Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Indonesia ergonomic pillow OEM supplier

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Latex pillow OEM production in China

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.ODM service for ergonomic pillows Vietnam

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Breathable insole ODM development Vietnam

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.One-stop OEM/ODM solution provider Thailand

Harem stallions fight for the females and protect their harems against predators and the bachelor males, which are non-breeding males without a harem. Credit: Katalin Ozogány The findings reveal that wild horses,  just like humans, live in a complex, multilevel society. The organization and even past and future shifts in group dynamics can be deciphered using high-definition aerial footage. Researchers from the Hungarian Research Network (HUN-REN), the University of Debrecen (UD), the Eötvös Loránd University (ELTE), and the Hortobágy National Park Directorate studied the social dynamics of the Przewalski’s horse herd in Hortobágy. They utilized drone technology combined with extensive population monitoring data for their analysis. By deploying two drones, the team meticulously monitored the movements of the herd of 278 Przewalski’s horses with high temporal and spatial resolution, while individually identifying most of the animals. The results show that wild horses, just like humans, live in a complex, multilevel society, the structure of which ‒ and even group changes in the past and future ‒ can be understood with the help of high-resolution aerial videos. The paper presenting the research was published in the prestigious scientific journal Nature Communications. In Hortobágy National Park, Hungary, harems of Przewalski’s horses come together to form a large multilevel herd. Each harem consists of a single male – the harem stallion – and several females and their juvenile offspring. Credit: Katalin Ozogány Investigating the social behavior of a large group of animals is time-consuming work if one uses classical observation methods. However, the study published in Nature Communications highlights that by collecting high-resolution data, even a few minutes of footage of animal movements can provide enough information to learn about the social structure of the population and even draw conclusions about the past and future dynamics of the group. “We wanted to investigate the group movements of the Przewalski’s horse herd in Hortobágy, Hungary. However, observing nearly 300 horses at the same time is not an easy task,” says Katalin Ozogány, the first author of the study, a member of the HUN-REN–UD Behavioural Ecology Research Group of the Hungarian Research Network and the University of Debrecen (Hungary). “We took aerial videos of the herd using drones while they were moving around the reserve, and based on the footage, we determined the movement routes of all the individuals of the herd with high spatiotemporal resolution.” Multilevel Societies The multilevel social structure that is also characteristic of humans is rare in animals. It is mainly found in primates but also occurs in cetaceans, elephants, and some ungulates that individuals form smaller family groups (for example harems or a group of related females led by a matriarch), and these family groups form a larger, looser community. youtube.com/watch?v=H2BhFjEbZDE Video abstract of the research. Credit: University of Debreceni Przewalski’s horses have been living in Hortobágy since 1997 in the Pentezug reserve. In the first years after founding the population, the harems of wild horses lived in their own home ranges and rarely interacted with each other. For over a decade, however, the harems together form a large herd, in which harems can still be distinguished, but they move together in the reserve. The researchers studied the group movements of this complex herd, made up of harems. Analysis of Collective Movements Reveals Social Behavior Analysis of the herd’s movements yielded surprising results. “The individuals of the group coordinate their movements and align with each other, and by detecting these fine interactions between the individuals, it turned out that we can assess the herd’s social network based on the group movements,” explains lead author Máté Nagy, head of the Collective Behaviour ‘Lendület’ Research Group of the Hungarian Academy of Sciences and Eötvös Loránd University (Hungary). Przewalski’s horses are the last living subspecies of wild horses, native to Mongolia. Their Mongolian name “takhi” means “spirit”. Credit: Katalin Ozogány The researchers combined the short-term movement observations of a few minutes with the long-term population monitoring data of the national park going back two decades. Since the establishment of the reserve, the wild horses have been individually recognized by the park staff who regularly collected data on population changes. “Thanks to population monitoring, we know the parentage of the animals, which we also confirm with genetic sampling, as well as their place in the social system, that is, we regularly record which individual belongs to which harem,” says co-author Viola Kerekes, project leader of the Hortobágy National Park Directorate. The Herd’s Social Network The analyses showed that the social relations of wild horses are related to kinship and familiarity of the animals. For example, female horses (mares) are closer to each other in the social network if they have been harem mates for a longer time. Kinship may play a significant role in the organization of harems into herds since harems of sibling stallions (the single breeding male in a harem) are closer to each other in the social network than harems of unrelated stallions. Between the closer harems, at the same time, the dispersal of mares was greater, which also contributes to the relations between harems through familiarity. “It is an exceptional opportunity to explore the social network of an entire population and its dynamics,” explains co-author Attila Fülöp, a researcher at the Babeş-Bolyai University (Romania) and the HUN-REN–UD Behavioural Ecology Research Group. It turned out that older and larger harems, which typically belong to older and more experienced stallions, occupy more central locations in the herd’s social network. A possible explanation is that harem stallions form an alliance to protect their harems more effectively against the bachelor males. Future Group Dynamics “One of the surprising outcomes of the study is that we can infer future group dynamics by observing current movement,” adds Zoltán Barta, lead author, head of the Department of Evolutionary Zoology of the University of Debrecen and the HUN-REN–UD Behavioural Ecology Research Group. The researchers showed that mares that lived in different harems at the time of the aerial observations but became harem mates within two years after the observations, were already moving in more similar routes than the other mares. So, through the movement analysis, it was also possible to conclude which mares will leave their harem in the next two years and which harem they will transfer to. “Not only did we learn new, previously unknown details about the social life of Przewalski’s horses, but we highlighted that drone observations, which can be applied even in wild populations, can provide very detailed information.” Reference: “Fine-scale collective movements reveal present, past and future dynamics of a multilevel society in Przewalski’s horses” by Katalin Ozogány, Viola Kerekes, Attila Fülöp, Zoltán Barta and Máté Nagy, 5 September 2023, Nature Communications. DOI: 10.1038/s41467-023-40523-3

Scientists characterize previously unknown gut reactions. Strictly speaking, humans cannot digest complex carbohydrates — that’s the job of bacteria in our large intestines. UC Riverside scientists have just discovered a new group of viruses that attack these bacteria. The viruses, and the way they evade counterattack by their bacterial hosts, are described in a paper published in Cell Reports. Bacterioides can constitute up to 60% of all the bacteria living in a human’s large intestine, and they’re an important way that people get energy. Without them, we’d have a hard time digesting bread, beans, vegetables, or other favorite foods. Given their significance, it is surprising that scientists know so little about viruses that prey on Bacteroides.  “This is largely unexplored territory,” said microbiologist Patrick Degnan, an assistant professor of microbiology and plant pathology, who led the research.  To find a virus that attacks Bacteroides, Degnan and his team analyzed a collection of bacterial genomes, where viruses can hide for numerous generations until something triggers them to replicate, attack, and leave their host. This viral lifestyle is not without risk as over time mutations could occur that prevent the virus from escaping its host. On analyzing the genome of Bacteroides vulgatus, Degnan’s team found DNA belonging to a virus they named BV01. However, determining whether the virus is capable of escaping, or re-infecting its host, proved challenging. Reconstructed microscopy image of a bacteriophage, which is a virus that attacks bacteria. Credit: Purdue University and Seyet LLC “We tried every trick we could think of. Nothing in the laboratory worked until we worked with a germ-free mouse model,” Degnan said. “Then, the virus jumped.”  This was possible due to Degnan’s collaboration with UCR colleague, co-author and fellow microbiologist Ansel Hsiao. This result suggests conditions in mammalian guts act as a trigger for BV01 activity. The finding underscores the importance of both in vitro and in vivo experiments for understanding the biology of microbes.  Looking for more information about the indirect effect of this bacterial virus might have on humans, Degnan’s team determined that when BV01 infects a host cell, it disrupts how that cell normally behaves.  “Over 100 genes change how they get expressed after infection,” Degnan said.  Two of the altered genes that stood out to the researchers are both responsible for deactivating bile acids, which are toxic to microbes. The authors speculate that while this possibly alters the sensitivity of the bacteria to bile acids, it also may influence the ability of the bacteria to be infected by other viruses. “This virus can go in and change the metabolism of these bacteria in human guts that are so key for our own metabolism,” Degnan said.  Though the full extent of BV01 infection is not yet known, scientists believe viruses that change the abundance and activity of gut bacteria contribute to human health and disease. One area for future studies will involve the effect of diet on BV01 and viruses like it, as certain foods can cause our bodies to release more bile. Degnan also notes that BV01 is only one of a group of viruses his team identified that function in similar ways. The group, Salyersviridae, is named after famed microbiologist Abigail Salyers whose work on intestinal bacteria furthered the science of antibiotic resistance. Further research is planned to understand the biology of these viruses.  “It’s been sitting in plain sight, but no one has characterized this important group of viruses that affect what’s in our guts until now,” Degnan said. Reference: “Infection with Bacteroides Phage BV01 Alters the Host Transcriptome and Bile Acid Metabolism in a Common Human Gut Microbe” by Danielle E. Campbell, Lindsey K. Ly and Jason M. R, 15 September 2020, Cell Reports. DOI: 10.1016/j.celrep.2020.108142

Researchers at UNSW Sydney have discovered novel mechanisms of sex chromosome dosage compensation in platypus and chicken, challenging previous assumptions and providing new insights into genetic regulation across species. A new study reveals that platypuses and chickens balance protein levels between sexes through a unique dosage compensation mechanism, different from humans, challenging long-standing genetic assumptions and enhancing our understanding of genetic evolution and regulation. Researchers at UNSW Sydney have uncovered fundamental differences in biological processes between males and females by examining the unique and diverse sex chromosome systems of the platypus and the chicken. The findings, published in Proceedings of the National Academy of Sciences (PNAS), are a surprise in the field of genetics. The discoveries will help build a better understanding of how sex chromosomes evolved, how our bodies function—and they could lead to new discoveries in biology. “Mammals, such as humans, have females with two X chromosomes and males with one X chromosome and one Y chromosome, which creates an imbalance between the sexes,” says lead author Dr Nicholas Lister from UNSW’s School of Biotechnology and Biomolecular Sciences. “This imbalance is corrected by a process called sex chromosome dosage compensation.” Scientists have long known that animals have solutions to balance sex chromosome differences and achieve ‘normal’ function. Dr Lister says: “In female mammals, such as humans and mice, XX females and XY males have different numbers of the X chromosome. To balance this difference, one of the X chromosomes in females is typically silenced. Silencing one X chromosome in females equalizes the gene products on the sex chromosomes. This prevents females from producing double the number of proteins from the X compared to males.” Balancing the scales Every cell in our bodies uses proteins to perform specific functions. “They are translated from mRNA, which carry the instructions for cells to make proteins,” the study’s research lead, Associate Professor Paul Waters, also from UNSW’s School of Biotechnology and Biomolecular Sciences, says. “Being male or female affects mRNA levels of X chromosome genes, which we would then expect to affect protein production.” The platypus and chicken have vastly different sex chromosome systems to humans—which can give us valuable insights into our own bodies work. Credit: Shafagh Waters and Lisa Melisa But A/Prof. Waters says this study demonstrates—for the first time—that a balance of proteins occurs between the sexes, even when mRNA levels aren’t balanced. “The findings suggest that dosage compensation is a crucial process in species with differentiated sex chromosomes to ensure that protein levels are balanced,” he says. “These results are significant as they suggest that dosage compensation of sex chromosomes is essential after all—and across all vertebrate species, not just placental and marsupial mammals.” Why the platypus and the chicken? The study focused on the platypus and the chicken—two species with vastly different sex chromosome systems that offer valuable insights into the evolution and mechanisms of dosage compensation. “Platypus are monotreme mammals, with interesting sex chromosome systems,” Dr Lister says. “They have five pairs of X chromosomes in females and five Xs and five Ys in males. Birds—such as chickens—have a ZW system, where males have two copies of a Z chromosome and females have a Z and a W chromosome.” A/Prof. Waters says the scientists had already observed near-perfect sex chromosome dosage compensation of RNA between males and females in placental and marsupial mammals. “However, in birds and monotremes, there is an imbalance of mRNA between the sexes,” he says. “This is something we thought was impossible. For the first time, we show that this imbalance is corrected at the protein level. This means that platypus and chicken have a novel mechanism of dosage compensation that is different from how we humans do it.” Are our genes really in control? Co-author Professor Jenny Graves, from the Department of Environment and Genetics at La Trobe University, had demonstrated that genes on the inactive human X chromosome are not copied into RNA back in 1986. Silencing at the level of RNA then became the paradigm for all epigenetic silencing. “As the genes were silenced by their failure to make RNA, the control of dosage compensation was assumed to be at the level of RNA only—not at the level of making proteins,” Prof. Graves says. “But mRNA levels for genes on sex chromosomes weren’t balanced in the platypus or the chicken,” she says. “So, scientists questioned the assumption that dosage compensation is essential for life.” A/Prof. Waters says that measuring protein levels has been a much trickier endeavor than measuring mRNA levels, due to technological challenges. “And now that the technology is more sensitive, we can see that the dosage compensation of sex chromosomes between males and females is observed at the protein level in the platypus and the chicken,” A/Prof. Waters says. “The males and females of these species make similar amounts of proteins, despite the discrepancies in mRNA quantities.” How will this knowledge be applied? The authors emphasize the complexity of genetic regulation and the importance of considering multiple levels of control in gene expression. Co-author Dr Shafagh Waters from UNSW’s School of Biomedical Sciences says the study paves the way for a deeper understanding of genetic regulation. “Studying unique species like the platypus provides us with new insights into the cellular and molecular mechanisms that could regulate various aspects of human physiology, or be implicated in disease states,” she says. “So, while these processes may not directly apply to human dosage compensation, they illuminate how our bodies manage gene expression and protein production. Our findings have the potential to advance knowledge in evolutionary biology and lead to innovative therapies in medical genetics. Understanding these mechanisms across different species can help identify new targets for diseases where protein dysfunction is key.” Dr Lister says future research will examine the mechanisms that contribute to dosage compensation. “This work will help us discover other dosage compensation systems in nature,” he says. “We can find out how these evolved and how they work in other species.” A/Prof. Waters says, “Understanding these processes in other species can enhance our grasp of gene regulation at a fundamental level.” Reference: “Incomplete transcriptional dosage compensation of chicken and platypus sex chromosomes is balanced by post-transcriptional compensation” by Nicholas C. Lister, Ashley M. Milton, Hardip R. Patel, Shafagh A. Waters, Benjamin J. Hanrahan, Kim L. McIntyre, Alexandra M. Livernois, William B. Horspool, Lee Kian Wee, Alessa R. Ringel, Stefan Mundlos, Michael I. Robson, Linda Shearwin-Whyatt, Frank Grützner, Jennifer A. Marshall Graves, Aurora Ruiz-Herrera and Paul D. Waters, 29 July 2024, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2322360121

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