Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Vietnam graphene sports insole ODM

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Indonesia sustainable material ODM solutions

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.China eco-friendly graphene material processing

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Innovative insole ODM solutions in Indonesia

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Graphene-infused pillow ODM Vietnam

Vertebrate evolution timeline. Credit: Dr. Guojie Zhang A new study reveals that the genetic basis for limbs and lungs predates the vertebrate land transition by 50 million years, reshaping our understanding of human evolutionary history. People traditionally think that lungs and limbs are key innovations that came with the vertebrate transition from water to land. But in fact, the genetic basis of air-breathing and limb movement was already established in our fish ancestor 50 million years earlier. This, according to a recent genome mapping of primitive fish conducted by the University of Copenhagen, among others. The new study changes our understanding of a key milestone in our own evolutionary history. There is nothing new about humans and all other vertebrates having evolved from fish. The conventional understanding has been that certain fish shimmied landwards roughly 370 million years ago as primitive, lizard-like animals known as tetrapods. According to this understanding, our fish ancestors came out from water to land by converting their fins to limbs and breathing under water to air-breathing. However, limbs and lungs are not innovations that appeared as recent as once believed. Our common fish ancestor that lived 50 million years before the tetrapod first came ashore already carried the genetic codes for limb-like forms and air breathing needed for landing. These genetic codes are still present in humans and a group of primitive fishes. This has been demonstrated by recent genomic research conducted by University of Copenhagen and its partners. The new research reports that the evolution of these ancestral genetic codes might have contributed to the vertebrate water-to-land transition, which changes the traditional view of the sequence and timeline of this big evolutionary jump. The study has been published in the scientific journal Cell. “The water-to-land transition is a major milestone in our evolutionary history. The key to understanding how this transition happened is to reveal when and how the lungs and limbs evolved. We are now able to demonstrate that the genetic basis underlying these biological functions occurred much earlier before the first animals came ashore,” stated professor and lead author Guojie Zhang, from Villum Centre for Biodiversity Genomics, at the University of Copenhagen’s Department of Biology. A group of ancient living fishes might hold the key to explaining how the tetrapod ultimately could grow limbs and breathe in air. The group of fish includes the bichir that lives in shallow freshwater habitats in Africa. These fishes differ from most other extant bony fishes by carrying traits that our early fish ancestors might have had over 420 million years ago. And the same traits are also present in, for example, humans. Through genomic sequencing, the researchers found that the genes needed for the development of lungs and limbs have already appeared in these primitive species. Our Synovial Joint Evolved From Fish Ancestor Using pectoral fins with a locomotor function like limbs, the bichir can move about on land in a similar way to the tetrapod. Researchers have for some years believed that pectoral fins in bichir represent the fins that our early fish ancestors had. The new genome mapping shows that the joint which connects the socalled metapterygium bone with the radial bones in the pectoral fin in the bichir is homologous to synovial joints in humans — the joints that connect upper arm and forearm bones. The DNA sequence that controls the formation of our synovial joints already existed in the common ancestors of bonefish and is still present in these primitive fishes and in terrestrial vertebrates. At some point, this DNA sequence and the synovial joint was lost in all of the common bony fishes — the so-called teleosts. “This genetic code and the joint allows our bones move freely, which explains why the bichir can move around on land,” says Guojie Zhang. First Lungs, Then Swim Bladder Moreover, the bichir and a few other primitive fishes have a pair of lungs that anatomically resembles ours. The new study reveals that the lungs in both bichir and alligator gar also function in a similar manner and express same set of genes as human lungs. At the same time, the study demonstrates that the tissue of the lung and swim bladder of most extant fishes are very similar in gene expression, confirming they are homologous organs as predicted by Darwin. But while Darwin suggested that swim bladders converted to lungs, the study suggests it is more likely that swim bladders evolved from lungs. The research suggests that our early bony fish ancestors had primitive functional lungs. Through evolution, one branch of fish preserved the lung functions that are more adapted to air breathing and ultimately led to the evolution of tetrapods. The other branch of fishes modified the lung structure and evolved with swim bladders, leading to the evolution of teleosts. The swim bladders allow these fishes to maintain buoyancy and perceive pressure, thus better survive under water. “The study enlightens us with regards to where our body organs came from and how their functions are decoded in the genome. Thus, some of the functions related to lung and limbs did not evolve at the time when the water-to-land transition occurred, but are encoded by some ancient gene regulatory mechanisms that were already present in our fish ancestor far before landing. It is interesting that these genetic codes are still present in these ‘living-fossil” fishes, which offer us the opportunity to trace back the root of these genes,” concludes Guojie Zhang. FACT BOX 1: Not just limbs and lungs, but also the heart Primitive fish and humans also share a common and critical function in the cardio-respiratory system: The conus arteriosus, a structure in the right ventricle of our heart which might allow the heart to efficiently deliver the oxygen to the whole body, and which is also found in the bichir. However, the vast majority of bony fish have lost this structure. The researchers discovered a genetic element that appears to control the development of the conus arteriosus. Transgenic experiments with mice showed that when researchers removed this genetic element, the mutated mice died due to thinner, smaller right ventricles, which lead to congenital heart defects and compromised heart function. FACT BOX 2: The vast majority of extant fish species belong to the ray-finned fishes, a subclass of bony fish. These are typically fish with gills, fins and a swim bladder. The terrestrial group of vertebrates are known as tetrapod. The tetrapod includes all vertebrates that descended from the first animals adapted to a life on land by developing four limbs and lungs, i.e., all mammals, birds, reptiles and amphibians. The researchers’ theory is that the air-breathing ability in these primitive fishes allowed them to survive the second mass extinction roughly 375-360 million years ago. At that time, oxygen depletion in Earth’s oceans caused a majority of species to be wiped out. Lungs allowed some fish to survive on land. The study has been published in the scientific journal Cell. The research team also contributed to another paper which reported the genome for another primitive fish, the lungfish. The genome is the biggest vertebrate genome decoded so far. This paper was published in Cell at the same time. The research is supported by the Villum Foundation, among others. Reference: “Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes” by Xupeng Bi, Kun Wang, Liandong Yang, Hailin Pan, Haifeng Jiang, Qiwei Wei, Miaoquan Fang, Hao Yu, Chenglong Zhu, Yiran Cai, Yuming He, Xiaoni Gan, Honghui Zeng, Daqi Yu, Youan Zhu, Huifeng Jiang, Qiang Qiu, Huanming Yang, Yong E. Zhang, Wen Wang, Min Zhu, Shunping He and Guojie Zhang, 4 February 2021, Cell. DOI: 10.1016/j.cell.2021.01.046

Quercus robur was first introduced into South Africa in 1656. Today it is one of the most widespread and recognized trees in the South African landscape, such as the centuries-old oak trees lining the streets of Stellenbosch (also known as Eikestad or Oak City). But these centuries-old trees are also the most susceptible to infections and pests such as the polyphagous shot hole borer. Credit: Christiaan Gildenhuys The nearly 400-year-old history of oaks in South Africa may be coming to an end, forever changing the treescape of towns and cities such as Cape Town, George, Paarl, Stellenbosch, and Swellendam. In a research paper published in the South African Journal of Botany, ecologists from the Centre for Invasion Biology (CIB) at Stellenbosch University’s School for Climate Studies, traced the history of the introduction of the genus Quercus into South Africa, as well as its current status and the factors that are changing its distribution across our landscapes. Christiaan Gildenhuys, a postgraduate student in SU’s Department of Botany and Zoology and first author on the article, says the first written record of English oak (Quercus robur), dates to 1656, reportedly introduced under the authority of Jan van Riebeek himself: “Dozens of other oak species were introduced to the Cape of Good Hope by early Dutch settlers and the British colonial government. Many oaks were subsequently widely cultivated across the country and have since become one of the most widespread and recognized tree genera in South Africa today,” he explains. But now the species may have arrived at a crossroads. The Threat of Disease and Invasive Species Gildenhuys found that three oak species – English oak, Pin oak, and Cork oak – have become invasive along riverbanks and the urban-wildland interface in Stellenbosch and Cape Town. These oaks do not cause major problems as invaders now but may do so in the future. At the same time, many species (including the most widespread species, Q. robur or English oak) are highly susceptible to diseases and invasive beetles such as the polyphagous shot hole borer: “Not only does this mean that many century-old oaks are at risk, but it also means that infected trees must be removed before the infestation spreads further,” says Gildenhuys. The oak-lined streets of historical towns such as Stellenbosch in South Africa (the second oldest town in South Africa after Cape Town) are set to change over the next decade. These centuries-old oak trees are particularly susceptible to the onslaught of the Polyphagous shot hole borer. Credit: Christiaan Gildenhuys Prof. Dave Richardson, an ecologist at CIB and co-author, says the story of oaks in South Africa is a classic example of how global change is rapidly changing the roles and perspectives of species in urban areas. “We must accept that the potential impact of the polyphagous shot hole borer is a game changer. As a result of this invasion, the treescapes of many towns in South Africa are going to change rather radically. Landowners and authorities who may decide to replace infected Q. robur trees with less susceptible tree species must also consider the potential negative impacts of these species,” he explains The ideal would be to replace the infected trees with indigenous species which are less susceptible to pests and diseases such as the PSHB. However, people’s attachments to their oak-lined streets may inhibit replacement efforts and induce conflicts between management and stakeholders, he warns. Prof. Guy Midgley, interim director of the School for Climate Studies, says trees make a vital contribution to lessening the impact of climate change by reducing heat stress in urban areas. On the other hand, the way thousands of diseased trees are disposed of may significantly impact carbon emissions. Adding fuel to the fire is the debate about the cultural value of oaks in general. In one sector of South African society, these centuries-old trees are celebrated as part of our cultural heritage. In another sector, they are regarded as unwanted relics from a colonial past. Reference: “The genus Quercus (Fagaceae) in South Africa: Introduction history, current status, and invasion ecology” by Christiaan P. Gildenhuys, Luke J. Potgieter and David M. Richardson, 17 February 2024, South African Journal of Botany. DOI: 10.1016/j.sajb.2024.01.066 The study was funded by the Universiteit Stellenbosch and the Natural Sciences and Engineering Research Council of Canada.

Researchers have discovered a new deep-sea bacterial strain, Poriferisphaera hetertotrophicis, which is unique for its budding division model and plays a significant role in nitrogen assimilation. The bacteria also live symbiotically with a bacteriophage that further facilitates nitrogen metabolism. (Artist’s concept) Researchers have discovered a new species of marine bacteria that reproduces through a unique budding process and releases viruses to facilitate nitrogen metabolism. Researchers have isolated a new strain of marine bacteria with unique characteristics from the ocean seabed. The study, recently published in the journal eLife, is hailed by the editors as a significant contribution to our grasp of the physiological processes within deep-sea Planctomycetes bacteria. It highlights unique attributes, including its singular method of cell division, which sets it apart as the only known species in the class of Phycisphaerae bacteria that uses a distinct budding model of division. It provides what the editors also say is convincing evidence that the new species is extensively involved in nitrogen assimilation and lives with a chronic virus (bacteriophage) that facilitates nitrogen metabolism. Nitrogen cycling by bacteria is an essential process that frees up nitrogen for building into nucleic acids, amino acids, and proteins – the building blocks of life. “Until recently, most research on the Planctomycetes family of bacteria has focused on strains in freshwater and shallow ocean environments, because of the logistical difficulties associated with sampling and cultivating deep-sea strains,” says lead author Rikuan Zheng, a research associate at the Institute of Oceanology, Chinese Academy of Sciences, Beijing, China, and the National Laboratory for Marine Science and Technology, Qingdao, China. “Most Planctomycetes bacteria have been isolated using growth media that are nutritionally poor, so we wanted to see if using a nutrient-rich medium would make it possible to culture and further characterize members of this poorly understood family.” A novel bacteria, Poriferisphaera hetertotrophicis, observed using Transmission Electron Microscopy (TEM). Abbreviations: CM, outer membrane; Pi, cytoplasm; R, ribosome; N, nucleoid; ICM, cytoplasmic membrane; Py, peripla. Credit: Rikuan Zheng Isolation and Identification of Poriferisphaera hetertotrophicis To isolate the novel bacterium, the team took sediment samples from a deep-sea cold seep, where Planctomycetes bacteria are known to reside, and then encouraged their growth by supplementing a standard growth medium with the antibiotic rifampicin and sources of nitrogen. They cultured these enriched bacteria on agar and evaluated individual colonies further by gene sequencing. Among the bacteria, they identified a strain called ZRK32 that grew faster than others, and looked likely to be a member of the genus Poriferisphaera. To confirm this, the team compared the genetic similarities between this strain and other members of the Poriferisphaera genus and found that it was distinguishable from Poriferisphaera corsica, the only other species with a valid published name. This suggests that ZRK32 is a novel species – which the team proposes to call Poriferisphaera hetertotrophicis.  To learn more about this new species, the team studied its growth and how it multiplies. They found that, unlike other Planctomycetes family members, Poriferisphaera hetertotrophicis grows better in nutrient-rich media and multiplies via a budding mechanism, where parent cells create outgrowth buds that develop into daughter cells. Nitrogen Influences Growth and Viral Activation As the Planctomycetes bacteria family is known to play an important role in nitrogen cycling, the team next explored whether this was also the case for Poriferisphaera hetertotrophicis. To test this, they looked at the effects of different nitrogen-containing substances – nitrates, ammonia, and nitrogen dioxide – on Poriferisphaera hetertotrophicis growth. They found that adding nitrogen in the form of a nitrate or ammonia increased growth, whereas adding it as a nitrite inhibited growth. They also discovered that the addition of nitrate or ammonia caused the novel strain to release a bacteriophage – a type of virus that infects bacteria. Bacteriophages are widely distributed across oceans and can regulate nitrogen metabolism in their host bacteria. This bacteriophage – called phage-ZRK32 – was able to increase the growth of Poriferisphaera hetertotrophicis and other marine bacteria dramatically by facilitating nitrogen metabolism. Even though the team’s genetic analysis suggested Poriferisphaera hetertotrophicis contains all the necessary genes for metabolizing nitrate and ammonia, chronic infection with this bacteriophage may help to further optimize nitrogen metabolism. “Our analyses indicate that strain ZRK32 is a novel species, which grows best in nutrient-rich media and releases a bacteriophage in the presence of nitrogen,” concludes senior author Chaomin Sun, a Professor at the Institute of Oceanology, Chinese Academy of Sciences, and the National Laboratory for Marine Science and Technology. “This phage-ZRK32 is a chronic bacteriophage that lives within its host without killing it. Our findings provide a novel insight into nitrogen metabolism in Planctomycetes bacteria and a suitable model to study the interactions between Planctomycetes and viruses.” Reference: “Physiological and metabolic insights into the first cultured anaerobic representative of deep-sea Planctomycetes bacteria” by Rikuan Zheng, Chong Wang, Rui Liu, Ruining Cai and Chaomin Sun, 28 August 2023, eLife. DOI: 10.7554/eLife.89874.1

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