Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Thailand eco-friendly graphene material processing

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.ESG-compliant OEM manufacturer in China

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Vietnam graphene product OEM service

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Innovative insole ODM solutions factory in Taiwan

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Custom foam pillow OEM in Vietnam

Cinnabar larvae feeding on ragwort. Credit: Callum McLellan Young birds that eat insects with conspicuous warning coloration to advertise their toxicity to would-be predators quickly learn to avoid other prey that carry the same markings. Developing on this understanding, a University of Bristol team has shown for the very first time that birds don’t just learn the colors of dangerous prey, they can also learn the appearance of the plants such insects live on. To do this, the scientists exposed artificial cinnabar caterpillars, characterized by bright yellow and black stripes, and non-signaling fake caterpillar targets to wild avian predation by presenting them on ragwort and a non-toxic plant — bramble, which is not a natural host of the cinnabar. Both target types survived better on ragwort compared to bramble when experienced predators were abundant in the population. An adult cinnabar moth on a ragwort stem. Credit: Callum McLellan They were also interested in whether birds use the bright yellow flowers of ragwort as a cue for avoidance. They tested this by removing spikes of flowers from the ragwort and pinning them onto bramble, then recording target survival on either plant. In this second experiment, only the non-signaling targets survived better on plants with ragwort flowers, compared to the same plant type without the flowers. The survival of the cinnabar-like target was equal across all plant treatments Lead author Callum McLellan, a graduate student at the School of Biological Sciences, said “Cinnabar caterpillars have this really recognizable, stripey yellow and black appearance. They also only live and feed on ragwort, which itself has distinctive yellow flowers. We have shown that birds learn that the ragwort flowers are a cue for danger, so can avoid going anywhere near toxic prey. It’s more efficient to avoid the whole plant than make decisions about individual caterpillars.” Ragwort. Credit: Callum McLellan Co-author Prof Nick Scott-Samuel of the School of Psychological Science, said: “Our findings suggest that insect herbivores that specialize on easily recognizable host plants gain enhanced protection from predation, independent of their warning signal alone.” Prof Innes Cuthill, who conceived the study, added “Interestingly, any camouflaged caterpillars living on the same plant also benefit from birds’ learned wariness of ragwort, despite being perfectly good to eat. “Our results provide the opening to a brand-new discussion on how toxicity initially evolved in insect prey, and the conditions under which warning coloration is, or is not, favored.” Reference: “Birds learn to avoid aposematic prey by using the appearance of host plants” by Callum F. McLellan, Nicholas E. Scott-Samuel and Innes C. Cuthill, 7 October 2021, Current Biology. DOI: 10.1016/j.cub.2021.09.048

Scientists have made a major advance toward understanding the molecular mechanisms that are involved in the creation of spatial maps in the brain. The Fos gene plays a key role in forming stable brain maps for navigation, linking molecular processes to memory and behavior. Research in mice illuminates the molecular mechanisms that underlie spatial mapping in the brain Researchers found that a gene called Fos plays a key role in helping the brain use specialized navigation cells to form and maintain spatial maps The findings bring us one step closer to a complete understanding of how the brain creates memories of spatial maps for navigation Anytime we venture into a new location, our brain’s built-in GPS immediately activates and begins to form a spatial map of our surroundings. Over a period of days and even weeks, this map may be solidified as a memory that we can recall to help us navigate more easily whenever we return to that particular place. Just how the brain forms these spatial maps is astoundingly complex. It is a process that involves an intricate molecular interplay across genes, proteins, and neural circuits to shape behavior. Perhaps unsurprisingly given this immense complexity, the precise steps of this multiplayer interaction have eluded neurobiologists. Now, scientists have made a major advance toward understanding the molecular mechanisms that are involved in the creation of spatial maps in the brain. The researchers worked through a multilab collaboration within the Blavatnik Institute at Harvard Medical School. The new study, conducted in mice and published today (August 24, 2022) in the journal Nature, establishes that a gene called Fos is a key player in spatial mapping, helping the brain use specialized navigation cells to form and maintain stable representations of the environment. “This research connects across the different levels of understanding to make a pretty direct link between molecules and the function of circuits for behavior and memory,” said Christopher Harvey, associate professor of neurobiology at HMS and senior author of the study. “Here we can understand what’s actually underlying the formation and stability of spatial maps.” If the findings translate into humans, they will provide crucial new information about how our brains construct spatial maps. Eventually, this knowledge could help researchers better understand what happens when this process breaks down, as it often does as a result of brain injury or neurodegeneration.  The Role of the Hippocampus in Navigation and Memory Lying deep in the brain’s temporal lobe, the hippocampus plays an essential role in learning, memory, and navigation for many species, including mice and humans. Scientists have long known that for navigation, the hippocampus contains specialized neurons called place cells that selectively become active when an animal is at different locations in space. By turning on and off as an animal moves through its environment, place cells essentially construct a map of the surrounding area that can be incorporated into a memory. “My lab has studied spatial navigation for years, including how place cells form a map of the environment and form spatial memories,” Harvey said, and yet “the molecular mechanisms that underlie those processes have been difficult to study in the behaving animal.” To study the molecular cascade involved in this mapping process, Harvey and first author Noah Pettit teamed up with co-senior author Michael Greenberg and author Lynn Yap. Pettit is a research fellow in neurobiology in the Harvey lab, Greenberg is the Nathan Marsh Pusey Professor of Neurobiology at HMS, and Yap is a graduate of the Harvard PhD Program in Neuroscience who did her doctoral work in the Greenberg lab. Fos Expression and Its Link to Place Cells Greenberg’s lab studies the Fos gene, which codes for a transcription factor protein that regulates the expression of other genes. In previous research, Greenberg and his colleagues showed that Fos is expressed minutes after a neuron is activated, making it a useful marker for neural activity in the brain. They also demonstrated that Fos acts as a mediator for different types of neural plasticity, including navigation and memory formation. However, the relationship between Fos and place cells in the hippocampus was not known. The team wondered whether Fos could be involved in how mice form spatial maps as they navigate their environment. To find out, the investigators used a technique developed in Harvey’s lab that places mice in a virtual reality maze: A mouse runs on a ball as it looks at a large, surround screen that displays a spatial navigation task such as solving a maze to find a reward. As the mouse jogs on the ball and performs the task, researchers record neural activity and changes in Fos expression in the hippocampus. In what Greenberg called “a technical tour de force,” Pettit led a series of complicated experiments to unravel the connection between Fos and place cells. The researchers found that in the hours after a mouse performed a navigation task, neurons with high Fos expression were more likely to form accurate place fields — clusters of place cells that signal spatial position — than those with low Fos expression. Moreover, neurons with high Fos expression had place fields that were more reliable over time in indicating spatial position as the mouse repeated the task on subsequent days. “This tells us that on a moment-to-moment basis as the mouse is navigating, the neurons that induce Fos have very robust information about the mouse’s spatial position, which is the key variable needed to solve and remember the task,” Pettit explained. When the team knocked out Fos in a subset of neurons within the hippocampus, they observed that those cells had less accurate spatial maps of the environment than nearby neurons with normal Fos expression. Also, the maps in cells lacking Fos were less stable across days, and thus, were less reliable as memories of the environment. Fos’s Role in Maintaining Stable Spatial Maps “Fos seems to be important for maintaining the stability and accuracy of place cells, and representing a spatial map in the brain over time,” Greenberg said. “There have been a lot of studies on Fos and there have been a lot of studies on place cells, but this is one of the first papers that directly connects the two,” Harvey added, “It opens a lot of exciting new directions for investigating these mechanisms.” For instance, Greenberg would like to delve into the specific molecules and cells that are involved as Fos helps the brain form and maintain stable spatial maps over time. He also wants to understand the different roles Fos may play as spatial map memories are transferred from the hippocampus to other brain regions. In a similar vein, Harvey is interested in whether Fos is part of the process by which spatial map memories are solidified during sleep. Although the study was done in mice, the scientists noted that much of the system is conserved across species, including humans. If the findings can be confirmed in humans, they could help scientists understand how our brains form spatial maps and what happens when we lose this ability due to injury or disease.  Beyond the science, the researchers emphasized that the research represents an unusual partnership between a laboratory that studies cellular and molecular mechanisms and one that focuses on animal behavior and neural circuits. “Our two laboratories are about as far from each other in terms of what we do as any in the department, but we’ve come together to study how molecules interact with neural circuits that control learning, memory, and behavior,” Greenberg said. “This was a natural and exciting collaboration to learn that Fos plays a role in spatial memories and spatial navigation,” Harvey agreed. “It’s hard to be an expert in all these different levels of neurobiology, but by working together, the two labs have been able to bridge the gap.” Reference: “Fos ensembles encode and shape stable spatial maps in the hippocampus” by Noah L. Pettit, Ee-Lynn Yap, Michael E. Greenberg and Christopher D. Harvey, 24 August 2022, Nature. DOI: 10.1038/s41586-022-05113-1 Funding was provided by the National Institutes of Health (grants DP1 MH125776, R01 NS089521, R01 NS028829), Stuart H.Q. & Victoria Quan Fellowship, HMS Department of Neurobiology graduate fellowship, and Harvard Aramont Fellowship Fund for Emerging Science Research. The Greenberg lab is supported by the Allen Discovery Centers.

Industrial agriculture has reshaped plant evolution to prioritize high yields, often overlooking environmental adaptability and resilience. University of Vermont researchers emphasize the importance of smallholder farmers’ diverse, locally adapted crops (landraces) for future food security in a climate-changing world, advocating for policies that value and integrate these traditional seeds and farming insights for sustainable agriculture. In a shifting climate, smallholder farmers are essential for global food security: adapting seeds is crucial, according to UVM evolutionary biologist Yolanda Chen. Since World War II, humans have profoundly transformed the evolution of agricultural plants, reshaping our seed systems through industrial farming methods to meet the demands of a growing population. However, according to UVM researchers, in the face of a changing climate in the coming decades, the seeds that will sustain the world are in the care of smallholder farmers. In a new discussion in Plants, People, Planet, Chen and coauthors examine how the emergence of professional crop breeders has “disrupted evolutionary processes” to “reshape the entire food system.” The mass production of high-yielding seeds in limited varieties has created a chasmic divide between a “formal seed system,” which now sells most seeds worldwide, and the “informal seed system”, which consists of farmers who select their own seeds to develop diverse, locally adapted crop varieties, known as landraces. In selecting these landraces, smallholder farmers provide evosystem services—the benefits we gain from biodiversity, developed through evolutionary processes, Chen, a Fellow at the Gund Institute for Environment, explains. These services include crops’ adaptation to stresses including drought, salinity, and pests, which, she adds, are expected to increase as the climate warms, noting such services are crucial for the future of sustainability. “Formal seed system crop breeders have selected varieties with a singular focus on achieving high yields,” Chen says. “The assumption is that breeding is a science of unlocking a crop’s yield potential—that modernity will feed the world.” This has been achieved using fertilizers, irrigation, and pesticides to recreate essentially the same fertile environment regardless of location. Crop breeders have selected modern seed varieties to grow in these ideal conditions, Chen says. Modern Seeds Are Feeling the Heat But outside those conditions, crop plants have evolved alongside microbial and animal species to tolerate a wide range of environments. For example, many plants produce compounds that attract local insects to prey on the plant’s parasites. In other words, says Chen, they’ve evolved a trait to “call in bodyguards.” But plants from mass-produced seed haven’t retained this trait, which they don’t need with “constant support from pesticides,” Chen says. Having lost this ancient connection to their environment, plants don’t issue that call for help: “formal seed system crops have been selected to be mute.” Of course, humans guiding crops’ evolution is nothing new, Chen says. Similar to interactions between plants and ecosystems, selective crop breeding by humans shapes crops for the places and climates where they’re planted. Conversely, depending on crops with high yields but no connection to their environment is a tradeoff. One-size-fits-all agriculture is quickly becoming an untenable prospect under the extreme heat or drought that many agricultural areas anticipate. So what happens in extreme climates, when we can no longer create the perfect environment for formal seed system crops? The Need for Diverse Seeds The solution, Chen and co-authors propose, lies in pockets, sheds and barns across the world: that vast diversity of landrace seeds, tucked away by people growing crops in every possible ecosystem. Bred to yield in the mountains, deltas and deserts where farmers plant them, landrace seeds have the best chance of carrying the hardy traits needed to survive in whatever conditions climate change has in store. “Landraces hold traits that will help the more commercial varieties adapt to local conditions,” Chen says: those evosystem services, bred into landrace seeds as fully as their vibrant flavors and colors. But the issue isn’t just genetics, and Chen, an insect evolutionary ecologist, works with an interdisciplinary team including sociologists and plant geneticists. In modern agriculture, Chen sees “neocolonial ideas around who gets to decide what is important.” The farmers who’ve developed landraces are often smallholders in historically colonized places, their work unvalued in industrial agriculture or academic research. The seed diversity smallholder farmers grow has been considered “a global public good,” Chen says. “But what’s in it for the smallholder farmer who’s incurred the costs of growing these landrace seeds?” As climate conditions make modern agricultural practices unsustainable, the solution isn’t for industrialized countries to ask seed-saving smallholders in developing countries, “‘Our crops are failing; can we have your seeds?’” Chen says. “We need to find mechanisms for valuing and sharing seed diversity, to manage the evolution of our food crops,” she says. “And we don’t need to ask smallholder farmers around the world to carry the future of food security.” Instead, Chen and her colleagues are creating a policy brief to share their knowledge with policymakers. Their goal is to establish practices that promote benefit-sharing to properly support smallholder farmers for the seed diversity they’ve created. A concurrent goal is finding ways to incorporate these farmers’ knowledge so this seed diversity can be utilized for the next generation of large-scale crops. “It’s a paradigm shift from this ‘yield, yield, yield’ mentality,” Chen says. “We must center evolution and biodiversity in our agricultural processes. That’s how you achieve sustainability.” Reference: “Human management of ongoing evolutionary processes in agroecosystems” by Alicia Mastretta-Yanes, Daniel Tobin, Mauricio R. Bellon, Eric von Wettberg, Angélica Cibrián-Jaramillo, Ana Wegier, Ana Sofía Monroy-Sais, Nancy Gálvez-Reyes, Jorge Ruiz-Arocho and Yolanda H. Chen, 11 June 2024, Plants, People, Planet. DOI: 10.1002/ppp3.10521

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