Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Private label insole and pillow OEM China

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Taiwan ergonomic pillow OEM factory supplier

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Custom foam pillow OEM in Thailand

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Taiwan custom product OEM/ODM manufacturing factory

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Graphene insole manufacturer in Taiwan

Researchers have discovered a brain circuit in mice that inhibits eating when nauseous, pinpointing unique amygdala nerve cells that operate differently from those activated during satiety, highlighting the complex regulation of appetite. A neural pathway suppresses appetite when experiencing nausea. Feeling full, nauseous, or anxious can all contribute to a decrease in appetite. Postponing meals may be the body’s natural way to avoid additional harm and allow for recovery. Scientists at the Max Planck Institute for Biological Intelligence have discovered a specific brain pathway that stops mice from eating when they experience nausea. The decisive role is played by special nerve cells in the amygdala – a brain region involved when emotions run high. The cells are activated during nausea and elicit appetite-suppressing signals. The findings highlight the complex regulation of eating behavior, as the loss of appetite during nausea is controlled by different circuits than during satiety. An upcoming exam, a boat trip on the high seas, or the next germ at the daycare center all have one thing in common: they can really upset our stomach. Stress, motion sickness, or certain infections can make us feel sick. It seems logical that we don’t eat in these circumstances and wait for the situation to improve. As a result, nausea and decreased appetite usually go hand in hand. Or have you ever felt sick and really wanted to eat at the same time? Specialized nerve cells in the amygdala are activated during nausea and elicit appetite-suppressing signals. Credit: MPI for Biological Intelligence/ Julia Kuhl What seems logical is a healthy defense mechanism of our body – but it has to be activated first. Clearly, the brain plays a central role in this: it is the control center for the body’s energy balance and regulates eating behavior. So how does the brain prevent us from eating when we feel sick? Researchers in Rüdiger Klein’s department have gained new insights into this topic in mice. They focused on the amygdala, a brain region that regulates emotions, also those related to eating. It contains neurons that promote eating and those that inhibit appetite. For example, a known inhibitory cell type is activated when we are full, but how this works in the case of nausea is not well understood. Nausea activates nerve cells Wenyu Ding, first author of the new study, now discovered another cell group in the amygdala that has a negative influence on appetite. Unlike the previously known cell type, these cells are not activated by satiety, but when feeling nauseous. When the researchers artificially switched on the cells, even hungry mice stopped eating. Conversely, switching the cells off resulted in the mice eating, even when feeling sick. This Sketchnote summarizes the most important findings of the new paper. Credit: MPI for Biological Intelligence / Christina Bielmeier To better understand how this cell type exerts its appetite-suppressing function, the researchers analyzed the underlying circuit: where do the cells get their information from and to which cells and brain areas do they send their projections? The following picture emerged: When a mouse feels sick, this information reaches the brain and eventually the amygdala. There, the new cell type is activated and sends its inhibitory signals to distant brain regions, including the so-called parabrachial nucleus, a brain stem region that receives a lot of information about the internal state of the body. This stands in contrast to the circuit of the previously known cell type, which mainly interacts with neighboring cells within the amygdala. It becomes clear that the loss of appetite during satiety is not the same as the loss of appetite during nausea. In the brain, different cells and circuits are responsible for this – a complicated matter and perhaps a small consolation the next time we feel sick. Most importantly, the new study provides important insights into how the brain and the amygdala in particular regulate eating behavior. This is the prerequisite for a better understanding of the many diseases associated with dysregulated eating behavior in humans. Reference: “Nausea-induced suppression of feeding is mediated by central amygdala Dlk1-expressing neurons” by Wenyu Ding, Helena Weltzien, Christian Peters and Rüdiger Klein, 27 March 2024, Cell Reports. DOI: 10.1016/j.celrep.2024.113990

Researchers have utilized combat video game algorithms to analyze molecules’ movement within brain cells, a method previously used to track bullets. This innovative approach has shed light on brain cell activity, paving the way for advancements in neuroscience research. A video game algorithm repurposed by researchers now enables real-time tracking of molecular behavior in brain cells, unlocking new insights into their function and disorders. Researchers from The University of Queensland applied an algorithm from a video game to study the dynamics of molecules in living brain cells. Dr. Tristan Wallis and Professor Frederic Meunier from UQ’s Queensland Brain Institute came up with the idea while in lockdown during the COVID-19 pandemic. “Combat video games use a very fast algorithm to track the trajectory of bullets, to ensure the correct target is hit on the battlefield at the right time,” Dr Wallis said. “The technology has been optimized to be highly accurate, so the experience feels as realistic as possible. We thought a similar algorithm could be used to analyze tracked molecules moving within a brain cell.” Until now, technology has only been able to detect and analyze molecules in space, and not how they behave in space and time. “Scientists use super-resolution microscopy to look into live brain cells and record how tiny molecules within them cluster to perform specific functions,” Dr Wallis said. “Individual proteins bounce and move in a seemingly chaotic environment, but when you observe these molecules in space and time, you start to see order within the chaos. It was an exciting idea – and it worked.” Super-resolved imaging of Syntaxin 1A in the plasma membrane. Credit: The authors Adapting Gaming Tech for Molecular Movement Dr. Wallis used coding tools to build an algorithm that is now used by several labs to gather rich data about brain cell activity. “Rather than tracking bullets to the bad guys in video games, we applied the algorithm to observe molecules clustering together – which ones, when, where, for how long, and how often,” Dr Wallis said. “This gives us new information about how molecules perform critical functions within brain cells and how these functions can be disrupted during aging and disease.” Professor Meunier said the potential impact of the approach was exponential. “Our team is already using the technology to gather valuable evidence about proteins such as Syntaxin-1A, essential for communication within brain cells,” Professor Meunier said. “Other researchers are also applying it to different research questions. And we are collaborating with UQ mathematicians and statisticians to expand how we use this technology to accelerate scientific discoveries.” Professor Meunier said it was gratifying to see the effect of a simple idea. “We used our creativity to solve a research challenge by merging two unrelated high-tech worlds, video games, and super-resolution microscopy,” he said. “It has brought us to a new frontier in neuroscience.” Reference: “Super-resolved trajectory-derived nanoclustering analysis using spatiotemporal indexing” by Tristan P. Wallis, Anmin Jiang, Kyle Young, Huiyi Hou, Kye Kudo, Alex J. McCann, Nela Durisic, Merja Joensuu, Dietmar Oelz, Hien Nguyen, Rachel S. Gormal, and Frédéric A. Meunier, 8 June 2023, Nature Communications. DOI: 10.1038/s41467-023-38866-y

3D model and virtual reconstruction of the ear in a modern human (left) and the Amud 1 Neandertal (right). Credit: Mercedes Conde-Valverde Neanderthals had the auditory and vocal capabilities for human-like speech, with evidence pointing to complex communication systems and consonant use. Neanderthals — the closest ancestor to modern humans — possessed the ability to perceive and produce human speech, according to a new study published by an international multidisciplinary team of researchers including Binghamton University anthropology professor Rolf Quam and graduate student Alex Velez. “This is one of the most important studies I have been involved in during my career,” says Quam. “The results are solid and clearly show the Neanderthals had the capacity to perceive and produce human speech. This is one of the very few current, ongoing research lines relying on fossil evidence to study the evolution of language, a notoriously tricky subject in anthropology.” The evolution of language, and the linguistic capacities of Neanderthals in particular, is a long-standing question in human evolution. “For decades, one of the central questions in human evolutionary studies has been whether the human form of communication, spoken language, was also present in any other species of human ancestor, especially the Neanderthals,” says coauthor Juan Luis Arsuaga, Professor of Paleontology at the Universidad Complutense de Madrid and co-director of the excavations and research at the Atapuerca sites. The latest study has reconstructed how Neanderthals heard to draw some inferences about how they may have communicated. Reconstructed hearing patterns in modern humans, Neandertals and the Sima de los Huesos based on their ear anatomy. Compared with their ancestors from the Sima de los Huesos, the Neandertals more closely resemble modern humans in showing a heightened sensitivity between 3.5-5 kHz, a frequency range that contains acoustic information related to consonant production in human spoken language. Credit: Mercedes Conde-Valverde Neanderthal Hearing Matches Human Speech Frequencies The study relied on high-resolution CT scans to create virtual 3D models of the ear structures in Homo sapiens and Neanderthals as well as earlier fossils from the site of Atapuerca that represent ancestors of the Neanderthals. Data collected on the 3D models were entered into a software-based model, developed in the field of auditory bioengineering, to estimate the hearing abilities up to 5 kHz, which encompasses most of the frequency range of modern human speech sounds. Compared with the Atapuerca fossils, the Neanderthals showed slightly better hearing between 4-5 kHz, resembling modern humans more closely. In addition, the researchers were able to calculate the frequency range of maximum sensitivity, technically known as the occupied bandwidth, in each species. The occupied bandwidth is related to the communication system, such that a wider bandwidth allows for a larger number of easily distinguishable acoustic signals to be used in the oral communication of a species. This, in turn, improves the efficiency of communication, the ability to deliver a clear message in the shortest amount of time. The Neanderthals show a wider bandwidth compared with their ancestors from Atapuerca, more closely resembling modern humans in this feature. “This really is the key,” says Mercedes Conde-Valverde, professor at the Universidad de Alcalá in Spain and lead author of the study. “The presence of similar hearing abilities, particularly the bandwidth, demonstrates that the Neanderthals possessed a communication system that was as complex and efficient as modern human speech.” “One of the other interesting results from the study was the suggestion that Neandertal speech likely included an increased use of consonants,” said Quam. “Most previous studies of Neandertal speech capacities focused on their ability to produce the main vowels in English spoken language. However, we feel this emphasis is misplaced, since the use of consonants is a way to include more information in the vocal signal and it also separates human speech and language from the communication patterns in nearly all other primates. The fact that our study picked up on this is a really interesting aspect of the research and is a novel suggestion regarding the linguistic capacities in our fossil ancestors.” Speech Capacities Mirror Complex Behaviors Thus, Neanderthals had a similar capacity to us to produce the sounds of human speech, and their ear was “tuned” to perceive these frequencies. This change in the auditory capacities in Neanderthals, compared with their ancestors from Atapuerca, parallels archaeological evidence for increasingly complex behavioral patterns, including changes in stone tool technology, domestication of fire, and possible symbolic practices. Thus, the study provides strong evidence in favor of the coevolution of increasingly complex behaviors and increasing efficiency in vocal communication throughout the course of human evolution. The team behind the new study has been developing this research line for nearly two decades, and has ongoing collaborations to extend the analyses to additional fossil species. For the moment, however, the new results are exciting. “These results are particularly gratifying,” said Ignacio Martinez from Universidad de Alcalá in Spain. “We believe, after more than a century of research into this question, that we have provided a conclusive answer to the question of Neandertal speech capacities.” Reference: “Neandertals and modern humans had similar auditory and speech capacities” by Mercedes Conde-Valverde, Ignacio Martínez, Rolf M. Quam, Manuel Rosa, Alex D. Velez, Carlos Lorenzo, Pilar Jarabo, José María Bermúdez de Castro, Eudald Carbonell and Juan Luis Arsuaga, 1 March 2021, Nature Ecology and Evolution. DOI: 10.1038/s41559-021-01391-6

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