Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Taiwan pillow ODM development service

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Insole ODM factory in Indonesia

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Customized sports insole ODM China

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.High-performance insole OEM Vietnam

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.China OEM/ODM hybrid insole services

A new study shows that brain connectivity undergoes a dramatic reorganization at birth, with regional differences and critical roles for networks like the subcortical hub. This research highlights key aspects of early development and its potential links to environmental factors. New research explores the developmental trajectory of global functional neural networks before and after birth. A study recently published in the journal PLOS Biology, led by Lanxin Ji and Moriah Thomason from New York University School of Medicine, reveals that brain-imaging data from fetuses and infants shows a rapid increase in functional connectivity between brain regions on a global scale at birth. This surge may reflect neural processes that enable the brain to adapt to the external environment. Understanding the sequence and timing of brain functional network development at the beginning of human life is critical. Yet many questions remain regarding how human brain functional networks emerge and develop during the birth transition. To fill this knowledge gap, Thomason and colleagues leveraged a large functional magnetic resonance imaging dataset to model developmental trajectories of brain functional networks spanning 25 to 55 weeks of post-conceptual gestational age. The final sample included 126 fetal scans and 58 infant scans from 140 subjects. Regional Differences in Brain Connectivity The researchers observed distinct growth patterns in different regions, showing that neural changes accompanying the birth transition are not uniform across the brain. Some areas exhibited minimal changes in resting-state functional connectivity (RSFC) — correlations between blood oxygen level-dependent signals between brain regions when no explicit task is being performed. But other areas showed dramatic changes in RSFC at birth. The subcortical network, sensorimotor network, and superior frontal network stand out as regions that undergo rapid reorganization during this developmental stage. Subcortical Network as a Communication Hub Additional analysis highlighted the subcortical network as the only region that exhibited a significant increase in communication efficiency within neighboring nodes. The subcortical network represents a central hub, relaying nearly all incoming and outgoing information to and from the cortex and mediating communication between cortical areas. On the other hand, there was a gradual increase in global efficiency in sensorimotor and parietal-frontal regions throughout the fetal to neonatal period, possibly reflecting the establishment or strengthening of connections as well as the elimination of redundant connections. According to the authors, this work unveils fundamental aspects of early brain development and lays the foundation for future research on the influence of environmental factors on this process. In particular, further studies could reveal how factors such as sex, prematurity, and prenatal adversity interact with the timing and growth patterns of children’s brain network development. The authors add, “This study for the first time documents the significant change of brain functional networks over the birth transition. We observe that growth patterns are regionally specific, with some areas of the functional connectome showing minimal changes, while others exhibit a dramatic increase at birth.” Reference: “Trajectories of human brain functional connectome maturation across the birth transition” by Lanxin Ji, Iris Menu, Amyn Majbri, Tanya Bhatia, Christopher J. Trentacosta and Moriah E. Thomason, 19 November 2024, PLOS Biology. DOI: 10.1371/journal.pbio.3002909

Pseudomonas bacteria deploy their nano-spearguns when damaged by a sharp tip (15,000 x magnification). Credit: University of Basel, Biozentrum/SNI Nano Imaging Lab Researchers found that Pseudomonas aeruginosa bacteria rapidly assemble their T6SS nanoweapons in response to outer membrane damage, enabling precise retaliation against competitors.​ Some bacteria deploy tiny spearguns to retaliate against rival attacks. Researchers at the University of Basel simulated these attacks by poking bacteria with an ultra-sharp tip. Through this approach, they discovered that bacteria assemble their nanoweapons in response to cell envelope damage and rapidly strike back with high precision. In the microbial world, peaceful coexistence coexists with fierce competition for nutrients and space. Certain bacteria outcompete rivals and defend against attackers by injecting them with a lethal cocktail using tiny, nano-sized spearguns known as type VI secretion systems (T6SS). Bacteria respond to cell envelope damage The research group led by Professor Marek Basler at the Biozentrum, University of Basel, has been studying the T6SS of different bacterial species for many years. “We knew that Pseudomonas aeruginosa uses its T6SS to fire back when attacked”, explains Basler. “But we did not know what exactly triggers the assembly of the nano-speargun: the contact with neighbors, toxic molecules, or simply cell damage?” In close collaboration with Roderick Lim, Argovia Professor for Nanobiology at the Biozentrum and the Swiss Nanoscience Institute (SNI), the researchers have now demonstrated: Pseudomonas aeruginosa responds to ruptures in the outer membrane – initiated by mechanical force, such as poking with a sharp tip. The study has been published in Science Advances. Puncturing bacterial envelope with a tiny “needle” Roderick Lim’s lab has long-standing expertise in atomic force microscopy (AFM) technology. “Using AFM, we have been able to mimic a bacterial T6SS attack,” says Mitchell Brüderlin, PhD student at the SNI PhD School and first author of the study. “With the needle-like, ultra-sharp AFM tip, we can touch the bacterial surface and, with gradually increasing the pressure, puncture the outer and the inner membrane in a controlled manner.” In combination with fluorescence microscopy, the researchers revealed that the bacteria respond to outer membrane damage. “Within ten seconds the bacteria assemble their T6SS, often repeatedly, at the site of damage and fire back with pinpoint accuracy,” adds Basler. “Our work clearly shows that breaking the outer membrane is necessary and sufficient to trigger T6SS assembly.” New insights into bacterial defense mechanisms The biggest challenge for the researchers was the size and the shape of the bacteria. “So far, we have only used the AFM to study eukaryotic cells, including human cells,” explains Lim. “But Pseudomonas bacteria are more than ten times smaller than human cells, so it was demanding to poke them at a specific site.” In the microbial ecosystem, survival is all about strategy, and Pseudomonas aeruginosa has certainly mastered the art of defense. “The targeted and swift retaliation against local attacks minimizes misfiring and optimizes the cost-benefit ratio”, says Basler. This clever tactic gives Pseudomonas a survival advantage, enabling it to incapacitate attackers and thrive in diverse and often challenging environments. Reference: “Pseudomonas aeruginosa assembles H1-T6SS in response to physical and chemical damage of the outer membrane” by Mitchell Brüderlin, Maxim Kolesnikov, Florian Röthlin, Roderick Y. H. Lim and Marek Basler, 5 March 2025, Science Advances. DOI: 10.1126/sciadv.adr1713

Researchers from the University of Rochester have discovered that blinking does more than keep our eyes moist; it also enhances visual processing by altering the light patterns received by the retina, thereby providing a different kind of visual signal that helps our brain perceive the big picture more effectively. This finding challenges the traditional view of vision, suggesting it involves not just sensory input but also motor activity, similar to other senses. Researchers discover that blinking is crucial for processing visual information, challenging traditional perspectives on vision and contributing to a broader revision of understanding in the field. The simple act of blinking occupies a surprisingly large portion of our time awake. On average, humans spend about 3 to 8 percent of their waking hours with their eyes closed due to blinking. Given that blinks prevent an image of the external scene from forming on the retina, it’s a peculiar quirk of evolution that we spend so much time in this seemingly vulnerable state—especially considering that eye blinks occur more frequently than necessary just to keep our eyes well lubricated. So why is blinking important? Researchers from the University of Rochester investigated the curious case of blinking and found that eye blinks aren’t just a mechanism to keep our eyes moist; blinks also play an important role in allowing our brains to process visual information. The researchers published their findings in the Proceedings of the National Academy of Sciences. “By modulating the visual input to the retina, blinks effectively reformat visual information, yielding luminance signals that differ drastically from those normally experienced when we look at a point in the scene,” says Michele Rucci, a professor in the Department of Brain and Cognitive Sciences. The big picture—in the blink of an eye Rucci and his colleagues tracked eye movements in human observers and combined this data with computer models and spectral analysis—analyzing the various frequencies in visual stimuli—to study how blinking affects what the eyes see compared to when the eyelids are closed. The researchers measured how sensitive humans are at perceiving different types of stimuli, such as patterns at different levels of details. They found that when people blink, they become better at noticing big, gradually changing patterns. That is, blinking provides information to the brain about the overall big picture of a visual scene. The results show that when we blink, the rapid motion of the eyelid alters the light patterns that are effective in stimulating the retina. This creates a different kind of visual signal for our brain compared to when our eyes are open and focused on a specific point. “We show that human observers benefit from blink transients as predicted from the information conveyed by these transients,” says Bin Yang, a graduate student in Rucci’s lab and the first author of the paper. “Thus, contrary to common assumption, blinks improve—rather than disrupt—visual processing, amply compensating for the loss in stimulus exposure.” Revising a view of vision The findings further reinforce the growing body of research in visual perception from Rucci’s laboratory, highlighting that how humans see is a combination of sensory input and motor activity. When we smell or touch, for instance, our body movements help our brain understand space. Researchers previously believed seeing was different, but Rucci’s research lends support to the idea that vision is more like the other senses. “Since spatial information is explicit in the image on the retina, visual perception was believed to differ,” Rucci says. “Our results suggest that this view is incomplete and that vision resembles other sensory modalities more than commonly assumed.” Reference: “Eye blinks as a visual processing stage” by Bin Yang, Janis Intoy and Michele Rucci, 2 April 2024, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2310291121 The study was funded by the National Institutes of Health.

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