Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Thailand high-end foam product OEM/ODM

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.High-performance graphene insole OEM Indonesia

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.China custom insole OEM supplier

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Vietnam insole OEM manufacturer

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Pillow ODM design company in Taiwan

The Vanadis worm, a type of large-eyed bristle worm or polychaeta, exhibits eyesight comparable to that of rodents, enabling it to see UV light, focus on small moving objects, and presumably use this ability for nocturnal activities such as mating and hunting. Remarkably, the worm’s eyes are exceptionally large, weighing about 20 times more than the rest of its head, highlighting their significance in the worm’s survival strategies. Credit: Michael Bok Researchers from the University of Copenhagen and Lund University are amazed by the discovery of a bristle worm that possesses eyesight as acute as that of mammals. They suspect that they may have a secretive language, only seen by their own species. The Vanadis bristle worm has eyes as big as millstones – relatively speaking. Indeed, if our eyes were proportionally as big as the ones of this Mediterranean marine worm, we would need a big sturdy wheelbarrow and brawny arms to lug around the extra 100kg. As a set, the worm’s eyes weigh about twenty times as much as the rest of the animal’s head and seem grotesquely out of place on this tiny and transparent marine critter. As if two giant, shiny red balloons have been strapped to its body. Vanadis bristle worms, also known as polychaetes, can be found around the Italian island of Ponza, just west of Naples. Like some of the island’s summertime partiers, the worms are nocturnal and out of sight when the sun is high in the sky. So what does this polychaete do with its walloping peepers after dark? And what are they good for? Neuro- and marine biologist Anders Garm from the University of Copenhagen’s Department of Biology couldn’t ignore the question. Setting other plans aside, the researcher felt compelled to dive in and try to find out. He was hooked as soon as his colleague Michael Bok at Lund University showed him a recording of the bristle worm. “Together, we set out to unravel the mystery of why a nearly invisible, transparent worm that feeds in the dead of night has evolved to acquire enormous eyes. As such, the first aim was to answer whether large eyes endow the worm with good vision,” says Michael Bok who together with Anders Garm, authors a new research article that does just that.[LINK] It turns out that the Vanadis’ eyesight is excellent and advanced. Research has demonstrated that this worm can use its eyes to see small objects and track their movements. “It’s really interesting because an ability like this is typically reserved for us vertebrates, along with arthropods (insects, spiders, etc.) and cephalopods (octopus, squid). This is the first time that such an advanced and detailed view has been demonstrated beyond these groups. In fact, our research has shown that the worm has outstanding vision. Its eyesight is on a par with that of mice or rats, despite being a relatively simple organism with a minuscule brain,” says Garm. This is what makes the worm’s eyes and extraordinary vision unique in the animal kingdom. And it was this combination of factors about the Vanadis bristle worm that really caught Anders Garm’s attention. The researcher’s work focuses on understanding how otherwise simple nervous systems can have very complex functions – which was definitely the case here. UV light and a secret language For now, the researchers are trying to find out what caused the worm to develop such good eyesight. The worms are transparent, except for their eyes, which need to register light to function. So they can’t be inherently transparent. That means that they come with evolutionary trade-offs. As becoming visible must have come at a cost to the Vanadis, something about the evolutionary benefits of its eyes must outweigh the consequences. Precisely what the worms gain remains unclear, particularly because they are nocturnal animals that tuck away during the day, when eyes usually work best. “No one has ever seen the worm during the day, so we don’t know where it hides. So, we cannot rule out that its eyes are used during the day as well. What we do know is that its most important activities, like finding food and mating, occur at night. So, it is likely that this is when its eyes are important,” says Anders Garm. Part of the explanation may be due to the fact that these worms see different wavelengths of light than we humans do. Their vision is geared to ultraviolet light, invisible to the human eye. And according to Garm, this may indicate that the purpose of its eyes is to see bioluminescent signals in the otherwise pitch-black nighttime sea. “We have a theory that the worms themselves are bioluminescent and communicate with each other via light. If you use normal blue or green light as bioluminescence, you also risk attracting predators. But if instead, the worm uses UV light, it will remain invisible to animals other than those of its own species. Therefore, our hypothesis is that they’ve developed sharp UV vision so as to have a secret language related to mating,” says Garm, who continues: “It may also be that they are on the lookout for UV bioluminescent prey. But regardless, it makes things truly exciting as UV bioluminescence has yet to be witnessed in any other animal. So, we hope to be able to present this as the first example,” says the researcher. Exciting for robotics research and evolutionary history As a result of the discovery, Anders Garm and his research colleagues have also started working with robotics researchers from the Maersk Mc-Kinney Møller Institute at the University of Southern Denmark (SDU) who find technological inspiration in biology. Together, they share a common goal of investigating whether it is possible to understand the mechanism behind these eyes well enough so as to translate it into technology. “Together with the robotics researchers, we are working to understand how animals with brains as simple as these can process all of the information that such large eyes are likely able to collect. This suggests that there are super smart ways to process information in their nervous system. And if we can detect these mechanisms mathematically, they could be integrated into computer chips and used to control robots,” explains Ander Garm. According to Garm, Vanadis’ eyes are also interesting with regards to evolutionary theory because they could help settle one of the heaviest academic debates surrounding the theory: Whether eyes have only evolved once – and evolved into every form that we know of today, or whether they have arisen several times, independently of one another, in evolutionary history. Vanadis’ eyes are built simply, but equipped with advanced functionality. At the same time, they have evolved in a relatively short evolutionarily time span of just a few million years. This means that they must have developed independently of, for example, human eyes, and that the development of vision, even with a high level of function, is possible in a relatively short time. Reference: “High-resolution vision in pelagic polychaetes” by Michael J. Bok, Armando Macali and Anders Garm, 8 April 2024, Current Biology. DOI: 10.1016/j.cub.2024.02.055

New research has found that a group of genes that reduces the risk of developing severe COVID-19 by around 20% is inherited from Neanderthals. Credit: Bjorn Oberg, Karolinska Institutet DNA variants passed on to modern humans from Neanderthals can increase as well as decrease our ability to fight SARS-CoV-2, a new PNAS study finds. New research has found that a group of genes that reduces the risk of developing severe COVID-19 by around 20% is inherited from Neanderthals These genes, located on chromosome 12, code for enzymes that play a vital role in helping cells destroy the genomes of invading viruses The study suggests that enzymes produced by the Neanderthal variant of these genes are more efficient which helps protect against severe COVID-19 This genetic variant was passed to humans around 60,000 years ago via interbreeding between modern humans and Neanderthals The genetic variant has increased in frequency over the last millennium and is now found in around half of people living outside Africa SARS-CoV-2, the virus that causes COVID-19, impacts people in different ways after infection. Some experience only mild or no symptoms at all while others become sick enough to require hospitalization and may develop respiratory failure and die. Neanderthal Genes and Modern Immunity Now, researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) in Japan and the Max Planck Institute for Evolutionary Anthropology in Germany have found that a group of genes that reduces the risk of a person becoming seriously ill with COVID-19 by around 20% is inherited from Neanderthals. “Of course, other factors such as advanced age or underlying conditions such as diabetes have a significant impact on how ill an infected individual may become,” said Professor Svante Pääbo, who leads the Human Evolutionary Genomics Unit at OIST. “But genetic factors also play an important role and some of these have been contributed to present-day people by Neanderthals.” Last year, Professor Svante Pääbo and his colleague Professor Hugo Zeberg reported in Nature that the greatest genetic risk factor so far identified, doubling the risk to develop severe COVID-19 when infected by the virus, had been inherited from Neanderthals. Their latest research builds on a new study, published in December last year from the Genetics of Mortality in Critical Care (GenOMICC) consortium in the UK, which collected genome sequences of 2,244 people who developed severe COVID-19. This UK study pinpointed additional genetic regions on four chromosomes that impact how individuals respond to the virus. Protective Gene Variant from Neanderthals Now, in a study published recently in Proceedings of the National Academy of Sciences (PNAS), Professor  Pääbo and Professor Zeberg show that one of the newly identified regions carries a variant that is almost identical to those found in three Neanderthals – a ~50,000-year-old Neanderthal from Croatia, and two Neanderthals, one around 70,000 years old and the other around 120,000 years old, from Southern Siberia. Surprisingly, this second genetic factor influences COVID-19 outcomes in the opposite direction to the first genetic factor, providing protection rather than increasing the risk to develop severe COVID-19. The variant is located on chromosome 12 and reduces the risk that an individual will require intensive care after infection by about 22%. “It’s quite amazing that despite Neanderthals becoming extinct around 40,000 years ago, their immune system still influences us in both positive and negative ways today,” said Professor Pääbo. To try to understand how this variant affects COVID-19 outcomes, the research team took a closer look at the genes located in this region. They found that three genes in this region, called OAS, code for enzymes that are produced upon viral infection and in turn activate other enzymes that degrade viral genomes in infected cells. “It seems that the enzymes encoded by the Neanderthal variant are more efficient, reducing the chance of severe consequences to SARS-CoV-2 infections,” Professor Pääbo explained. The researchers also studied how the newly discovered Neanderthal-like genetic variants changed in frequency after ending up in modern humans some 60,000 years ago. To do this, they used genomic information retrieved by different research groups from thousands of human skeletons of varying ages. Evolutionary Advantage of the Protective Variant They found that the variant increased in frequency after the last Ice Age and then increased in frequency again during the past millennium. As a result, today it occurs in about half of people living outside Africa and in around 30% of people in Japan. In contrast, the researchers previously found that the major risk variant inherited from Neanderthals is almost absent in Japan. “The rise in the frequency of this protective Neanderthal variant suggests that it may have been beneficial also in the past, maybe during other disease outbreaks caused by RNA viruses,” said Professor Pääbo. Reference: “A genomic region associated with protection against severe COVID-19 is inherited from Neandertals” by Hugo Zeberg and Svante Pääbo, 16 February 2021, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2026309118

Postdoctoral researcher Abdelrhman Mohamed and graduate student Gretchen Tibbitts used an electric probe to measure bacterial electrochemical signals and to identify antibiotic resistance in less than 90 minutes. Credit: WSU A technique that measures the metabolic activity of bacteria with an electric probe can identify antibiotic resistance in less than 90 minutes, a dramatic improvement from the one to two days required by current techniques.  This discovery means that doctors could quickly know which antibiotics will or won’t work for a patient’s life-threatening infection, a quandary that doctors face on a daily basis in hospitals around the world.  A Washington State University research team reports on their work in the journal, Biosensors and Bioelectronics. “The idea here is to give the doctors results much more quickly so that they can make clinically appropriate decisions within that timeframe that they’re working, rather than having to wait,” said Douglas Call, Regents Professor in the Paul G. Allen School for Global Health and a co-author of the paper. “Instead of looking for growth of a culture, we look for metabolism, and that is basically what we’re detecting by the movement of these electrons so it can happen in much shorter time spans compared to a conventional culture-based assay.” The prevalence of antibiotic resistance is increasing around the world and threatens the ability to treat many common infectious diseases. For example, millions of people in the U.S. are infected annually with drug-resistant pathogens, and thousands of people die from pneumonia or bloodstream infections that become impossible to treat. To determine definitively whether a particular infection is resistant to antibiotics requires separating and then growing the bacteria in a lab and watching the population grow in a process that can take up to two days or more. Doctors who are faced with a sick patient often have to prescribe an antibiotic immediately without having complete information on how well it will work.   In their paper, the WSU team used a probe to directly measure the electrochemical signal of the bacteria, thereby measuring their metabolism and respiration and learning how they are faring long before they would be visible in culture. Looking at eight different strains of bacteria, the researchers were able to use the bacteria’s electric signal to determine in less than 90 minutes which were susceptible or resistant to the antibiotics.  The bacteria that are still metabolizing and “breathing” after antibiotic treatment are considered resistant.  Previous attempts to measure the electrochemical activity of bacteria had been limited because most bacterial species are not capable of transferring electrons directly to an electrode, said Abdelrhman Mohamed, a postdoctoral researcher in the Gene and Linda Voiland School of Chemical Engineering and Bioengineering who was a lead author on the paper. The researchers added a chemical mediator to their assay, which acted as a shuttle, taking the electrons from the surface proteins of the bacteria and moving them to the researchers’ electrode, where the electric signal can be measured.  “That allows us to have a universal mechanism that can test all types of pathogens,” said Mohamed.  The researchers tested four different bacterial species that cause hospital-acquired infections and tested a variety of antibiotics that work by way of different mechanisms. They also developed an antibiotic susceptibility index to categorize the results in a way that could help doctors decide which antibiotic to use.  The researchers are now planning to engineer their probe to be convenient and standardized for clinicians to use and hope to commercialize it.  “It’s really exciting to be involved in a project that not only is valuable from a scientific view but is something that has commercial and industrial applications that could potentially someday actually improve people’s lives,” said Gretchen Tibbits, a lead author on the paper and graduate student in the Voiland School.  They are also working to better understand the fundamental mechanisms of the electrochemical process to further improve it.  “We are doing it in two hours, but if we understand mechanisms better, maybe we can do this in minutes,” said Haluk Beyenal, co-author on the paper and a professor in the Voiland School. “As long as the bacteria are alive, we can do this measurement.” Reference: “Rapid differentiation of antibiotic-susceptible and -resistant bacteria through mediated extracellular electron transfer” by Gretchen Tibbits, Abdelrhman Mohamed, Douglas R. Call and Haluk Beyenal, 2 November 2021, Biosensors and Bioelectronics. DOI: 10.1016/j.bios.2021.113754

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