Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Vietnam pillow ODM development service

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Thailand ergonomic pillow OEM supplier

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Custom foam pillow OEM in China

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Latex pillow OEM production in Thailand

The injected green algae (green) sit inside the blood vessels (magenta) like a string of pearls. Credit: Özugur et al./iScience Photosynthesizing algae injected into the blood vessels of tadpoles supply oxygen to their brains. Leading a double life in water and on land, frogs have many breathing techniques – through the gills, lungs, and skin – over the course of their lifetime. Now German scientists have developed another method that allows tadpoles to “breathe” by introducing algae into their bloodstream to supply oxygen. The method developed, presented October 13 in the journal iScience, provided enough oxygen to effectively rescue neurons in the brains of oxygen-deprived tadpoles. “The algae actually produced so much oxygen that they could bring the nerve cells back to life, if you will,” says senior author Hans Straka of Ludwig-Maximilians-University Munich. “For many people, it sounds like science fiction, but after all, it’s just the right combination of biological schemes and biological principles.” Straka was studying oxygen consumption in tadpole brains of African clawed frogs (Xenopus laevis) when a lunch conversation with a botanist sparked an idea to combine plant physiology with neuroscience: harnessing the power of photosynthesis to supply nerve cells with oxygen. The idea didn’t seem far-fetched. In nature, algae live harmoniously in sponges, corals, and anemones, providing them with oxygen and even nutrients. Why not in vertebrates like frogs? As German researchers inject green algae into a beating tadpole heart, the translucent animal’s veins gradually turn green. Upon illumination, the algae can produce oxygen. Credit: Özugur et al./iScience To explore the possibility, the team injected green algae (Chlamydomonas renhardtii) or cyanobacteria (Synechocystis) into tadpoles’ hearts. With each heartbeat, the algae inched through blood vessels and eventually reached the brain, turning the translucent tadpole bright green. Shining light on these tadpoles prompted both algae species to pump out oxygen to nearby cells. After distributing algae to the brain, the researchers isolated the tadpole’s head and placed it in an oxygen bubble bath with essential nutrients that would preserve the functioning of the cells, allowing the team to monitor neural activity and oxygen levels. As the researchers depleted oxygen from the bath, the nerves ceased firing and fell silent. However, illuminating the tadpole head restarted the neural activity within 15 to 20 minutes, which is about two times faster than replenishing the bath with oxygen without the algae. The revived nerves also performed as well or even better than before oxygen depletion, showing that the researchers’ method was quick and efficient. “We succeeded in showing the proof of principle experiment with this method. It was amazingly reliable and robust, and in my eyes, a beautiful approach,” says Straka. “Working in principle doesn’t really mean that you could apply it at the end, but it’s the first step in order to initiate other studies.” While the researchers think their findings may someday lead to new therapies for conditions induced by stroke or oxygen-scarce environments, such as underwater and high altitudes, algae are far from ready to enter our blood circulation. The team’s next step is to see whether the injected algae can survive inside living tadpoles and continue oxygen production without causing an immune response that wreaks havoc on the animals. Straka also envisions his research benefiting other laboratories that work with isolated tissues or organoids. Introducing oxygen-producing algae could help these tissues thrive and raise their survival rates, potentially reducing the need for live animals for experiments. “You have to have new ideas and new concepts to explore; this is one of the ways science is driven,” says Straka. “If you are open-minded and think it through, all of a sudden, you can see all the possibilities from one idea.” Reference: “Green oxygen power plants in the brain rescue neuronal activity” by Suzan Özugur, Myra N. Chávez, Rosario Sanchez-Gonzalez, Lars Kunz, Jörg Nickelsen and Hans Straka, 13 October 2021, iScience. DOI: 10.1016/j.isci.2021.103158 This work was supported by German Science Foundation, the German Federal Ministry of Education and Research, and the Munich Center for Neuroscience.

A sample of a macroalga collected by researchers to study the presence of Ostreopsis microalgae. Credit: Aner Etxebarria The spread of the Ostreopsis ovata algae is not a cause for concern, but ongoing monitoring is recommended, according to Laurenns Balparda, a researcher at the University of the Basque Country (UPV/EHU). Ostreopsis is a microscopic alga that thrives in shallow waters. Certain species produce toxins that can cause symptoms such as coughing, fever, skin irritation, and mild respiratory issues. Originally native to tropical regions, rising ocean temperatures have expanded their suitable habitats, including the Basque coast. In the Bay of Biscay, Ostreopsis was first detected in 2007. Initially, its presence was sporadic, but in recent years, large blooms have become common along the coastline during summer. While these blooms do not always pose a threat, the first recorded cases of poisoning occurred in Lapurdi-Labourd in 2020, followed by Donostia/San Sebastián in 2021. In this context, a team from the UPV/EHU’s phytoplankton laboratory studied the proliferation of Ostreopsis in La Concha Bay: “We analyzed their presence in two locations: in the west of Ondarreta and in the east of La Concha. The aim was to find out about their development in both locations and to detect the factors that led to the huge growth of the microalgae in Donostia,” explained the researcher Yago Laurenns-Balparda. The study revealed that Ostreopsis is more abundant in Ondarreta and its authors concluded that this is due to the type of substrate: “The two locations where we took samples are quite similar in terms of temperature, current, wind, and salinity. What distinguishes them is the substrate: the seabed of Ondarreta is completely covered by rocks of varying sizes where there is a large amount of macroalgae, which is one of the favorite places for Ostreopsis to grow. By contrast, almost the entire seabed of La Concha is sand; there are few rocks or macroalgae. So, the substrate does not encourage the development of Ostreopsis.” Laurenns-Balparda pointed out that the fact that this microalga is abundant on our coasts does not mean that bathing from these beaches is always dangerous: “In fact, even though the samples collected in the summers of 2022 and 2023 indicated a massive presence of Ostreopsis in La Concha Bay, no cases of poisoning were recorded on the beaches of Donostia during those years. It is advisable to continue taking measurements to find out the level of concentration of these algae and to keep the situation under control, but their abundance is not always a cause for alarm. Just because there is a lot of Ostreopsis doesn’t mean that toxicity is high.” Presence of potentially toxic species ovata confirmed for the first time in La Concha Bay Besides corroborating the importance of the type of substrate as a determining factor in encouraging the massive growth of Ostreopsis, the research carried out by the UPV/EHU has served to confirm that, of the thirteen species that exist, the toxic ovata is present in La Concha Bay. This is something new, given that until now only research in which the harmless species Siamensis was detected has been published. Laurenns-Balparda pointed out that “in the past, it could be assumed or taken for granted that ovata was also present because it is a priori the only toxic species of Ostreopsis. However, it could not be confirmed. Our study was the first to prove it.” Even so, there are still questions to be answered, since although the study showed that Siamensis and Ovata coexist in La Concha and Ondarreta, it was not able to determine the proportion in which each of the species is present: “We weren’t able to do this because they are very similar to each other and cannot be differentiated even under a microscope. However, thanks to molecular studies, we did manage to confirm that many of the strains of cells that we isolated from the samples collected on the beaches were ovata, but these analyses do not allow us to know which of the two species is more abundant,” explained Laurenns-Balparda. The UPV/EHU biologist emphasizes the importance of conducting further research to gain a better understanding of the dynamics of these microalgae, “to get more comprehensive knowledge about what other factors may affect their growth and toxicity, and to be able to implement some technology that will help to determine which species predominates.” Reference: “Summer Ostreopsis blooms in San Sebastian (South-East Bay of Biscay): The importance of substrate features” by Yago Laurenns-Balparda and Sergio Seoane, 21 December 2024, Marine Pollution Bulletin. DOI: 10.1016/j.marpolbul.2024.117484

The perplexing phenomenon of homochirality in life, where biomolecules exist in only one of two mirror-image forms, remains unexplained despite historical attention from scientific figures like Pasteur, Lord Kelvin, and Pierre Curie. Recent research suggests the combination of electric and magnetic fields might influence this preference through experiments showing enantioselective effects on chiral molecules interacting with magnetized surfaces, offering indirect evidence towards understanding this mystery. The phenomenon known as homochirality of life, which refers to the exclusive presence of biomolecules in one of their two possible mirror-image configurations within living organisms, has intrigued several prominent figures in science. This includes Louis Pasteur, who first identified molecular chirality, William Thomson (also known as Lord Kelvin), and Pierre Curie, a Nobel Laureate. A conclusive explanation is still lacking, as both forms have, for instance, the same chemical stability and do not differ from each other in their physicochemical properties. The hypothesis, however, that the interplay between electric and magnetic fields could explain the preference for one or the other mirror-image form of a molecule – so-called enantiomers – emerged early on. It was only a few years ago, though, that the first indirect evidence emerged that the various combinations of these force fields can indeed “distinguish” between the two mirror images of a molecule. This was achieved by studying the interaction of chiral molecules with metallic surfaces that exhibit a strong electric field over short distances. If only left-handed helicene spirals are deposited on the cobalt-copper surface, they clearly prefer cobalt islands with a certain direction of magnetization. In the image, the two triangular cobalt islands have opposite magnetization; the left-handed helicene molecules bind almost exclusively to the island on the right and avoid the island on the left (except for a few molecules at the edge of the island). Credit: Peter Grünberg Institute/Jülich The surfaces of magnetic metals such as iron, cobalt, or nickel thus allow electric and magnetic fields to be combined in various ways – the direction of magnetization is simply reversed, from “North up – South down” to “South up – North down”. If the interplay between magnetism and electric fields actually triggers “enantioselective” effects, then the strength of the interaction between chiral molecules and magnetic surfaces should also differ, for example – depending on whether a right-handed or left-handed molecule “settles” on the surface. Mirror images prefer opposing magnetic fields And this is indeed the case, as a team of researchers led by Karl-Heinz Ernst from the Empa’s Surface Science and Coating Technologies lab and colleagues at the Peter Grünberg Institute at the Forschungszentrum Jülich in Germany recently reported in the scientific journal Advanced Materials. The team coated a (non-magnetic) copper surface with small, ultra-thin “islands” of magnetic cobalt and determined the direction of the magnetic field in these using spin-polarized scanning tunneling microscopy; as mentioned before, this can run in two different directions perpendicular to the metal surface: North up or South up. They then deposited spiral-shaped chiral molecules – a 1:1 mixture of left- and right-handed heptahelicene molecules – onto these cobalt islands in an ultrahigh vacuum. Then they “simply” counted the number of right- and left-handed helicene molecules on the differently magnetized cobalt islands, almost 800 molecules in total, again using scanning tunneling microscopy. And lo and behold: Depending on the direction of magnetic field, one or the other form of the helicene spirals had settled preferentially (see right side of the graphic). This is how chirality-induced spin selectivity (CISS effect) manifests itself: Electrons (e– or red and green spheres with arrows indicating electron spin, either up or down) with the “wrong” direction of rotation (spin) are held back or filtered out when tunneling through spiral molecules, depending on the handedness of the spirals (left- or right-handed), so that one type of electron spin predominates (electrons with the arrow pointing downwards on the left side). The electric field of a metallic surface (E, pointing upwards, right side) shifts the electrons in the bound heptahelical molecules; these accumulate slightly in the lower part of the molecule near the surface. In the case of chiral molecules, electrons with different spins are also shifted differently depending on the handedness of the molecule. The molecule becomes “spin-polarized”, i.e. also magnetic. Depending on the direction of magnetization of the metallic surface, chiral molecules therefore interact with it to different degrees. In this example, the purple spiral therefore binds more strongly to the surface than the yellow one, as opposite spins “attract” each other (the red and green electrons with different spins sitting on top of each other). Credit: Empa Moreover, the experiments showed that the selection – the preference for one or the other enantiomer – not only occurs during the binding on the cobalt islands, but already beforehand. Before the molecules take up their final (preferred) position on one of the cobalt islands, they migrate long distances across the copper surface in a significantly weaker bound precursor state in “search” for an ideal position. They are only bound to the surface by so-called van der Waals forces. These are merely caused by fluctuations in the electronic shell of atoms and molecules and are therefore relatively weak. The fact that even these are influenced by magnetism, i.e. the direction of rotation (spin) of the electrons, was not known thus far. Electrons with the “wrong” spin are filtered out Using scanning tunneling microscopy, the researchers were also able to solve another mystery, as they reported in the journal Small last November. Electron transport – i.e. electric current – also depends on the combination of molecular handedness and magnetization of the surface. Depending on the handedness of the bound molecule, electrons with one direction of spin preferentially flow – or “tunnel” – through the molecule, meaning that electrons with the “wrong” spin are filtered out. This chirality-induced spin selectivity (CISS effect, see left side of the graphic) had already been observed in earlier studies, but it remained unclear whether an ensemble of molecules is necessary for this or whether individual molecules also exhibit this effect. Ernst and his colleagues have now been able to show that individual helicene molecules also exhibit the CISS effect. “But the physics behind this is still not understood,” admits Ernst. The Empa researcher also believes that his findings eventually cannot fully answer the question of the chirality of life. In other words, the question that the Nobel Prize winner in chemistry and ETH chemist Vladimir Prelog described as “one of the first problems of molecular theology” in his Nobel Prize lecture in 1975. But Ernst can imagine that in certain surface-catalyzed chemical reactions – such as those that could have taken place in the chemical “primordial soup” on the early Earth – a certain combination of electric and magnetic fields could have led to a steady accumulation of one form or another of the various biomolecules – and thus ultimately to the handedness of life. Reference: “Enantioselective Adsorption on Magnetic Surfaces” by Mohammad Reza Safari, Frank Matthes, Vasile Caciuc, Nicolae Atodiresei, Claus M. Schneider, Karl-Heinz Ernst and Daniel E. Bürgler, 28 December 2023, Advanced Materials. DOI: 10.1002/adma.202308666

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