Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Thailand athletic insole OEM supplier

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Smart pillow ODM manufacturer Vietnam

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.PU insole OEM production in Indonesia

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.One-stop OEM/ODM solution provider China

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Taiwan OEM insole and pillow manufacturing factory

Scanning was completed both during Time 1 and Time 2 (approximately 1.5 years later) in each of the 5 age groups (6-year-olds, 10-year-olds, 14-year-olds, 16-year-olds, and 18+-year-olds). Credit: Zacharopoulos G, et al., 2021, PLOS Biology, CC-BY 4.0 Glutamate and GABA in the brain have reverse relationships with math ability, which switch during development. The neurotransmitters GABA and glutamate have complementary roles — GABA inhibits neurons, while glutamate makes them more active. Published today (July 22nd, 2021) in PLOS Biology, researchers led by Roi Cohen Kadosh and George Zacharopoulos from the University of Oxford show that levels of these two neurotransmitters in the intraparietal sulcus of the brain can predict mathematics ability. The study also found that the relationships between the two neurotransmitters and arithmetic fluency switched as children developed into adults. Levels of brain excitement/inhibition are thought to be related to learning, especially during critical periods. However, little is known about how they are related to complex learning that can take place over decades. To address this issue, the researchers measured the levels of GABA and glutamate in 255 people, ranging from 6-year-olds to university students. The participants also took two math achievement tests, and their performance on the arithmetic problems were correlated with the GABA and glutamate levels. The team found that among young people, higher GABA levels in the left intraparietal sulcus of the brain (a fold in the top, left, back part of the brain) were associated with greater math fluency, while the reverse was true for glutamate. In adults, the results were almost exactly opposite; low GABA concentrations were related to greater math fluency, and again, the reverse was true for glutamate. Because the participants were tested twice about 1.5 years apart, the researchers were also able to show that neurotransmitter levels at the time of the first test could predict math achievement at the later date. Much of what we know about GABA, glutamate, and learning comes from rodent experiments in the lab, which cannot say anything directly about natural school-based skills such as mathematics that develop over time. This longitudinal study in humans will help researchers better understand the relationship between learning and brain plasticity, particularly during critical periods that might span years. Cohen Kadosh adds, “Our finding of developmental switches in the link between GABA and glutamate and academic achievement highlights a general, unknown principle of plasticity. In contrast to previous studies on humans or animals that focused on narrower developmental stages, our cross-sectional-longitudinal study suggests that the link between plasticity and brain excitation and inhibition across different stages is unlikely to be immutable. Our findings have also important implications for the development of brain-based interventional programs, which we hope to examine in the future.” Reference: “Predicting learning and achievement using GABA and glutamate concentrations in human development” by George Zacharopoulos, Francesco Sella, Kathrin Cohen Kadosh, Charlotte Hartwright, Uzay Emir and Roi Cohen Kadosh, 22 July 2021, PLOS Biology. DOI: 10.1371/journal.pbio.3001325 The Wellcome Centre for Integrative Neuroimaging is supported by core funding from the Wellcome Trust (203139/Z/16/Z). This work was supported by the European Research Council (Learning&Achievement 338065) (RCK). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

A smoky mouse (Pseudomys fumeus) in the Grampians-Gariwerd National Park, Victoria, Australia. Credit: David Paul/Museums Victoria DNA Mapping of Native Rodents Across Australia and New Guinea New research has mapped the DNA from more than 150 species of native rodents from across Australia, New Guinea, and Melanesian islands. It paints a clearer picture of how they’re related and how they ended up spreading across the Pacific. Lead author Dr. Emily Roycroft from The Australian National University (ANU) said native rodents are a fascinating but often under-appreciated evolutionary group. “There are over 150 species in Australia and New Guinea that aren’t found anywhere else in the world, like the rakali – or ‘water rat’ – that’s often seen swimming around Canberra’s lakes,” said Dr. Roycroft. “Until now, we’ve known very little about the evolution and origin of native rodents, especially species in New Guinea.” Unlocking the Secrets of Rodent Evolution with Ancient DNA The research team used a new approach to get DNA from museum specimens up to 180 years old, including many extinct and elusive species. A wild Rakali (also known as the Australian Water Rat). “One specimen of Guadalcanal rat from the Solomon Islands dates back to the 1880s, and the species hasn’t been seen since. It’s listed as critically endangered, and very possibly already extinct. We were curious to revisit these old specimens using modern technology,” said Dr. Roycroft. How Mountain Formation Shaped Rodent Distribution The research reveals that mountain formation in New Guinea five million years ago was the trigger for the spread of native rodents across the region. The expansion of New Guinea opened up new environments for rodents to adapt to, including through increased connectivity with Australia, the Solomon Islands, and the Maluku Islands. “We’ve known for some time that Australia’s native rodents originated in Asia and arrived in our region via water – possibly a single pregnant animal floating across on a piece of driftwood. Now we have an accurate timeline for this, and an explanation for why we see so many species today,” said Dr. Roycroft. “Our study shows native rodents are exceptional at colonizing new areas. When they first arrived in Australia they adapted to a lot of new environments – including the arid desert. The Ecological Importance of Native Rodents Having extra information about native rodents’ history could prove vital to the future of these species, according to Dr. Roycroft. “Native rodents have a deep intrinsic value in our ecosystems. They’re ecosystem engineers; they aerate soil via burrowing and foraging and they help to disperse seeds and fungal spores,” she said. “They also play a role in food webs as an important source for native predators, and in turn, they feed on plants, fungi, and smaller animals themselves. “But they also have the highest extinction rate of any Australian mammal group, due to extreme habitat loss and introduced predators. If we lose even one native species, it can throw off the balance in an ecosystem. “Understanding how our native rodents evolved and adapted will help us to conserve those we have left.” The study has been published in the journal Current Biology. Reference: “New Guinea uplift opens ecological opportunity across a continent” by Emily Roycroft, Pierre-Henri Fabre, Anna J. MacDonald, Craig Moritz, Adnan Moussalli and Kevin C. Rowe, 2 September 2022, Current Biology. DOI: 10.1016/j.cub.2022.08.021 The research was supported by funding from Bioplatforms Australia through the Australian Government National Collaborative Research Infrastructure Strategy (NCRIS).

A study has linked a high-sugar diet to insulin resistance in the brain, impairing the removal of neuronal debris and potentially increasing the risk of neurodegenerative diseases such as Alzheimer’s. High-sugar diet in fruit flies leads to insulin resistance in the brain and impairs cleanup of neuronal waste. Researchers led by Mroj Alassaf at the Fred Hutchinson Cancer Research Center in the United States have discovered a link between obesity and neurodegenerative disorders like Alzheimer’s disease. Using the common fruit fly, the research shows that a high-sugar diet — a hallmark of obesity — causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration. Published on November 7th in the open access journal PLOS Biology, the research will impact therapies designed to reduce the risk of developing neurodegenerative diseases. Insulin Resistance and Neuronal Debris Although obesity is known to be a risk factor for neurodegenerative disorders like Alzheimer’s disease and Parkinson’s disease, exactly how one leads to the other remains a mystery. The new study focused on answering this question by taking advantage of the similarity between humans and fruit flies. Having previously shown that a high-sugar diet leads to insulin resistance in the peripheral organs of flies, the researchers now turned to their brains. Specifically, they examined glial cells because microglial dysfunction is known to lead to neural degeneration. Sugar fly. Artistic rendering generated by DALL.E using the prompt “The drawing of the fruit fly Drosophila in a dark background in the style of Seurat.” The researchers fed fruit flies high-sugar diets and examined the effect on brain function. Credit: Akhila Rajan Implications for Neurodegenerative Disease Risk Levels of the protein PI3k indicate how much a cell is able to respond to insulin. The researchers found that the high-sugar diet led to reduced PI3k levels in glial cells, indicating insulin resistance. They also looked at the fly equivalent of microglia, called ensheathing glia, whose primary function is to remove neural debris, such as degenerating axons. They observed that these glia had low levels of the protein Draper, indicating impaired function. Further tests revealed that artificial reduction of PI3k levels led to both insulin resistance and low Draper levels in ensheathing glia. Finally, they showed that after actually damaging olfactory neurons, the ensheathing glia could not remove the degenerating axons in the flies on the high-sugar diet because their Draper levels did not increase. The authors add, “Using fruit flies, the authors establish that high-sugar diets trigger insulin resistance in glia, disrupting their ability to clear neuronal debris. This study provides insight into how obesity-inducing diets potentially contribute to the increased risk of neurodegenerative disorders.” Reference: “Diet-induced glial insulin resistance impairs the clearance of neuronal debris in Drosophila brain” by Mroj Alassaf and Akhila Rajan, 7 November 2023, PLOS Biology. DOI: 10.1371/journal.pbio.3002359 Funding: This work is possible due to grants awarded to AR from the National Institute of General Medical Sciences (R35GM124593), the Brain Research foundation (BRFSG-2022-09), and the 2023 McKnight Foundation Neurobiology Disorders Award. MA is supported by a postdoctoral fellowship from the Helen Hay Whitney Foundation. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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