Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Pillow OEM for wellness brands China

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Taiwan OEM/ODM hybrid insole services

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Graphene cushion OEM factory in Thailand

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Graphene-infused pillow ODM factory Taiwan

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Breathable insole ODM development Thailand

A side-by-side comparison of Lacrymaria olor, a remarkable ciliate with its “neck” extended and retracted. Researchers discovered origami-like folds make this morphing possible where microtubules define folding pleats. Credit: Prakash Lab Stanford scientists have unveiled “lacrygami,” a phenomenon where Lacrymaria olor extends its structure dramatically, influenced by its cytoskeletal design, promising advances in microscopic technology. “There are some things in life you can watch and then never unwatch,” said Manu Prakash, associate professor of bioengineering at Stanford University, calling up a video of his latest fascination, the single-cell organism Lacrymaria olor, a free-living protist he stumbled upon playing with his paper Foldscope. “It’s … just … it’s mesmerizing.” “From the minute Manu showed it to me, I have just been transfixed by this cell,” said Eliott Flaum, a graduate student in the “curiosity-driven” Prakash Lab. Prakash and Flaum spent the last seven years studying Lacrymaria olor’s every move and recently published a paper on their work in the journal Science. Discovering Cellular Dynamics “The first time I came back with a fluorescence micrograph, it was just breathtaking,” Flaum said. “That image is in the paper.” The video Prakash queued up reveals why this organism is much more than a pretty picture: a single teardrop-shaped cell swims in a droplet of pond water. In an instant, a long, thin “neck” projects out from the bulbous lower end. And it keeps going. And going. Then, just as quickly, the neck retracts back, as if nothing had happened. In seconds, a cell that was just 40 microns tip-to-tail sprouted a neck that extended 1500 microns or more out into the world. It is the equivalent of a 6-foot human projecting its head more than 200 feet. All from a cell without a nervous system. “It is incredibly complex behavior,” Prakash said with a smile. Form Is Function L. olor is featured in the journal Science because Prakash and Flaum have discovered in this behavior a new geometric mechanism previously unknown in biology. And they are the first to explain how such a simple cell can produce such incredible morphodynamics, beautiful folding and unfolding – aka origami – at the scale of a single cell, time and again without fail. It is geometry. L. olor’s behavior is encoded in its cytoskeletal structure, just like human behavior is encoded in neural circuits. “This is the first example of cellular origami,” Prakash said. “We’re thinking of calling it lacrygami.” Specifically, it is a subset of traditional origami known as “curved-crease origami.” It is all based on a structure of thin, helical microtubules – ribs that wrap inside the cell’s membrane. These microtubule ribs are encased in a delicate diaphanous membrane, defining the crease pattern of peaks in a series of mountain-and-valley folds. Microstructural Insights and Mathematical Beauty Prakash and Flaum used transmission electron microscopy and other state-of-the-art investigatory techniques to show there are actually 15 of these stiff, helical microtubule ribbons enshrouding L. olor’s cell membrane – a cytoskeleton. These tubules coil and uncoil, leading to long projection and retraction, nesting back into themselves like the bellows of a compressed helical accordion. The gossamer of membrane tucks away inside the cell in neat, well-defined pleats. “When you store pleats on the helical angle in this way, you can store an infinite amount of material,” Flaum explained. “Biology has figured this out.” Geometry Is Destiny The elegance is in the arithmetic. It is mathematically impossible for this structure to unfold in any other way – and, conversely, only one way it can retract. What is perhaps more striking to Prakash is the robustness of the architecture. In its lifetime, L. olor will perform this projection and retraction 50,000 times without flaw. He said: “L. olor is bound by its geometry to fold and unfold in this particular way.” The key is an under-studied mathematical phenomenon occurring at the precise point where the ribs twist and the folded membrane begins to unfurl. It is a singularity – a point where the structure is folded and unfolded at the same time. It is both and neither – singular. Grabbing a piece of paper, Prakash folds it into a cone shape and then pulls on one corner of the paper to demonstrate how this singularity (called d-cone) travels across the sheet in a neat line. And, by pushing back on the corner how the singularity travels back the exact same path to its original position. “It unfolds and folds at this singularity every time, acting as a controller. This is the first time a geometric controller of behavior has been described in a living cell.” Prakash explained. Recreational Biology and Future Applications A constant theme running throughout the Prakash Lab’s work is a profound sense of wonder and playfulness that results in the energetic curiosity necessary to pursue such an idea for such a long time. It is, to put it in Prakash’s terms, old-school science. He also refers to it as recreational biology. To demonstrate his inspiration, Prakash displayed a family tree of other single-celled organisms that he has chosen to study. True, none can do what L. olor can do, he said. But these intricate geometries come in thousands of forms. Beautiful? Certainly, but each is also hiding wonderful and unwritten rules under their sleeves. “We started with a puzzle,” Prakash explained with all the seriousness a scientist can muster. “Ellie and I asked a very simple question: Where does this material come from? And where does it go? As our playground, we chose Tree of Life. Seven years later, here we are.” As for practical applications, Prakash the engineer is already imagining a new era of deployable microscale “living machines” that could transform everything from space telescopes to miniature surgical robots in the operating room. Reference: “Curved crease origami and topological singularities enable hyperextensibility of L. olor” by Eliott Flaum and Manu Prakash, 7 June 2024, Science. DOI: 10.1126/science.adk5511 Prakash is also a senior fellow at the Stanford Woods Institute for the Environment, associate professor (by courtesy) of biology and of oceans, a member of Stanford Bio-X, the Wu Tsai Human Performance Alliance, the Maternal & Child Health Research Institute, and the Wu Tsai Neurosciences Institute. This research was funded by the National Institutes of Health, the National Science Foundation, the Moore Foundation, the Howard Hughes Medical Institute, the Schmidt Foundation, and the Chan Zuckerberg Biohub San Francisco. Some of this work was performed at the Cell Sciences Imaging Facility at Stanford.

Bulb-like axon terminals of cone photoreceptors in the marmoset’s foveal retina. The blue pedicle, a short wavelength sensitive neuron, gives rise to complex circuitry that starts a neural code for color perception. Credit: Yeon Jin Kim/University of Washington Biological Structure Research Indicates That Certain Neural Cell Circuits Responsible for Color Vision Are Exclusive to Humans Research in the field of color vision has uncovered new evidence suggesting that humans have the capability to detect a broader spectrum of blue hues compared to monkeys. According to researchers, “distinct connections found in the human retina may indicate recent evolutionary adaptations for sending enhanced color vision signals from the eye to the brain.” Their findings were published on April 25 in the journal Proceedings of the National Academy of Sciences (PNAS). Yeon Jin Kim, acting instructor, and Dennis M. Dacey, professor, both in the Department of Biological Structure at the University of Washington School of Medicine in Seattle, led the international, collaborative project. They were joined by Orin S. Packer of the Dacey lab; Andreas Pollreisz at the Medical University of Vienna, Austria; as well as Paul R. Martin, professor of experimental ophthalmology, and Ulrike Grünert, associate professor of ophthalmology and visual science, both at the University of Sydney, Australia, and the Save Sight Institute. Comparative Study of Human and Monkey Retinas The scientists compared connections between color-transmitting nerve cells in the retinas of humans with those in two monkeys, the Old World macaque and the New World common marmoset. The ancestors of modern humans diverged from these two other primate species approximately 25 million years ago. By using a fine-scale microscopic reconstruction method, the researchers wanted to determine if the neural wiring of the areas associated with color vision is conserved across these three species, despite each taking their own independent evolutionary pathways. The scientists looked at the lightwave-detecting cone cells of the fovea of the retina. This small dimple is densely packed with cone cells. It is the part of the retina responsible for the sharp visual acuity needed to see important details, such as words on a page or what’s ahead while driving, and for color vision. Cone cells come in three sensitivities: short, medium, and long wavelengths. Information about color comes from neural circuits that process information across different cone types. Unique Short-Wave Cone Circuit in Humans The researchers discovered that a certain short-wave or blue-sensitive cone circuit found in humans is absent in marmosets. It is also different from the circuit seen in the macaque monkey. Other features the scientists found in the nerve cell connections in human color vision were not expected, based on earlier nonhuman primate color vision models. A better understanding of the species-specific, complex neural circuitry that codes for color perception could eventually help explain the origins of the color vision qualities that are distinct to humans. The researchers also mentioned the possibility that differences among mammals in their visual circuitry could have been at least partially shaped by their behavioral adaptation to ecological niches. Marmosets live in trees whereas humans prefer to dwell on land. The ability to spot ripe fruit among the shifting light of a forest, for example, may have offered a selective advantage for particular color visual circuity. However, the actual effects of environment and behavior on color vision circuitry have not yet been established. More generally, comparative studies of neural circuits at the level of connections and signaling between nerve cells, the researchers noted, could help answer many other questions. These include elucidating the underlying logic of neural circuit design and providing insight into how evolution has modified the nervous system to help shape perception and behavior. Reference: “Comparative connectomics reveals noncanonical wiring for color vision in human foveal retina” by Yeon Jin Kim, Orin Packer, Andreas Pollreisz, Paul R. Martin, Ulrike Grünert and Dennis M. Dacey, 25 April 2023, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2300545120 The study was funded by the National Institutes of Health and the National Eye Institute.

A global collaboration has created the world’s most comprehensive primate brain atlas with 4.2 million cells, unveiling region-specific functionalities and associations with neurological diseases, paving the way for future brain research and disease interventions. More than 4 million cells profiled to make largest atlas to date to help explore the evolution of the human brain and new targets for disease and treatments. A longstanding mystery in science is how the over 100 million individual neurons work together to form a network that forms the basis of who we are – every human thought, emotion, and behavior. A Global Brain Mapping Initiative Mapping these constellations of cells and discovering their function have been long-standing goals of scores of 21st century molecular cartographers working worldwide as part of the National Institutes of Health’s “Brain Initiative Cell Census Network” project. The overarching purpose of the atlas is to aid in the development of neuroscience research. The hope of the project is that it will allow scientists to gain a better understanding of brain diseases and hard-to-solve medical mysteries behind disorders such as autism and depression. Groundbreaking Discoveries Now, a series of new studies has revealed the widespread profiles of the inner molecular workings of the brain at an unprecedented level and scale. As part of the effort to better understand the evolution of the brains in people and animals, a research team led by scientists at Arizona State University, University of Pennsylvania, the University of Washington, and the Brotman Baty Institute generated the world’s largest primate brain-wide atlas. “Mapping what cells are where and what they do in the adult primate brain is crucial both for understanding the evolution of human cognition and behavior as well as for identifying what happens when things go wrong and lead to neurological disorders,” said senior co-author Noah Snyder-Mackler, an associate professor at Arizona State University’s School of Life Sciences and Center for Evolution and Medicine. Their goal was to identify and examine many of the brain cells (neurons and non-neurons) and perform a complete molecular analysis using state-of-the-art single-cell technologies. To do so, they used samples from 30 different brain regions to draw out and build up, cell by cell, a new atlas. Altogether, the final map was composed of a 4.2 million cellular atlas of the adult primate brain. “Our data, which we have made open and available to the scientific community and broader public, represent the largest and most comprehensive multimodal molecular atlas in a primate to date, and are crucial for exploring how the many cells of the brain come together to give rise to the behavioral complexity of primates including humans,” said senior co-author Jay Shendure, a professor of Genome Sciences at the University of Washington and Director of the Brotman Baty Institute. “These data will also provide a critical and much-needed map of complex human-relevant social behavior and disease, as well as the substrate for identifying similarities and differences in these cells and networks across species,” said senior co-author Michael Platt, a professor in the Departments of Neuroscience, Psychology, and Marketing at the University of Pennsylvania. Delving Deeper: Multi-Omic Analysis For every cell nucleus, the scientists profiled gene expression (2.58 million transcriptomes) and a suite of complementary DNA gene regulatory regions (1.59 million epigenomes). Taken together, this type of “multi-omic” analysis allowed the authors to study the molecular blueprints that make up distinct brain cell types, thus providing an opportunity to study, and even manipulate, key cells in more detail. From the gene expression profiles, they were able to identify hundreds of molecularly distinct brain cell types. They also found that cell composition differed extensively across the brain, revealing cellular signatures of region-specific functions, from the neurotransmitters involved in brain cell communication to support cells that help feed and protect the brain from diseases like Alzheimer’s. They used their data to investigate a total of 53 phenotypes relevant to risk of neurological diseases, disorders, syndromes, behaviors, or other traits. Their results captured known roles of cell classes implicated in neurological diseases, including cells linked to cardioembolic stroke or ischemic stroke, the leading cause of neurological death in people. They also found that genes linked to Alzheimer’s disease tended to fall within DNA regulatory regions that are only accessible in microglia—the brain’s primary immune cell that protects neurons—consistent with the prominent role of microglia proliferation and activation in Alzheimer’s disease found from genome-wide association studies (GWAS). Many of the regulatory regions they identified were new, which allowed the team to explore the genetic architecture of neurological disease risk at the cellular level. “We identified numerous associations between genetic risk for neurological disorders and the epigenomic states of specific cell types–some of which had yet to be connected,” said co-lead author Kenneth Chiou, postdoc in the Center for Evolution and Medicine and School of Life Sciences at ASU. Another type of cell class, basket cells, were enriched for the greatest number of GWAS phenotypes, including disorders such as schizophrenia, bipolar disorder, major depressive disorder and, most strongly, epilepsy. They also found enrichment of Parkinson’s disease-associated sites among open regions in the glial OPC, oligodendrocyte, and astrocyte cell classes. Finally, they found that heritable sites associated with attention deficit/hyperactivity disorder (ADHD) in their analysis were enriched only among open regions of medium spiny neurons. Medium spiny neurons have been linked to behavioral hyperactivity and disrupted attention via activation of astrocyte-mediated synaptogenesis. Their results suggest that medium spiny neurons may be a promising new target for future ADHD-related study. Together, “multi-omic” atlas now provides an open resource to the worldwide research community for further investigations into the evolution of the human brain and identifying novel targets for disease interventions. Reference: “A single-cell multi-omic atlas spanning the adult rhesus macaque brain” by Kenneth L. Chiou, Xingfan Huang, Martin O. Bohlen, Sébastien Tremblay, Alex R. DeCasien, Diana R. O’Day, Cailyn H. Spurrell, Aishwarya A. Gogate, Trisha M. Zintel, Cayo Biobank Research Unit, Madeline G. Andrews, Melween I. Martínez, Lea M. Starita, Michael J. Montague, Michael L. Platt, Jay Shendure and Noah Snyder-Mackler, 12 October 2023, Science Advances. DOI: 10.1126/sciadv.adh1914

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