Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Orthopedic pillow OEM solutions China

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Pillow ODM design company in Vietnam

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Custom graphene foam processing Vietnam

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.China insole ODM for global brands

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Graphene-infused pillow ODM Vietnam

Yash Sondhi went looking for differences in color vision between two closely related moths, one of which is active at night and the other during the day. Instead, he found differences in the way they kept time. Credit: Jeremy Squire Researchers discovered a unique form of speciation in moths, driven by differences in activity times and supported by genetic changes in their clock genes. This study highlights the evolution of moths through temporal isolation, providing a concrete example of speciation at the molecular level. How does one species become two? If you’re a biologist, that’s a loaded question. The consensus is that, in most cases, the process of speciation occurs when individuals from a single population become geographically isolated. If they remain separate long enough, they lose the ability to interbreed. A new study published in the journal Proceedings of the Royal Society B: Biological Sciences demonstrates what happens when a less common form of speciation occurs. Rather than being separated by a physical barrier, such as a mountain range or an ocean, members of a species can become separated in time. The Case Study of Moths The researchers focused on two closely related moth species with overlapping ranges in the southeastern United States. “These two are very similar,” said lead author Yash Sondhi, who conducted research for the study while working at Florida International University and later at the Florida Museum of Natural History. “They’ve differentiated along this one axis, which is when they fly.” Rosy maple moths, in the genus Dryocampa, look like what you’d get if Roald Dahl painted something from a fever dream. They bear a thick lion’s mane above their head and abdomen, and their vibrant scales are the color of strawberry and banana taffy. Both male and female rosy moths fly exclusively at night. As their name implies, rosy maple moths often use maple trees as host plants. Their caterpillars can be so numerous and voracious that they sometimes strip away the leaves on a tree. Credit: Jeremy Squire Pink-striped oakworm moths, in the genus Anisota, are less flashy, with subtle grades of ochre, umber, and marl. While females of this species are active at dusk and early evening, the males prefer to fly during the day. Sondhi knew from previous research that these two groups, Dryocampa and Anisota, originated from a single species approximately 3.8 million years ago, which is relatively recent on evolutionary time scales. There’s a handful of species in the genus Anisota, all of which are active during the day. The nocturnal rosy maple moths are the only species in the genus Dryocampa. Genetic Insights from Moth Species Sondhi specializes in the biology of insect vision and saw the moth pair as the perfect opportunity to explore how vision evolves when a species switches up its pattern of activity. But things didn’t go as planned. “I went in looking for differences in color vision. Instead, we found differences in their clock genes, which in hindsight makes sense,” Sondhi said. Clock genes control the circadian rhythm of plants and animals. The ebb and flow of the proteins they create causes cells to become either active or dormant over a period of roughly 24 hours. They affect everything from metabolism and cell growth to blood pressure and body temperature. For any organism reversing its pattern of activity, clock genes are virtually guaranteed to be involved. “It’s a system that’s been retained in everything from fruit flies to mammals and plants. They all have some kind of time-keeping mechanism,” he said. Investigating Genetic Expressions Sondhi compared the transcriptomes of the two moths. Unlike genomes, which contain the entirety of an organism’s DNA, transcriptomes contain only the subset of genetic material that is being actively used to make proteins. This makes them useful for exploring differences in protein levels throughout the day. As expected, Sondhi found a number of genes that were expressed in different quantities in the two moth species. Nocturnal rosy maple moths invested more energy in their sense of smell, whereas the day-flying oakworm moth produced more genes associated with vision. Discoveries in Gene Expression There were, however, no differences in the genes that confer the ability to see color. That doesn’t necessarily mean that their color vision is identical, but if differences do exist, they are likely at the level of tuning and sensitivity and not in the structure of the genes themselves. There was an additional gene that stood out. Disconnected, or disco, was expressed at different levels during the day and night in both species. In fruit flies, disco is known to indirectly influence circadian rhythms through the production of neurons that transmit clock enzymes from the brain to the body. The disco gene Sondhi found in his moth samples was twice the size of its fruit fly counterpart, and it had additional zinc fingers — active portions of a gene that directly interacts with DNA, RNA and proteins. It seemed likely that changes in the disco gene were at least partially responsible for the switch to night-flying in rosy maple moths. When he compared the disco gene of rosy maple moths with the one in oakworms, he found 23 mutations that made each distinct from the other. The mutations were also located in active portions of the gene, meaning they likely contribute to observable physical differences between the moths. Sondhi was looking at evolution in action. “If this is functionally confirmed, this is a really concrete example of the mechanism behind how they speciated at the molecular level, which is rare to come by,” he said. Implications for Evolutionary Biology The study is also an important push for a better understanding of the various ways in which life sustains and propagates itself. When genetics first became a field of study, researchers focused most their efforts on a few representative species, such as fruit flies or lab mice. This was done primarily for the sake of expediency, but it limits how much we know about broad biological patterns. Just as a human is not a lab mouse, a moth is not a fruit fly. “As species continue to decline due to climate change and other anthropogenic changes, we’ll need to genetically engineer a greater number of the ones that remain to enable drought tolerance, for example, or to be active in light polluted regimes. To do that consistently, having a broader pool of functionally characterized genes across organisms is crucial. We can’t just use Drosophila,” Sondhi said. Reference: “Day–night gene expression reveals circadian gene disco as a candidate for diel-niche evolution in moths” by Yash Sondhi, Rebeccah L. Messcher, Anthony J. Bellantuono, Caroline G. Storer, Scott D. Cinel, R. Keating Godfrey, Andrew J. Mongue, Yi-Ming Weng, Deborah Glass, Ryan A. St Laurent, Chris A. Hamilton, Chandra Earl, Colin J. Brislawn, Ian J. Kitching, Seth M. Bybee, Jamie C. Theobald and Akito Y. Kawahara, 1 August 2024, Proceedings B. DOI: 10.1098/rspb.2024.0591

Researchers have discovered that ravens and humans interacted significantly more than 30,000 years ago, suggesting that ravens fed on human hunters’ mammoth scraps and possibly served as a supplementary food source. The research implies that human activities had a significant impact on ecosystems and promoted synanthropy (the beneficial sharing of habitats with humans), affecting both human culture and the likelihood of zoonotic disease transmission. Scientists from the University of Tübingen and the Senckenberg Centre for Human Evolution and Palaeoenvironment examine human-raven relationships. Long before the establishment of the first Neolithic settlements around 10,000 years ago, humans and wild animals had already formed diverse relationships. An international study conducted by experts from the Universities of Tübingen, Helsinki, and Aarhus offers new insights into these interactions. They provide evidence showing that over 30,000 years ago, during the Pavlovian culture, ravens helped themselves to people’s scraps and picked over mammoth carcasses left behind by human hunters. This took place in the region known today as Moravia, in the Czech Republic. The large number of raven bones found at the sites suggests that the birds, in turn, were a supplementary source of food, and may have become important in the culture and worldview of these people. Relations between humans, ravens and other animals 30,000 years ago. Credit: University of Tübingen The study’s lead authors are Dr. Chris Baumann, who currently conducts research at the Universities of Tübingen and Helsinki, and Dr. Shumon T. Hussain from Aarhus University, an expert in the deep history of human-animal interaction, along with Professor Hervé Bocherens of the University of Tübingen and the Senckenberg Centre for Human Evolution and Palaeoenvironment. The study has been published in the journal Nature Ecology and Evolution. In an earlier study, published in Archaeological and Anthropological Sciences, Chris Baumann described a general framework for the study showing that animal-human coexistence goes back deep into the Pleistocene. In it, he argued that such relationships likely shaped early ecosystems. A similar Food Spectrum Ravens have a very wide food spectrum, and are curious and flexible in their behavior. Their bones were discovered in large numbers at the archaeological sites of Předmostí, Pavlov I, and Dolní Věstonice I in southern Moravia. “The number of raven remains at these sites is remarkable and very unusual for the time period,” says Shumon T. Hussain. The researchers suspected that the ravens were living close to humans, perhaps attracted by their settlement activities. The research team examined the bones of twelve common ravens from the sites and determined the birds’ diet by analyzing the nitrogen, carbon, and sulfur stable isotope compositions in the bones. “These ravens fed predominantly on the meat of large herbivores, often mammoth, much like humans did at the time,” Chris Baumann explains. “We draw the conclusion that they were attracted to mammoth carcasses available near human camps.” According to the team, the animals’ behavior was oriented toward what humans were doing in their environment. They say humans, in turn, took advantage of it, catching ravens, possibly for their feathers and meat. Such evidence is important for understanding early hunter-gatherer ecosystems. The researchers propose that raven behavior was synanthropic, which means that the birds benefited from a shared ecosystem with human hunter-gatherers. The Myth of Pristine Nature “It is often assumed that early human foragers lived in and with a practically untouched natural environment. However, this is certainly too simple. We now know that human behavior impacted and changed ecosystems at least 30,000 years ago and that this had important effects for other organisms,” says Chris Baumann. Food scraps left by humans provided a stable food base for small scavengers and enabled novel human-adapted feeding niches to emerge. Such niches were exploited progressively over time and likely became key for some species, he says. At the same time, the respective animals became more important for human cultures. A possible side-effect of these developments was the increased likelihood of zoonoses – infectious diseases which can be transmitted between humans and animals. References: “Evidence for hunter-gatherer impacts on raven diet and ecology in the Gravettian of Southern Moravia” by Chris Baumann, Shumon T. Hussain, Martina Roblíčková, Felix Riede, Marcello A. Mannino and Hervé Bocherens, 22 June 2023, Nature Ecology & Evolution. DOI: 10.1038/s41559-023-02107-8 “The paleo-synanthropic niche: a first attempt to define animal’s adaptation to a human-made micro-environment in the Late Pleistocene” by Chris Baumann, 20 April 2023, Archaeological and Anthropological Sciences. DOI: 10.1007/s12520-023-01764-x

Differentiated cortical neurons expressing the axonal marker Tau (green) and the dendritic marker MAP-2 (red). Credit: Dr. Robert Williams, University of Bath Scientists are starting to understand the precise workings of a type of gene that, unlike other genes, does not code for proteins – the building blocks of life. New research shows the mechanism by which genes coding for a subset of long non-coding RNA (lncRNA) interact with neighboring genes to regulate the development and function of essential nerve cells. Scientists at the University of Bath led the study. Despite the prevalence of genes coding for lncRNA in the genome (estimates range from 18,000-60,000 lncRNA genes in the human genome compared to 20,000 protein-coding genes), these segments of DNA were previously written off as junk precisely because the information contained within them does not result in the production of a protein. However, it is now evident that some lncRNAs are anything but trash, and these might end up being crucial in helping those with severe nerve damage regain their physical abilities.  LncRNA-Protein Gene Pairs Regulate Brain Development A subset of lncRNA genes are co-expressed in the brain with neighboring genes that code for proteins involved in gene expression regulation, even though the function of the majority of lncRNA genes is still unknown. In other words, genes for these lncRNAs and their protein-coding neighbors work as a pair. Together, they control how vital nerve cells form and function, notably in the brain throughout embryonic development and early life. The regulatory pathway involved in controlling the levels of one of these gene pairs is described in the new study. Their location and quantity in the genome need to be carefully coordinated, as does the timing of their activity. “We previously defined one of the most profound functions for lncRNA in the brain and our new study identifies an important signaling pathway that acts to coordinate the expression of this lncRNA and the key protein coding gene that it is paired with,” explains Dr. Keith Vance, lead author of the study from the Department of Biology & Biochemistry at Bath. “This new research takes us closer to understanding the basic biology of nerve cells and how they are produced. Regenerative medicine is the end-game and with further research we hope to develop a deeper understanding of how lncRNA genes operate in the brain.”  “This knowledge could be important for scientists looking for ways to replace defective neurons and restore nerve function – for instance in people who have had strokes,” explains Vance. Reference: “Chromatin interaction maps identify Wnt responsive cis-regulatory elements coordinating Paupar-Pax6 expression in neuronal cells” by Ioanna Pavlaki, Michael Shapiro, Giuseppina Pisignano, Stephanie M. E. Jones, Jelena Telenius, Silvia Muñoz-Descalzo, Robert J. Williams, Jim R. Hughes and Keith W. Vance, 16 June 2022, PLOS Genetics. DOI: 10.1371/journal.pgen.1010230 The research was funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and is published today in PLOS Genetics.

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