Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Innovative insole ODM solutions in Taiwan

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.ESG-compliant OEM manufacturer in Vietnam

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Thailand custom product OEM/ODM services

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Innovative pillow ODM production solution in Taiwan

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.China OEM insole and pillow supplier

The COVID-19 strain in the United States and Europe during the first wave may have been highly infectious, possibly due to coughing being the most common initial symptom. COVID-19 may have spread faster in US because first symptom was cough. Study by USC researchers finds that the order of symptoms in the first wave of COVID-19 varied among virus strains. The strain of COVID-19 virus that was circulating in the United States and Europe during the first wave of the pandemic may have been particularly infectious because the most common first symptom was likely a cough, according to a study led by researchers from the USC Dornsife College of Letters, Arts and Science. The study suggests that people infected with what was the world’s most infectious strain of COVID-19 in May 2020, and the most dominant strain in the U.S. two months later, were likely to experience a cough as their first symptom, followed by fever. The research was conducted at the USC Michelson Center for Convergent Bioscience in the Convergent Science Institute in Cancer led by Peter Kuhn. The greater transmissibility of that variant — D614G — might be explained by infected individuals coughing and spreading the virus before they were incapacitated by fever. COVID-19 is most commonly spread through respiratory droplets, often amplified by a cough of symptomatic patients. Conversely, those infected with the COVID-19 variant during the initial outbreak in China, the Wuhan reference strain, probably experienced fever as their first symptom, followed by cough. Studying the likely order of symptoms, in addition to how the disease spreads, can inform additional research and health care about how people experience the disease. The study, which was published today (December 16, 2021) by PLOS Computational Biology, also noted that: In Japan, it’s likely a fever was the initial symptom when the Wuhan reference strain was dominant there. When the D614G variant supplanted it, a cough was likely the first symptom. This finding validates similar results from other geographical regions and supports the hypothesis that a cough occurs earlier in the D614G variant than the Wuhan reference strain. The predicted symptom order was not altered by region, weather, patient age, or comorbidity. The study did not answer the question of whether the order of symptoms found in the initial waves of the pandemic holds true for current variants. Expert Analysis “With the emergence of new variants and the likelihood COVID-19 becomes endemic in the population, it’s important that researchers continue to show how viral variants affect the progression of symptoms and disease in individuals and populations.” Peter Kuhn, a dean’s professor of biological sciences and professor of biological sciences, medicine, biomedical engineering and aerospace and mechanical engineering. “Studying the likely order of symptoms may increase our understanding of how disease spreads and further inform future research and health care on how individuals are likely to experience disease.” Joseph Larsen, graduate researcher at USC’s Convergent Science Institute of Cancer and doctoral candidate in USC Dornsife’s Quantitative and Computational Biology Department. Background The latest findings expand on research that Kuhn and his collaborators published in August 2020 that discovered the order of symptoms from the Wuhan reference strain. The discovery was based on a mathematical model using data from an outbreak in China in early 2020. Reference: “Modeling the onset of symptoms of COVID-19: Effects of SARS-CoV-2 variant” by Joseph R. Larsen, Margaret R. Martin, John D. Martin, James B. Hicks and Peter Kuhn, 16 December 2021, PLoS Computational Biology. DOI: 10.1371/journal.pcbi.1009629 About the study In addition to Kuhn and Larsen, study co-authors from USC Dornsife were James B. Hicks, professor (research) of biological sciences. Kuhn, Hicks and Larsen are also associated with the USC Michelson Center for Convergent Bioscience. Additional authors were Margaret Martin from Tufts University’s Department of Computer Science and John Martin at Materia Therapeutics. Funding support came from the Hsieh Family Foundation and the Kathy & Richard Leventhal Research Fund. Larsen also had support from USC Dornsife and the Schlegel Family Endowment Fellowship. About USC Dornsife The USC Dornsife College of Letters, Arts and Sciences is the oldest school at the University of Southern California and works across the natural sciences, social sciences and humanities, exploring fundamental questions about who we are, how the world works, and what we can do to improve and enrich society. About the USC Michelson Center The USC Michelson Center for Convergent Bioscience was created to accelerate discoveries from the bench to the bedside. The physical hub of this effort is Michelson Hall, a state-of-the-art research building housing cutting edge technology platforms and the nucleus of various research programs. The Michelson Center includes researchers from USC Dornsife, the USC Viterbi School of Engineering, the Keck School of Medicine of USC, as well as the USC School of Cinematic Arts and the Information Sciences Institute.

Baleen whale feeding. Scientists from UNSW Sydney have uncovered the secrets locked in the jawlines of humpback and southern right whales. Baleen plates – the signature bristle-like apparatus toothless whales use to feed – reveal how these large aquatic mammals adapt to environmental changes over time. Baleen from filter-feeding whales – that is, the bristle-like structures toothless whales like the humpback and southern rights rely on to feed – holds a chemical record of their feeding patterns, which can help researchers understand changes in the whales’ movements and behaviors over time. Researchers have now shown how the changes in the dietary habits of whales going back almost 60 years correspond with changing climate cycles. The research, published in Frontiers in Marine Science, shows it’s possible to link feeding patterns with climate conditions using whale baleen, which could help us understand how these large aquatic mammals may react to climate events in the future. “What is incredible is that all of this information about dietary and spatial patterns has been unlocked just through analyzing plates in their mouths,” says Adelaide Dedden, the lead author of the study and a PhD candidate at UNSW Science. In the study, the researchers compared the information stored in the baleen of humpback and right whales in the Pacific and Indian Ocean with environmental data to see whether their behaviors reflected changes in climate conditions over time. “We found that the same conditions – the La Niña events – that bring us these devastating floods are also not good for the humpbacks that migrate along the east coast of Australia,” says UNSW Professor Tracey Rogers, marine ecologist and senior author of the study. Baleen plates. Using baleen samples from museum archives, strandings, and previously published data from other studies they discovered humpback whales migrating along the east coast of Australia showed signs of poorer feeding opportunities during La Niña phases – a large-scale climate cycle that drives food availability within the Southern Ocean. “Baleen whales are enormous and need huge amounts of food. This makes them vulnerable to changes in the environment, but this is also compounded by their survival strategy,” Prof. Rogers says. “They fast for the long periods when they leave their productive feeding grounds to breed. That’s why they’re extremely susceptible to changes in ocean-atmospheric cycles as they can drive food availability.” Whalebone Whispers An animal the size of a whale isn’t exactly easy to analyze in a lab environment. Instead, researchers can look at smaller hard tissues that keep a more detailed record of the animal’s activity. For filter-feeding whales, the long, slender keratin plates that hang from their upper jaw known as baleen allow them to take in many small prey at one time – but they also lay down chemical clues known as stable isotopes that give clues about their eating habits. “As the baleen grows, biochemical signals from their food are trapped. Like the information on the pages in a book, they don’t change with time,” says Prof. Rogers. “These signals allow us to reconstruct the behavior of the whales through time – what they ate, and the general area they were at the time.” The study found that the variability in the stable isotopes within baleen for the humpbacks matched the changes in climate cycles – implying that the whales’ feeding patterns change with climate-driven resource availability. “Oscillation patterns in isotopes assimilated along their baleen plates are known to reflect changes in the whale’s physiology, but we also found links between this isotope variability and changes in the environment happening at the time,” Ms. Dedden says. Feast or Famine Humpbacks spend their winter months in warm tropical waters to breed before traveling back to southern Antarctic waters during summer to feed. Amid this migration to the tropics, they’re away from reliable food sources and must depend on their body’s reserves and opportunistic prey off Australia to survive. “As filter feeders, they rely on big aggregations of krill because it is energetically costly for them to feed,” Ms. Dedden says. Antarctic krill need sea ice to thrive. Following La Niña phases, other research has found there is less sea ice concentration where these whales feed, meaning there are fewer krill for whales to consume and sustain them through their migration months. “[With] humpbacks from the east coast of Australia showing signs of reduced feeding following La Niña periods, it means they’re potentially struggling to build up the energy reserves required during summer,” Ms. Dedden says. Previous research found links between increased whale strandings on the Australian coast following La Niña years, which the researchers say can be attributed to less feeding success. “Our colleagues have shown humpbacks are leaner – a sign they’re experiencing poor feeding conditions – and have a higher chance of stranding in the years following La Niña events,” Prof. Rogers says. “With La Niña events predicted to increase in intensity and frequency, it unfortunately means these whales may continue to have more of these poorer feeding prospects, and we could see more strandings in the future.” Hopes for the Future While it’s not clear waters for east coast humpbacks, the study found that humpbacks from the west coast of Australia who feed in the Indian Ocean showed increased feeding success during La Niña periods. In promising signs, the researchers also say their counterparts on the east coast are developing alternative feeding strategies in more temperate waters. “East coast humpbacks have shown signs of adapting to different feeding strategies in other known productive regions on their migration route…something that future research could look at,” Ms. Dedden says. The researchers hope to use the study’s findings to develop models that can help predict whale behavior in the future. “We’ve worked out patterns from the historical trends from the past, and now we can use those models to make predictions into the future to see what it might look like for our whales,” Prof. Rogers says. “The information from the study will also be useful for managers now, to know ahead of time those years whales are likely to be more vulnerable so they can be prepared and, if needed, change their management strategies around whale entanglement and stranding.” While humpback whales are no longer listed as endangered, climate change still poses a significant long-term threat to the species. Prof. Rogers says our actions today to address climate change will make a big difference for whale populations now and in the future, just like they will for us. “We need to act now while we still can,” she says. “Acting on climate change now is good for whales but also for all of us.” Reference: “Stable Isotope Oscillations in Whale Baleen Are Linked to Climate Cycles, Which May Reflect Changes in Feeding for Humpback and Southern Right Whales in the Southern Hemisphere” by Adelaide V. Dedden and Tracey L. Rogers, 21 March 2022, Frontiers in Marine Science. DOI: 10.3389/fmars.2022.832075

Johns Hopkins University researchers highlight the potential of multispectral photoacoustic imaging in preventing nerve injuries during invasive medical procedures, identifying key wavelengths for optimal nerve visualization. Scientists investigate the unique absorption spectra of myelinated nerves as a way to visualize and differentiate them from their surroundings. Invasive medical procedures, such as surgery requiring local anesthesia, often involve the risk of nerve injury. During an operation, surgeons may accidentally cut, stretch, or compress nerves, especially when mistaking them for some other tissue. This can lead to long-lasting symptoms in the patient, including sensory and motor problems. Similarly, patients receiving nerve blockades or other types of anesthesia can suffer from nerve damage if the needle is not placed at the correct distance from the targeted peripheral nerve. Challenges in Current Imaging Techniques Consequently, researchers have been trying to develop medical imaging techniques to mitigate the risk of nerve damage. For instance, ultrasound and magnetic resonance imaging (MRI) can help a surgeon pinpoint the location of the nerves during a procedure. However, it is challenging to tell the nerves apart from surrounding tissue in ultrasound images, while MRI is expensive and time-consuming. Photoacoustic images of the ulnar (left) and median (right) nerves from a swine recorded in vivo for the first time. The nerves were illuminated with 1725 nm light and overlaid on co-registered ultrasound images. The outlines of the nerves and the surrounding agarose regions of interest (ROI) are shown as well. Credit: M. Graham et al., doi 10.1117/1.JBO.28.9.097001 The Promise of Photoacoustic Imaging In this regard, there is a promising alternative approach known as multispectral photoacoustic imaging. A noninvasive technique, photoacoustic imaging combines light and sound waves to create detailed images of tissues and structures in the body. Essentially, the target region is first illuminated with pulsed light, causing it to heat up slightly. This, in turn, causes the tissues to expand, sending out ultrasonic waves that can be picked up by an ultrasound detector. Recent Research from Johns Hopkins University A research team from Johns Hopkins University recently conducted a study in which they thoroughly characterized the absorption and photoacoustic profiles of nerve tissue across the near-infrared (NIR) spectrum. Their work, published on September 4 in the Journal of Biomedical Optics, was led by Dr. Muyinatu A. Lediju Bell, John C. Malone Associate Professor and PULSE Lab Director at Johns Hopkins University. One of the main objectives of their study was to determine the ideal wavelengths for identifying nerve tissue in photoacoustic images. The researchers hypothesized that the wavelengths from 1630–1850 nm, which reside within the NIR-III optical window, would be the optimal range for nerve visualization, since the lipids found in the myelin sheath of neurons have a characteristic absorption peak in this range. To test this hypothesis, they performed detailed optical absorption measurements on peripheral nerve samples. They observed an absorbance peak at 1210 nm, which fell in the NIR-II range. However, such an absorption peak is also present in other types of lipids. In contrast, when the contribution of water was subtracted from the absorbance spectrum, nerve tissue exhibited a unique peak at 1725 nm in the NIR-III range. Practical Testing and Implications Additionally, the researchers conducted photoacoustic measurements on the peripheral nerves of live swine using a custom imaging setup. These experiments further confirmed the hypothesis that the peak in the NIR-III band can be effectively leveraged to differentiate lipid-rich nerve tissue from other types of tissues and materials containing water or that are lipid-deficient. Satisfied with the results, Bell remarks: “Our work is the first to characterize the optical absorbance spectra of fresh swine nerve samples using a wide spectrum of wavelengths, as well as the first to demonstrate in-vivo visualization of healthy and regenerated swine nerves with multispectral photoacoustic imaging in the NIR-III window.” Overall, these findings could motivate scientists to further explore the potential of photoacoustic imaging. Moreover, the characterization of the optical absorbance profile of nerve tissue could help improve nerve detection and segmentation techniques when using other optical imaging modalities. “Our results highlight the clinical promise of multispectral photoacoustic imaging as an intraoperative technique for determining the presence of myelinated nerves or preventing nerve injury during medical interventions, with possible implications for other optics-based technologies. Our contributions thus successfully establish a new scientific foundation for the biomedical optics community,” concludes Bell. Reference: “Optical absorption spectra and corresponding in vivo photoacoustic visualization of exposed peripheral nerves” by Michelle T. Graham, Arunima Sharma, William M. Padovano, Visakha Suresh, Arlene Chiu, Susanna M. Thon, Sami Tuffaha and Muyinatu A. Lediju Bell, 4 September 2023, Journal of Biomedical Optics. DOI: 10.1117/1.JBO.28.9.097001

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