Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Arch support insole OEM from Taiwan

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Graphene-infused pillow ODM Taiwan

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Orthopedic pillow OEM solutions Vietnam

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Insole ODM factory in Indonesia

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Graphene insole manufacturer in Vietnam

A new study introduces a method to infer DNA methylation patterns in non-skeletal tissues from ancient DNA, offering insights into human evolution, particularly brain function. Using an algorithm with 92% precision, researchers identified over 1,850 differential methylation sites linked to genes essential for brain development. Researchers developed a method to study DNA methylation in ancient non-skeletal tissues, revealing epigenetic changes in the brain tied to human evolution. New research presents an innovative approach to reconstructing DNA methylation patterns in non-skeletal tissues from ancient specimens, offering fresh perspectives on human evolution. By focusing on DNA methylation—a critical indicator of gene expression—this study enables scientists to investigate changes in gene activity within the brain and other tissues that are typically not preserved in the fossil record. The team applied their method to the brain, offering a deeper understanding of the evolutionary processes that shaped the human brain and neural functions. The findings could transform how we study the evolution of human complex traits. Led by PhD student Yoav Mathov under the guidance of Prof. Liran Carmel and Prof. Eran Meshorer at the Department of Genetics, Institute of Life Sciences and the Edmond & Lily Safra Center for Brain Sciences (ELSC), this research, published in Nature Ecology & Evolution, reveals a way to identify changes in DNA methylation patterns of non-skeletal tissue using ancient DNA sequences. A Breakthrough in Non-Skeletal DNA Analysis Unlike previous studies that focused on skeletal tissue—usually the only source of ancient human DNA—this new approach utilizes developmental patterns of DNA methylation to infer skeletal changes in DNA methylation that would be also observed in other tissues. By training an algorithm on methylation data from living species, the team achieved up to 92% precision in predicting DNA methylation across various tissues. Their algorithm was then applied to ancient humans, revealing over 1,850 sites of differential methylation specifically in prefrontal cortex neurons. Many of these sites are linked to genes crucial for brain development, including the neuroblastoma breakpoint family (NBPF), which has long been associated with human brain evolution. “The ability to analyze ancient DNA methylation patterns beyond bones gives us a window into how tissues, especially brain cells, have evolved epigenetically over time,” said Mathov. “This could lead to a deeper understanding of the evolutionary forces that shaped the human brain and other vital organs.” This innovative tool expands the horizons of evolutionary biology and anthropology, allowing scientists to investigate tissue-specific epigenetic changes that are not preserved in fossils. The study paves the way for new insights into the role of epigenetic changes in human evolution and the development of complex neural functions. Reference: “Inferring DNA methylation in non-skeletal tissues of ancient specimens” by Yoav Mathov, Malka Nissim-Rafinia, Chen Leibson, Nir Galun, Tomas Marques-Bonet, Arye Kandel, Meir Liebergal, Eran Meshorer and Liran Carmel, 20 November 2024, Nature Ecology & Evolution. DOI: 10.1038/s41559-024-02571-w

Scientists from Stanford University explored the mechanisms behind sensations like “tightness” from cleansers and “softness” from moisturizers. Their findings, which correlate neural activity with user feedback from thousands of women, offer a clear framework to understand the biomechanical neural processes behind the experiences of skin treatments. New research unravels the science behind skin sensations from cleansers and moisturizers. By studying skin layers, neural pathways, and user feedback, scientists provide a comprehensive understanding of the biomechanical processes that lead to these subjective experiences. Many have experienced the sensation of “tightness” from certain cleansers and “softness” from moisturizers. Reinhold H. Dauskardt, the Ruth G. and William K. Bowes Professor in Stanford’s Department of Materials Science and Engineering, and his team sought to uncover the science behind these sensations. They employed in-vitro biomechanical testing, computational neural stimulation modeling, and gathered self-assessments from thousands of participants to uncover the intricacies. Understanding the Neural Pathways When a topical treatment is applied, it modifies specific skin layers. This, in turn, triggers cutaneous mechanoreceptors, which send data to slowly adapting type I (SAI) neurons and subsequently, to the central nervous system. Factors instigating such neural responses include the contracting effect of drying cleansers on the stratum corneum, the outermost skin layer. Similarly, the application of lotions or creams can cause swelling of this layer. Key Findings and Implications The research revealed a significant link between the physical stress observed in the stratum corneum, whether from post-cleansing drying or moisturizing, and the activity of neurons located much deeper in the skin near the dermal-epidermal junction. Their neural stimulation model further solidified this connection. Predictions from the model regarding SAI neuron firing rates in full thickness skin were in line with feedback about “tightness” from surveys of 2,000 women in France and 720 women in China. Notably, these sensations were reported even 12 hours post-application in some cases. According to the authors, this research provides a comprehensive framework to fathom the biomechanical neural activation mechanism that drives the subjective experiences of topical skin treatments. For more on this research, see Sensational Science: Why Our Skin Feels “Tight” After Using a Facial Cleanser. Reference: “Sensory neuron activation from topical treatments modulates the sensorial perception of human skin” by Ross Bennett-Kennett, Joseph Pace, Barbara Lynch, Yegor Domanov, Gustavo S Luengo, Anne Potter and Reinhold H Dauskardt, 26 September 2023, PNAS Nexus. DOI: 10.1093/pnasnexus/pgad292

Green lines with dots show a pure culture of Medakamo hakoo streaked onto an agar medium. Study co-author Emeritus Professor Tsuneyoshi Kuroiwa first discovered the algae when the water in his home goldfish tank turned green after he added medaka fish (Japanese rice fish), and he decided to look at samples under his home microscope. However, where the algae originated from – the water, fish, or somewhere else – is still unknown. Credit: 2023 Sachihiro Matsunaga The discovery of ultrasmall microalgae in a home aquarium could have multiple useful applications. Researchers from the University of Tokyo have uncovered a new species of microalgae, named Medakamo hakoo, during a DNA analysis of water from a home aquarium. With its unique DNA sequence not found in any previous records, this species stands out as the smallest known freshwater green algae. Its remarkable ability to be stably cultivated at high densities opens up exciting possibilities for its use in producing valuable products for both food and industrial purposes. If you have ever encountered seaweed, navigated through vegetation in a stream, or cleared a murky green aquarium, you are familiar with algae. These diverse aquatic organisms, which come in various shapes, colors, and sizes, thrive on water, light, and nutrients. Microalgae, a type of algae that is ultrasmall and invisible to the naked eye, play a crucial role in the Earth’s ecosystem as they serve as the foundation of all aquatic food chains. They have attracted particular attention from researchers and businesses for their ability to capture carbon dioxide, their use as a biofuel, as an alternative source of protein, and more. There are tens of thousands of types of microalgae, which continue to thrive in unexpected places. This microscopic fluorescent image of a Medakamo hakoo shows a chloroplast (red), a nucleus (green), and a cytoplasm (blue) in the alga’s cell. The white scale bar indicates 500 nanometers (0.0005 millimeters). Credit: 2023 Tsuneyoshi Kuroiwa “We were very surprised to discover a new species of microalgae in just a regular home aquarium,” said Professor Sachihiro Matsunaga from the Graduate School of Frontier Sciences. “Alga were taken from the water and cultured one by one. The DNA of the alga was fluorescently stained and microscopically observed to find the one with the least amount of DNA per cell. We then sequenced the DNA of that alga and compared it to the DNA of other algae. The results did not match the DNA of any previously reported algae, indicating that it was a new species, and we named it Medakamo hakoo (M. hakoo).” Simplified Structure and Genetic Insights Microalgae are made up of relatively few genes, and this uncomplicated form makes them useful for researchers trying to identify what roles different genes play and how they could be used. Of the tens of thousands of known microalgae, many remain uncharacterized. Thanks to this latest study, we now know that not only is this a new species, but it also has the smallest known genome of any freshwater algae, as well as other useful qualities. “M. hakoo contains only one mitochondrion (for producing energy) and one chloroplast (which contains chlorophyll and creates food through photosynthesis), whereas normal plant cells contain multiple mitochondria and chloroplasts. This indicates that it is a green alga with an extremely simple cell structure,” explained Matsunaga. “From our research, we have also speculated that it has an unprecedented DNA structure and a new gene regulatory system. Its cell cycle is also strongly synchronized with the day and night cycle, which is key to effective, stable bioproduction. Due to these inherent qualities and extremely small size, M. hakoo can be effectively cultured at high cell density, making it possible to mass produce substances such as highly functional foods, cosmetics, and bio-fuel at a low cost.” The researchers plan to continue to explore the potential applications for M. hakoo, both in the lab and the wider world. “Aquatic green algae are the originating organisms of today’s land plants. Thanks to this research, we can better understand the minimum number of genes required for an organism to evolve and thrive in diverse environments, which we will continue to study,” said Matsunaga. “In the future, I would like to find ways to collaborate and create useful substances from the mass cultivation of M. hakoo.” Reference: “Genomic analysis of an ultrasmall freshwater green alga, Medakamo hakoo” by Shoichi Kato, Osami Misumi, Shinichiro Maruyama, Hisayoshi Nozaki, Yayoi Tsujimoto-Inui, Mari Takusagawa, Shigekatsu Suzuki, Keiko Kuwata, Saki Noda, Nanami Ito, Yoji Okabe, Takuya Sakamoto, Fumi Yagisawa, Tomoko M. Matsunaga, Yoshikatsu Matsubayashi, Haruyo Yamaguchi, Masanobu Kawachi, Haruko Kuroiwa, Tsuneyoshi Kuroiwa and Sachihiro Matsunaga, 23 January 2023, Communications Biology. DOI: 10.1038/s42003-022-04367-9 Funding: MXT/JSPS KAKENHI funding, JST-CREST and JST-OPERA grants.

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