory systems. And yet still both of those groups find that it’s worthwhile to do that type of behavior,” said Simon Thorrold, fish ecologist at WHOI and co-author on the study. With the large number of fish and organisms making this trek, Thorrold said that these species are potentially moving a hefty amount of carbon dioxide from the surface into the deep ocean where it will stay for centuries—a potentially significant ecosystem service of the mesopelagic that is not yet quantified. Implications for Conservation and Commercial Fishing Since the twilight zone is clearly important to many large species that are fished commercially, “this deep-sea biomass contributes ecosystem services that are worth a considerable amount of money,” Thorrold, said. The paper stresses that it is in everyone’s interest to keep the mesopelagic intact, and that it is important to study these deep ocean food webs further before fishing or extracting activities occur. The paper states that “the overlap in ongoing fishing effort and pelagic predator distributions, expected climate-induced changes in pelagic ecosystems and the potential extraction of mesopelagic biomass,” can put this critical ecosystem in jeopardy. The Risks of Premature Exploitation “We’re finding that the mesopelagic is providing an important support for other parts of the ocean,” Della Penna said. “If we start to exploit these mesopelagic ecosystems before we know how they work, there’s a really big risk of causing damage that is not easily reversible.” Key Takeaways Data from electronic tags, shipboard acoustic data, Earth-observing satellites, and data-assimilating ocean models, find that the ocean’s mesopelagic zone, also called the twilight zone, is ecologically significant to many large marine fish that are thought of as surface dwellers. These large marine predators, like sharks and tunas, dive deep into the twilight zone, often to follow the movements of a dense layer of prey organisms, called the deep scattering layer. “Several species aligned perfectly with the expectations that they’re diving to feed, but there are behaviors that aren’t just for feeding,” lead author Camrin Braun said. Swordfish, for example, follow the Diel Vertical Migration pattern like clockwork. But there are some “really crazy deviations from that behavior,” meaning they could be diving for other reasons that are not fully understood. The paper stresses that it is in everyone’s interest to keep the mesopelagic zone intact, and it’s important to study these deep ocean food webs further before fishing or extracting activities occur. Reference: “Linking vertical movements of large pelagic predators with distribution patterns of biomass in the open ocean” by Camrin D. Braun, Alice Della Penna, Martin C. Arostegui, Pedro Afonso, Michael L. Berumen, Barbara A. Block, Craig A. Brown, Jorge Fontes, Miguel Furtado, Austin J. Gallagher, Peter Gaube, Walter J. Golet, Jeff Kneebone, Bruno C. L. Macena, Gonzalo Mucientes, Eric S. Orbesen, Nuno Queiroz, Brendan D. Shea, Jason Schratwieser, David W. Sims, Gregory B. Skomal, Derke Snodgrass and Simon R. Thorrold, 6 November 2023, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2306357120 Funding for this research was provided by The Coastal Research Fund in Support of Scientific Staff and the Investment in Science Fund at the Woods Hole Oceanographic Institution (to CDB), the WHOI President’s Innovation Fund and Postdoctoral Scholar Program at Woods Hole Oceanographic Institution with funding provided by the Dr. George D. Grice Postdoctoral Scholarship Fund (to MCA), UK Natural Environment Research Council (to DWS), the European Research Council (to DWS), a Marine Biological Association Senior Research Fellowship (to DWS) and the King Abdullah University of Science and Technology (baseline research funds to MLB). BCLM was supported by the projects IslandShark (PTDC/BIA-BMA/32204/2017), AEROS-Az (ACORES-01-0145-FEDER-000131), MEESO (EU H2020-LC-BG-03-2018), and Mission Atlantic (H2020-LC-BG-08-2018-862428). This work was part of the Woods Hole Oceanographic Institution’s Ocean Twilight Zone Project, funded as part of the Audacious Project housed at TED.

Scientists have created a potato super pangenome to identify traits for more resilient and nutritious potatoes. This extensive genetic database could aid in developing disease-resistant and climate-adaptive potatoes, benefiting global food security. Researchers have compiled the genome sequences of almost 300 types of potatoes and their wild cousins to create crops that are more nutritious, resistant to diseases, and resilient to weather conditions. As global warming increasingly threatens the stability of food sources worldwide, researchers from McGill University are exploring methods to enhance both the resilience and nutritional value of potatoes. Led by Professor Martina Strömvik, the team has developed a potato super pangenome to identify genetic characteristics that could pave the way for the next generation of super potatoes. “Our super pangenome sheds light on the potato’s genetic diversity and what kinds of genetic traits could potentially be bred into our modern-day crop to make it better,” says Professor Strömvik, who collaborated with researchers across Canada, the United States, and Peru. “It represents 60 species and is the most extensive collection of genome sequence data for the potato and its relatives to date,” she adds. A genome is an organism’s complete set of genetic instructions known as the DNA sequence, while a pangenome aims to capture the complete genetic diversity within a species, and a super pangenome also includes multiple species. Imagining a Disease-Free and Drought or Frost-Proof Potato The potato is a staple food source for many people around the world – and it’s one of the most important food crops globally, after rice and wheat in terms of human consumption. “Wild potato species can teach us a lot about what genetic traits are critical in adapting to climate change and extreme weather, enhancing nutritional quality, and improving food security,” says Professor Strömvik. To build the potato pangenome, the researchers used supercomputers to crunch data from public databanks, including gene banks in Canada, the United States, and Peru. According to the researchers, the pangenome can be used to answer many questions about the evolution of this important crop that was domesticated by Indigenous peoples in the mountains of southern Peru nearly 10,000 years ago. It could also be used to help identify specific genes to create a super spud using traditional breeding or gene editing technology. “Scientists hope to develop something that can defend against various forms of diseases and better withstand extreme weather like lots of rain, frost, or a drought,” says Professor Strömvik. Reference: “Pangenome analyses reveal impact of transposable elements and ploidy on the evolution of potato species” by Ilayda Bozan, Sai Reddy Achakkagari, Noelle L. Anglin, David Ellis, Helen H. Tai and Martina V. Strömvik, 24 July 2023, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2211117120

This is a histological image of a rat brain with a grafted human brain organoid. Credit: Jgamadze et al. Human Brain Organoids Intergate with Rat Brains and Respond to Visual Stimuli In a study published in the journal Cell Stem Cell on February 2, researchers show that brain organoids—clumps of lab-grown neurons—can integrate with rat brains and respond to visual stimulation like flashing lights. Decades of research has shown that we can transplant individual human and rodent neurons into rodent brains, and, more recently, it has been demonstrated that human brain organoids can integrate with developing rodent brains. However, whether these organoid grafts can functionally integrate with the visual system of injured adult brains has yet to be explored. “We focused on not just transplanting individual cells, but actually transplanting tissue,” says senior author H. Isaac Chen, a physician and Assistant Professor of Neurosurgery at the University of Pennsylvania. “Brain organoids have architecture; they have structure that resembles the brain. We were able to look at individual neurons within this structure to gain a deeper understanding of the integration of transplanted organoids.”  Integration of Organoids into Host Brain Networks The researchers cultivated human stem cell-derived neurons in the lab for around 80 days before grafting them into the brains of adult rats that had sustained injuries to their visual cortex. Within three months, the grafted organoids had integrated with their host’s brain: becoming vascularized, growing in size and number, sending out neuronal projections, and forming synapses with the host’s neurons. The team made use of fluorescent-tagged viruses that hop along synapses, from neuron to neuron, to detect and trace physical connections between the organoid and brain cells of the host rat. “By injecting one of these viral tracers into the eye of the animal, we were able to trace the neuronal connections downstream from the retina,” says Chen. “The tracer got all the way to the organoid.” Functional Response to Visual Stimuli Next, the researchers used electrode probes to measure the activity of individual neurons within the organoid when the animals were exposed to flashing lights and alternating white and black bars. “We saw that a good number of neurons within the organoid responded to specific orientations of light, which gives us evidence that these organoid neurons were able to not just integrate with the visual system, but they were able to adopt very specific functions of the visual cortex.” The team was surprised by the degree to which the organoids were able to integrate within only three months. “We were not expecting to see this degree of functional integration so early,” says Chen. “There have been other studies looking at transplantation of individual cells that show that even 9 or 10 months after you transplant human neurons into a rodent, they’re still not completely mature.” “Neural tissues have the potential to rebuild areas of the injured brain,” says Chen. “We haven’t worked everything out, but this is a very solid first step. Now, we want to understand how organoids could be used in other areas of the cortex, not just the visual cortex, and we want to understand the rules that guide how organoid neurons integrate with the brain so that we can better control that process and make it happen faster.” Reference: “Structural and functional integration of human forebrain organoids with the injured adult rat visual system” by Dennis Jgamadze, James T. Lim, Zhijian Zhang, Paul M. Harary, James Germi, Kobina Mensah-Brown, Christopher D. Adam, Ehsan Mirzakhalili, Shikha Singh, Jiahe Ben Gu, Rachel Blue, Mehek Dedhia, Marissa Fu, Fadi Jacob, Xuyu Qian, Kimberly Gagnon, Matthew Sergison, Oceane Fruchet, Imon Rahaman, Huadong Wang, Fuqiang Xu, Rui Xiao, Diego Contreras, John A. Wolf, Hongjun Song, Guo-li Ming and Han-Chiao Isaac Chen, 2 February 2023, Cell Stem Cell. DOI: 10.1016/j.stem.2023.01.004 This research was supported by the Department of Veterans Affairs, National Institutes of Health, and the Dr. Miriam and Sheldon G. Adelson Medical Research Foundation.

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