Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw

Thailand insole ODM service provider

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.One-stop OEM/ODM solution provider Vietnam

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Thailand insole OEM manufacturer

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Soft-touch pillow OEM manufacturing factory in Taiwan

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Cushion insole OEM manufacturing facility Taiwan

A species of crayfish thought to be extinct was found in Shelta Cave, where Dr. Matthew L. Niemiller is snorkeling (shown above). Credit: Amata Hinkle A cave inside Huntsville’s city was discovered to contain a small, rare crayfish that was previously believed to be extinct. A team led by an assistant professor at The University of Alabama in Huntsville (UAH) has uncovered a small, rare crayfish that was believed to have been extinct for 30 years in a cave in the City of Huntsville in northern Alabama. Crayfish are a type of freshwater crustaceans that look similar to small lobsters. The Shelta Cave Crayfish, scientifically known as Orconectes sheltae, was discovered by Dr. Matthew L. Niemiller’s team during 2019 and 2020 trips into Shelta Cave, its sole habitat. A study on the discoveries was published in the journal Subterranean Biology. The study was co-authored by Dr. Niemiller, an assistant professor of biological sciences at UAH, a member of the University of Alabama System. Authors include Nathaniel Sturm of the University of Alabama, Katherine E. Dooley, K. Denise Kendall Niemiller of UAH, and Dr. Niemiller. A 2,500-foot (760-meter) cave system that is owned and maintained by the National Speleological Society (NSS) is the crayfish’s home. It is discretely tucked under the NSS’s national headquarters in northwest Huntsville, and it is surrounded by busy roads. The Shelta Cave Crayfish is known to exist only in Shelta Cave. Credit: Dr. Matthew L. Niemiller “The crayfish is only a couple of inches long with diminutive pincers that are called chelae,” Dr. Niemiller says. “Interestingly, the crayfish has been known to cave biologists since the early 1960s but was not formally described until 1997 by the late Dr. John Cooper and his wife Martha.” Dr. Cooper, a biologist and speleologist who was a member of the NSS, studied the aquatic life in Shelta Cave with a particular focus on crayfish for his dissertation work in the late 1960s and early 1970s. Shelta Cave’s aquatic ecosystem was particularly diverse then, with at least 12 cave-dependent species documented, including three species of cave crayfishes. “No other cave system to date in the U.S. has more documented cave crayfishes co-occurring with each other,” Dr. Niemiller says. Collapse of Shelta Cave’s Aquatic Ecosystem But the aquatic ecosystem, including the Shelta Cave Crayfish, crashed sometime in the early 1970s. The crash may be related to a gate that was built to keep people out of the cave and yet still allows a grey bat maternity population to move freely in and out. “The initial design of the gate was not bat-friendly, and the bats ultimately vacated the cave system,” Dr. Niemiller says. “Coupled with groundwater pollution and perhaps other stressors, that all may have led to a perfect storm resulting in the collapse of the aquatic cave ecosystem.” Even before the decline in the aquatic cave community, the Shelta Cave Crayfish was never common compared to the other two species, Southern Cave Crayfish (Orconectes australis) and Alabama Cave Crayfish (Cambarus jonesi). “To the best of our knowledge, only 115 individuals had been confirmed from 1963 through 1975. Since then, only three have been confirmed – one in 1988 and the two individuals we report in 2019 and 2020,” Dr. Niemiller says. “After a couple of decades of no confirmed sightings and the documented dramatic decline of other aquatic cave life at Shelta Cave, it was feared by some, including myself, that the crayfish might now be extinct.” Rediscovery and Conservation Efforts While it’s encouraging that the Shelta Cave Crayfish still persists, he says scientists still haven’t rediscovered other aquatic species that once lived in the cave system, such as the Alabama Cave Shrimp and Tennessee Cave Salamander. “The groundwater level in Shelta Cave is the result of water that works its way naturally through the rock layers above the cave – called epikarst – from the surface,” says Dr. Niemiller. “However, urbanization in the area above the cave system may have altered rates at which water infiltrates into the cave and also increased rates of pollutants, such as pesticides and heavy metals entering the cave system.” The crayfish was rediscovered during an aquatic survey aimed at documenting all life that was encountered in the cave system. “I really wasn’t expecting to find the Shelta Cave Crayfish. My students, colleagues, and I had visited the cave on several occasions already leading up to the May 2019 trip,” Dr. Niemiller says. “We would be fortunate to see just a couple of Southern Cavefish and Southern Cave Crayfish during a survey.” While snorkeling in about 15 feet of water in North Lake located in the Jones Hall section of the cave, Dr. Niemiller spotted a smaller-sized cave crayfish below him. “As I dove and got closer, I noticed that the chelae, or pincers, were quite thin and elongated compared to other crayfish we had seen in the cave,” he says. “I was fortunate to swoop up the crayfish with my net and returned to the bank.” It was a female, measuring under an inch in carapace length, and had developing ova internally, so it was a mature adult. “We noted some other morphological characters, took photographs, acquired a tissue sample, and released the crayfish,” Dr. Niemiller says. “The second Shelta Cave Crayfish that we encountered was in August 2020 in the West Lake area,” he says. The team had searched much of the area and didn’t see much aquatic life. As they started to make their way out the lake passage to return to the surface, Nate Sturm, a master’s student in biology at the University of Alabama who had accompanied the lab for the trip, noticed a small white crayfish in an area that the team had previously walked through. “It was a male with thin and elongated chelae,” Dr. Niemiller says. “I had already walked ahead of the area and did not see the crayfish. Thank goodness for young eyes!” DNA Analysis and Conservation Challenges To aid identification, the team analyzed short fragments of mitochondrial DNA in the tissue samples collected. “We compared the newly generated DNA sequences with sequences already available for other crayfish species in the region,” Dr. Niemiller says. “A challenge we faced was that no DNA sequences existed prior to our study for the Shelta Cave Crayfish, so it was a bit of a process of elimination, so to speak.” While few crayfish are considered single-site endemics, in other words, known to exist in just one location, that’s somewhat more common in cave-dwelling species like the Shelta Cave Crayfish, he says. “A couple other cave crayfishes are known from single cave systems in the United States. A challenge we face when trying to conserve such species is determining whether they really are known from a single cave system, or might they have slightly larger distributions but we are hampered by our ability to study life underground.” Predation and Dietary Behavior of Shelta Cave Crayfish Outside of the dissertation work done by Dr. Cooper, little about the life history and ecology of the species is known. “The Southern Cavefish (Typhlichthys subterraneus) and Tennessee Cave Salamander (Gyrinophilus palleucus) may be predators of smaller young of the Shelta Cave Crayfish. Larger Southern Cave Crayfish and Alabama Cave Crayfish might also feed on small young,” Dr. Niemiller says. “We know nothing of the diet of the species, but it likely is an omnivore feeding on organic matter washed or brought into the cave, as well as small invertebrates such as copepods and amphipods.” Although this research occurred prior to the grant, Dr. Niemiller is currently conducting the first-ever comprehensive assessment of groundwater biodiversity in the central and eastern United States, a pioneering search for new species and a new understanding of the complex web of life that exists right under our feet. The research is funded by a five-year, $1.029 million National Science Foundation (NSF) CAREER award. He says knowing the health of populations of the tiny creatures that are dependent on groundwater is important. “Groundwater is critically important not just for the organisms that live in groundwater ecosystems, but for human society for drinking water, agriculture, etc.,” Dr. Niemiller says. “The organisms that live in groundwater provide important benefits, such as water purification and biodegradation,” he says. “They also can act like ‘canaries in the coal mine,’ indicators of overall groundwater and ecosystem health.” Reference: “Rediscovery and phylogenetic analysis of the Shelta Cave Crayfish (Orconectes sheltae Cooper & Cooper, 1997), a decapod (Decapoda, Cambaridae) endemic to Shelta Cave in northern Alabama, USA” by Katherine E. Dooley, K. Denise Kendall Niemiller, Nathaniel Sturm and Matthew L. Niemiller, 20 May 2022, Subterranean Biology. DOI: 10.3897/subtbiol.43.79993

Schematic of gravity machine — a rotating microscope that enables a virtual reality arena for plankton and marine snow. The tool enables an infinite field of view microscope in the Z-axis, enabling observation of a sedimenting particle over long periods of time. Credit: Rebecca Konte, PrakashLab, Stanford Stanford researchers have discovered that microscopic marine organisms produce mucus “parachutes” that slow their descent, impacting how effectively oceans sequester carbon. This finding, which contradicts previous assumptions about ocean carbon sinks, suggests that models of carbon sequestration might need revising. New Insights Into Ocean Carbon Sequestration New Stanford-led research reveals a hidden factor that could revolutionize our understanding of how oceans mitigate climate change. Published today (October 10) in the journal Science, the study exposes previously unseen mucus “parachutes” produced by microscopic marine organisms that significantly slow their descent. This puts the brakes on a crucial process for removing carbon dioxide from the atmosphere. The surprising findings suggest that previous estimates of the ocean’s carbon sequestration potential might have been too high, yet they also pave the way for refining climate models and guiding policymakers in their climate mitigation strategies. “We haven’t been looking the right way,” said study senior author Manu Prakash, an associate professor of bioengineering and of oceans in the Stanford School of Engineering and Stanford Doerr School of Sustainability. “What we found underscores the importance of fundamental scientific observation and the need to study natural processes in their true environments. It’s critical to our ability to mitigate climate change.” Video of marine snow sinking in an infinite water column generated by gravity machine. The sinking marine snow interacts with a wide variety of plankton as it travels through the vertical column. Credit: PrakashLab, Stanford Unveiling the Biological Pump Marine snow – a mixture of dead phytoplankton, bacteria, fecal pellets, and other organic particles – absorbs about a third of human-made carbon dioxide from the atmosphere and shuttles it down to the ocean floor where it is locked away for millennia. Scientists have known about this phenomenon – known as the biological pump – for some time. However, the exact manner in which these delicate particles fall (the ocean’s average depth is 4 kilometers, or 2.5 miles) has remained a mystery until now. The researchers unlocked the mystery using an unusual invention – a rotating microscope developed in Prakash’s lab that flips the problem on its head. The device moves as organisms move within it, simulating vertical travel over infinite distances and adjusting aspects such as temperature, light, and pressure to emulate specific ocean conditions. Marine snow sedimentation with flow field. Artistic rending of real imaging data collected across the Gulf of Maine using a rotating microscope. Credit: PrakashLab, Stanford Observing Marine Snow in Natural Settings Over the past five years, Prakash and his lab members have brought their custom-built microscopes on research vessels to all the world’s major oceans – from the Arctic to Antarctica. On a recent expedition to the Gulf of Maine, they collected marine snow by hanging traps in the water, then rapidly analyzed the particles’ sinking process in their rotating microscope. Since marine snow is a living ecosystem, it is important to make these measurements at sea. The rotating microscope allowed the team to observe marine snow in its natural environment in exquisite detail – instead of a distant lab – for the first time. The results stunned the researchers. They revealed that marine snow sometimes creates parachute-like mucus structures that effectively double the time the organisms linger in the upper 100 meters of the ocean. This prolonged suspension increases the likelihood of other microbes breaking down the organic carbon within the marine snow particles and converting it back into readily available organic carbon for other plankton – stalling carbon dioxide absorption from the atmosphere. Beauty and Complexity in the Smallest Details The researchers point to their work as an example of observation-driven research, essential to understanding how even the smallest biological and physical processes work within natural systems. “Theory tells you how a flow around a small particle looks like, but what we saw on the boat was dramatically different,” said study lead author Rahul Chajwa, a postdoctoral scholar in the Prakash Lab. “We are at the beginning of understanding these complex dynamics.” This work lays out an important fact. For the last 200 years, scientists have studied life, including plankton, in a two-dimensional plane, trapped in small cover slips under a microscope. On the other hand, doing microscopy at high resolution is very hard on the high seas. Chajwa and Prakash emphasize the importance of leaving the lab and conducting scientific measurements as close as possible to the environment in which they occur. Implications and Future Directions Supporting research that prioritizes observation in natural environments should be a priority for public and private organizations that fund science, the researchers argue. “We cannot even ask the fundamental question of what life does without emulating the environment that it evolved with,” Prakash said. “In biology, stripping it away from its environment has stripped away any of our capacity to ask the right questions.” Beyond its importance in directly measuring marine carbon sequestration, the study also reveals the beauty in everyday phenomena. Much like sugar dissolving in coffee, marine snow’s descent into the depth of the ocean is a complex process influenced by factors we don’t always see or appreciate. “We take for granted certain phenomena, but the simplest set of ideas can have profound effects,” Prakash said. “Observing these details – like the mucus tails of marine snow – opens new doors to understanding the fundamental principles of our world.” The researchers are working to refine their models, integrate the datasets into Earth-scale models, and release an open dataset from the six global expeditions they have conducted so far. This will be the world’s largest dataset of direct marine snow sedimentation measurements. They also aim to explore factors that influence mucus production, such as environmental stressors or the presence of certain species of bacteria. Although the researchers’ discovery is a significant jolt to how scientists have thought about tipping points in ocean-based sequestration, Prakash and his colleagues remain hopeful. On a recent expedition off the coast of Northern California, they discovered processes that can potentially speed up carbon sequestration. “Every time I observe the world of plankton via our tools, I learn something new,” Prakash said. Reference: “Hidden comet tails of marine snow impede ocean-based carbon sequestration” by Rahul Chajwa, Eliott Flaum, Kay D. Bidle, Benjamin Van Mooy and Manu Prakash, 11 October 2024, Science. DOI: 10.1126/science.adl5767 Prakash is an associate professor of bioengineering in the Stanford Schools of Engineering and Medicine; associate professor, by courtesy, of biology in the Stanford School of Humanities and Sciences; associate professor, by courtesy, of oceans in the Stanford Doerr School of Sustainability; senior fellow at the Stanford Woods Institute for the Environment; and member of Bio-X, the Maternal & Child Health Research Institute, and the Wu Tsai Neurosciences Institute. Co-authors of the study also include Eliott Flaum, a PhD student in biophysics in the Stanford School of Medicine at the time of the research, and researchers from Rutgers University and the Woods Hole Oceanographic Institution. This project was funded by the Big Ideas for Oceans program of the Stanford Doerr School of Sustainability’s Oceans Department and the Stanford Woods Institute for the Environment, the Schmidt Foundation Innovation Fellows Program, the National Science Foundation, the Human Frontier Science Program, and Dalio Philanthropies.

Johns Hopkins Medicine researchers have discovered that certain retinal photoreceptors employ two signaling pathways simultaneously for vision signal transmission, suggesting ancient evolutionary origins. This finding provides new insights into the complex functioning of the mammalian eye and marks a significant advancement in the field of neuroscience. Neuroscientists at Johns Hopkins have demonstrated that specialized cells can signal the presence of light simultaneously in two distinct ways Working with mammalian retinal cells, neuroscientists at Johns Hopkins Medicine have shown that, unlike most light-sensing cells (photoreceptors) in the retina, one special type uses two different pathways at the same time to transmit electrical “vision” signals to the brain. The work also reveals that such photoreceptors, according to the researchers, may have ancient origins on the evolutionary scale. This and other findings, recently published in PNAS, “shed scientific as well as literal light” on a decades-long mystery about how such cells work, the researchers say. The new research was co-led by King-Wai Yau, Ph.D., professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine, and postdoctoral fellow Guang Li. King’s previous work led to advances in understanding how light-sensing cells in the mammalian eye transmit signals to the brain, findings that may eventually help scientists learn why people without sight can still sense light. In animals, including humans, photoreceptors (light-sensing cells) called rods and cones are located in the retina, a tissue layer at the back of the eye that responds to light. The rods and cones analyze visual signals that are transmitted via electrical signals to the brain, which interprets what is “seen.” Another type of photoreceptors in the retina, called intrinsically-photosensitive retinal ganglion cells (ipRGCs), use long protrusions (axons) that form the optic nerve to convey visual signals from rods and cones. The ipRGCs also perform other functions, such as setting the body’s light-driven circadian rhythms and distinguishing contrast and color. Dual Pathway Discovery It has been known that photoreceptors in animals detect light by using a signaling pathway named for the cell’s origin. Photoreceptors of “microvillous” origin, similar to those in the fruit fly eye, use the enzyme phospholipase C to signal light detection — whereas, photoreceptors of ciliary origin, such as those in our rods and cones, use a cyclic-nucleotide pathway. To signal light detection, most photoreceptors use either the microvillous or ciliary pathway, not both. However, in experiments to further understand how ipRGCs work, Yau’s team found that ipRGCs use both pathways at the same time. The researchers discovered this by exposing ipRGCs to brief pulses of bright light. In those conditions, the microvillous signaling pathway produces faster electrical responses and precedes, with some overlap, a slower response by the ciliary pathway. Yau’s team found that all six subtypes of ipRGCs use both microvillous and ciliary signaling mechanisms — although at different percentages — at the same time. The Johns Hopkins team also found that while most photoreceptors using the ciliary signaling pathway use a particular cyclic nucleotide, cGMP, as the signaling messenger, ipRGCs use another, cAMP, which is similar to jellyfish, an animal much older on the evolutionary scale. This suggests that ipRGCs may have an ancient origin. Reference: “Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs” by Guang Li, Lujing Chen, Zheng Jiang and King-Wai Yau, 18 December 2023, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2315282120 Other Johns Hopkins researchers who contributed to this study are Lujing Chen and Zheng Jiang. This study was funded by a grant from the National Institutes of Health (R01 EY014596) and a Beckman-Argyros Award in Vision Research.

DVDV1551RTWW78V