Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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One-stop OEM/ODM solution provider Indonesia

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Pillow ODM design company in Thailand

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Graphene-infused pillow ODM Indonesia

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Graphene sheet OEM supplier Taiwan

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Cushion insole OEM solution Indonesia

New research shows that sperm production is critical to how regions of the genome are re-organized within and between chromosomes during evolution. In particular, inherited chromosomal rearrangements are associated with physical and biochemical processes that are specific to the final stages of sperm production, after the meiotic cell divisions have completed. Researchers found that chromosomal rearrangements during sperm production play a key role in genome evolution, with male germ cells contributing more to these changes due to DNA compaction and repair processes. A study led by researchers at the Universitat Autònoma de Barcelona (UAB) and the University of Kent uncovers how the genome three-dimensional structure of male germ cells determines how genomes evolve over time. Published today (May 11, 2022) in Nature Communications and carried out in rodent species, these findings show that the distinctive events occurring during egg and sperm cell production have a different impact on genome evolution and open new research paths into the genetic origin of genome structure in all organisms. A comparison of genomes across many different mammalian species reveals that, while all species have a broadly similar catalog of genes, these are arranged in a different order for each species and can be turned off and on differently. These rearrangements may have an impact on gene function and regulation and, therefore, play a part in evolutionary changes and in defining species identity. Until now, the ultimate origin of these rearrangements has been a mystery: where (in which cell types) and when (during development) do they arise? Do they arise as a by-product of the normal reshuffling of genes between chromosome copies that occurs during meiosis, the cellular process to produce gametes (oocytes and sperm), or at some other stage in the life cycle? A genome is all of an organism’s genetic information. It is made up of DNA nucleotide sequences (or RNA in RNA viruses). The genome contains genes (coding regions) as well as noncoding DNA, mitochondrial DNA, and chloroplast DNA. The study of the genome is called genomics and is related to the fields of molecular biology and genetics. Now a research study led by scientists from the Universitat Autònoma de Barcelona (UAB) and the University of Kent shows that sperm production is key to how regions of the genome are re-organized within and between chromosomes during evolution. In particular, inherited chromosomal rearrangements are associated with physical and biochemical processes that are specific to the final stages of sperm production, after the meiotic cell divisions have been completed. Chromatin Remodeling and Genetic Recombination in Spermatogenesis The total sequence of DNA or genome of an individual is folded into a specifically tailored and dynamic 3D chromatin structure within the cell nuclei, that determines which genes are “turned on” and which are “turned off” in each cell type. Gametes are produced by all sexually reproducing organisms through a process called meiosis that involves one round of genome replication followed by two consecutive cell divisions, to leave haploid cells (gametes), carrying only one copy of each chromosome. During meiosis, genes are “shuffled” between the chromosome copies inherited from the mother and father, a process known as genetic recombination. These complex events imply that the genome must be packaged and unpackaged in a precise and highly regulated manner into chromatin. “Our work shows the dynamics of chromatin remodeling during the formation of male gametes is fundamental for understanding which parts of the genome are located close to each other inside the nucleus, and are therefore more likely to be involved in chromosomal rearrangements, in different moments throughout male spermatogenesis” throughout male spermatogenesis,” says Dr. Aurora Ruiz-Herrera, Associate Professor at the Department of Cell Biology, Physiology and Immunology of the Institute of Biotechnology and Biomedicine (IBB) at the UAB. Analyzing Genome Rearrangements in Rodents To study genome evolution, the team compared the genomes of 13 different rodent species and “unscrambled” the rearrangements that distinguish them. “This allowed us to work out the genome configuration of the rodent common ancestor and determine the locations of the evolutionary breakpoint regions (EBRs) participating in genome rearrangements,” explains Dr. Marta Farré, Lecturer in Genomics at the School of Biosciences in the University of Kent, and co-leader of the study. “Strikingly, EBRs were associated with regions that are active in later stages of spermatogenesis, when the developing male germ cells are called spermatids. Rearrangements occurring at EBRs were found to break and rejoin DNA stretches that are physically located close to each other in the spermatid nucleus,” says Dr. Peter Ellis, Senior Lecturer in Molecular Genetics and Reproduction at the School of Biosciences in the University of Kent and co-leader of the study. Furthermore, EBRs were not associated with meiotic recombination hotspots – indicating that these rearrangements most likely did not occur during meiosis in either males or females. Instead, EBRs were correlated with DNA damage locations in spermatids. Spermatids are cells undergoing the final stage of sperm development, after cell division has finished – and the events occurring during this process are male specific. This, therefore, carries the startling implication that males and females are not equal in terms of their impact on genome evolution. “Of all the rearrangements that distinguish a mouse from a rat, a squirrel, or a rabbit, the majority appear likely to have arisen in a sperm cell rather than an egg cell. For me, this shows that the male germline is the overall engine of genome structural evolution,” says Dr. Ellis. “We show that developing sperm cells retain a ‘memory’ of previous genome configurations. There are stretches of DNA that used to be part of a single chromosome in rodent common ancestor but are now located on different chromosomes in mouse – yet these still move close to each other and make physical contact specifically in developing sperm cells” says Dr. Marta Farré. Why in Male Germ Cells? The authors propose one explanation for their results is the different events that occur during egg and sperm cell production. While both sperm and egg cells reshuffle DNA during meiosis, the DNA breaks created during this process are repaired highly accurately. However, sperm cells also have to compact their DNA into a tiny volume to fit in the sperm head. This compaction causes DNA breaks and uses an error-prone method to repair the DNA. Some of these errors can generate genomic rearrangements – explaining why sperm development is a critical factor in genome evolution. On the other side, a current unsolved mystery is why some species have very stable genomes with few rearrangements, while others have highly dynamic genomes with multiple rearrangements. “Our work suggests that this may be due to the details of where and when DNA is broken and repaired during sperm production,” says Dr. Ruiz-Herrera. While the study was carried out in rodents, spermatogenesis is a highly conserved process and therefore this principle is likely to apply widely throughout the tree of life, researchers point out. Reference: “3D chromatin remodelling in the germ line modulates genome evolutionary plasticity” by Lucía Álvarez-González, Frances Burden, Dadakhalandar Doddamani, Roberto Malinverni, Emma Leach, Cristina Marín-García, Laia Marín-Gual, Albert Gubern, Covadonga Vara, Andreu Paytuví-Gallart, Marcus Buschbeck, Peter J. I. Ellis, Marta Farré and Aurora Ruiz-Herrera, 11 May 2022, Nature Communications. DOI: 10.1038/s41467-022-30296-6 Participating in this study led by the UAB and University of Kent were also the research teams from Josep Carreras Leukaemia Research Institute (IJC) and Sequentia Biotech.

The emergence of human diseases shares many challenges with species invasions, and studying them together could offer solutions. Invasions by alien insect and animal species have much in common with outbreaks of infectious diseases and could tell us a great deal about how pandemics spread, according to a research paper published today. Biological invasions, where animals, insects, plants, and microorganisms are transported around the globe by humans, are becoming more common and have a global annual cost of at least £118billion. An investigation by an international team of scientists, including the University of Leeds’ School of Biology, says the emergence of human diseases shares many of the same challenges as species invasions and that studying them together could provide solutions. Co-author of the report, Dr. Alison M. Dunn, a Professor of Ecology in the School of Biology, said: “Integrated approaches that take into account the health of humans and that of animals, plants, and the environment are urgently needed to prevent future pandemics and the spread of invasive species across the globe. “Cross-fertilization between the two disciplines could improve prediction, prevention, treatment, and mitigation of invasive species and infectious disease outbreaks, including pandemics, such as COVID-19.” The paper, which is published today in the journal, BioScience, says the prevention of species invasion requires analysis of how it will arrive into a new region (primary spread) and how it spreads to the surrounding region (secondary spread). But this dual pathway classification has seldom been used to look at emerging infectious organisms in humans — even though it is well known that factors such as behavior, income, tourism, and trade can influence transmission. Invasive insects are the most frequent transmitters of organisms causing human diseases. The tiger mosquito has spread to all inhabited continents through trade and has been responsible for the spread of dengue fever, yellow fever, West Nile virus, and chikungunya. Pathogens that cause these diseases go through the same stages as invasive species but can spread much more quickly, leading to pandemics, say the researchers. Even the patterns of spread of re-emerging “native” diseases, such as Ebola in West Africa, share similarities to those of invasive species. The paper concludes that biosecurity is key to preventing the spread of invasive species and of infectious diseases in humans and calls for medical scientists and ecologists to work together to learn more about both. Professor Montserrat Vilà, researcher at the Estación Biológica de Doñana and lead author of the study, said: “Pandemics such as COVID-19 and biological invasions have much in common. They are often linked by the same global change drivers, and they are showing similar features. This paper gives a detailed review of the parallels between scientific approaches to invasions and human epidemics. “Given increasing rates of emerging infectious pathogens and biological invasions worldwide and the ongoing global health crisis caused by coronavirus, the need for integrative and interdisciplinary approaches to biosecurity has never been greater.” Reference: “Viewing Emerging Human Infectious Epidemics through the Lens of Invasion Biology” by Montserrat VilÀ, Alison M Dunn, Franz Essl, Elena GÓmez-DÍaz, Philip E Hulme, Jonathan M Jeschke, MartÍn A NÚÑez, Richard S Ostfeld, AnÍbal Pauchard, Anthony Ricciardi and Belinda Gallardo, 19 May 2021, BioScience. DOI: 10.1093/biosci/biab047

Humpback whale song shares statistical structures with human language, highlighting unexpected similarities in communication across species. Credit: OperationCetaces A new study finds that humpback whale song shares statistical structures with human language, suggesting that cultural transmission plays a key role in shaping complex communication. Using methods inspired by infant speech learning, researchers identified recurring patterns in whale song, challenging assumptions about the uniqueness of human language and offering new perspectives on language evolution. Humpback whale song is a remarkable example of complex, culturally transmitted behavior. However, until now, there was little evidence to suggest it possesses a language-like structure. Human language, which is also passed down culturally, follows distinct statistical patterns in the frequency of recurring elements. In humans, these patterns facilitate learning and likely contribute to language transmission across generations. This study takes an innovative approach by applying methods inspired by how infants identify words in speech to analyze humpback whale recordings. The findings reveal that whale songs exhibit the same statistical structures present in all human languages. This discovery uncovers previously undetected patterns in whale song, highlighting a profound similarity between two otherwise unrelated species—both of whom rely on culturally transmitted communication systems. Spectrogram of whale song 2017 recording. Credit: OperationCetaces Whale song has a language-like structure Language has long been considered a uniquely human trait, with features that mark it out as distinct from the communication of all other species. However, research published in Science has uncovered the same statistical structure that is a hallmark of human language in humpback whale song. Humpback whale song is a striking example of a complex, culturally transmitted behavior, but up to now, there was little evidence it has language-like structure. Human language, which is also culturally transmitted, has recurring parts whose frequency of use follows a particular pattern. In humans, these properties help learning and may come about because they help language be passed from one generation to the next. This work innovatively applies methods inspired by how babies discover words in speech to humpback whale recordings, uncovering the same statistical structures found in all human languages. This work reveals previously undetected structure in whale song, illustrating a deep commonality between two unrelated species united by the fact that their communication systems are culturally transmitted. Humpback whale calf and mother. Credit: Marc-Quintin Led by Professor Inbal Arnon of the Hebrew University, Dr Ellen Garland of the University of St Andrews, and Professor Simon Kirby of the University of Edinburgh, in collaboration with Dr Claire Garrigue (IRD New Caledonia), Dr Jenny Allen (Griffith University), and Dr Emma Carroll (University of Auckland), this work represents a unique collaboration between linguists, developmental scientists, marine biologists, and behavioral ecologists. Humpback whale song is one of the most striking examples of a socially learned, culturally transmitted behavior in a nonhuman animal. Whale song exhibits systematic structure, however, until now, there was little evidence that this structure was like that of human language. One of the big challenges in studying non-human communication is finding out what the relevant parts of the system are. The authors’ breakthrough was to use insights from how babies discover words in speech, and apply them to eight years of humpback whale song data collected in New Caledonia. The authors found that whale song showed the same key statistical properties present in all known human languages. Implications for Language Evolution and Animal Communication They detected recurring parts whose frequency closely followed a particular skewed distribution, not previously found in any other non-human animal. This work reveals a deeply unexpected commonality between two unrelated species – humans and humpback whales – united by the fact that their communication system is culturally transmitted. This points to the crucial role of learning and transmission in the emergence of structure within such systems. Once thought of as the hallmark of human uniqueness, foundational aspects of human language may be shared across evolutionary distant species. Audio Playerhttps://scitechdaily.com/images/Whale-Song-2017-Recording.wav00:0000:0000:00Use Up/Down Arrow keys to increase or decrease volume. Dr Ellen Garland from the University of St Andrews said: “Revealing this hidden language-like structure in whale song was unexpected, but it strongly suggests this cultural behavior holds crucial insight into the evolution of complex communication across the animal kingdom.” “Whale song is not a language; it lacks semantic meaning. It may be more reminiscent of human music, which also has this statistical structure, but lacks the expressive meaning found in language.” “Whether the units we detected using the infant-inspired method are salient to the whales themselves remains an open question.” Prof Inbal Arnon from the Hebrew University said: “Using insights and methods from how babies learn language allowed us to discover previously undetected structure in whale song” “This work shows how learning and cultural transmission can shape the structure of communication systems: we may find similar statistical structure wherever complex sequential behavior is transmitted culturally.” “It raises the intriguing possibility that humpback whales, like human babies, may learn their song by tracking transitional probabilities between sound elements, and using dips in those probabilities as a cue to segment the song” Prof Simon Kirby from the University of Edinburgh said: “It suggests that our understanding of the evolution of language can benefit not only from looking at our closest primate relatives, but also at cases of convergent evolution elsewhere in nature.” “Looking beyond the way language is used to express meaning, we should consider how language is learned and transmitted culturally over multiple generations.” “These findings challenge long-held assumptions about the uniqueness of human language, uncovering deep commonalities between evolutionarily distant species.” Reference: “Whale song shows language-like statistical structure” by Inbal Arnon, Simon Kirby, Jenny A. Allen, Claire Garrigue, Emma L. Carroll and Ellen C. Garland, 6 February 2025, Science. DOI: 10.1126/science.adq7055

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