Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw

Custom graphene foam processing Taiwan

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Indonesia orthopedic insole OEM manufacturer

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Innovative insole ODM solutions in Vietnam

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Graphene insole OEM factory China

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.PU insole OEM production factory in Taiwan

In warming waters, the demand for oxygen of many fish species will increase, progressively approaching the maximum oxygen supply capacity of their respiratory organs. New Tool Gauges Impacts of Warming Waters on Over 200 Fish Species Warming ocean waters could reduce the ability of fish, especially large ones, to extract the oxygen they need from their environment. Animals require oxygen to generate energy for movement, growth, and reproduction. In a recent paper in the Proceedings of the National Academy of Science, an international team of researchers from McGill, Montana and Radboud universities describe their newly developed model to determine how water temperature, oxygen availability, body size, and activity affect metabolic demand for oxygen in fish. The model is based on physicochemical principles that look at oxygen consumption and diffusion at the gill surface in relation to water temperature and body size. Predictions were compared against actual measurements from over 200 fish species where oxygen consumption rates were measured at different water temperatures and across individuals of different body sizes. Fish Will Need More Oxygen Than Their Gills Can Extract From Warming Water “Our data suggest that, as temperature increases, the demand for oxygen of many fish species will exceed their capacity to extract oxygen from the environment through their gills,” explains Juan Rubalcaba, a Marie Skłodowska-Curie Postdoctoral Fellow at McGill, and lead author on the paper. “As a result, the aerobic capacity of fish decreases in warming waters, and this reduction may be more important in larger fishes. This tells us that global warming could limit the aerobic capacity of fish, impairing their physiological performance in the future.” “Water temperature is already rising worldwide as a consequence of climate change and many fish species need to cope with this rapid temperature change, either by migrating toward colder regions or by adopting different life strategies such as shrinking in size over generations in order to avoid respiratory constraints,” said Art Woods, a professor of biological sciences at the University of Montana, and the senior author on the paper. “By including oxygen, this model stands apart by predicting observed patterns of variation in metabolic rate among fishes worldwide than current theories, which focus primarily on body size and temperature.” Reference: “Oxygen limitation may affect the temperature and size dependence of metabolism in aquatic ectotherms” by Juan G. Rubalcaba, Wilco C. E. P. Verberk, A. Jan Hendriks, Bart Saris and H. Arthur Woods, 30 November 2020, Proceedings of the National Academy of Science. DOI: 10.1073/pnas.2003292117 The research was funded by the European Commission’s Marie Skłodowska-Curie Individual Fellowship

A recent study suggests that the primary components of life on Earth may have originated from solar eruptions. The research demonstrated that solar particles colliding with gases in Earth’s primitive atmosphere could produce amino acids and carboxylic acids, the fundamental elements of proteins and organic life. Using data from NASA’s Kepler mission, researchers proposed that energetic particles from the sun, during its early superflare stage, would regularly interact with our atmosphere, triggering essential chemical reactions. Experimental replications indicated that solar particles appear to be a more efficient energy source than lightning for the formation of amino acids and carboxylic acids. Credit: NASA/Goddard Space Flight Center A new study posits that the earliest building blocks of life on Earth, namely amino acids and carboxylic acids, may have been formed due to solar eruptions. The research suggests that energetic particles from the sun during its early stages, colliding with Earth’s primitive atmosphere, could have efficiently catalyzed essential chemical reactions, thus challenging the traditional “warm little pond” theory. The first building blocks of life on Earth may have formed thanks to eruptions from our Sun, a new study finds. A series of chemical experiments show how solar particles, colliding with gases in Earth’s early atmosphere, can form amino acids and carboxylic acids, the basic building blocks of proteins and organic life. The findings were published in the journal Life. To understand the origins of life, many scientists try to explain how amino acids, the raw materials from which proteins and all cellular life, were formed. The best-known proposal originated in the late 1800s as scientists speculated that life might have begun in a “warm little pond”: A soup of chemicals, energized by lightning, heat, and other energy sources, that could mix together in concentrated amounts to form organic molecules. Artist’s concept of Early Earth. Credit: NASA In 1953, Stanley Miller of the University of Chicago tried to recreate these primordial conditions in the lab. Miller filled a closed chamber with methane, ammonia, water, and molecular hydrogen – gases thought to be prevalent in Earth’s early atmosphere – and repeatedly ignited an electrical spark to simulate lightning. A week later, Miller and his graduate advisor Harold Urey analyzed the chamber’s contents and found that 20 different amino acids had formed. “That was a big revelation,” said Vladimir Airapetian, a stellar astrophysicist at NASA’s Goddard Space Flight Center in Greenbelt, Maryland, and coauthor of the new paper. “From the basic components of early Earth’s atmosphere, you can synthesize these complex organic molecules.” But the last 70 years have complicated this interpretation. Scientists now believe ammonia (NH3) and methane (CH4) were far less abundant; instead, Earth’s air was filled with carbon dioxide (CO2) and molecular nitrogen (N2), which require more energy to break down. These gases can still yield amino acids, but in greatly reduced quantities. Seeking alternative energy sources, some scientists pointed to shockwaves from incoming meteors. Others cited solar ultraviolet radiation. Airapetian, using data from NASA’s Kepler mission, pointed to a new idea: energetic particles from our Sun. Kepler observed far-off stars at different stages in their lifecycle, but its data provides hints about our Sun’s past. In 2016, Airapetian published a study suggesting that during Earth’s first 100 million years, the Sun was about 30% dimmer. But solar “superflares” – powerful eruptions we only see once every 100 years or so today – would have erupted once every 3-10 days. These superflares launch near-light speed particles that would regularly collide with our atmosphere, kickstarting chemical reactions. Energy from our young Sun – 4 billion years ago – aided in creating molecules in Earth’s atmosphere that allowed it to warm up enough to incubate life. Credit: NASA’s Goddard Space Flight Center/Genna Duberstein “As soon as I published that paper, the team from the Yokohama National University from Japan contacted me,” Airapetian said. Dr. Kobayashi, a professor of chemistry there, had spent the last 30 years studying prebiotic chemistry. He was trying to understand how galactic cosmic rays – incoming particles from outside our solar system – could have affected early Earth’s atmosphere. “Most investigators ignore galactic cosmic rays because they require specialized equipment, like particle accelerators,” Kobayashi said. “I was fortunate enough to have access to several of them near our facilities.” Minor tweaks to Kobayashi’s experimental setup could put Airapetian’s ideas to the test. Proton Power vs. Lightning Energy Airapetian, Kobayashi, and their collaborators created a mixture of gases matching early Earth’s atmosphere as we understand it today. They combined carbon dioxide, molecular nitrogen, water, and a variable amount of methane. (The methane proportion in Earth’s early atmosphere is uncertain but thought to be low.) They shot the gas mixtures with protons (simulating solar particles) or ignited them with spark discharges (simulating lightning), replicating the Miller-Urey experiment for comparison. As long as the methane proportion was over 0.5%, the mixtures shot by protons (solar particles) produced detectable amounts of amino acids and carboxylic acids. But the spark discharges (lightning) required about a 15% methane concentration before any amino acids formed at all. “And even at 15% methane, the production rate of the amino acids by lightning is a million times less than by protons,” Airapetian added. Protons also tended to produce more carboxylic acids (a precursor of amino acids) than those ignited by spark discharges. A close up of a solar eruption, including a solar flare, a coronal mass ejection, and a solar energetic particle event. Credit: NASA’s Goddard Space Flight Center All else being equal, solar particles appear to be a more efficient energy source than lightning. But all else likely wasn’t equal, Airapetian suggested. Miller and Urey assumed that lightning was just as common at the time of the “warm little pond” as it is today. But lightning, which comes from thunderclouds formed by rising warm air, would have been rarer under a 30% dimmer Sun. “During cold conditions you never have lightning, and early Earth was under a pretty faint Sun,” Airapetian said. “That’s not saying that it couldn’t have come from lightning, but lightning seems less likely now, and solar particles seems more likely.” These experiments suggest our active young Sun could have catalyzed the precursors of life more easily, and perhaps earlier, than previously assumed. Reference: “Formation of Amino Acids and Carboxylic Acids in Weakly Reducing Planetary Atmospheres by Solar Energetic Particles from the Young Sun” by Kensei Kobayashi Jun-ichi Ise, Ryohei Aoki, Miei Kinoshita, Koki Naito, Takumi Udo, Bhagawati Kunwar, Jun-ichi Takahashi, Hiromi Shibata, Hajime Mita, Hitoshi Fukuda, Yoshiyuki Oguri, Kimitaka Kawamura, Yoko Kebukawa and Vladimir S. Airapetian, 28 April 2023, Life. DOI: 10.3390/life13051103

Astrocytes (yellow) detect when the mouse is spatially oriented and then increase the probability of dendritic spikes by signaling molecules. Credit: Dr. Kirsten Bohmbach/University Hospital Bonn Study at the University of Bonn elucidates previously unknown mechanism for spatial learning. There are two fundamentally different cell types in the brain, neurons, and glial cells. One purpose of the latter is to insulate the “wiring” of nerve cells or guarantee optimal working conditions for them. A new study led by the University of Bonn has now discovered another function in rodents: The results suggest that a certain type of glial cell plays an important role in spatial learning. The German Center for Neurodegenerative Diseases (DZNE) was involved in the work. The results have now been published in the journal Nature Communications. Each place has numerous characteristics that distinguish it and make it unmistakable as a whole. A gnarled tree. A babbling brook at its foot. Fragrant wildflowers in the meadow behind. When we visit a place for the first time, we store this combination of features. When we then encounter the interplay of tree, brook, and wildflower meadow another time, our brain recognizes it: We remember having been there before. This is made possible by mechanisms such as the so-called dendritic integration of synaptic activity. “We were able to show that the so-called astroglial cells or astrocytes play an essential role in this integration,” explains Prof. Dr. Christian Henneberger from the Institute of Cellular Neuroscience at the University Hospital Bonn. “They regulate how sensitive neurons are to a specific combination of features.” One Million Place Cells in the Mouse Brain In their study, the researchers took a close look at neurons in the hippocampus of rodents. The hippocampus is a region in the brain that plays a central role in memory processes. This is especially true for spatial memory: “In the hippocampus, there are neurons that specialize in just that — place cells,” says Henneberger, who is also a member of the Collaborative Research Center 1089 — where the research project was based — and the Transdisciplinary Research Area “Life & Health” at the University of Bonn. There are about one million of these place cells in the mouse hippocampus alone. Each responds to a specific combination of environmental characteristics. Place cells have long extensions, the dendrites. These are branched like the crown of a tree and dotted with numerous contact points. Information that our senses convey to us about a location arrives here. These contacts are called synapses. “When signals arrive at many neighboring synapses at the same time, a strong voltage pulse occurs in the dendrite — a so-called dendritic spike,” explains Dr. Kirsten Bohmbach, who performed most of the experiments in the study. “This process is what we call dendritic integration: The spike only occurs when a sufficient number of synapses are active at the same time. Such spikes travel toward the cell body, where they can trigger another voltage pulse — an action potential.” Place Cells in Attention Mode Place cells generate action potentials at regular intervals. The speed at which they do this can vary widely. However, when mice orient themselves in a new environment, their place cells always oscillate in a special rhythm — they then generate five to ten voltage pulses per second. This rhythm causes the nerve cells to release certain messenger substances. And this is where astrocytes come in: They have sensors to which these messenger substances dock, and in turn, release a substance called D-serine. “The D-serine then migrates to the dendrites of the place cells,” Bohmbach explains. “There, it ensures that the dendritic spikes can develop more easily and are also much stronger.” When mice are in orientation mode, this makes it easier for them to store and recognize new locations. It is similar to a cab driver concentrating on navigating through the city center and memorizing changing locations. The passenger next to the driver is also looking at the road, but his thoughts are elsewhere and he notices less (however, there are also quite different processes involved in such attention phenomena). “If we inhibit the assistance provided by astrocytes in mice, they are less likely to recognize familiar places,” Henneberger says. However, this does not apply to locations that are particularly relevant — for example, because they pose a potential danger: These continue to be avoided by the animals. “The mechanism we discovered therefore controls the threshold at which location information is stored or recognized.” The results provide a new insight into how memory works and is controlled. In the medium term, they may also help to answer the question of how certain forms of memory disorders develop. The research results are also an expression of fruitful intra-university cooperation: “They would not have been possible without the intensive collaboration with Prof. Dr. Heinz Beck’s laboratory at the Institute of Experimental Epileptology and Cognitive Sciences and, in particular, his colleagues Dr. Nicola Masala and Dr. Thoralf Opitz,” Henneberger highlights. Reference: “An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning” by Kirsten Bohmbach, Nicola Masala, Eva M. Schönhense, Katharina Hill, André N. Haubrich, Andreas Zimmer, Thoralf Opitz, Heinz Beck and Christian Henneberger, 24 December 2022, Nature Communications. DOI: 10.1038/s41467-022-35620-8 In addition to the University of Bonn and the University Hospital Bonn, the German Center for Neurodegenerative Diseases (DZNE) and University College London were involved in the work. The study was funded by the German Research Foundation (DFG) and the returnee program of the state of North Rhine-Westphalia.

DVDV1551RTWW78V