Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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China OEM insole and pillow supplier

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Taiwan graphene material ODM solution

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Thailand flexible graphene product manufacturing

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Indonesia athletic insole OEM supplier

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Taiwan insole OEM manufacturing factory

Ancient horses crossed over the Bering Land Bridge in both directions between North America and Asia multiple times during the Pleistocene. Credit: Illustration by Julius Csotonyi New findings show connections between the ancient horse populations in North America, where horses evolved, and Eurasia, where they were domesticated. A new study of ancient DNA from horse fossils found in North America and Eurasia shows that horse populations on the two continents remained connected through the Bering Land Bridge, moving back and forth and interbreeding multiple times over hundreds of thousands of years. The new findings demonstrate the genetic continuity between the horses that died out in North America at the end of the last ice age and the horses that were eventually domesticated in Eurasia and later reintroduced to North America by Europeans. The study has been accepted for publication in the journal Molecular Ecology and is currently available online. Paleontologist Aisling Farrell holds a mummified frozen horse limb recovered from a placer gold mine in the Klondike goldfields in Yukon Territory, Canada. Ancient DNA recovered from horse fossils reveals gene flow between horse populations in North America and Eurasia. Credit: Government of Yukon “The results of this paper show that DNA flowed readily between Asia and North America during the ice ages, maintaining physical and evolutionary connectivity between horse populations across the Northern Hemisphere,” said corresponding author Beth Shapiro, professor of ecology and evolutionary biology at UC Santa Cruz and a Howard Hughes Medical Institute investigator. The study highlights the importance of the Bering Land Bridge as an ecological corridor for the movement of large animals between the continents during the Pleistocene, when massive ice sheets formed during glacial periods. Dramatically lower sea levels uncovered a vast land area known as Beringia, extending from the Lena River in Russia to the MacKenzie River in Canada, with extensive grasslands supporting populations of horses, mammoths, bison, and other Pleistocene fauna. Paleontologists have long known that horses evolved and diversified in North America. One lineage of horses, known as the caballine horses (which includes domestic horses) dispersed into Eurasia over the Bering Land Bridge about 1 million years ago, and the Eurasian population then began to diverge genetically from the horses that remained in North America. The new study shows that after the split, there were at least two periods when horses moved back and forth between the continents and interbred, so that the genomes of North American horses acquired segments of Eurasian DNA and vice versa. “This is the first comprehensive look at the genetics of ancient horse populations across both continents,” said first author Alisa Vershinina, a postdoctoral scholar working in Shapiro’s Paleogenomics Laboratory at UC Santa Cruz. “With data from mitochondrial and nuclear genomes, we were able to see that horses were not only dispersing between the continents, but they were also interbreeding and exchanging genes.” Mitochondrial DNA, inherited only from the mother, is useful for studying evolutionary relationships because it accumulates mutations at a steady rate. It is also easier to recover from fossils because it is a small genome and there are many copies in every cell. The nuclear genome carried by the chromosomes, however, is a much richer source of evolutionary information. Alisa Vershinina works in the Paleogenomics Lab at UC Santa Cruz where ancient DNA is extracted from fossils for sequencing and analysis. Credit: UC Santa Cruz The researchers sequenced 78 new mitochondrial genomes from ancient horses found across Eurasia and North America. Combining those with 112 previously published mitochondrial genomes, the researchers reconstructed a phylogenetic tree, a branching diagram showing how all the samples were related. With a location and an approximate date for each genome, they could track the movements of different lineages of ancient horses. “We found Eurasian horse lineages here in North America and vice versa, suggesting cross-continental population movements. With dated mitochondrial genomes we can see when that shift in location happened,” Vershinina explained. The analysis showed two periods of dispersal between the continents, both coinciding with periods when the Bering Land Bridge would have been open. In the Middle Pleistocene, shortly after the two lineages diverged, the movement was mostly east to west. A second period in the Late Pleistocene saw movement in both directions, but mostly west to east. Due to limited sampling in some periods, the data may fail to capture other dispersal events, the researchers said. The team also sequenced two new nuclear genomes from well-preserved horse fossils recovered in Yukon Territory, Canada. These were combined with 7 previously published nuclear genomes, enabling the researchers to quantify the amount of gene flow between the Eurasian and North American populations. “The usual view in the past was that horses differentiated into separate species as soon as they were in Asia, but these results show there was continuity between the populations,” said coauthor Ross MacPhee, a paleontologist at the American Museum of Natural History. “They were able to interbreed freely, and we see the results of that in the genomes of fossils from either side of the divide.” The new findings are sure to fuel the ongoing controversy over the management of wild horses in the United States, descendants of domestic horses brought over by Europeans. Many people regard those wild horses as an invasive species, while others consider them to be part of the native fauna of North America. “Horses persisted in North America for a long time, and they occupied an ecological niche here,” Vershinina said. “They died out about 11,000 years ago, but that’s not much time in evolutionary terms. Present-day wild North American horses could be considered reintroduced, rather than invasive.” Coauthor Grant Zazula, a paleontologist with the Government of Yukon, said the new findings help reframe the question of why horses disappeared from North America. “It was a regional population loss rather than an extinction,” he said. “We still don’t know why, but it tells us that conditions in North America were dramatically different at the end of the last ice age. If horses hadn’t crossed over to Asia, we would have lost them all globally.” Reference: “Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge” by Alisa O. Vershinina, Peter D. Heintzman, Duane G. Froese, Grant Zazula, Molly Cassatt-Johnstone, Love Dalén, Clio Der Sarkissian, Shelby G. Dunn, Luca Ermini, Cristina Gamba, Pamela Groves, Joshua D. Kapp, Daniel H. Mann, Andaine Seguin-Orlando, John Southon, Mathias Stiller, Matthew J. Wooller, Gennady Baryshnikov, Dmitry Gimranov, Eric Scott, Elizabeth Hall, Susan Hewitson, Irina Kirillova, Pavel Kosintsev, Fedor Shidlovsky, Hao-Wen Tong, Mikhail P. Tiunov, Sergey Vartanyan, Ludovic Orlando, Russell Corbett-Detig, Ross D. MacPhee and Beth Shapiro, 10 May 2021, Molecular Ecology. DOI: 10.1111/mec.15977 This project was a large international collaborative effort involving researchers at multiple institutions working together to obtain DNA from fossils of ancient horses over a wide range of sites in Eurasia and North America. The coauthors include researchers from the University of Toulouse, France, the Arctic University of Norway, and other institutions in the United States, Canada, Sweden, Denmark, Germany, Russia, and China. This work was supported in part by the U.S. National Science Foundation, Gordon & Betty Moore Foundation, and the American Wild Horse Campaign.

Apennine brown bears have a specific genetic mutation within their mitochondria – the “powerhouses” of cells – that potentially impacts their overall health and survival. Credit: Nunzio Perta Only about 50 Apennine brown bears remain in the wild, and new research sheds light on a key challenge to their survival. The Apennine brown bear, also known as the Marsican brown bear (Ursus arctos marsicanus), is a critically endangered subspecies of brown bear found exclusively in the remote Apennine Mountains of central Italy. A recent study by the Italian Endemixit project (endemixit.com) has identified a potentially significant genetic vulnerability within this isolated population. These findings could provide valuable insights for conservation efforts. The research was recently presented at the 69th Biophysical Society Annual Meeting. This distinct population has been isolated for centuries, evolving unique physical characteristics and behaviors that set it apart from other brown bears. With an estimated population of only around 50 individuals, the Apennine brown bear faces a severe risk of extinction due to habitat loss, human encroachment, and genetic vulnerability. Conservation efforts are crucial to safeguarding this species, which plays a vital role in the delicate ecological balance of its mountainous habitat. Discovery of a Genetic Flaw The new research identified a specific genetic mutation within mitochondria – the “powerhouses” of cells – that impairs the bears’ cellular energy production, potentially impacting their overall health and survival. The mutation is in the ND5 subunit of Respiratory Complex I. Additionally, using a combination of advanced computer modeling and laboratory experiments, the researchers found that this mutation disrupts the function of mitochondria, leading to reduced energy production and increased harmful byproducts like reactive oxygen species. It’s like a factory with a broken generator: it produces less power and more pollution. The Impact on Bear Survival “This mutation appears to significantly impact these bears,” explained Nunzio Perta, a graduate student in the lab of Daniele Di Marino at the Marche Polytechnic University, in Ancona, Italy. “It’s like they’re constantly running on low batteries. This could make it harder for them to survive, especially in a challenging environment.” But because they’ve noted that the bears make more reactive oxygen species as a result of this mutation, other researchers are now exploring ways that they might help the bears process these harmful byproducts. One way to do that, Perta explained, is by helping them eat more food with antioxidants in it, perhaps by planting more native berry plants in their habitat. “By understanding the molecular basis of these genetic problems, we hope to create a plan to protect these bears in their natural environment,” said Perta. He added, “The bears are a crucial part of the very unique ecosystem that we have here in Italy.” Meeting: 69th Biophysical Society Annual Meeting

A new theory suggests the utility of a memory for future situations dictates its location in the brain, either in the hippocampus or the neocortex. This challenges the classical view by emphasizing that memories consolidate to the neocortex based on their generalizability, not age. A New Theory on Memory Storage in the Brain According to a new theory presented by researchers at HHMI’s Janelia Research Campus and their colleagues at University College London, how useful a memory is for future situations determines where it resides in the brain. The theory offers a new way of understanding systems consolidation, a process that transfers certain memories from the hippocampus – where they are initially stored – to the neocortex — where they reside long term. Under the classical view of systems consolidation, all memories move from the hippocampus to the neocortex over time. But this view doesn’t always hold up; research shows some memories permanently reside in the hippocampus and are never transferred to the neocortex. In recent years, psychologists proposed theories to explain this more complicated view of systems consolidation, but no one has yet figured out mathematically what determines whether a memory stays in the hippocampus or whether it is consolidated in the neocortex. A Mathematical Approach to Understanding Memory Consolidation Now, Janelia researchers are putting forward a new, quantitative view of systems consolidation to help resolve this longstanding problem, proposing a mathematical neural network theory in which memories consolidate to the neocortex only if they improve generalization. Generalizations are constructed from the reliable and predictable components of memories, enabling us to apply them to other situations. We can generalize certain features of memories to help us understand the world, like the fact that canyons predict the presence of water. This is different from episodic memories — detailed recollections of the past that have unique features like an individual memory we have of hiking to a particular canyon and coming upon a body of water. Under this view, consolidation doesn’t copy memories from one area of the brain to another but rather creates a new memory that is a generalization of previous memories. The amount that a memory can be generalized – not its age — determines whether it is consolidated or remains in the hippocampus. The researchers used neural networks to show how the amount of consolidation varies based on how much of a memory is generalizable. They were able to reproduce previous experimental patterns that couldn’t be explained by the classical view of systems consolidation. The next step is to test the theory with experiments to see if it can predict how much a memory will be consolidated. Another important direction will be to test the authors’ models of how the brain might distinguish between predictable and unpredictable components of memories to regulate consolidation. Uncovering how memory works can help researchers better understand an integral part of cognition, potentially benefitting human health and artificial intelligence. Reference: “Organizing memories for generalization in complementary learning systems” by Weinan Sun, Madhu Advani, Nelson Spruston, Andrew Saxe and James E. Fitzgerald, 20 July 2023, Nature Neuroscience. DOI: 10.1038/s41593-023-01382-9

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