Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Custom graphene foam processing factory Taiwan

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Insole ODM factory in Vietnam

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.PU insole OEM production in Indonesia

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Pillow OEM for wellness brands China

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Vietnam sustainable material ODM solutions

A sidewinder snake is shown in a sand-filled arena that researchers used to understand the unique motion they use to climb sandy slopes. Credit: Rob Felt, Georgia Tech Sidewinder snakes evolved unique belly textures to support sideways locomotion, offering insights for bio-inspired robotics. The mesmerizing flow of a sidewinder moving obliquely across desert sands has captivated biologists for centuries and has been variously studied over the years, but questions remain about how the snakes produce their unique motion. Sidewinders are pit vipers, specifically rattlesnakes, native to the deserts of the southwestern United States and adjacent Mexico. Scientists had already described the microstructure of the skin on the ventral, or belly, surface of snakes. Many of the snakes studied, including all viper species, had distinctive rearward facing “microspicules” (micron-sized protrusions on scales) that had been interpreted in the context of reducing friction in the forward direction—the direction the crawling snake—and increasing friction in the backward direction to reduce slip.  Considered through the lens of a sidewinder’s peculiar form of locomotion, however, it seemed that these microspicules would not function in the same manner. But no one had examined the microstructure of sidewinders, nor of a handful of unrelated African vipers that also sidewind. Working with naturally-shed skins collected from snakes in zoos, researchers used atomic force microscopy to visualize and measure the microstructures of these scale protrusions in three species of sidewinding vipers as well as many other viper species for comparison. The results of the research, published this week in the journal Proceedings of the National Academy of Sciences, found that indeed the sidewinders have a unique structure distinct from other snakes.  Image shows scale microstructures found on sidewinder snakes. The structures differ from those of other snakes, and researchers believe those differences allow the unique movement of sidewinders on sand. Credit: Tai-De Li Cratered Textures Replace Microspicules The microspicules were absent in the African sidewinding species and reduced to tiny nubbins in the North American sidewinder. All three snakes also had distinctive crater-like micro-depressions producing a distinctive texture not seen in other snakes.  Daniel Goldman, Dunn Family Professor of Physics at the Georgia Institute of Technology, and Jennifer Rieser, working as a postdoctoral researcher in Goldman’s group and currently an assistant professor in the Department of Physics at Emory University, developed mathematical models to test how both the typical texture of rearward-directed microspicules and spicule-less cratered texture function as snakes interact with the ground. The models revealed that the microspicules would actually impede sidewinding, explaining their evolutionary loss in these species.  The models also revealed an unexpected result that microspicules function to improve performance of snakes that use lateral undulation to move. Lateral undulation is the typical side-to-side mode locomotion used by the majority of snake species. “This discovery adds a new dimension to our knowledge of the functionality of these structures, that is more complex than the previous ideas,” said Joseph Mendelson, director of research at Zoo Atlanta and adjunct associate professor in the Georgia Tech School of Biological Sciences. Image shows the microstructure of belly scales found on the Mexican lance-headed rattlesnake. The structures were different from those found on other snakes. Credit: Tai-De Li Textured Scales Function Like Corduroy The models indicate that the microspicules act a bit like corduroy fabric. “Friction is low when you run your finger along the length of the furrowed fabric—consistent with previous work—but the furrows produce significant friction when you move your finger sideways across the fabric texture,” said Goldman. The functionality of the distinct craters remains a mystery. The findings could be important to the development of future generations of robots able to move across challenging surfaces such as loose sand. “Understanding how and why this example of convergent evolution works may allow us to adapt it for our own needs, such as building robots that can move in challenging environments,” Rieser said. A Case of Convergent Evolution In terms of anatomy, this was a classic example of convergent evolution between a pair of snake species in Africa and a very distantly related snake in North America, Mendelson noted. Biogeographic reconstructions conducted by Jessica Tingle, a doctoral student at University of California Riverside, indicated that the African snakes are evolutionarily much older than the North American sidewinder, suggesting that the sidewinders represented an earlier phase in adaptation for sidewinding. Tai-De Li, then at Georgia Tech in the lab of Prof Elisa Riedo and now at the City University of New York, did the AFM measurements.  Drawing from the fields of evolutionary biology, living systems physics, and mathematical modeling, the team produced a study that explains some aspects of what these microstructures on the bellies of snakes do and how they evolved in snakes.  “Our results highlight how an integrated approach can provide quantitative predictions for structure-function relationships and insights into behavioral and evolutionary adaptions in biological systems,” the authors wrote.  For more on this research, read Physics of Snakeskin Sheds Light on Specialized Sidewinding Locomotion of Sidewinder Snakes. Reference: “Functional consequences of convergently evolved microscopic skin features on snake locomotion” by Jennifer M. Rieser, Tai-De Li, Jessica L. Tingle, Daniel I. Goldman and Joseph R. Mendelson III, 1 February 2021, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2018264118 This research was supported by the Georgia Tech Elizabeth Smithgall Watts Fund; National Science Foundation Physics of Living Systems Grants PHY-1205878 and PHY-1150760; and Army Research Office Grant W911NF-11-1-0514. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the sponsoring agencies.

Variations in Earth’s orbit have influenced the evolution of coccolithophores. Coccolithophores are microscopic algae that form tiny limestone plates, called coccoliths, around their single cells. The shape and size of coccoliths varies according to the species. After their death, coccolithophores sink to the bottom of the ocean and their coccoliths accumulate in sediments, which faithfully record the detailed evolution of these organisms over geological time. A team of scientists led by CNRS researchers[1] show, in an article published in Nature on the 1st of December 2021, that certain variations in Earth’s orbit have influenced the evolution of coccolithophores. To achieve this, no less than 9 million coccoliths, spanning an interval of 2.8 million years and several locations in the tropical ocean, were measured and classified using automated microscope techniques and artificial intelligence. Coccolithophores, an important constituent of the plankton, evolved following the rhythm of Earth’s orbital eccentricity. Credit: Luc Beaufort / CNRS / CEREGE The researchers observed that coccoliths underwent cycles of higher and lower diversity in size and shape, with rhythms of 100 and 400 thousand years. They also propose a cause: the more or less circular shape of Earth’s orbit around the Sun, which varies at the same rhythms. Thus, when Earth’s orbit is more circular, as is the case today (this is known as low eccentricity), the equatorial regions show little seasonal variation, and species that are not very specialized dominate all the oceans. Conversely, as eccentricity increases and more pronounced seasons appear near the equator, coccolithophores diversify into many specialized species, but collectively produce less limestone. Crucially, due to their abundance and global distribution, these organisms are responsible for half of the limestone (calcium carbonate, partly composed of carbon) produced in the oceans and therefore play a major role in the carbon cycle and in determining ocean chemistry. The diversity of coccolithophores and their collective limestone production evolved under the influence of Earth’s orbital eccentricity, which determines the intensity of seasonal variations near the equator. On the other hand, no link to global ice volume or temperature was found. It was therefore not global climate change that dictated micro-algae evolution but perhaps the opposite during certain periods. Credit: Luc BEAUFORT / CNRS / CEREGE It is therefore likely that the cyclic abundance patterns of these limestone producers played a key role in ancient climates, and may explain hitherto mysterious climate variations in past warm periods. In other words, in the absence of ice, the biological evolution of micro-algae could have set the tempo of climates. This hypothesis remains to be confirmed. Notes Based at Centre Européen de Recherche et d’Enseignement des Géosciences de l’Environnement (CNRS/Aix-Marseille Université/IRD/INRAE/Collège de France) and in collaboration with scientists from Rutgers University (USA). Reference: “Cyclic evolution of phytoplankton forced by changes in tropical seasonality” by Luc Beaufort, Clara T. Bolton, Anta-Clarisse Sarr, Baptiste Suchéras-Marx, Yair Rosenthal, Yannick Donnadieu, Nicolas Barbarin, Samantha Bova, Pauline Cornuault, Yves Gally, Emmeline Gray, Jean-Charles Mazur and Martin Tetard, 1 December 2021, Nature. DOI: 10.1038/s41586-021-04195-7

New research by MIT reveals how environment and state are integrated to control behavior. They looked, in detail, at the mechanisms that control the levels of a single olfactory receptor in a single olfactory neuron of the C. elegans worm based on the ongoing state and stimuli experienced. A simple animal model shows how stimuli and states such as smells, stressors, and satiety converge in an olfactory neuron to guide food-seeking behavior. Imagine you live across from a bakery. Sometimes you are hungry and therefore tempted when aromas waft through your window. However, other times satiety makes you uninterested. Sometimes popping over for a popover seems trouble-free, but sometimes your spiteful ex is there. Your brain balances many influences in determining what you’ll do. An example of this working in a much simpler animal is detailed in a new MIT study. It highlights a potentially fundamental principle of how nervous systems integrate multiple factors to guide food-seeking behavior. All animals share the challenge of weighing diverse sensory cues and internal states when formulating behaviors, but scientists know little about how this actually occurs. To gain deep insight, the research team based at The Picower Institute for Learning and Memory turned to the C. elegans worm, whose well-defined behavioral states and 302-cell nervous system make the complex problem at least tractable. They emerged with a case study of how, in a crucial olfactory neuron called AWA, many sources of state and sensory information converge to independently throttle the expression of a key smell receptor. The integration of their influence on that receptor’s abundance then determines how AWA guides roaming around for food. The neuron AWA stretches from a worm’s brain to its nose. A new study shows that the brain routes many internal states and sensory cues to this neuron, affecting expression of a smell receptor. The sum total of these influences dictate food-seeking behavior. Credit: Ian McLachlan/The Picower Institute AWA Neurons and STR-44 Receptors “In this study, we dissected the mechanisms that control the levels of a single olfactory receptor in a single olfactory neuron, based on the ongoing state and stimuli the animal experiences,” says senior author Steven Flavell, Lister Brothers Associate Professor in MIT’s Department of Brain and Cognitive Sciences. “Understanding how the integration happens in one cell will point the way for how it may happen in general, in other worm neurons and in other animals.” MIT postdoc Ian McLachlan led the study, which was recently published in the journal eLife. He said the team didn’t necessarily know what they’d find out when they began. “We were surprised to find that the animal’s internal states could have such an impact on gene expression at the level of sensory neurons — essentially, hunger and stress caused changes in how the animal senses the outside world by changing what sensory neurons respond to,” he says. “We were also excited to see that the chemoreceptor expression wasn’t just depending on one input, but depended on the sum total of external environment, nutritional status, and levels of stress. This is a new way to think about how animals encode competing states and stimuli in their brains.” Hunger’s Impact on Sensory Perception Indeed McLachlan, Flavell, and their team didn’t go looking specifically for the neuron AWA or the specific olfactory chemoreceptor, dubbed STR-44. Instead, those targets emerged from the unbiased data they collected when they looked at what genes changed in expression the most when worms were kept from food for three hours compared to when they were well-fed. As a category, genes for many chemosensory receptors showed huge differences. AWA proved to be a neuron with a large number of these up-regulated genes and two receptors, STR-44 and SRD-28, appeared especially prominent among those. This result alone showed that an internal state (hunger) influenced the degree of receptor expression in a sensory neuron. McLachlan and his co-authors were then able to show that STR-44 expression also independently changed based on the presence of a stressful chemical, based on a variety of food smells, and on whether the worm had received the metabolic benefits of eating food. Further tests led by co-second author Talya Kramer, a graduate student, revealed which smells trigger STR-44, allowing the researchers to then demonstrate how changes in STR-44 expression within AWA directly affected food-seeking behavior. And yet more research identified the exact molecular and circuit means by which these varying signals get to AWA and how they act within the cell to change STR-44 expression. Stress and Sensory Trade-offs For example, in one experiment McLachlan and Flavell’s team showed that while both fed and hungry worms would wriggle toward the receptors’ favorite smells if they were strong enough, only fasted worms (which express more of the receptor) could detect fainter concentrations. In another experiment, they found that while hungry worms will slow down to eat upon reaching a food source even as well-fed worms cruise on by, they could make well-fed worms act like fasted ones by artificially overexpressing STR-44. Such experiments demonstrated that STR-44 expression changes have a direct effect on food-seeking. Other experiments showed how multiple factors push and pull on STR-44. For instance, they found that when they added a chemical that stresses the worms, that ratcheted down STR-44 expression even in fasted worms. And later they showed that the same stressor suppressed the worms’ urge to wriggle toward the odor that STR-44 responds to. So just like you might avoid following your nose to the bakery, even when hungry, if you see your ex there, worms weigh sources of stress against their hunger when deciding whether to approach food. They do so, the study shows, based on how these different cues and states push and pull on STR-44 expression in AWA. Decoding Neural Pathways and Molecular Levers Several other experiments examined the pathways of the worm’s nervous system that bring sensory, hunger, and active eating cues to AWA. Technical assistant Malvika Dua helped to reveal how other food-sensing neurons affect STR-44 expression in AWA via insulin signaling and synaptic connections. Cues about whether the worm is actively eating come to AWA from neurons in the intestine that use a molecular nutrient sensor called TORC2. These, and the stress-detecting pathway, all acted on FOXO, which is a regulator of gene expression. In other words, all the inputs that affect STR-44 expression in AWA were doing so by independently pushing and pulling on the same molecular lever. Flavell and McLachlan note that pathways such as insulin and TORC2 are present in not only other worm sensory neurons but also many other animals, including humans. Moreover, sensory receptors were up-regulated by fasting in more neurons than just AWA. These overlaps suggest that the mechanism they discovered in AWA for integrating information is likely at play in other neurons and maybe in other animals, Flavell says. And, McLachlan adds, basic insights from this study could help inform research on how gut-brain signaling via TORC2 works in people. “This is emerging as a major pathway for gut-to-brain signaling in C. elegans, and I hope it will ultimately have translational importance for human health,” McLachlan says. Reference: “Diverse states and stimuli tune olfactory receptor expression levels to modulate food-seeking behavior” by Ian G McLachlan, Talya S Kramer, Malvika Dua, Elizabeth M DiLoreto, Matthew A Gomes, Ugur Dag, Jagan Srinivasan and Steven W Flavell, 31 August 2022, eLife. DOI: 10.7554/eLife.79557 In addition to McLachlan, Flavell, Kramer, and Dua, the paper’s other authors are Matthew Gomes and Ugur Dag of MIT and Elizabeth DiLoreto and Jagan Srinivasan of Worcester Polytechnic Institute. The JPB Foundation, the National Institutes of Health, the National Science Foundation, the McKnight Foundation, and the Alfred P. Sloan Foundation provided funding for the study.

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