Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Thailand pillow OEM manufacturer

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.ODM pillow factory in Taiwan

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.High-performance graphene insole OEM Thailand

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Insole ODM factory in Thailand

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Taiwan graphene sports insole ODM factory

Microscopy images of biological cells: top right (green) – Vimentin intermediate filaments in fibroblasts; bottom left (red) – Keratin intermediate filaments in epithelial cells. Scale: 10 µm. Credit: top right (green): Ulrike Rölleke. bottom left (red): Ruth Meyer Göttingen University Researchers Discover Surprising Properties of the Cytoskeleton Most biological cells have a fixed place in an organism. However, there are instances where these cells acquire mobility, enabling them to traverse the body. Such occurrences are seen during processes like wound recovery, or when cancerous cells divide indiscriminately and spread throughout the body. The characteristics of mobile and stationary cells exhibit several differences, one notable one being the structure of their cytoskeleton. This structure of protein filaments makes the cells stable, stretchable, and resistant to external forces. In this context, “intermediate filaments” play an important role. Interestingly, two different types of intermediate filaments are found in mobile and stationary cells. Researchers at the University of Göttingen and ETH Zurich have succeeded in precisely measuring and describing the mechanical properties of the two filaments. In the process, they discovered parallels with non-biological materials. The results have been published in the journal Matter. The scientists used optical tweezers to investigate how the filaments behave under tension. They attached the ends of the filaments to tiny plastic beads, which they then moved in a controlled way with the help of a laser beam. This stretched the two different types of filaments, which are known as vimentin and keratin. The researchers worked out which forces were necessary for the stretching and how the different filaments behaved when they were stretched several times. Surprisingly, the two different filaments behave in contrasting ways when repeatedly stretched: vimentin filaments become softer and retain their length, keratin filaments become longer and retain their stiffness. Parallels Between Biological and Non-Biological Materials The experimental results match computer simulations of molecular interactions: in vimentin filaments, the researchers assume that structures open up, similar to gels made of several components; in keratin filaments, they assume that structures shift against each other, as in metals. Both mechanisms explain that the networks of intermediate filaments in the cytoskeleton can be deformed very strongly without being damaged. However, this protective factor is explained by fundamentally different physical principles. “These results extend our understanding of why different cell types have such different mechanical properties,” explains Dr Charlotta Lorenz, first author of the study. Professor Sarah Köster, from Göttingen University’s Institute of X-Ray Physics and leader of the study, adds: “We can learn from nature and think about the design of new, sustainable and transformable materials whose properties can be chosen or designed to fit the requirements exactly.” Reference: “Keratin filament mechanics and energy dissipation are determined by metal-like plasticity” by Charlotta Lorenz, Johanna Forsting, Robert W. Style, Stefan Klumpp and Sarah Köster, 22 May 2023, Matter. DOI: 10.1016/j.matt.2023.04.014

Termites of the species Neocapritermes taracua with a blue body on the back formed by laccase BP76. Credit: Dr. Aleš Buček Neocapritermes taracua termites carry a life-ending enzyme that, when mixed with another compound during attacks, produces a lethal liquid, sacrificing the termite to protect its colony. Older worker termites of the species Neocapritermes taracua protect their colonies with an unparalleled defense mechanism. When the colony is attacked, they sacrifice themselves by setting off an explosive chemical reaction, the result of which is a toxic liquid that immobilizes and poisons their adversary. Now, researchers from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, in cooperation with colleagues from the Faculty of Tropical AgriScience of the Czech University of Life Sciences in Prague, have unraveled the mysteries of these kamikaze termites. In a study published in the scientific journal Structure, Dr. Jana Škerlová and her colleagues from the scientific group of Assoc. Prof. Pavlína Maloy Řezáčová provide a detailed description of the mechanism by which the mysterious enzyme that termites carry on their backs works. Researchers from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, in cooperation with colleagues from the Faculty of Tropical AgriScience of the Czech University of Life Sciences in Prague, are unraveling the mysteries of the life of termites. Unique Defense Mechanisms of Neocapritermes Taracua The termite species Neocapritermes taracua has evolved a peculiar defense mechanism that is unparalleled in the insect world. Worker termites play a key role in it. Over their lifetime, they gradually amass a particular enzyme, blue laccase BP76, in special pockets on their backs. When their colony finds itself in danger, older individuals tear this ‘rucksack’ apart. The enzyme is then almost immediately mixed with another substance stored in the termite body, which up to this point is relatively harmless, creating a sticky liquid containing highly poisonous benzoquinones. Although this kills the kamikaze termite itself, it also immobilizes or kills the attacker. A termite of the species Neocapritermes taracua with a blue body on the back formed by laccase BP76. Credit: Dr. Aleš Buček Scientific Breakthrough in Enzyme Stability How this potentially explosive enzyme stays active in a solid state on the backs of insects was a true scientific riddle. Scientists from the Structural Biology research group at IOCB Prague have solved the puzzle with the help of X-ray crystallography. Jana Škerlová was intrigued by the fact that the blue laccase borne by termites contains an unusually strong bond between two amino acids—which are the building blocks of proteins—near the active site of the enzyme, to which the target molecule binds and where it reacts. She explains: “Unravelling the three-dimensional structure of laccase BP76 revealed that this enzyme uses a variety of stabilization strategies, which make it not only highly durable, but also fully functional even in the harsh conditions of tropical rainforests.” Due to its unique structure, laccase BP76 not only remains intact but also active even though it rests on the back of a termite throughout its entire life. This is crucial for the enzyme’s role in the defense mechanism because, in the event of an attack on the colony, the reaction must be immediate. Graphical abstract: A termite of the species Neocapritermes taracua with a blue body on its back formed by laccase BP76. Top right: the chemical reaction catalyzed by the enzyme. The increasing blue color indicates the formation of toxic products. Credit: Škerlová, J. et al. Structure 2024. https://doi.org/10.1016/j.str.2024.07.015 Lifetime Burden of Termites Termites of the species Neocapritermes taracua can live a whole lifetime with this suicidal load. Young individuals, who are still capable of doing a lot of work for their colony, carry only small amounts of the enzyme in their back pockets. The blue ‘rucksack’, in which the explosive material accumulates, grows larger over time as the insect loses strength. Its last service to the termite mound is that it is prepared to sacrifice itself for the good of the colony. Dr. Jana Škerlová (in front) & Assoc. Prof. Pavlína Maloy Řezáčová, head of the Structural Biology group at IOCB Prague. Credit: Tomáš Belloň/IOCB Prague Role of Structural Biology in Understanding Termite Defense The fact that Neocapritermes taracua termites have solid packets of an active enzyme tucked into pockets of their raincoats, which they do not hesitate to use as a weapon in an emergency, was first observed by researchers in French Guiana some years ago. That research, published in the journal Science, also bears the IOCB Prague seal. One of the researchers who collaborated on the seminal study was Professor Jan Šobotník, who is also a co-author of the present paper and currently works at the Faculty of Tropical AgriScience of the Czech University of Life Sciences. “Our discovery is an excellent illustration of the irreplaceable role of structural biology. Just as knowledge about individual components of an instrument sheds light on how it works, knowing the three-dimensional structure (i.e. the positions of individual atoms) of a molecule helps us understand a biological process. In this case, it is a unique defense mechanism of termites,” emphasizes Pavlína Řezáčová, head of the laboratory from which the research originates. Reference: “Crystal structure of blue laccase BP76, a unique termite suicidal defense weapon” by Jana Škerlová, Jiří Brynda, Jan Šobotník, Marek Zákopčaník, Petr Novák, Thomas Bourguignon, David Sillam-Dussès and Pavlína Řezáčová, 15 August 2024, Structure. DOI: 10.1016/j.str.2024.07.015

Researchers at Washington State University have identified a “bacterial vampirism” where deadly bacteria feed on human blood serum, offering new insights into bloodstream infections and potential treatments for at-risk individuals. (Artist’s concept.) Credit: SciTechDaily.com Some of the world’s deadliest bacteria seek out and feed on human blood, a newly discovered phenomenon researchers are calling “bacterial vampirism.” A team led by Washington State University researchers has found the bacteria are attracted to the liquid part of blood, or serum, which contains nutrients the bacteria can use as food. One of the chemicals the bacteria seemed particularly drawn to was serine, an amino acid found in human blood that is also a common ingredient in protein drinks. The research finding, published in the journal eLife, provides new insights into how bloodstream infections occur and could potentially be treated. Washington State University researcher Arden Baylink holds a petri dish containing salmonella bacteria. Baylink and PhD student Siena Glenn have published research showing that some of the world’s deadliest bacteria seek out and eat serum, the liquid part of human blood, which contains nutrients the bacteria can use as food. Credit: Ted S. Warren, Washington State University College of Veterinary Medicine Bacteria Studied and Experimentation “Bacteria infecting the bloodstream can be lethal,” said Arden Baylink, a professor at WSU’s College of Veterinary Medicine and corresponding author for the research. “We learned some of the bacteria that most commonly cause bloodstream infections actually sense a chemical in human blood and swim toward it.” Baylink and the lead author on the study, WSU Ph.D. student Siena Glenn, found at least three types of bacteria, Salmonella enterica, Escherichia coli, and Citrobacter koseri, are attracted to human serum. These bacteria are a leading cause of death for people who have inflammatory bowel diseases (IBD), about 1% of the population. These patients often have intestinal bleeding that can be an entry points for the bacteria into the bloodstream. Siena Glenn, a Washington State University Ph.D. student uses a high-powered microscope. Glenn, working with Assistant Professor Arden Baylink and colleagues, has published research showing that some of the world’s deadliest bacteria seek out and eat serum, the liquid part of human blood. Credit: Ted S. Warren, Washington State University College of Veterinary Medicine Using a high-powered microscope system designed by Baylink called the Chemosensory Injection Rig Assay, the researchers simulated intestinal bleeding by injecting microscopic amounts of human serum and watching as the bacteria navigated toward the source. The response is rapid — it takes less than a minute for the disease-causing bacteria to find the serum. Potential for New Treatments As part of the study, the researchers determined Salmonella has a special protein receptor called Tsr that enables bacteria to sense and swim toward serum. Using a technique called protein crystallography, they were able to view the atoms of the protein interacting with serine. The scientists believe serine is one of the chemicals from the blood that the bacteria sense and consume. “By learning how these bacteria are able to detect sources of blood, in the future we could develop new drugs that block this ability. These medicines could improve the lives and health of people with IBD who are at high risk for bloodstream infections,” Glenn said. Reference: “Bacterial vampirism mediated through taxis to serum” by Siena J. Glenn, Zealon Gentry-Lear, Michael Shavlik, Michael J. Harms, Thomas J. Asaki and Arden Baylink, 16 April 2024, eLife. DOI: 10.7554/eLife.93178.2 The study was funded by the National Institute of Allergy and Infectious Diseases.

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