Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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PU insole OEM production in Thailand

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Pillow ODM design company in China

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.High-performance graphene insole OEM Thailand

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Taiwan anti-odor insole OEM service

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Vietnam custom product OEM/ODM services

A research study from the University of Southampton has unveiled that corals feed on microscopic algae living within their cells, accessing a nutrient source previously thought unavailable. This discovery answers a long-standing mystery known as Darwin’s Paradox of Coral Reefs, explaining how corals flourish in nutrient-poor waters. Corals sustain growth in nutrient-poor waters by farming and consuming their symbiotic algae, but climate change may disrupt this process, threatening coral reef survival. A new study led by the University of Southampton in the UK has uncovered why coral reefs flourish in waters that appear to be deficient in nutrients, a phenomenon that has fascinated scientists since Charles Darwin. The research shows that corals farm and feed on their photosynthetic symbionts – microscopic algae that live inside their cells. This vegetarian diet allows the corals to tap into a large pool of nutrients that was previously considered unavailable to them. Effectively, they are eating some of their symbiont algae to get the nutrition they need to survive. Professor Jörg Wiedenmann, Head of the Coral Reef Laboratory at the University of Southampton, who led the study comments: “The question as to why coral reefs thrive in parts of the oceans that are poor in nutrients is known as Darwin’s Paradox of Coral Reefs and has inspired the discovery of several important processes that can help to explain this phenomenon. We can now add the missing piece of the puzzle and help to solve the long-running mystery.” Reef corals provide home and feeding grounds for many organisms. Credit: Wiedenmann / D’Angelo / University of Southampton He continues: “When Charles Darwin set sail on the HMS Beagle, he considered himself a geologist and during his voyage through tropical seas, quickly became interested in where and why coral reefs are formed. Darwin correctly predicted how the subsidence of the Earth’s crust and the steady upward growth of corals interact to form vast reef structures. However, the biological mechanisms behind this vigorous growth remained unstudied.” Surviving Together Stony corals are soft-bodied creatures that may look like plants to some, but are in fact animals. These organisms are made up of many individual polyps that live together as a colony and secret limestone skeletons which form the three-dimensional framework we know as ‘reefs’. Coral reefs are important underwater ecosystems that benefit many human communities. They provide a home and feeding ground for countless organisms, sustaining about 25 percent of global ocean biodiversity. Thereby, they deliver food and income to about half a billion people on Earth. Unicellular symbiont algae of a reef coral showing growth by cell division. Credit: Wiedenmann / D’Angelo / University of Southampton The coral animals are dependent on a ‘symbiosis’, a mutually beneficial relationship with microscopic algae that live inside their cells. The photosynthetic algae produce large amounts of carbon-rich compounds, such as sugars, which they transfer to the host coral for energy generation. The symbiont algae are also very efficient in taking up dissolved inorganic nutrients from seawater, such as nitrate and phosphate. Even in nutrient-poor oceans, these compounds can be found in considerable amounts as excretion products of organisms, such as sponges, that live close by. They can also be transferred to reefs by ocean currents. What the Scientists Found In contrast to their symbionts, the coral host cannot absorb or use dissolved inorganic nutrients directly and, until now, it was unclear how these nutrients could fuel the growth of coral. However, the mechanism by which these essential growth nutrients are transferred to the coral animals has been identified by scientists from the University of Southampton, working with a team of collaborators including Lancaster University in the UK, Tel Aviv University, and the University of Jerusalem in Israel. Their findings are published in the journal Nature. Experimental aquarium of the Coral Reef Laboratory at the University of Southampton. Credit: Wiedenmann / D’Angelo / University of Southampton By performing a series of long-term experiments at the University of Southampton’s Coral Reef Laboratory, the scientists demonstrated that corals actually digest some of their symbiont population to access the nitrogen and phosphorus that symbionts absorb from the water. Where there are sufficient dissolved inorganic nutrients in the water, this mechanism allows corals to grow quickly, even if they do not receive any additional food. Results from fieldwork in remote coral reef atolls in the Indian Ocean support the lab findings, demonstrating that this mechanism boosts coral growth in the wild at the ecosystem level. Dr Cecilia D’Angelo, Associate Professor of Coral Biology at Southampton and one of the lead authors, comments: “Over the many years during which we propagated symbiotic corals in our experimental aquarium system, we had observed that they grew very well even when they were not fed. It could not be explained by the current state of knowledge how nutrients were exchanged by the two partners of the symbiosis, so we figured that we were missing a big piece of the picture and started to analyze the process systematically.” Seabirds introduce nutrients in coral reefs in the Indian Ocean. Credit: Nick Graham, Lancaster University Dr Loreto Mardones-Velozo, a researcher in the Coral Reef Laboratory who conducted key experiments, adds: “One would expect that animals die or stop growing if they don’t eat. However, the corals looked perfectly happy and grew rapidly if we kept them in water with elevated levels of dissolved inorganic nutrients.” The Science Behind the Findings The researchers used a specifically labeled chemical compound to track the movement of the essential nutrient nitrogen between the partners of the symbiosis. Nitrogen in the chemical form used in the experiments can be only integrated in their cells by the symbionts, but not the coral host. Bastian Hambach, Manager of the Stable Isotope Mass Spectrometry Laboratory at the University of Southampton, explains: “We used isotopic labeling to ‘spike’ the nutrients supplied to the corals with nitrogen atoms that were heavier than normal. These isotopes allowed us to trace the coral’s use of the nutrients using ultrasensitive detection methods.” Dr. Cecilia D’Angelo propagating corals in the Coral Reef Laboratory at the University of Southampton. Credit: Wiedenmann / D’Angelo / University of Southampton Professor Paul Wilson, paleoceanographer at the University of Southampton expands: “With this technique, we could unambiguously demonstrate that the nitrogen atoms that sustained the growth of the coral tissue were derived from the dissolved inorganic nutrients that were fed to their symbionts in the experiment.” Professor Jörg Wiedenmann of the University of Southampton adds: “We used 10 different coral species to quantify how the symbiont population grew along with their hosts. Using mathematical models of the symbiont growth, we could show that the corals digest the excess part of their symbiont population to harvest nutrients for their growth. Our data suggest that most symbiotic corals can supplement their nutrition through such a ‘vegetarian diet’.” The scientists also analyzed corals growing around islands in the Indian Ocean, some with seabirds on them and some without, to show that corals have the potential to farm and feed on their symbionts in the wild. Growth of the experimental coral Stylophora pistillata. Credit: Mardones-Velozo / D’Angelo / Wiedenmann / University of Southampton Professor Nick Graham, Marine Ecologist from Lancaster University, explains: “The reefs around some of these islands are supplied with substantial amounts of nutrients that come from ‘guano’, the excrements of the seabirds nesting on the islands. On other islands, the seabird colonies have been decimated by invasive rats. Accordingly, the associated reefs receive less nutrients. We measured the growth of staghorn coral colonies around islands with and without dense seabird populations and found that growth was more than twice as fast on reefs that were supplied with seabird nutrients. “We calculate that about half of the nitrogen molecules in the tissue of the coral animals from islands with seabirds can be traced back to uptake by the symbionts and the subsequent translocation to the host.” Scientist monitoring coral growth on Indian Ocean Reefs to study the effect of seabird nutrients. Credit: Nick Graham, Lancaster University Global Warming and the Future Excessive nutrient enrichment, often caused by human activities, can damage corals and represents a growing threat in many reefs. However, some coral reefs might receive less nutrients in the future as global warming may cut them off from some of their natural supply routes. Dr D’Angelo from the University of Southampton explains: “Warming surface waters are less likely to receive nutrients from deeper water layers. The reduced water productivity can result in less nutrients for the symbionts and in turn less food for the coral animals.” The scientists’ new findings suggest that while coral animals may endure brief periods of starvation by feeding off their symbionts, some coral reefs might be at risk of starvation in response to more prolonged nutrient depletion brought on by global warming in some areas. Reference: “Reef-building corals farm and feed on their photosynthetic symbionts” by Jörg Wiedenmann, Cecilia D’Angelo, M. Loreto Mardones, Shona Moore, Cassandra E. Benkwitt, Nicholas A. J. Graham, Bastian Hambach, Paul A. Wilson, James Vanstone, Gal Eyal, Or Ben-Zvi, Yossi Loya and Amatzia Genin, 23 August 2023, Nature. DOI: 10.1038/s41586-023-06442-5

Recent research in the Arctic reveals that jellyfish, once considered negligible in food webs, are a key food source for amphipods during the polar night in Svalbard’s Kongsfjorden, indicating significant changes in the ecosystem due to “Atlantification.” Pictures is a ctenophore or comb jelly. Credit: C. Havermans AWI research team shows that jellyfish play an important, previously unknown role in the diet of amphipods during the polar night. The Arctic is changing rapidly due to climate change. It is not only affected by increasing surface temperatures, but also by warm water from the Atlantic, which is flowing in more and more – changing the structures and functions of the ecosystem as it also leads to species from warmer regions, such as jellyfish, arriving in the Arctic. Using DNA metabarcoding, researchers from the Alfred Wegener Institute have now been able to prove for the first time that these jellyfish serve as food for amphipods on Svalbard during the polar night and thus play a greater role in Arctic food webs than previously assumed. They present their findings in a recent article in the scientific journal Frontiers in Marine Science. The AWI researchers collected samples from four different amphipod species over the course of a month during the polar night. Credit: Alfred Wegener Institute / Charlotte Havermans Atlantification of the Arctic and Its Impact on Marine Life In recent years, warm, salty water from the Atlantic has increasingly found its way into the European Arctic. The Norwegian archipelago of Svalbard is also under the influence of this “Atlantification”: the Kongsfjorden on the west coast has switched to an Atlantic regime; the water temperature during the polar night (November to February) is increasing by around 2 degrees Celsius per decade. These changes also lead to biotic shifts, as species from warmer waters also flow into the Arctic along with the warm Atlantic water. “Some jellyfish species in particular tend to spread poleward and into the Arctic,” says Charlotte Havermans, head of the ARJEL junior research group at the Alfred Wegener Institute, Helmholtz Center for Polar and Marine Research (AWI). ” When we were in Kongsfjorden in the Polar Night in 2022, we were very surprised to see the fjord teeming with jellyfish life, consisting of many different species and life stages, and they seemed to be the dominant zooplankton in winter time.” Pink helmet jellyfish, a hydrozoan. Credit: C. Havermans Jellyfish in Arctic Food Webs In the past, jellyfish were considered a trophic dead end in marine food webs, but recent studies suggest that they are an important prey for marine invertebrates and fish. “Therefore, we wondered whether the jellyfish in Kongsfjorden also serve as food for other organisms, especially during the dark season of the polar night when other food sources are limited,” says Havermans. To answer this question, one of the team’s PhD students, Annkathrin Dischereit, analyzed the stomach contents of various amphipod species. For a month, they regularly collected samples from four different amphipod species (Gammarus oceanicus, G. setosus, Orchomenella minuta, and Anonyx sarsi) during the polar night, using baited traps and hand nets. Jellyfish Are an Integral Part of the Diet of Amphipods During the Polar Night The AWI researchers used DNA-metabarcoding to determine the food spectrum of the small crustaceans. This cutting-edge method can detect short gene fragments in the stomach, which are then compared with genetic reference databases to identify the prey species to which the fragments belong. “We found a large number of jellyfish in the stomachs of the amphipods, from the largest jellyfish in the fjord to tiny hydrozoans,” explains Charlotte Havermans. Using DNA metabarcoding, the AWI team was able to identify and categorize the soft parts of jellyfish and other organisms that had been consumed, even if they were already heavily digested. “We were able to prove for the first time that amphipod scavengers feed on the remains of jellyfish. This had previously only been shown in experimental environments.” All the species studied fed on both plant and animal matter. In addition to jellyfish, crustaceans, and macroalgae were other important components of the diet of some species, while fish species such as the polar cod or snailfish played an important role for other species. Whether the amphipods fed on eggs, larvae, carrion, or feces of fish remains to be clarified. What also remains to be determined, is whether jellyfish act as a survival food in winter, or are part of the regular prey of these organisms in all seasons. “We have always assumed that the nutritional value of jellyfish is low, but this has only been investigated for less than a handful of species, and also depends on the tissues that are utilized.” New Insights Into Arctic Marine Ecosystems The study provides completely new insights into the Arctic food web during the polar night and are the first natural, non-experimental evidence for the role of jellyfish in these webs. “The thriving, diverse jellyfish community that occurs in Kongsfjorden in winter is clearly used as a food source,” Charlotte Havermans summarises the results. “Until now, we knew nothing about the role of jellyfish as prey in this area. It was also not known that the species Gammaridea, for example, feeds on jellyfish at all, not in the Arctic, but also not elsewhere.” The question now arises as to whether this only applies to the polar night, when the food supply is limited. The ARJEL junior research group at AWI wants to continue researching this question. Because: “Jellyfish could be among the winners of climate change that will continue to spread during the global warming. We have also predicted that jellyfish will become more common in the Arctic as temperatures continue to rise,” says Havermans. As a result, their role in the food web could become increasingly important. Until now, however, our understanding of this has been limited, particularly in the polar regions. “With this study, we reveal crucial links in the Arctic food web that were so far not known. This is fundamental because we need to understand how jellyfish fit into food webs and spread in an Arctic that is changing rapidly. This also applies to the neighboring shelf seas, as ten percent of the world’s fisheries take place in these areas.” For more on this study, see The Secret Jellyfish Dinners of the Arctic Depths. Reference: “DNA metabarcoding reveals a diverse, omnivorous diet of Arctic amphipods during the polar night, with jellyfish and fish as major prey” by Annkathrin Dischereit, Jan Beermann, Benoit Lebreton, Owen S. Wangensteen, Stefan Neuhaus and Charlotte Havermans, 9 January 2024, Frontiers in Marine Science. DOI: 10.3389/fmars.2024.1327650

The study paves the way for exploring the use of CRISPR as a potential genetic therapy to muzzle the release of cat allergens. Researchers at InBio (formerly Indoor Biotechnologies), a biotech company in Virginia, report progress en route to developing a hypoallergenic cat – or at least treating patients with allergies to the domestic cat – in a new article published online in The CRISPR Journal. Journal dedicated to outstanding research and commentary on all aspects of CRISPR and gene editing research. Credit: Mary Ann Publications, Inc., publishers About 15 percent of the population suffer allergies to domestic cats, which researchers have previously shown is largely attributable to what the Atlantic called “a pernicious little protein” — an allergen called Fel d 1 that is shed by all cats. In the new study, Nicole Brackett and colleagues at InBio performed a bioinformatics analysis of the Fel d 1 gene from 50 domestic cats to pinpoint conserved coding regions suitable for CRISPR editing. Further comparisons to genes in eight exotic felid species revealed a high degree of variation, suggesting that Fel d 1 is nonessential for cats. The researchers used CRISPR-Cas9 to disrupt Fel d 1 with high efficiency. “Our data indicate that Fel d 1 is both a rational and viable candidate for gene deletion, which may profoundly benefit cat allergy sufferers by removing the major allergen at the source,” the authors write. The study paves the way for further experiments exploring the use of CRISPR as a potential genetic therapy to muzzle the release of cat allergens. Reference: “Evolutionary Biology and Gene Editing of Cat Allergen, Fel d 1” by Nicole F. Brackett, Brian W. Davis, Mazhar Adli, Anna Pomés and Martin D. Chapman, 28 March 2022, The CRISPR Journal. DOI: 10.1089/crispr.2021.0101

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