Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Innovative pillow ODM production solution in Taiwan

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Taiwan OEM/ODM hybrid insole development factory

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Custom graphene foam processing factory Taiwan

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Vietnam ODM expert for comfort products

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Indonesia anti-bacterial pillow ODM design

Researchers have discovered that meerkats use two distinct types of vocalizations to communicate: ‘close calls’ for interactive exchanges and ‘short notes’ for broadcasting their presence without expecting a response. These findings, derived from synchronized audio and GPS data, highlight the importance of vocal communication in maintaining group cohesion and safety among meerkats. Credit: Vlad Demartsev Meerkats use two distinct types of vocal interactions to maintain communication with their group mates. Sometimes their calls simply convey information, while other times, meerkats engage in a call exchange with their neighbors. This behavior was detailed in a recent study conducted by researchers from the Centre for the Advanced Study of Collective Behaviour at the University of Konstanz and the Max Planck Institute of Animal Behavior. Their findings were published recently in the biological sciences. journal Philosophical Transactions of the Royal Society B. Vocal interactions play a critical role in maintaining group cohesion, which is essential for survival as meerkats are more vulnerable when isolated. Credit: Vlad Demartsev Continuous Communication Meerkats, which are group-living animals, are almost constantly on the move throughout the day. As they are walking or running, they make a continuous series of noises. Researchers have decoded how wild meerkats utilize two of these sounds. “The first sound, a ‘close call’, is like a call-and-response exchange between the animals. When one meerkat calls, a neighbor is likely to reply,” explains Vlad Demartsev, a postdoctoral researcher from the Cluster of Excellence Collective Behaviour. “Whereas the second call, named a ‘short note’, announces ‘I am here’ but doesn’t necessarily get a direct reply from communication partners.” Meerkats are highly social animals and live in groups of up to 50 members. Credit: Vlad Demartsev Quiz question: Listen to the two calls. Which call do you think will get a reply from a neighbor? “When one meerkat calls, a neighbor is likely to reply.” What kind of sound are we talking about? The first call. The second call, known as the ‘short note’, announces ‘I am here’, but does not necessarily receive a direct response from the communication partners. As they forage and explore, meerkats emit a continuous series of calls, ensuring that no member becomes separated from the group. Credit: Vlad Demartsev Vocal Interactions: Exchange vs. Broadcast Consider an announcement in front of a large crowd where the flow of information is mostly one-way, with no real exchange between the speaker and the audience. “It is impossible to hold a conversation with 20 people, so we normally talk to one partner at a time,” explains Demartsev. Close calls are such an exchange between communication partners and short notes are more like a broadcast or an announcement aimed at the whole group. The ‘short note’ is used by meerkats to announce their presence but doesn’t necessarily elicit a direct reply from others. Credit: Vlad Demartsev Research Methodology Demartsev, along with Ariana Strandburg-Peshkin and collaborators from the University of Zurich, equipped several groups of meerkats with collars at the Kalahari Research Centre in South Africa. The collars recorded continuous audio data and GPS positions were sampled every second. Using these collars, the researchers got a synchronized recording and could see which animal produced which sound at which time and where. Researchers used collars that recorded audio and GPS data to track the origin of each sound, identifying the specific meerkat making the call, their location, and the timing of the sound. Credit: Vlad Demartsev Analysis of Vocal Interactions The researchers prepared a vocal timeline for the entire group and analyzed the data. “We saw that when a close call is given, there is a very high probability that within less than half a second a nearby neighbor will respond. But when we have a short note, we do not have this pattern. All of them are calling nearly at the same time and there is no structure,” says Demartsev. Strandburg-Peshkin adds, “Ultimately, calls are not just single isolated events, but a continuous stream of communication between group members. So, looking at the temporal structure of the interactions can help us to better understand how calls are used and what their function is.” Group cohesion is critical for meerkats because isolation increases their risk of predation or harassment by other groups, highlighting the importance of their communication system. Credit: Vlad Demartsev The Importance of Group Cohesion Staying in a group is crucial for meerkats and they use multiple mechanisms that evolved to avoid getting separated. “When meerkats are by themselves there is a higher chance of predation or harassment by other groups. Generally, meerkats therefore try very, very hard to stay together,” says Demartsev. Reference: “Mapping vocal interactions in space and time differentiates signal broadcast versus signal exchange in meerkat groups” by Vlad Demartsev, Baptiste Averly, Lily Johnson-Ulrich, Vivek H. Sridhar, Leonardos Leonardos, Alexander Q. Vining, Mara Thomas, Marta B. Manser and Ariana Strandburg-Peshkin, 1 May 2024, Philosophical Transactions B. DOI: 10.1098/rstb.2023.0188

A new study uncovers that a growth factor, epiregulin, significantly contributes to the expansion of the human neocortex, enhancing our comprehension of what makes humans unique in cognitive functions. What makes us human? According to neurobiologists, it is our neocortex. This outer layer of the brain is rich in neurons and lets us do abstract thinking, create art, and speak complex languages. An international team led by Dr. Mareike Albert at the Center for Regenerative Therapies Dresden (CRTD) of TUD Dresden University of Technology has identified a new factor that might have contributed to neocortex expansion in humans. The results were published in the EMBO Journal. The neocortex is the characteristic folded outer layer of the brain that resembles a walnut. It is responsible for higher cognitive functions such as abstract thinking, art, and language. “The neocortex is the most recently evolved part of the brain,” says Dr. Mareike Albert, research group leader at the CRTD. “All mammals have a neocortex, but it varies in size and complexity. Human and primate neocortices have folds while, for example, mice have a completely smooth neocortex, without any creases.” The folds characteristic of the human brain increase the surface area of the neocortex. The human neocortex has a greater number of neurons that support complex cognitive functions. The molecular mechanisms driving neocortex evolution are still largely unknown. “Which genes are responsible for inter-species differences in neocortex size? What factors have contributed to brain expansion in humans? Answering these questions is crucial to understanding human brain development and potentially addressing mental health disorders,” explains Dr. Albert. The Power of Brain Organoids To search for factors influencing brain expansion, the Albert group compared the developing brains of mice and humans. “Stem cells in mice don’t divide as much and don’t produce as many neurons compared to primates. Humans, on the other hand, have a large number of stem cells in the developing brain. This highly expanded pool of stem cells underlies the increase in the number of neurons and brain size,” explains Dr. Albert. A microscopy image of a human brain organoid. Credit: Janine Hoffmann The team found a factor that is present in humans but not in mice. Using 3D cell culture technology, the group tested if the newly identified factor could influence the expansion of the neocortex. “Thanks to the research awarded with the Nobel prize in 2012, it is possible to turn any cell into a stem cell. Such a stem cell can then be transformed into a three-dimensional tissue that resembles an organ, e.g., a brain. Human stem cells make it possible to study development and diseases directly in human tissues,” explains Dr. Albert. These 3D brain cultures, or brain organoids, may not resemble brains to an untrained eye, but they mimic the cellular complexity of developing brains. “Most of the cell types of the developing brain are present. They interact, signal, and are similarly arranged as in an actual human brain,” says Dr. Albert. Using 3D brain organoids, the group was able to show that a growth factor, known as epiregulin, indeed promotes the division and expansion of stem cells in the developing brain. All About the Amount “Knowing that epiregulin drives expansion of human neocortical stem cells, we looked back at the gene that codes for epiregulin and tried to trace it through the evolutionary tree,” says study lead author Paula Cubillos, a doctoral candidate at the CRTD. The gene is not unique to humans, but also present in other primates and even in mice. “Epiregulin is not produced in the developing mouse brain, however, because the gene is permanently shut off and not being used. We were intrigued to understand whether there are any differences in how epiregulin works in humans and other primates,” explains Paula Cubillos. The researchers turned again to the 3D culture technology. Using gorilla stem cells, the researchers generated gorilla brain organoids. “Gorillas are endangered species. We know very little about their brain development. Organoids made from stem cells offer a way to study their brain development without interacting with the species at all,” says Dr. Albert. Comparing the effect of epiregulin in human and gorilla brain organoids, the team found that adding epiregulin to gorilla brain organoids can further promote the expansion of stem cells. However, adding even more epiregulin to human brain organoids did not have the same effect. This might be because the human neocortex has already expanded to a very large extent. “Unlike previously identified factors, epiregulin as such seems not to be unique to humans. Instead, the amount of the growth factor seems to be the crucial regulator for the inter-species differences,” concludes Dr. Albert. This study not only advances our understanding of human uniqueness but also highlights the importance of new technologies that offer ethical and non-invasive complements to animal research. Reference: “The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex” by Paula Cubillos, Nora Ditzer, Annika Kolodziejczyk, Gustav Schwenk, Janine Hoffmann, Theresa M Schütze, Razvan P Derihaci, Cahit Birdir, Johannes EM Köllner, Andreas Petzold, Mihail Sarov, Ulrich Martin, Katherine R Long, Pauline Wimberger and Mareike Albert, 21 March 2024, The EMBO Journal. DOI: 10.1038/s44318-024-00068-7 The study was performed in collaboration with King’s College London, the Medical Faculty Carl Gustav Carus of TU Dresden, the Max Planck Institute of Molecular Cell Biology and Genetics, and Hannover Medical School.

A black bear eats hawthorn berries. Large animals can disperse seeds over great distances, but many large seed dispersers are extinct or in decline. Credit: Photo by Paul D. Vitucci When Given the Option, Captive Bears Mimic the Diverse Diets of Their Wild Counterparts Bears are neither cats nor dogs, and feeding them as such is probably going to make them live shorter lifetimes. A recent study published in the journal Scientific Reports on the diets of giant pandas and sloth bears provides additional proof that bears are omnivores like humans and need a lot less protein than they are given in zoos. “Bears are not carnivores in the strictest sense like a cat where they consume a high-protein diet,” said lead author Charles Robbins, a Washington State University wildlife biology professor. “In zoos forever, whether it’s polar bears, brown bears, or sloth bears, the recommendation has been to feed them as if they are high-protein carnivores. When you do that, you kill them slowly.” In separate tests, scientists fed captive giant pandas and sloth bears an unlimited range of foods to observe their preferences before recording the nutritional profiles of their selections. Giant Pandas’ Bamboo Preference To gauge the giant pandas’ preference for bamboo, feeding studies with a pair of the animals were carried out in partnership with scientists from Texas A&M University and the Memphis Zoo. They discovered that giant pandas preferred the higher protein- and carbohydrate-rich bamboo culm found in the woody stalks to the leaves. They sometimes consumed culm almost exclusively; for example, 98% of the time in March. The researchers also examined data from five Chinese zoos that housed giant pandas that had successfully given birth to offspring and discovered that they thrived on a diet heavy in carbohydrates and low in protein. In sets of feeding trials, six sloth bears at the Cleveland, Little Rock, and San Diego zoos were presented with unlimited avocados, baked yams, whey, and apples. They chose the fat-rich avocados almost exclusively, eating roughly 88% avocadoes to 12% yams – and ignoring the apples altogether. This showed sloth bears preferred a high-fat, low-carbohydrate diet, which may have a similar makeup to their wild diet of termites and ants as well as their eggs and larvae. Captive Bears’ Diets and Lifespan It’s also vastly different than the high-carbohydrate diet they are usually fed in captivity. Sloth bears, which are native to India, typically live only around 17 years in U.S. zoos, almost 20 years less than the maximum lifespan achievable in human care. Their most frequent cause of death is liver cancer. Researchers saw a similar pattern in previous studies of polar bears that showed captive polar bears, who are normally fed a high-protein diet, would mimic the fat-rich diet of wild polar bears if given the option. Polar bears in zoos typically die about 10 years earlier than they should, most often of kidney and liver disease. These two diseases can develop from long-term inflammation of those organs, potentially caused by many years of poorly balanced diets. The current study, along with previous ones, also shows that when captive bears are given dietary options, they will choose foods that imitate the diets of wild bears. “There’s certainly this long-standing idea that humans with Ph.D.s know a lot more than a sloth bear or a brown bear,” said Robbins. “All of these bears started evolving about 50 million years ago, and in terms of this aspect of their diet, they know more about it than we do. We’re one of the first to be willing to ask the bears: What do you want to eat? What makes you feel well?” Bear Evolution and Nutrition Robbins, the founder of the WSU Bear Center, the only research institution in the U.S. with a captive population of grizzlies, has studied bear nutrition for decades. He and his graduate students first started investigating their misbalanced diets during a study in Alaska, watching grizzlies eat salmon. At the time, the researchers had theorized that the notoriously voracious bears would gorge on salmon, sleep, get up and eat more salmon. Instead, they saw the bears would eat salmon, but then wander off and spend hours finding and eating small berries. Seeing that, Robbins’ laboratory started investigating the diet of the grizzly bears housed at the Bear Center and found they gained the most weight when fed a combination of protein, fats, and carbohydrates in the combination of salmon and berries. All eight types of bears, or Ursids, had a carnivore ancestor but have since evolved to eat a wide array of food, which gave them the ability to spread into more areas by not directly competing with resident carnivores. “It just opens up so many more food resources than just being a straight, high protein carnivore,” Robbins said. Reference: “Ursids evolved early and continuously to be low-protein macronutrient omnivores” by Charles T. Robbins, Amelia L. Christian, Travis G. Vineyard, Debbie Thompson, Katrina K. Knott, Troy N. Tollefson, Andrea L. Fidgett and Tryon A. Wickersham, 9 September 2022, Scientific Reports. DOI: 10.1038/s41598-022-19742-z The study was funded by the U.S. Department of Agriculture.

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