Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Graphene cushion OEM factory in Taiwan

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Private label insole and pillow OEM Vietnam

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Graphene sheet OEM supplier Vietnam

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Taiwan OEM/ODM hybrid insole development factory

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Insole ODM factory in Taiwan

A team of biologists led by The University of Texas at Arlington has discovered a new tiny lizard species in the Paria Peninsula of northeastern Venezuela. This discovery, published in the Zoological Journal of the Linnean Society, highlights the unique characteristics of this gecko, including its small size (about 2.5 inches long), brown color, cone-shaped head, long snout and particular skull anatomy. Credit: UT Arlington New gecko species discovered in Venezuela’s Paria Peninsula exhibits unique anatomical features, highlighting the area’s biodiversity and the urgent need for protective conservation measures. A team of scientists led by The University of Texas at Arlington has discovered a new gecko species, Pseudogonatodes fuscofortunatus, in Venezuela’s Paria Peninsula. The species, described in a study published in the Zoological Journal of the Linnean Society, is characterized by its small size (approximately 2.5 inches long), brown color, cone-shaped head, long snout, and unique skull anatomy. A new species of gecko, Pseudogonatodes fuscofortunatus, was identified through a combination of visual examination, molecular genetics and high-resolution X-ray computed tomography (CT) scans. Part of what makes this gecko unique is its distinct skeletal features, including fully separated nasal bones and fused parietal bones—uncommon traits among similar geckos. These characteristics, along with genetic data, distinguish it from other species within the genus Pseudogonatodes. Credit: UT Arlington Unique Characteristics and Identification Techniques Pseudogonatodes fuscofortunatus was identified through a combination of visual examination, molecular genetics, and high-resolution X-ray computed tomography (CT) scans. Its unique skeletal features, such as fully separated nasal bones and fused parietal bones—rare traits among similar geckos—along with genetic data, set it apart from other species within the genus Pseudogonatodes. Walter Schargel with samples of the new gecko species. Credit: UT Arlington Significance of the Paria Peninsula The discovery was made during fieldwork in the evergreen forests of the slopes of mountains in the Paria Peninsula, an area in northeastern Venezuela that juts into the Caribbean Sea and is known for its high biodiversity, moderate temperatures, and lush vegetation. The researchers collected specimens in 2002 and again in 2014, noting the gecko’s unique skull structure, which led to further investigation. The species name, fuscofortunatus, reflects the brown coloration of the gecko and the fortunate circumstances of its discovery. “The Paria Peninsula, part of the Coastal Mountain Range of Venezuela, has been a hotspot for reptile and amphibian discoveries in recent decades,” said the study’s lead author Walter E. Schargel, a professor of instruction in biology and earth and environmental sciences at UT Arlington. “The region’s complex geography and climate create diverse habitats that can support a wide range of species. The new gecko species adds to the growing list of reptiles that live only in this area, emphasizing the need for continued exploration and conservation efforts in the region.” “The Paria Peninsula, part of the Coastal Mountain Range of Venezuela, has been a hotspot for reptile and amphibian discoveries in recent decades,” said the study’s lead author Walter E. Schargel, a professor of instruction in biology and earth and environmental sciences at UT Arlington. “The region’s complex geography and climate create diverse habitats that can support a wide range of species. The new gecko species adds to the growing list of reptiles that live only in this area, emphasizing the need for continued exploration and conservation efforts in the region.” Credit: UT Arlington Implications for Conservation and Further Research The research team included experts from various institutions in the United States, Portugal, Spain, Brazil, Colombia, and Venezuela. Their collaborative efforts and combined field observations, museum specimen comparisons, DNA sequencing, and advanced imaging techniques led to a comprehensive description of the new species. “This discovery not only enriches our understanding of the biodiversity in this part of Venezuela, but it underscores the significance of preserving these unique ecosystems,” said Dr. Schargel. “I hope this discovery fuels increased conservation measures to protect the habitats of this rare species and other native species in the region.” The study highlights the potential for further discoveries in the Paria Peninsula and similar areas, where many animal species remain undocumented. The use of modern technologies, such as CT scanning and molecular genetic analysis, plays a crucial role in uncovering the hidden diversity of life on Earth, offering new insights into the evolutionary history and ecological adaptations of these fascinating creatures. Reference: “Morphology and molecular systematics support a new species of Pseudogonatodes (Squamata: Gekkota: Sphaerodactylidae) from Venezuela with a remarkable telescoped skull” by Walter E Schargel, Cristian Hernández-Morales, Juan D Daza, Michael J Jowers, Andrés Camilo Montes-Correa, Mayke De Freitas, Kathryn A Sullivan, Tony Gamble, Aaron M Bauer and Gilson A Rivas, 16 October 2024, Zoological Journal of the Linnean Society. DOI: 10.1093/zoolinnean/zlae120 Funding for the project came from the U.S. National Science Foundation, a Biodiversity Consultancy grant through Oro Verde and Fundacion Proyecto Paria, the EDGE program of the Zoological Society of London, and Fondation Segre.

Scientists have developed a revolutionary technique, termed “transient-naive-treatment (TNT) reprogramming.” This method allows human cells to be reprogrammed to more closely resemble embryonic stem cells, addressing a longstanding issue in regenerative medicine. The team’s breakthrough promises to set new standards for cell therapies and research. (Human iPS cells.) Credit: Jia Tan, Polo Laboratory A new method to reprogram human cells to better mimic embryonic stem cells. In a groundbreaking study published on August 16 in the journal Nature, Australian scientists have resolved a long-standing problem in regenerative medicine. They developed a new method to reprogram human cells to better mimic embryonic stem cells, with significant implications for biomedical and therapeutic uses. The team of researchers was led by Professor Ryan Lister from the Harry Perkins Institute of Medical Research and The University of Western Australia and Professor Jose M Polo from Monash University and the University of Adelaide. History and Challenges of Cell Reprogramming In a revolutionary advance in the mid-2000s, it was discovered that the non-reproductive adult cells of the body, called ‘somatic’ cells, could be artificially reprogrammed into a state that resembles embryonic stem (ES) cells which have the capacity to then generate any cell of the body. The transformative ability to artificially reprogram human somatic cells, such as skin cells, into these so-called induced pluripotent stem (iPS) cells provided a way to make an essentially unlimited supply of ES-like cells. This has widespread applications in disease modeling, drug screening, and cell-based therapies. “However, a persistent problem with the conventional reprogramming process is that iPS cells can retain an epigenetic memory of their original somatic state, as well as other epigenetic abnormalities,” Professor Lister said. “This can create functional differences between the iPS cells and the ES cells they’re supposed to imitate, and specialized cells subsequently derived from them, which limits their use.” Introducing the TNT Reprogramming Technique Professor Jose Polo, who is also with the Monash Biomedicine Discovery Institute, explained that they have now developed a new method, called transient-naive-treatment (TNT) reprogramming, that mimics the reset of a cell’s epigenome that happens in very early embryonic development. “This significantly reduces the differences between iPS cells and ES cells and maximizes the effectiveness of how human iPS cells can be applied,” he said. Dr. Sam Buckberry, a computational scientist from the Harry Perkins Institute, UWA, and Telethon Kids Institute, and co-first author of the study, said by studying how the somatic cell epigenome changed throughout the reprogramming process, they pinpointed when epigenetic aberrations emerged, and introduced a new epigenome reset step to avoid them and erase the memory. Dr. Xiaodong Liu, a stem cell scientist who also spearheaded the research said the new human TNT-iPS cells much more closely resembled human ES cells – both molecularly and functionally – than those produced using conventional reprogramming. Improved Results With TNT Method Dr. Daniel Poppe, a cell biologist from UWA, the Harry Perkins Institute, and co-first author, said the iPS cells generated using the TNT method differentiated into many other cells, such as neuron progenitors, better than the iPS cells generated with the standard method. Monash University student and co-first author Jia Tan said the team’s TNT method was dynamite. “It solves problems associated with conventionally generated iPS cells that if not addressed could have severely detrimental consequences for cell therapies in the long run,” he said. Future Implications and Research Professor Polo said that despite their breakthrough, the precise molecular mechanisms underlying the iPS epigenome aberrations and their correction are not fully known. Further research is needed to understand them. “We predict that TNT reprogramming will establish a new benchmark for cell therapies and biomedical research, and substantially advance their progress,” Professor Lister said. Reference: “Transient naive reprogramming corrects hiPS cells functionally and epigenetically” by Sam Buckberry, Xiaodong Liu, Daniel Poppe, Jia Ping Tan, Guizhi Sun, Joseph Chen, Trung Viet Nguyen, Alex de Mendoza, Jahnvi Pflueger, Thomas Frazer, Dulce B. Vargas-Landín, Jacob M. Paynter, Nathan Smits, Ning Liu, John F. Ouyang, Fernando J. Rossello, Hun S. Chy, Owen J. L. Rackham, Andrew L. Laslett, James Breen, Geoffrey J. Faulkner, Christian M. Nefzger, Jose M. Polo and Ryan Lister, 16 August 2023, Nature. DOI: 10.1038/s41586-023-06424-7 The collaborative research project also included researchers from the Australian National University, Westlake University, Queen Mary University of London, Mater Research Institute, University of Queensland, Queensland Brain Institute, South Australian Health & Medical Research Institute, Duke-NUS Medical School, and CSIRO.

Prof. Magdalena Osburn removes a sample during a site visit in August. Credit: Sanford Underground Research Facility A former goldmine serves as a gateway to explore microbial life deep within the Earth’s crust. If you totaled the mass of all microbes dwelling beneath the Earth’s surface, their combined biomass would surpass that of all life in our oceans. However, due to the challenge of accessing these depths, this teeming underground life remains largely unexplored and poorly understood. Utilizing a repurposed goldmine in South Dakota’s Black Hills as a laboratory, researchers from Northwestern University have crafted the most comprehensive map yet of these elusive and unusual microbes beneath our feet. In total, the researchers characterized nearly 600 microbial genomes — some of which are new to science. Out of this batch, Northwestern geoscientist Magdalena Osburn, who led the study, says most microbes fit into one of two categories: “minimalists,” which have streamlined their lives by eating the same thing all day, every day; and “maximalists,” which are ready and prepared to greedily grab any resource that might come their way. The study was recently published in the journal Environmental Microbiology. An exterior view of the former goldmine, which is now the Sanford Underground Research Facility. Credit: Sanford Underground Research Facility Not only does the new study expand our knowledge of the microbes living deep within the subsurface, it also hints at potential life we someday might find on Mars. Because the microbes live on resources found within rocks and water that are physically separate from the surface, these organisms also potentially could survive buried within Mars’ dusty red depths. “The deep subsurface biosphere is enormous; it’s just a vast amount of space,” said Osburn, an associate professor of Earth and planetary science at Northwestern’s Weinberg College of Arts and Sciences. “We used the mine as a conduit to access that biosphere, which is difficult to reach no matter how you approach it. The power of our study is that we ended up with a lot of genomes, and many from understudied groups. From that DNA, we can understand which organisms live underground and learn what they could be doing. These are organisms that we often can’t grow in the lab or study in more traditional contexts. They are often called ‘microbial dark matter’ because we know so little about them.” A portal into the Earth’s crust For the past 10 years, Osburn and her students have regularly visited the former Homestake Mine in Lead, South Dakota, to collect geochemical and microbial samples. Now called the Sanford Underground Research Facility (SURF), the deep underground laboratory hosts a number of research experiments across a range of disciplines. In 2015, Osburn established six experimental sites, collectively called the Deep Mine Microbial Observatory, throughout SURF. “The mine is now a facility dedicated to underground science,” Osburn said. “Researchers mostly perform high-energy particle physics experiments. But they also let us study the deep biospheres that live within the rocks. We can set up experiments in a controlled, dedicated site and check on them months later, which we would not be able to do in an active mine.” By boring holes into rocks inside the mine, Osburn and her team capture fracture fluids, composed of water and dissolved gases. Some of these fluids are up to 10,000 years old and are teeming with microbial life that is otherwise isolated and ignored. In the new study, Osburn and her team collected eight fluid samples, gathered at various points throughout the mine — spanning depths from the surface all the way to about 1.5 kilometers deep. The range of samples provides a window into a gradient of microbial life with depth. Minimalists v. maximalists Back in Osburn’s lab at Northwestern, she and her team sequenced the microbial DNA held within the samples. Of the nearly 600 genomes characterized, microbes represented 50 distinct phyla and 18 candidate phyla. Out of this diverse community of microbes, Osburn discovered that, at some point, each lineage gravitates to a life-defining trajectory: become a minimalist or a maximalist. “Man of the microbes we found were either minimalists: ultra-streamlined with one job that it does very well alongside a close consortium of collaborators, or it can do a little bit of everything,” Osburn said. “These maximalists are ready for every resource that comes along. If there is an opportunity to make some energy or transform a biomolecule, it is prepared. By looking at its genome, we can tell it has many options. If nutrients are scarce, it can just make its own.” Prof. Magdalena Osburn collects fracture fluids, composed of water and dissolved gases. Credit: Sanford Underground Research Facility The minimalists, Osburn explained, typically share resources with friends, which also have specialized jobs. “Some of these lineages don’t even have genes to make their own lipids, which blows my mind,” Osburn said. “Because how can you make a cell without lipids? It’s sort of like how humans can’t make every amino acid, so we eat protein to get the amino acids that we cannot make on our own. But this is on a more extreme scale. The minimalists are extreme specialists, and all together, they make it work. It’s a lot of sharing and no duplication of effort.” Insights on Earth and beyond As we imagine life beyond our Earth, Osburn said these underground microbes might provide clues for what potentially could be living elsewhere. “I get really excited when I see evidence of microbial life, doing its thing without us, without plants, without oxygen, without surface atmosphere,” she said. “These kinds of life very well could exist deep within Mars or in the oceans of icy moons right now. The forms of life tell us about what might live elsewhere in the solar system.” And, they have implications for our own planet. As the industry looks for locations for long-term carbon storage, for example, many companies are exploring the possibilities for injecting carbon dioxide deep into the ground. As we explore those options, Osburn reminds us not to forget the microbes. “We need to be cognizant of life in the deep subsurface and how human activity, like mining and carbon storage, could affect it,” she said. “If we store carbon dioxide underground, there are microbes that could metabolize it to make methane, for example. There is a biosphere underground that, depending on how it’s perturbed, has the potential to affect the surface.” Reference: “A metagenomic view of novel microbial and metabolic diversity found within the deep terrestrial biosphere at DeMMO: A microbial observatory in South Dakota, USA” by Lily Momper, Caitlin P. Casar and Magdalena R. Osburn, 14 November 2023, Environmental Microbiology. DOI: 10.1111/1462-2920.16543 The study was supported by NASA Exobiology (grant numbers NNH14ZDA001N, NNX15AM086), the David and Lucile Packard Foundation and the Canadian Institute for the Advancement of Research — Earth 4D.

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