Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Taiwan eco-friendly graphene material processing factory

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Vietnam OEM/ODM hybrid insole services

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.High-performance insole OEM Vietnam

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Innovative insole ODM solutions in Indonesia

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Pillow ODM design company in Taiwan

The DNA transfer method shown involves using a syringe to inject a specific species of bacterium into the petunia stigma to activate targeted genes, then isolating the resulting proteins. Credit: Purdue Agricultural Communications photo/Tom Campbell Visual marker in petunia flowers sheds light on a little-known process. A research team led by Purdue University has begun translating the intricate molecular language of petunias. The grammar and vocabulary of this language are deeply concealed within the countless proteins and other compounds that populate the cells of flowers. Being rooted to the ground, plants can’t run away from insects, pathogens, or other threats to their survival. But plant scientists have long known that they do send warnings to each other via scent chemicals called volatile organic compounds. “They use volatiles because they can’t talk,” said Natalia Dudareva, Distinguished Professor of Biochemistry and Horticulture and Landscape Architecture at Purdue. “Plants inform neighboring plants about pathogen attacks. It looks almost like immunization. Under normal conditions, you don’t see any changes in the receiver plant. But as soon as a receiver plant is infected, it responds much faster. It’s prepared for response.” Plant scientists have long known about this immunization-like priming, but until a few years ago, they had no way to study the process. They needed a marker showing that the plants had detected the volatile compounds. New Discoveries in Plant Signaling Dudareva and 13 co-authors describe new details of the detection process in a paper recently published in the journal Science. The team includes researchers from Purdue, Université Jean Monnet Saint-Etienne in France, and the University of California-Davis. PhD candidate Shannon Stirling in Natalia Dudareva’s Lab, transfers DNA into a petunia by using a syringe to inject bacterium into the stigma to activate targeted genes, then isolating the resulting proteins. Credit: Purdue Agricultural Communications photo/Tom Campbell Scientists know little about plant receptors for volatiles. Mammals and insects have them, too, but the way they perceive volatiles is too different to help researchers study the process in plants, Dudareva said. A research team led by Purdue University scientists has documented new details about how petunias use volatile organic compounds to communicate. The Role of Volatiles in Plant Protection In 2019, in the journal Nature Chemical Biology, Dudareva and her associates published their discovery of a new physiological process, “Natural fumigation as a mechanism for volatile transport between flower organs.” The study described how a plant’s floral tubes produce volatile compounds to sterilize their stigma, the part of the pistil that collects pollen, to protect against attack by pathogens. “There are a lot of sugars on the stigma, especially in petunias. It means that bacteria will grow very nicely without these volatiles present,” Dudareva said. “But if the stigma does not receive tube-produced volatiles, it’s also smaller. This was interorgan communication. Now we had a good marker — stigma size — to study this communication process.” A research team led by Purdue University scientists has documented new details about how petunia flowers use volatile organic compounds to communicate. Credit: Purdue Agricultural Communications photo/Tom Campbell Measurements made from photographs showed statistical differences in the stigma size upon exposure to volatiles, said the Science study’s lead author, Shannon Stirling, a Ph.D. student in horticulture and landscape architecture at Purdue. “You can see that this is a consistent trend,” she said. “Once you’ve looked at enough stigmas, you can see by eye that there is a slight difference in size.” A Breakthrough in Understanding Plant Responses Combined with the genetic manipulation of the potential proteins involved, the work surprisingly revealed that a karrikin-like signaling pathway played a key role in petunia cellular signaling. “Karrikins aren’t produced by plants,” Stirling said. “They’re produced when plants burn, and our plants have never been exposed to smoke or fire.” The team also documented the importance of the karrikin-like pathway in the detection of volatile sesquiterpenes. Many plants use sesquiterpenes to communicate with other plants, among other functions. Surprisingly, the identified karrikin receptor showed the ability to selectively perceive signaling from one type of sesquiterpene compound but not its mirror image, a trait called “stereospecificity.” The receptor appears to be highly selective to the compound, said study co-author Matthew Bergman, a postdoctoral researcher in biochemistry at Purdue. “The plant produces many different volatile compounds and is exposed to plenty of others,” Bergman said. “It’s quite remarkable how selective and specific this receptor is exclusively for this signal being sent from the tubes. Such specificity ensures that no other volatile signals are getting by. There’s no false signaling.” Methodological Challenges and Innovations For Stirling, the study required mastering a painstaking method for temporarily altering the levels of proteins of the petunia pistils to identify the signal-receptor protein interactions. “Pistils and stigmas are small. They’re a little difficult to work with because of their size,” she said. “Even the sheer amount of stigmas you need to get enough sample for anything is quite large because they don’t weigh much.” This method involved injecting a certain species of bacterium into the stigma to introduce targeted genes, then isolating the resulting proteins. “It’s not easy to manipulate such a small organ,” Bergman noted. “But Shannon was able to gently prick the stigma with a syringe and infiltrate it with this bacterium so delicately. She’s quite an expert at this.” Petunias are often brightly colored and smell nice, but the Purdue scientists also value them because they serve as a fertile model system for their research. Reference: “Volatile communication in plants relies on a KAI2-mediated signaling pathway” by Shannon A. Stirling, Angelica M. Guercio, Ryan M. Patrick, Xing-Qi Huang, Matthew E. Bergman, Varun Dwivedi, Ruy W. J. Kortbeek, Yi-Kai Liu, Fuai Sun, W. Andy Tao, Ying Li, Benoît Boachon, Nitzan Shabek and Natalia Dudareva, 21 March 2024, Science. DOI: 10.1126/science.adl4685 “They’ve proven quite fruitful thus far,” Bergman said.

Researchers discovered that Earth’s biodiversity 800 million years ago was richer than previously thought, identifying ancient lineages of organisms that diversified well before the Cambrian explosion. Their findings challenge long-held views about the Neoproterozoic era and highlight the adaptability of early life forms. A recent study suggests that by the Neoproterozoic period, distinct lineages of amoebae, as well as the ancestors of plants, algae, and animals, had already emerged and managed to survive the two global glaciations that covered the planet. Approximately 800 million years ago (mya), long before the formation of the supercontinent Pangea, Earth’s biodiversity was more varied than previously thought. Brazilian researchers, through the reconstruction of the evolutionary tree of life from ancient amoebas and the ancestors of algae, fungi, plants, and animals, have proposed a scenario where multiple distinct lineages of species coexisted during this era. Their findings are detailed in an article published in the Proceedings of the National Academy of Sciences of the United States of America (PNAS). According to the literature, several lineages of eukaryotes that first emerged 1.5 billion years ago diversified and established themselves during the Neoproterozoic oxygenation event (850-540 mya), when oxygen levels in the atmosphere and oceans rose significantly owing to changes in the planet’s geochemistry. Eukaryotes are organisms consisting of one or more cells in which the DNA is contained within a distinct nucleus (all life on Earth except bacteria and archaea). The study conducted by the researchers focused on the origin and divergence times of amoebozoans, showing that many of these organisms, as well as ancestors of plants, algae, fungi, and animals, survived even the two glaciations of the Cryogenian period (790-635 mya, the middle Neoproterozoic Era, preceded by the Tonian and followed by the Ediacaran). According to the snowball earth hypothesis, polar ice extended to cover the entire planet for some 100 million years during this period. Challenging Classical Theories “The classical paradigm for the Neoproterozoic was that there was practically no life on the planet apart from one or two species of bacteria and protists. In the last 15 years, however, fossils of unicellular, eukaryotic, and heterotrophic organisms have been identified at various different locations around the world. These fossils date from about 800 mya [and are termed Tonian]. All this joined our study, which reconstituted the tree of life and used maximum likelihood estimation to identify several well-established Tonian lineages of ancestors of amoebae, animals, fungi, and plants. This radically changes the paradigm for the manner in which the diversification of life occurred on our planet,” Daniel Lahr, last author of the article and a professor at the University of São Paulo’s Institute of Biosciences (IB-USP), told Agência FAPESP. Left, a fossilized thecamoebian believed to have lived 720-635 mya. Right, a specimen from a group of modern amoebozoan testate amoebae. Credit: Luana Morais and João Alcino In other words, the study dates the mass diversification of life on Earth to some 260 million years earlier than the paradigm, well before the Cambrian explosion (the emergence of new multicellular organisms at the beginning of the Cambrian period between 541 and 530 mya). During this period, the Earth was inhabited mostly by marine invertebrates such as trilobites, brachiopods, and graptolites, and had a warm and humid climate with no evidence of glaciers. “The eukaryotes remained highly diverse despite all the climate changes that occurred during the Neoproterozoic, displaying greater adaptability than expected. This is important because our reconstitution of the phylogenetic tree also serves as a basis for paleoclimate reconstruction research,” Lahr explained. “A curious aspect is that Arcellinid amoebae then lived in saltwater, whereas now they all live in freshwater. This kind of change is frequently observed in the course of evolution since time began, but it happened to all lineages in the case of these amoebae, showing once again how adaptable these organisms were.” The researchers deployed innovative techniques to reconstitute the phylogenetic (evolutionary) tree of the genus Thecamoeba, which belongs to the order Arcellinida, and on this basis to rebuild the tree of life, starting with the prime ancestors of plants, fungi, algae, and animals. “The thecamoebians were the foundation for this reconstitution. From there on up, we were able to visualize other organisms that preceded other groups and must also have been present and diversified in the period in question some 800 mya,” Lahr said. Reconstructing the Phylogenetic Tree Previous research had revealed eight new ancestral lineages of Thecamoebae, the largest group in Amoebozoa, a clade (a common ancestor and all its descendants) of protozoans with pseudopodia shaped like tubes or flat lobes used for locomotion and feeding. Thecamoebians are known as testate amoebae because of their hard carapace. “With the aid of mathematical probability modeling, we were able to determine the morphology of ancestral thecamoebians [from genetic data for species now alive on Earth] and compare it with the fossil morphology. In this study we identified ancestral thecamoebian lineages and the augmented diversification of these organisms in the Neoproterozoic,” Lahr said. In the study described in PNAS, the scientists advanced their understanding of life on the planet 800 mya by using these thecamoebian lineages as points in calibrating the phylogenetic tree for plants, algae, fungi, animals and their ancestors. FAPESP supported the work via a regular research grant and a PhD scholarship. “In developing this extension of the tree of life, we made some interesting discoveries about a period in the planet’s history that has always been obscure. By calibrating the tree in accordance with the phylogenetic study of Thecamoebae, we were able to double the amount of information about eukaryotes in the Neoproterozoic. Our analysis of the data showed that a great diversity of lineages began to emerge in the period, one of which was animals and another fungi, possibly alongside plants,” Lahr said. One of the innovative techniques used in the study, he explained, was single-cell transcriptomics, whereby the entire transcriptome of a single cell or unicellular organism can be sequenced. The transcriptome is the set of all RNA transcripts, including coding and non-coding, in an individual or a population of cells. Transcription, the first step in gene expression, involves copying a gene’s DNA sequence to make an RNA molecule. Transcriptome sequencing enables researchers to trace the evolutionary process in reverse, identifying species that lived in the past. “Before this technique was invented, it was possible to obtain only transcriptomes of single-cell organisms living in culture, meaning less than 1% of the full diversity of microorganisms. Thanks to this innovation, we were able to structure the phylogeny of Thecamoebae as a whole. It’s a highly diverse group and is interesting because it illuminates these periods in Earth’s history that have fossil records with which we can make comparisons. Aside from this, in the tree of life, the amoebae are closer to the animals than to the plants, and this discovery enabled us to make important calibrations,” Lahr said. Reference: “Amoebozoan testate amoebae illuminate the diversity of heterotrophs and the complexity of ecosystems throughout geological time” by Alfredo L. Porfirio-Sousa, Alexander K. Tice, Luana Morais, Giulia M. Ribeiro, Quentin Blandenier, Kenneth Dumack, Yana Eglit, Nicholas W. Fry, Maria Beatriz Gomes E Souza, Tristan C. Henderson, Felicity Kleitz-Singleton, David Singer, Matthew W. Brown and Daniel J. G. Lahr, 16 July 2024, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2319628121 The study was funded by the São Paulo Research Foundation.

With a world facing the consequences of climate change, climate-resilient crops are becoming increasingly critical. By having crops that can withstand extreme environmental stressors, food security is improved, as farmers are able to grow crops even in challenging conditions. This, in turn, helps to address the issue of global hunger, as food production remains stable even in the face of a changing climate. Exotic DNA Boosts Wheat Yields in Heat The incorporation of exotic DNA from wild relatives into wheat results in a remarkable yield increase of up to 50%, even in hot weather, surpassing elite lines without these genes. Amid a year of record-breaking temperatures, research from the Earlham Institute in Norwich and the International Maize and Wheat Improvement Centre (CIMMYT) provides much-needed hope for enhancing crop resilience and securing food in the face of a changing climate. Genetic Diversity as Key to Adaptation The field trials in Mexico also emphasize the importance of genetic diversity in key crops, where decades of selective breeding have reduced their ability to adapt to a rapidly warming planet. There is growing uncertainty around the ability of major food crops to continue to meet global demand as temperatures rise and weather events become more extreme. Wheat provides more global calories than any other crop yet most of the wheat grown around the world has limited genetic variation, making it vulnerable to the impacts of climate change. “Wheat is responsible for around 20 percent of the calories consumed globally and is widely grown all over the world,” says Professor Anthony Hall, study author and Group Leader at the Earlham Institute. “But we don’t know whether the crops we’re planting today will be able to cope with tomorrow’s weather. “To make matters worse, developing new varieties can take a decade or more so acting quickly is vital.” In collaboration with CIMMYT, Earlham Institute researchers set up a two-year field trial in Mexico’s Sonora desert. They studied 149 wheat lines, ranging from widely-used elite lines to those selectively bred to include DNA from wild relatives and landraces from Mexico and India. “Crossing elite lines with exotic material has its challenges,” said Matthew Reynolds, co-author of the study and leader of Wheat Physiology at CIMMYT. “There’s a well-recognized risk of bringing in more undesirable than desirable traits, so this result represents a significant breakthrough in overcoming that barrier and the continued utilization of genetic resources to boost climate resilience.” The seeds were sown later in the season to force the plants to grow during hotter months, putting these crops under the kind of heat stress that is predicted to become the norm as global temperatures rise. Heat Tolerance Without Compromising Normal Growth They found the plants bred with exotic DNA achieved a 50 percent higher yield over wheat without this DNA. Importantly, the exotic lines didn’t perform any worse than the elite lines under normal conditions. The researchers sequenced the plants to locate specific genetic differences responsible for the increased heat tolerance. They identified genetic markers that could allow the targeted introduction of this beneficial exotic DNA into elite lines, offering a quick way to improve climate resilience and mitigate against widespread crop failures. Benedict Coombes, study author and Ph.D. student at the Earlham Institute, said: “As we try to produce more food from less land to feed a growing global population, we urgently need to future-proof the crops we’re planting so they can thrive in an increasingly hostile climate. “The key to this, we are increasingly finding, may lie within largely untapped genetic resources from wheat’s wild relatives and landraces.” Future-Proofing Wheat Crops for Global Food Security The researchers suggest breeding programs incorporate the heat tolerance traits as a pre-emptive strategy to produce wheat crops that can cope with a less predictable climate. “This is science we can now use to make an impact almost immediately,” added Professor Hall. “We’ve done the field trials, we know what genetic markers we’re looking for, and we’re starting conversations with wheat breeders so this is hopefully going to be the first of many steps to contribute to global food security in the coming years. “The discoveries we’re making, and the action we’re taking, will hopefully mean people around the world can continue to have nutritious food on their plates.” Reference: “Exotic alleles contribute to heat tolerance in wheat under field conditions” by Gemma Molero, Benedict Coombes, Ryan Joynson, Francisco Pinto, Francisco J. Piñera-Chávez, Carolina Rivera-Amado, Anthony Hall and Matthew P. Reynolds, 9 January 2023, Communications Biology. DOI: 10.1038/s42003-022-04325-5 The study was funded by UKRI-BBSRC and supported by the International Wheat Yield Partnership (IWYP) and by the Sustainable Modernization of Traditional Agriculture (MasAgro) – an initiative from the Secretariat of Agriculture and Rural Development (SADER) and CIMMYT.

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