Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw

Taiwan athletic insole OEM supplier

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Innovative pillow ODM solution in Taiwan

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Memory foam pillow OEM factory Taiwan

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.China graphene material ODM solution

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.PU insole OEM production in Taiwan

Researchers  have identified ancient unmodified agave species cultivated by early cultures, emphasizing their significance for sustainable agriculture in today’s changing climate. Above is a picture of Agave phillipsiana. Credit: Wendy Hodgson/Annals of Botany Unaltered agave species cultivated by early cultures offer insights into sustainable, drought-resistant agriculture. New findings recently published in the journal Annals of Botany reveal that researchers have found unaltered agave plant species cultivated by several early cultures including the Hohokam people, a large Native American group in the Southwest that existed between 300 and 1500 CE. Agave plants have been of great economic and social importance in the Americas for at least 9,000 years. Before people cultivated corn, agave plants were one of their main carbohydrate sources. Archaeological research indicates the Hohokam increased agricultural potential by building terraces for agave dry farming. Agricultural features such as terraces and rock piles were especially characteristic of this culture’s farming practices with the increase of dense, aggregated populations. While crops native to the Americas (corn/maize, peanuts, potatoes, tomatoes, etc.) are common around the world today, virtually all these plants have been modified extensively by European colonists and their descendants. Modern Exploration and Re-Discovery Since the 1980s, concurrent with archaeological explorations, Desert Botanical Garden research staff continue to document and study agaves throughout Arizona and the Southwest and northern Mexico. Their work resulted in the rediscovery and naming of five of the six known agave species that represent remnant populations of plants domesticated and farmed by pre-contact peoples in today’s Arizona landscape: Agave murpheyi, Agave delamateri, Agave phillipsiana, Agave sanpedroensis, Agave verdensis, and Agave yavapaiensis. Although once grown on a large scale, some clones of these agaves have continued to persist through the centuries still within ancient, constructed fields in today’s modern landscape from southern Arizona north to the Grand Canyon. These pre-contact domesticated agaves are morphologically distinct from Southwest U.S. and northern Mexico wild agaves and Mesoamerican wild and domesticated species. The remnant clones present a rare opportunity to examine plant species that are virtually unchanged since they were last cultivated prehistorically. Significance and Conservation of These Agave Species The researchers here believe that providing protection to these newly uncovered agave species is particularly relevant today because of increased interest and research in the surviving wild relatives of contemporary crops. This is particularly true of plants that occupy hot, dry environments, where climate change has rendered such plants more attractive for agricultural development. “It is hoped that our work, made more fruitful as a result of input from archaeologists and Indigenous Peoples, will foster our understanding of today’s landscapes as legacies of past human activities, rather than pristine environments,” said the paper’s lead author, Wendy Hodgson. “Pre-contact peoples were superb agriculturists, selecting, domesticating, and cultivating crops in the arid Southwest. We have the rare opportunity to study how and what kinds of agaves ancient farmers grew, especially significant today when there is a need to explore the benefits of growing drought-adapted crops using sustainable agroecological methods.” Reference: “Pre-contact agave domesticates – living legacy plants in Arizona’s landscape” by Wendy C Hodgson, E Jane Rosenthal and Andrew M Salywon, 10 October 2023, Annals of Botany. DOI: 10.1093/aob/mcad113

In lab tests, the new compound destroys 10 strains of antibiotic-resistant MRSA. A compound that both inhibits the MRSA superbug and renders it more vulnerable to antibiotics in lab experiments has been discovered by researchers at the University of Bath in the UK. Antibiotic resistance poses a major threat to human health around the world, and Staphylococcus aureus has become one of the most notorious multidrug-resistant pathogens. Led by Dr. Maisem Laabei and Dr. Ian Blagbrough at the University of Bath, scientists have discovered a compound that both inhibits the Methicillin-resistant Staphylococcus aureus (MRSA) superbug and renders it more vulnerable to antibiotics. Staphylococcus aureus (staph) is a type of bacteria found on people’s skin. Staph bacteria are usually harmless, but they can cause serious infections that can lead to sepsis or death. Methicillin-resistant Staphylococcus aureus (MRSA) is a cause of staph infection that is difficult to treat because of resistance to some antibiotics. The novel compound – a polyamine – seems to destroy S. aureus, the bacterium that causes (among other things) deadly MRSA infections, by disrupting the pathogen’s cell membrane. The compound was tested in-vitro against 10 different antibiotic-resistant strains of S. aureus. Some of the strains tested are known to be resistant to vancomycin – the final drug of choice given to patients fighting an MRSA infection. The new compound was completely successful against all strains, resulting in no further bacterial growth. As well as destroying S. aureus directly, the study demonstrates that the compound is able to restore the sensitivity of multidrug-resistant strains of the bacteria to three important antibiotics (daptomycin, oxacillin, and vancomycin). This could mean that antibiotics that have lost their effectiveness through decades of overuse may, in time, reclaim their capacity to bring serious infections under control. “We’re not entirely sure why these synergies occur between the compound and antibiotics, but we’re keen to explore this further,” said Dr. Laabei, a researcher from the Department of Live Sciences at Bath. The Pathogen’s Vulnerability Polyamines are naturally occurring compounds found in most living organisms that interact with negatively charged molecules such as DNA, RNA, and proteins. Until a decade ago, they were thought to be essential to all life, but scientists now know they are both absent in, and toxic to, S. aureus. Since making this discovery, scientists have been attempting to exploit the pathogen’s unusual vulnerability to polyamines to inhibit bacterial growth. Now Dr. Laabei and his colleagues have found that a modified polyamine (named AHA-1394) is far more effective at destroying antibiotic-resistant strains of S. aureus than even the most active natural polyamine. Transmission electron microscope image of MRSA clinical isolate at 300,000x magnification. Credit: Maisem Laabei/University of Bath Explaining, Dr. Laabei said: “Using our novel compound, the pathogen is destroyed – meaning growth is inhibited – when it’s used at a concentration that’s over 128 times lower than that required to destroy the pathogen when we use a natural polyamine. “This is important, as drugs that have the lowest minimum inhibitory concentration are likely to be more effective antimicrobial agents, and to be safer to the patient.” Though further research is needed, Dr. Laabei believes the new compound “could have important implications in a clinical setting as a new treatment option.” He said: “Preliminary research suggests the compound is non-toxic to humans, which of course is essential. In our next study, for which we’re seeking funding, we hope to focus on the precise mechanisms used by the compound to inhibit S. aureus. We believe the compound attacks the membrane of S. aureus, resulting in the membrane becoming permeable, resulting in bacterial death.” The compound was also tested against biofilm – the thin, hard-to-treat layer of microorganisms that grows on hard surfaces (seen, for instance, as plaque on teeth or a stubborn film on urinary catheters) and can result in serious infection. The results were promising here too, with the compound preventing the formation of new biofilm, though not disrupting established biofilm. Antibiotic Resistance Antibiotic resistance (or antimicrobial resistance – AMR) poses a major threat to human health around the world, and S. aureus has become one of the most notorious multidrug-resistant pathogens. A recent study looking back at the health effects of AMR in 2019 finds the pathogen was associated with one million deaths worldwide, as a result of infections not responding to antibiotics. S. aureus is found in 30% of the population, living in people’s nasal passages and on the skin, and mostly it does not cause infection. Until quite recently, an MRSA infection was regarded as a hospital problem, and those affected were mostly people with an already compromised immune system. Over the past 20 years, however, for complex and only partially understood reasons, there has been an upswing in community-wide infections even among otherwise healthy individuals, bringing a sense of urgency to the quest to find fresh ways to tackle the problem. “New treatments are urgently needed to treat infections,” said Dr. Laabei. Reference: “Antibacterial activity of novel linear polyamines against Staphylococcus aureus” by Edward J. A. Douglas, Abdulaziz H. Alkhzem, Toska Wonfor, Shuxian Li, Timothy J. Woodman, Ian S. Blagbrough and Maisem Laabei, 22 August 2022, Frontiers in Microbiology. DOI: 10.3389/fmicb.2022.948343 Funding for this research came from the GW4 Generator Award (GW4-GF2-015).

The illustration shows the new function of blood monocytes, namely their ability to proliferate in tissues before differentiating into macrophages, immune cells that play important roles in maintaining body homeostasis and health. Credit: Adeline Deward – Illumine A recent study led by scientists from the University of Liège indicates a heightened role of cell proliferation in the functioning of our immune system. Cell division, or proliferation, is crucial for life, facilitating the evolution of complex organisms from a single cell and the renewal of expended cells from a handful of “stem” cells that multiply and specialize. In the context of cancer, however, this cell proliferation spirals out of control and becomes chaotic. A team of researchers at the University of Liège’s GIGA Institute has uncovered that specific blood immune cells known as monocytes in a healthy person also possess the capacity to proliferate. Their purpose is to replenish tissue macrophages, which are vital for our bodies to function correctly. These findings were recently published in the journal Nature Immunology. Monocyte Proliferation The formation of complex multicellular organisms, which human beings belong to, requires the generation of billions of cells from a limited number of progenitor cells that have first proliferated and then acquire particular morphologies and functions while assembling into tissues and organs. Our current knowledge indicates that most of the cells that constitute a living organism arise from so-called “stem” cells, which have been divided by a process called mitosis in order to give rise to a greater number of cells. These cells then stop proliferating to specialize, differentiate and form muscles, the brain, bones, immune cells, and more. When proliferation is no longer properly regulated, this can lead to the development of various diseases, among which cancers represent the most striking example. In a study published in Nature Immunology, Professor Thomas Marichal (Professor at ULiège, Welbio investigator at the WEL Research Institute) and his team from the GIGA Institute at ULiège discovered that this ability to proliferate is not merely restricted to stem cells, but is also an as-yet-unknown function of blood immune cells, the monocytes. Indeed, blood monocytes, previously considered as differentiated cells, are capable of proliferating and generating a pool of monocytes in the tissues in order to give rise to macrophages, which are important immune cells that protect us against microbes and support the proper functioning of our organs. “This is a major fundamental discovery, which changes our conception of the involvement of cell proliferation in the constitution and maintenance of our immune system,” explains Thomas Marichal, director of the study. “Our finding also suggests that the information that can be drawn from an enumeration of blood monocytes, classically carried out during a blood test, would reflect only little of what is happening at the level of the tissues, during ‘infection or inflammation, for example, since monocytes can proliferate when they enter tissues.” Controlled Proliferation for Tissue Renewal He also adds: “Fortunately, this proliferation is extremely well controlled and does not lead to a tumoral process. It has only one goal: to allow, as effectively as possible, the replacement of immune cells that populate our tissues: the macrophages.” This discovery, funded by the WEL Research Institute (WELRI – Welbio) and by the European Research Council was possible thanks to the development of new tools and the use of innovative technologies. “This study is a great example of how technological advances can drive breakthrough scientific discoveries. It would have been extremely difficult, if not impossible, to study with such a resolution this population of proliferating monocytes only 10 years ago. This required the use of state-of-the-art equipment recently acquired at the GIGA Institute, the generation of complex genomic data and very sophisticated bioinformatics analyses” explains Domien Vanneste, funded by a doctoral grant from the FNRS and first author of the study. This study paves the way for future investigations that will evaluate the possibility of manipulating or controlling monocyte proliferation for therapeutic purposes, for the benefit of enhanced health. Reference: “MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation” by Domien Vanneste, Qiang Bai, Shakir Hasan, Wen Peng, Dimitri Pirottin, Joey Schyns, Pauline Maréchal, Cecilia Ruscitti, Margot Meunier, Zhaoyuan Liu, Céline Legrand, Laurence Fievez, Florent Ginhoux, Coraline Radermecker, Fabrice Bureau and Thomas Marichal, 16 March 2023, Nature Immunology. DOI: 10.1038/s41590-023-01468-3 The study was funded by the funded by the WEL Research Institute (WELRI – Welbio) and by the European Research Council.

DVDV1551RTWW78V