Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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High-performance graphene insole OEM Vietnam

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Taiwan graphene product OEM service

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Taiwan neck support pillow OEM

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Soft-touch pillow OEM service in China

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Pillow OEM for wellness brands Vietnam

Aspergillus flavus is uniquely adapted to survive in bee colonies. Credit: Ling-Hsiu Liao Studies reveal Aspergillus flavus’s unique adaptations to thrive in the harsh conditions of bee hives, suggesting a potential symbiotic relationship with bees. Previous research efforts to catalog the fungal diversity in honey bee colonies have consistently identified Aspergillus flavus as a common presence in hives. The past attempts of honey bee researchers to inventory the fungal diversity in honey bee colonies revealed that Aspergillus flavus is frequently found in hives. In a new study, scientists have discovered that this fungus is uniquely adapted to survive in bee colonies. The western honey bee, Apis mellifera, stores large quantities of food in the form of bee bread, which serves as the primary nourishment for the colony. This nutrient-rich food source attracts various microorganisms, despite its acidic nature and low moisture content. Additionally, bee bread is coated with propolis, an antimicrobial substance, creating a challenging environment for microbial survival. Microbial Life in Bee Colonies Despite the inhospitable nature of bee bread, the microbiome in hives consists of several bacterial and fungal species that are important to honey bee food preparation, storage, and digestion. “Most of the research on bee bread has been focused on bacteria and it was assumed that fungi didn’t play a big role because the bacteria made it too inhospitable to them,” said Daniel Bush, a graduate student in the Berenbaum (IGOH/GEGC/GNDP) lab. “After talking to mycologists, I suspected that wasn’t the case and I set out to demonstrate that fungi were capable of living successfully in bee bread.” Research on Fungal Strains In the study, the researchers used three strains of A. flavus: one that is not found in bee hives, a strain that was isolated from hives in central Illinois, and a pathogenic strain from a honey bee colony that had a stonebrood infection. They first tested whether the strains showed any differences in their responses to pH and temperature. The latter was looked at because hives are characterized by higher year-round temperatures compared to the outside environments, which is a challenge for many microbes. Although the strains were all able to grow across different temperature ranges, they had visible growth differences under different pH conditions. The strain that was isolated from the hives was able to withstand low pH, while the other two could not. Adaptation and Genetic Analysis The strains were also tested under different matric potential, which measures how much moisture is available, and response to propolis. “We saw that the strain from the hive was capable of dealing with extreme levels of environmental pressure from colony-specific sources,” Bush said. “It was interesting that it could deal with propolis, which is believed to have fungicidal properties.” To better understand how the hive-associated fungal species were able to adapt, the researchers also sequenced the A. flavus strain and found that it had several genetic mutations that allowed it to tolerate the harsh conditions of the bee bread environment. Ongoing Research and Future Directions “We believe that these are signs that there is a level of adaptation for the fungus that helps it cohabitate with the bees,” Bush said. “We suspect that there is some mutual benefit to both organisms, but we haven’t found sufficient evidence yet.” The researchers are now hoping to study how the fungus performs on different compositions of bee bread during their life cycle. They hope that their work will shed light on how fungicides that are routinely used to protect the bee hives will affect these microbes. Reference: “An Aspergillus flavus strain from bee bread of the Western honey bee (Apis mellifera) displays adaptations to distinctive features of the hive environment” by Daniel S. Bush, Bernarda Calla and May R. Berenbaum, 22 February 2024, Ecology and Evolution. DOI: 10.1002/ece3.10918 The study was supported by the Agriculture and Food Research Initiative.

A Naupactus cervinus weevil, a common, yet invasive species in many parts of the world, is seen eating a leaf. Credit: Courtesy of Analia Lanteri/Facultad de Ciencias Naturales y Museo de La Plata, Argentina Research from Wellesley College shows that despite being a clonal insect species, weevils use gene regulation to adapt to new food sources and pass down epigenetic changes to future generations. Without the benefits of evolutionary genetic variation that accompany meiotic reproduction, how does an asexual invasive species adapt over time to a new environment to survive? In all-female weevil species that produce only female offspring from unfertilized eggs, the insects’ survival techniques have led to the surprising discovery that these creatures can pass down gene regulation changes to future generations.  New research from Wellesley College has found that two types of weevils, common yet invasive beetles in many parts of the world, have been using epigenetic changes to adapt and respond to different toxins in the plants they eat. The findings, published in PLOS ONE under the title “Host-Specific Gene Expression as a Tool for Introduction Success in Naupactus Parthenogenetic Weevils,” have implications for how we consider asexual invaders and how successful they can be because of gene regulation.  The researchers, led by Andrea Sequeira, Wellesley College Gordon and Althea Lang ’26 Professor of Biological Sciences, collected samples of parthenogenetic, invasive, and polyphagous weevils, Naupactus cervinus and N. leucoloma, from Florida, California, and Argentina over the course of five years, starting in 2015. Despite being from different locations within the United States where they have been introduced, often through commerce, the weevils are asexual and genetically identical. Yet the team found that they have uniquely adapted to produce different proteins that allow them to eat and digest a variety of plants, even those that produce toxins. Sequeira worked with a talented team: Ava Mackay-Smith, Mary Kate Dornon, Rosalind Lucier, Anna Okimoto, and Flavia Mendonca de Sousa from Wellesley College, and Marcela Rodriguero, Viviana Confalonieri, Analia Lanteri from the University of Buenos Aires and the Museo de Ciencias Naturales in La Plata, Argentina. Together, they analyzed patterns of gene expression in three gene categories that can mediate weevil-host plant interactions through identification of suitable host plants, short-term acclimation to host plant defenses, and long-term adaptation to host plant defenses and their pathogens. “We found that some host plant groups, such as legumes, appear to be more taxing for weevils and elicit a complex gene expression response,” Sequeira said. “However, the weevil response to taxing host plants shares many differentially expressed genes with other stressful situations, such as organic cultivation conditions and transition to novel hosts, suggesting that there is an evolutionarily favorable shared gene expression regime for responding to different types of stressful situations.” “We also found that mothers are able to ‘prime’ their young with these epigenetic changes,” lead author and 2020 Wellesley College alumna Ava Mackay-Smith said. “Originally, we thought that these changes would only be seen in a single generation. When we studied larvae, who do not yet have mouths or eat plants, we found evidence of the same proteins and adaptations from their mothers.”  Sequeira noted this finding is especially important because classic understanding has been that in both sexual and asexual reproduction, all epigenetic marks are erased between generations and each generation starts over. “These mothers are essentially giving their offspring a pep talk, and preparing them for the harsh realities of the herbivorous insect world, by passing down these gene regulation ‘tips’ from one generation to the next.”  Mackay-Smith believes that having a better understanding of epigenetic changes in invasive, asexual species may eventually help regulate or mitigate their potential negative impact on an environment, native plants, or crops, for example. “Knowing what is in this insect’s repertoire, you could imagine that since we’ve now identified the proteins that are regulated differently, you could target a specific protein and design a targeted pesticide that removes only that species of weevil, without harming other native insects or fauna.”  Both Mackay-Smith and Sequeira are excited to see that perhaps genetic variation is not the only form of heritable variation for natural selection to act upon and that epigenetic processes may increase the evolutionary potential of organisms in response to stress and other environmental challenges—adaptations that could be relevant in the context of climate change. Reference: “Host-specific gene expression as a tool for introduction success in Naupactus parthenogenetic weevils” by Ava Mackay-Smith, Mary Kate Dornon, Rosalind Lucier, Anna Okimoto, Flavia Mendonca de Sousa, Marcela Rodriguero, Viviana Confalonieri, Analia A. Lanteri and Andrea S. Sequeira, 30 July 2021, PLOS ONE. DOI: 10.1371/journal.pone.0248202

Stanford researchers discovered that certain cyanobacteria possess both forms of the enzyme RuBisCo, a rare combination that may enhance their ability to store carbon efficiently, particularly in low-oxygen ocean zones. This finding sheds light on how these microbes adapt to challenging environments and could have implications for ocean carbon storage and crop engineering. Stanford researchers have identified multiple forms of a ubiquitous enzyme in microbes that flourish in low-oxygen regions along the coasts of Central and South America. Stanford researchers have discovered a fascinating genetic anomaly in a type of microbe that could significantly influence ocean carbon storage. These microbes, commonly called blue-green algae or cyanobacteria, have two different forms of a ubiquitous enzyme that rarely appear together in the same organism. “This is one of those great examples of science where you go out looking for one thing, but you end up finding something else that’s even better,” said Anne Dekas, an assistant professor of Earth system science at the Stanford Doerr School of Sustainability and senior author of the Nov. 25 study in Proceedings of the National Academy of Sciences. Crew members and Stanford scientists aboard a research cruise prepare a rosette of bottles that will descend into the ocean to capture water for DNA analysis. Similar sampling methods provided the data used in the study. Credit: Anne Dekas Billions of years ago, long before plants arrived on the scene, cyanobacteria invented oxygenic photosynthesis. In the process of producing food from carbon dioxide and sunlight, the widespread microbes released oxygen into the air, making our planet’s atmosphere hospitable to the array of life on Earth today. “Cyanobacteria are arguably the most important life form on Earth,” said Dekas. “They oxygenated the atmosphere of Earth and created a biological revolution.” Special cyanobacteria Like plants, cyanobacteria use an enzyme called ribulose bisphosphate carboxylase, or RuBisCo, to convert carbon dioxide into biomass. One of the most abundant proteins in nature, RuBisCo comes in several forms: The most common type, known as form I RuBisCo, often uses a structure called a carboxysome to selectively react with carbon dioxide but not oxygen, allowing photosynthesis to proceed efficiently. Organisms with a less common type of the enzyme, known as form II, lack a carboxysome and can effectively build biomass from carbon dioxide in environments where oxygen is scarce. Bottles containing ocean samples from deep underwater are hauled back to the surface. Credit: Anne Dekas Usually, organisms have only one form of RuBisCo, said lead author Alex Jaffe, a postdoctoral scholar in Earth system science. So he was surprised when he happened upon an exception to that rule while studying carbon fixation in ocean microbes. Jaffe was analyzing DNA from seawater samples collected from deep waters off the coasts of Central and South America when he noticed that some shallow water DNA samples had accidentally slipped in. He discovered that cyanobacteria in these samples seemed to have genes for both RuBisCo forms. “My initial reaction was this is probably wrong,” said Jaffe. Further research confirmed that both forms of the enzyme were present and actively used for photosynthesis in the cyanobacteria from shallow water, although additional testing will be required to understand how cyanobacteria use the two forms. “By having two versions,” said Jaffe, “it might allow you to remove more carbon dioxide from the water than if you only had one of them, or potentially to do it a little bit more efficiently.” Efficiency might be key to survival where the samples originated, in an oxygen minimum zone about 50 to 150 meters below the surface, where oxygen and light are both in short supply. “It’s very hard to live there,” said Dekas. “For a photosynthetic organism, when you have low light, you have little energy.” Carbon storage and extra-efficient crops The findings could help scientists anticipate how the ocean’s capacity to sequester carbon may shift as climate change expands low-oxygen zones. The revelation that some cyanobacteria have both forms of RuBisCo suggests they may store carbon more efficiently than previously understood and could proliferate along with expanding oxygen minimum zones. Researchers from Dekas Geomicrobiology Laboratory drain freshly collected seawater, which they will analyze aboard the research vessel, from large sample bottles into smaller tubes. Credit: Anne Dekas If two RuBisCos are in fact better than one, the finding could also lead to more efficient crop production. For decades, researchers have tried to engineer form I RuBisCo to enable crops that grow more with less fertilizer and water. “We’re looking forward to continuing to think about this with people who work on the plant engineering side to see whether it might yield some fruit, literally and metaphorically,” said Jaffe. The findings gave Jaffe a new appreciation for life’s ability to adapt to challenging environments. “These genes, despite being central to organisms’ metabolism, can actually be quite flexible and can be reconfigured and shuffled in ways that we didn’t expect,” he said. Reference: “Cyanobacteria from marine oxygen-deficient zones encode both form I and form II Rubiscos” by Alexander L. Jaffe, Kaitlin Harrison, Renée Z. Wang, Leah J. Taylor-Kearney, Navami Jain, Noam Prywes, Patrick M. Shih, Jodi Young, Gabrielle Rocap and Anne E. Dekas, 25 November 2024, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2418345121 This research was funded by the Stanford Science Fellows program, the National Science Foundation, and the Simons Foundation.

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