Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw

China orthopedic insole OEM manufacturer

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Soft-touch pillow OEM service in China

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.China custom product OEM/ODM services

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Thailand sustainable material ODM solutions

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.One-stop OEM/ODM solution provider Vietnam

Due to a regular surface structure on the mussel “Adamussium colbecki” ice adheres to it only very weakly and can be easily washed away by currents. Credit: MPI-P Special shell protects Antarctic scallop from ice build-up. Airplane wings that don’t ice up or solar cells that generate electricity even in winter – ice-free surfaces are important for many applications. A team of scientists led by Konrad Meister, professor at the University of Alaska Southeast and group leader at the Max Planck Institute for Polymer Research, has now studied an Antarctic scallop species that opposes the icing process with the help of its shell surface. Due to their special structure, thin layers of ice adhere poorly and are easily washed away by the flow. The discovery could help in the development of ice-free bionic surfaces in the long term. Antarctic waters have conditions in which objects and living creatures can freeze even under water. This is a major problem for marine travel in polar regions. So-called supercooled water has a temperature just below the freezing point. Due to the high salt content, water in Antarctica has a freezing point of about -1.9 °C (28.6 °F), but is about 0.05 °C colder (0.09 °F). The smallest disturbances such as grains of sand or surfaces can cause this supercooled water to freeze – with sometimes fatal consequences for creatures that cannot survive frozen. Special Surface Structure Prevents Icing The Antarctic scallop “Adamussium colbecki” resists this, as chemist Konrad Meister knows. Meister is a professor at the University of Alaska and heads a research group in Mischa Bonn’s department at the Max Planck Institute for Polymer Research (MPI-P) in Mainz. During an expedition in Antarctica, divers drew his attention to the scallop with the efficient ice protection mechanism. “Our divers reported that they had never observed large-scale ice on the surface of this native scallop species,” Meister says. The international research team, consisting of members of several MPI-P research groups as well as the University of Oregon, suspects that the scallop species developed a special surface structure during evolution that protects it from icing. While scallops in warmer regions have disordered or smooth shell surfaces, the Antarctic species has a microscopic, very regular structure. Microscopic Ridges and Ice Removal Efficiency The microscope reveals small ridges that run in a radiating pattern on their shell. These ridges ensure that water freezes preferentially there. If the freezing process continues, a continuous layer of ice forms, resting only on the ridges. Due to the low adhesion between ice and shell, the smallest underwater flow can therefore wash off the ice again and the scallop does not freeze. In addition to microscope studies, the research team also conducted icing experiments with the Antarctic and with a scallop from warmer regions. It was found that far less force is needed to remove the ice layer on the Antarctic scallop than for the other species. “It is exciting how evolution has obviously given this scallop an advantage,” says Konrad Meister. “New technological applications based on the principle of bionics are conceivable from the knowledge of the ice-free shell. For example, non-icing surfaces could be highly interesting for polar shipping.” The researchers have now published their research in the scientific journal Communications Biology, a journal from the Nature portfolio. Reference: “Cryofouling avoidance in the Antarctic scallop Adamussium colbecki” by William S. Y. Wong, Lukas Hauer, Paul A. Cziko and Konrad Meister, 21 January 2022, Communications Biology. DOI: 10.1038/s42003-022-03023-6

The Icahn School of Medicine at Mount Sinai unveiled mEnrich-seq, a groundbreaking method for microbiome research, enabling more precise and efficient study of specific bacteria in the human body. This innovative approach promises to advance research in areas like antibiotic resistance and offers broad applicability in both research and clinical settings. Credit: SciTechDaily.com Genomic ‘Tweezer’ Ushers In a New Era of Precision in Microbiome Research Innovative method holds the potential to reshape our understanding of bacteria’s role in health and disease. In a landmark study published today (January 4) in the journal Nature Methods, researchers at the Icahn School of Medicine at Mount Sinai have unveiled mEnrich-seq—an innovative method designed to substantially enhance the specificity and efficiency of research into microbiomes, the complex communities of microorganisms that inhabit the human body. Unlocking the Microbial World with mEnrich-seq Microbiomes play a crucial role in human health. An imbalance or a decrease in the variety of microbes in our bodies can lead to an increased risk of several diseases. However, in many microbiome applications, the focus is on studying specific types of bacteria in a sample, rather than looking at each type present. For example, when studying infectious diseases, researchers might only be interested in a few harmful gut bacteria, but they are mixed in with many other bacteria. “Imagine you’re a scientist who needs to study one particular type of bacteria in a complex environment. It’s like trying to find a needle in a large haystack,” said Gang Fang, PhD, Professor of Genetics and Genomic Sciences and the study’s senior author. “mEnrich-seq essentially gives researchers a ‘smart tweezer’ to pick up the needle they’re interested in.” mEnrich-seq can be used to examine various bacteria of interest from the same microbiome sample. Credit: Icahn School of Medicine at Mount Sinai Once pulled out by the “smart tweezer,” researchers can assemble the genome(s) of the targeted bacteria, facilitating the study of diverse biomedical questions about them. This new strategy addresses a critical technology gap, as previously researchers would need to isolate specific bacterial strains from a given sample using culture media that selectively grow the specific bacterium—a time-consuming process that works for some bacteria, but not others. mEnrich-seq, in contrast, can directly recover the genome(s) of bacteria of interest from the microbiome sample without culturing. mEnrich-seq effectively distinguishes bacteria of interest from the vast background by exploiting the “secret codes” written on bacterial DNA that bacteria use naturally to differentiate among each other as part of their native immune systems. Transforming Research and Health Care The advent of mEnrich-seq opens new horizons in various fields: Cost-Effectiveness: It offers a more economical approach to microbiome research, particularly beneficial in large-scale studies where resources may be limited. Broad Applicability: The method can focus on a wide range of bacteria, making it a versatile tool for both research and clinical applications. Medical Breakthroughs: By enabling more targeted research, mEnrich-seq could accelerate the development of new diagnostic tools and treatments. “One of the most exciting aspects of mEnrich-seq is its potential to uncover previously missed details, like antibiotic resistance genes that traditional sequencing methods couldn’t detect due to a lack of sensitivity,” Dr. Fang added. “This could be a significant step forward in combating the global issue of antibiotic resistance.” Indeed, as demonstrated as one of three applications in this study, the authors used mEnrich-seq to directly reconstruct pathogenic E. coli genomes from urine samples from patients with urinary tract infections, which allowed the comprehensive analysis of the antibiotic resistance genes in each genome. In another application, the authors used mEnrich-seq to selectively construct the genomes of Akkermansia muciniphila, a bacterium that has been shown to have benefits in obesity and diabetes, among several other diseases, as well as a response to cancer immunotherapy. This bacterium is hard to culture, so mEnrich-seq can be a useful tool to reconstruct its genome in a culture-independent, sensitive, and cost-effective way, which may facilitate larger-scale association studies with different human diseases. The Future of mEnrich-seq Looking ahead, the team has ambitious plans for mEnrich-seq. They aim to refine the method to improve its efficiency further and to expand its range of applications. Collaborations with clinicians and healthcare professionals are also in the pipeline to validate the method’s utility in real-world settings. “We envision mEnrich-seq as a sensitive and versatile tool in the future of microbiome studies and clinical applications,” said Dr. Fang. Reference: “mEnrich-seq: methylation-guided enrichment sequencing of bacterial taxa of interest from microbiome” by Lei Cao, Yimeng Kong, Yu Fan, Mi Ni, Alan Tourancheau, Magdalena Ksiezarek, Edward A. Mead, Tonny Koo, Melissa Gitman, Xue-Song Zhang and Gang Fang, 4 January 2023, Nature Methods. DOI: 10.1038/s41592-023-02125-1 This work was supported by a grant number R35 GM139655 from the National Institutes of Health.

After a 1988 algal bloom decimated snails in Sweden’s Koster archipelago, researchers reintroduced Crab snails and observed fast evolutionary adaptations. (Swedish L. saxatilis marine snails.) Credit: Daria Shipilina The Koster archipelago’s snail populations, affected by a toxic algae bloom, became the focus of a decades-long study revealing how rapid evolutionary changes can occur when driven by genetic diversity and environmental pressures. In 1988, the Koster archipelago, a cluster of islands off Sweden’s west coast near Norway, was struck by a particularly dense bloom of toxic algae, decimating the marine snail populations. One might wonder why the fate of snails on a tiny, three-square-meter rock in the open sea would matter. Yet, this event would create a unique opportunity to predict and witness evolution unfolding before our eyes. Previously, the islands and their small intertidal skerries—rocky islets—harbored dense and diverse populations of the marine snail species Littorina saxatilis. Although the snail populations on the larger islands—some of which were reduced to less than 1%—rebounded within two to four years, several skerries struggled to recover from the devastation. Crab-ecotype snails (1992) evolved to strikingly resemble the lost Wave-ecotype snails on a skerry. Credit: ISTA, images by Kerstin Johannesson A Groundbreaking Experiment Begins Marine ecologist Kerstin Johannesson from the University of Gothenburg, Sweden, saw a unique opportunity. In 1992, she re-introduced L. saxatilis snails to their lost skerry habitat—starting an experiment that would have far-reaching implications more than 30 years later. It allowed an international collaboration led by researchers from the Institute of Science and Technology Austria (ISTA), Nord University, Norway, the University of Gothenburg, Sweden, and The University of Sheffield, UK, to predict and witness evolution in the making. L. saxatilis is a common species of marine snails found throughout the North Atlantic shores, where different populations evolved traits adapted to their environments. These traits include size, shell shape, shell color, and behavior. The differences among these traits are particularly striking between the so-called Crab- and Wave-ecotype. These snails have evolved repeatedly in different locations, either in environments exposed to crab predation or on wave-exposed rocks away from crabs. Wave snails are typically small, and have a thin shell with specific colors and patterns, a large and rounded aperture, and bold behavior. Crab snails, on the other hand, are strikingly larger, have thicker shells without patterns, and a smaller and more elongated aperture. Crab snails also behave more warily in their predator-dominated environment. The Crab ecotype (left) is larger and wary of predators. The Wave ecotype (right) is smaller and has bold behavior. Credit: David Carmelet The Swedish Koster archipelago is home to these two different L. saxatilis snail types, often neighboring one another on the same island or only separated by a few hundred meters across the sea. Before the toxic algal bloom of 1988, Wave snails inhabited the skerries, while nearby shores were home to both Crab and Wave snails. This close spatial proximity would prove crucial. Crab-ecotype L. saxatilis snails were brought here in 1992 after toxic algae wiped out the original Wave-ecotype population. Credit: Kerstin Johannesson Rediscovering Evolutionary Traits Seeing that the Wave snail population of the skerries was entirely wiped out due to the toxic algae, Johannesson decided in 1992 to reintroduce snails to one of these skerries, but of the Crab-ecotype. With one to two generations each year, she rightfully expected the Crab snails to adapt to their new environment before scientists’ eyes. “Our colleagues saw evidence of the snails’ adaptation already within the first decade of the experiment,” says Diego Garcia Castillo, a graduate student in the Barton Group at ISTA and one of the authors leading the study. “Over the experiment’s 30 years, we were able to predict robustly what the snails will look like and which genetic regions will be implicated. The transformation was both rapid and dramatic,” he adds. The donor shore of the transplanted snail population (foreground) and the experimental skerry (little dot in the sea to the right). Credit: Kerstin Johannesson However, the snails did not evolve these traits entirely from scratch. Co-corresponding author Anja Marie Westram, a former postdoc at ISTA and currently a researcher at Nord University, explains, “Some of the genetic diversity was already available in the starting Crab population but at low prevalence. This is because the species had experienced similar conditions in the recent past. The snails’ access to a large gene pool drove this rapid evolution.” Johannesson is a marine ecologist at the University of Gothenburg, Sweden. Credit: Bo Johannesson Genetic Diversity and Evolutionary Change The team examined three aspects over the years of the experiment: the snails’ phenotype, individual gene variabilities, and larger genetic changes affecting entire regions of the chromosomes called “chromosomal inversions.” In the first few generations, the researchers witnessed an interesting phenomenon called “phenotypic plasticity”: Very soon after their transplantation, the snails modified their shape to adjust to their new environment. But the population also quickly started to change genetically. The researchers could predict the extent and direction of the genetic changes, especially for the chromosomal inversions. They showed that the snails’ rapid and dramatic transformation was possibly due to two complementary processes: A fast selection of traits already present at a low frequency in the transplanted Crab snail population and gene flow from neighboring Wave snails that could have simply rafted over 160 meters to reach the skerry. First author Diego Garcia Castillo, graduate student at ISTA, visiting the experimental skerry. Credit: Pierre Barry Evolution in the Face of Environmental Pressures In theory, scientists know that a species with high enough genetic variation can adapt more rapidly to change. However, few studies aimed to experiment with evolution over time in the wild. “This work allows us to have a closer look at repeated evolution and predict how a population could develop traits that have evolved separately in the past under similar conditions,” says Garcia Castillo. The team now wants to learn how species can adapt to modern environmental challenges such as pollution and climate change. “Not all species have access to large gene pools and evolving new traits from scratch is tediously slow. Adaptation is very complex and our planet is also facing complex changes with episodes of weather extremes, rapidly advancing climate change, pollution, and new parasites,” says Westram. She hopes this work will drive further research on maintaining species with large and diverse genetic makeups. “Perhaps this research helps convince people to protect a range of natural habitats so that species do not lose their genetic variation,” Westram concludes. Now, the snails Johannesson brought to the skerry in 1992 have reached a thriving population of around 1,000 individuals. Reference: “Predicting rapid adaptation in time from adaptation in space: A 30-year field experiment in marine snails” by Diego Garcia Castillo, Nick Barton, Rui Faria, Jenny Larsson, Sean Stankowski, Roger Butlin, Kerstin Johannesson and Anja M. Westram, 11 October 2024, Science Advances. DOI: 10.1126/sciadv.adp2102

DVDV1551RTWW78V