Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Graphene insole manufacturer in Indonesia

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Arch support insole OEM from Vietnam

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Private label insole and pillow OEM China

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.ODM service for ergonomic pillows Taiwan

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Graphene cushion OEM factory in Indonesia

Mother mouse takes care of its offspring. Watching a mother mouse gather her pups into the family’s nest trains other female mice without pups to perform the same parenting task, a new study shows. Furthermore, these observations lead to the production of oxytocin in the brains of virgin female mice, biochemically shaping their maternal behaviors even before they have pups of their own. Led by researchers at NYU Grossman School of Medicine, the new set of experiments involved round-the-clock filming of female mice interacting with their newborns as well as with virgin mice. Simultaneous electrical readings were made in several brain regions known to produce oxytocin or thought to be responding to the hormone. The research team built on its earlier studies of the so-called pleasure hormone showing that the release of oxytocin is essential not only for the onset of nursing but also for the initiating of other maternal behaviors. Publishing in the journal Nature online today (August 11, 2021), researchers describe what they called a never-before-seen behavior in which new mouse mothers would without prompting shepherd virgin female mice into the family’s nest along with their pups. Within 24 hours, the virgins began mimicking the maternal behavior of gathering the mom’s pups into the nest even if the mother was not there. Almost as quickly, virgin mice would also start to perform the pup-retrieving task without any direct contact with an experienced mouse mother and after having only “viewed” the mother through a clear plastic window. Mother mouse at top corrals virgin mouse (bottom) into nest in demonstration of “shepherding” behavior. Credit: NYU Langone The research team also measured brain electrical activity in virgin mice during shepherding and later when they became mothers on their own. They found that both the sight and sound of crying pups moving outside of their nest stimulated oxytocin production in a specific region of the brain, the hypothalamic paraventricular nucleus (PVN). By contrast, chemically blocking any of the visual, auditory, or oxytocin-producing PVN nerve pathways prevented virgin mice from learning to take care of pups. “Our study shows that in mice the best way to be a mom is to watch and learn from an experienced mom,” says study senior investigator Robert Froemke, PhD, a professor in the Skirball Institute of Biomolecular Medicine at NYU Langone Health. “Given the evidence, we propose that similar mechanisms operate in human mothers.” Froemke says the study findings in rodents add scientific evidence to the benefits observed from parenting classes in humans. He says the team next plans to examine if the same tutoring relationship exists among dad mice and virgin males. “This work redefines oxytocin’s role in brain function, broadening its impact to include formidable and complex social networking activities that force the brain to pay attention and adapt to its surroundings at the time, whether it’s reacting to the sound of a pup’s cries or feelings of happiness,” says Froemke, who also serves as a professor in the departments of Otolaryngology-Head and Neck Surgery, and Neuroscience and Physiology at NYU Langone. As part of the ongoing study, researchers analyzed nearly 5,000 hours (over six months) of video footage of several dozen mother mice interacting with their pups and with virgin mice. Reference: “Oxytocin neurons enable social transmission of maternal behaviour” by Ioana Carcea, Naomi López Caraballo, Bianca J. Marlin, Rumi Ooyama, Justin S. Riceberg, Joyce M. Mendoza Navarro, Maya Opendak, Veronica E. Diaz, Luisa Schuster, Maria I. Alvarado Torres, Harper Lethin, Daniel Ramos, Jessica Minder, Sebastian L. Mendoza, Chloe J. Bair-Marshall, Grace H. Samadjopoulos, Shizu Hidema, Annegret Falkner, Dayu Lin, Adam Mar, Youssef Z. Wadghiri, Katsuhiko Nishimori, Takefumi Kikusui, Kazutaka Mogi, Regina M. Sullivan and Robert C. Froemke, 11 August 2021, Nature. DOI: 10.1038/s41586-021-03814-7 Funding for the study was provided by NIH grants R01 HD088411, R01 DC12557, U19 NS107616, K99 MH106744, F32 MH112232, T32 MH019524, P30 CA016087, and P41 EB017183. Additional funding support was provided by Japan’s Strategic Program for Brain Sciences grant 16K15698; and scholarships from the McKnight Foundation, the Pew Charitable Trusts, and the Howard Hughes Medical Institute. Besides Froemke, other NYU Langone researchers involved in the study include lead study investigator Ioana Carcea, MD, PhD (now at Rutgers University in Newark, NJ); and study co-investigators Naomi Lopez Caraballo; Bianca Marlin, PhD; Rumi Ooyama; Joyce Mendoza Navarro; Maya Opendak, PhD; Veronica Diaz; Luisa Schuster; Maria Alvarado Torres; Harper Lethin; Daniel Ramos; Jessica Minder; Sebastian Mendoza; Chloe Bair-Marshall; Grace Samadjopoulos; Annegret Falkner, PhD; Dayu Lin, PhD; Adam Mar, PhD; Youssef Wadghiri, PhD; and Regina Sullivan, PhD. Other study co-investigators are Justin Riceberg, PhD, at the Icahn School of Medicine at Mount Sinai in New York City; Shizu Hidema, PhD; and Katsuhiko Nishimori, PhD, at Fukishima Medical University in Japan; and Takefumi Kikusui, PhD; and Kazutaka Mogi, PhD, at Azabu University in Kanagawa, Japan.

The frog sauna, which provides an artificially warmer hangout for frogs. These sun-heated brick “saunas” offer hope to some endangered amphibians being wiped out by a fungal infection that has already rendered at least 90 species extinct. Credit: Anthony Waddle A novel conservation method employing “frog saunas” helps green and golden bell frogs fight off the lethal chytrid fungus by raising their body temperatures. Successful trials in both controlled and natural environments suggest this technique could significantly aid in conserving this species. Impact of Chytrid Fungus on Amphibians As global diversity continues to decline due to a range of factors, amphibians have been particularly hard hit by infectious diseases. A pernicious fungal disease called chytridiomycosis, more commonly shortened to “chytrid,” has led to the extinction of 90 species of amphibians and has pushed another 500 species into decline. New research, though, offers hope in the form of “frog saunas.” Imagine not a traditional wood sauna beloved by Finns and Estonians, but rather a large, sun-heated brick structure with cubby holes where frogs can find refuge from colder weather. During winter, chytrid hits frogs harder, and the researchers speculated that if green and golden bell frogs were given an opportunity to get warmer in artificial saunas, they would take it. It turns out not only would they take the opportunity, raising their body temperature helped them clear the infection as well. Frog Saunas: A Novel Conservation Strategy Experiments were carried out in both lab and natural settings, where the frogs had both shaded and unshaded options and no inducement to access the saunas. But they took to the saunas like Finns in winter. The researchers also found that frogs that were initially infected and then fought off the infection after spending time in the sauna were significantly less likely to be reinfected. The paper, “Hotspot shelters stimulate frog resistance to chytridiomycosis,” was published in Nature. Of the 14 people listed as co-authors, 12 hail from Australia, where the research was conducted. The lone North American co-author is Erin Sauer, a postdoctoral fellow in biological sciences at the University of Arkansas. Development and Impact of Thermal Gradients In fact, the team’s work on frog saunas was inspired by Sauer’s previous research into how amphibian thermoregulatory behavior influences resistance to chytrid. For that study, done in 2018, Sauer designed thermal gradients she could keep frogs in for longer periods of time while measuring their thermal preferences. In practical terms, this meant putting a Plexiglas lid on sections of aluminum gutter that had a heating element on one end and cooling element on the other, providing a range of temperatures in between the two ends. She ultimately found that species that preferred warmer temperatures were able to clear their infections when they hung out on the warmer parts of the thermal gradients. “Anthony Waddle, the lead author on the Nature paper, got in touch with me because he wanted to build my thermal gradients in Australia and replicate my study with green and golden bell frogs,” Sauer explained. “So, I helped him design his setup and experiment in 2020-2021, and then helped with the data analysis for the lab study. “Very similar to my 2018 study, we found that the green and golden bell frogs preferred warm temperatures and were able to better resist their chytrid infections at those warm temperatures. Anthony and his colleagues in Australia then applied the findings from the lab experiment to build the frog saunas and run the mesocosm experiment.” Limitations and Applications of Amphibian Thermal Therapy While the findings suggest that the general public can play a role in saving green and golden bell frogs from extinction by building low-cost saunas in gardens or wetlands, Sauer cautions that this will not help all species of frogs. “My research has shown that while warm-adapted species have better disease outcomes at warm temperatures, cold-adapted species actually have worse outcomes at warm temperatures,” Sauer said. “My colleagues and I have termed this phenomenon the ‘thermal mismatch hypothesis’ and did a global study testing our hypothesis across systems a few years ago that was published in Science. So, unfortunately, the frog saunas won’t work for all species but work beautifully for the warm-preferring green and golden bell frogs.” For more on this research, see Frog ‘Saunas’ – Pandemic Protection for Endangered Frogs Facing a Deadly Global Fungus. Reference: “Hotspot shelters stimulate frog resistance to chytridiomycosis” by Anthony W. Waddle, Simon Clulow, Amy Aquilina, Erin L. Sauer, Shannon W. Kaiser, Claire Miller, Jennifer A. Flegg, Patricia T. Campbell, Harrison Gallagher, Ivana Dimovski, Yorick Lambreghts, Lee Berger, Lee F. Skerratt and Richard Shine, 26 June 2024, Nature. DOI: 10.1038/s41586-024-07582-y

“Origin of Life” artist’s concept. Researchers discovered viruses infecting Asgard archaea, ancestors of complex life, suggesting that viruses may have played a role in the evolution of eukaryotes. The first discovery of viruses infecting a group of microbes that may include the ancestors of all complex life has been found, scientists at The University of Texas at Austin (UT Austin) report in Nature Microbiology. The incredible discovery offers tantalizing clues about the origins of complex life and suggests new directions for investigating the hypothesis that viruses were essential to the evolution of humans and other complex life forms. There is a well-supported hypothesis that all complex life forms such as humans, starfish, and trees — which feature cells with a nucleus and are called eukaryotes — originated when archaea and bacteria merged to form a hybrid organism. Recent research suggests the first eukaryotes are direct descendants of so-called Asgard archaea. The latest research, by Ian Rambo (a former doctoral student at UT Austin) and other members of Brett Baker’s lab, sheds light on how viruses, too, may have played a role in this billions-year-old history. Comparison of all known virus genomes. Those viruses with similar genomes are grouped together including those that infect bacteria (on the left), eukaryotes (on the right and bottom center). The viruses that infect Asgard archaea are unique from those that have been described before. Credit: University of Texas at Austin The Role of Viruses in Complex Life Evolution “This study is opening a door to better resolving the origin of eukaryotes and understanding the role of viruses in the ecology and evolution of Asgard archaea,” Rambo said. “There is a hypothesis that viruses may have contributed to the emergence of complex cellular life.” Researchers from UT Austin used the Alvin submersible to collect sediment samples and microbes from 2000m (6600 feet) deep in the Gulf of California. Credit: Brett Baker Rambo is referring to a hotly debated hypothesis called viral eukaryogenesis. It suggests that, in addition to bacteria and archaea, viruses might have contributed some genetic component to the development of eukaryotes. While this latest discovery does not settle that debate, it does offer some interesting clues. The newly discovered viruses that infect currently living Asgard archaea do have some features similar to viruses that infect eukaryotes, including the ability to copy their own DNA and hijack the protein modification systems of their hosts. The fact that these recovered Asgard viruses display characteristics of both viruses that infect eukaryotes and prokaryotes, which have cells without a nucleus, makes them unique since they are not exactly like those that infect other archaea or complex life forms. A New Window into Ancient Microbial Life “The most exciting thing is they are completely new types of viruses that are different from those that we’ve seen before in archaea and eukaryotes, infecting our microbial relatives,” said Baker, associate professor of marine science and integrative biology and corresponding author of the study. The Asgard archaea, which probably evolved more than 2 billion years ago and whose descendants are still living, have been discovered in deep-sea sediments and hot springs around the world, but so far only one strain has been successfully grown in the lab. To identify them, scientists collect their genetic material from the environment and then piece together their genomes. In this latest study, the researchers scanned the Asgard genomes for repeating DNA regions known as CRISPR arrays, which contain small pieces of viral DNA that can be precisely matched to viruses that previously infected these microbes. These genetic “fingerprints” allowed them to identify these stealthy viral invaders that infect organisms with key roles in the complex origin story of eukaryotes. Researchers from UT Austin used the Alvin submersible to collect sediment samples and microbes from 2000m (6600 feet) deep in the Gulf of California. Credit: Brett Baker “We are now starting to understand the implication and role that viruses could have had in the eukaryogenesis puzzle,” said Valerie De Anda, a research associate at UT Austin and co-author of the study. Reference: “Genomes of six viruses that infect Asgard archaea from deep-sea sediments” by Ian M. Rambo, Marguerite V. Langwig, Pedro Leão, Valerie De Anda and Brett J. Baker, 27 June 2022, Nature Microbiology. DOI: 10.1038/s41564-022-01150-8 The other co-authors of the study are Pedro Leão, a postdoctoral research fellow at UT Austin, and Marguerite Langwig, formerly a master’s student at UT Austin and currently a doctoral candidate at the University of Wisconsin-Madison. This work was supported by the Moore and Simons Foundations.

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