Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Indonesia insole ODM service provider

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Smart pillow ODM manufacturing factory Taiwan

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Ergonomic insole ODM support Vietnam

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Vietnam graphene sports insole ODM

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.One-stop OEM/ODM solution provider Thailand

Left: The organ of Corti from a normal (control) mouse. The hair cells and their support cells are lined up in an alternating, checkerboard-like pattern. Right: The organ of Corti from a nectin KO mouse. The top row of images were taken at 12 days old, the bottom row at 28 days old. 2 weeks after birth, the hair cells in nectin KO mice disappeared due to apoptosis (cell death). The white arrows indicate where hair cells became attached to each other. Credit: Katsunuma S, Togashi H, Kuno S, Fujita T and Nibu K-I (2022) Hearing loss in mice with disruption of auditory epithelial patterning in the cochlea. Front. Cell Dev. Biol. 10:1073830 Japanese researchers have uncovered the critical role of the checkerboard-like arrangement of hair and support cells in the organ of Corti in enabling hearing. A Japanese research group has become the first to reveal that the checkerboard-like arrangement of cells in the inner ear’s organ of Corti is vital for hearing. The discovery gives a new insight into how hearing works from the perspective of cell self-organization and will also enable various hearing loss disorders to be better understood. The research group included Assistant Professor Hideru Togashi of Kobe University’s Graduate School of Medicine and Dr. Sayaka Katsunuma of Hyogo Prefectural Kobe Children’s Hospital. These research results were published online in Frontiers in Cell and Developmental Biology on December 8, 2022. Main Points In the organ of Corti in the inner ear, there are two types of cells arranged in a checkerboard-like mosaic pattern; hair cells responsible for hearing and their support cells. However, the relationship between this checkerboard pattern and hearing function has long remained unclear. In mice in which the cells in the organ of Corti could not form into this checkerboard pattern, only the hair cells died (apoptosis), which resulted in deafness. For the first time in the world, it was understood that the checkerboard layout plays a fundamental structural role in preserving hair cells and their functionality as the arrangement prevents hair cells from adhering to each other. This mosaic pattern of cells has been observed in various sensory organs in many different kinds of animals. Understanding the mechanism behind how cell self-organization forms these mosaic patterns will help illuminate the functions of a variety of sensory organs and the mechanisms behind disorders. Research Background The inner ear cochlea is necessary for hearing sound, and located inside it is the organ of Corti (*1). When the organ of Corti is viewed from above under a microscope, two types of cells arranged in a precisely ordered layout resembling a chess or checkerboard can be seen. Hair cells that convey sound waves to the brain are separated by support cells, which prevent the hair cells from touching each other. Although it has been thought that this checkerboard arrangement is necessary for the organ of Corti to function properly, the relationship between this pattern and hearing function has long remained unclear. This research group previously revealed that this inner ear checkerboard is formed by a cellular segregation mechanism that enables the hair cells and support cells to move into line correctly. Hair cells and support cells each express a different type of the cell adhesion molecule nectin. This results in a hair cell and a support cell adhering more strongly to each other than two hair cells or two support cells would. This property is what causes hair cells and support cells to be arranged in a checkerboard pattern. In a mouse model where one of these nectin molecules is not functional, the properties change and the checkerboard pattern cannot form correctly. In this study, the researchers used these mice to investigate the connection between the checkerboard arrangement of cells and hearing functionality. Research Methodology The research group compared regular (control) mice to mice with one type of nectin not functioning correctly (nectin-3 KO mouse, referred to as nectin KO mouse below). No difference between the mice was observed in the number of hair cells and support cells in the organ of Corti immediately after birth. However, there was a difference in how easily the two types of cell adhere to each other; in the nectin-3 KO mice hair cells adhere together (which does not normally happen) resulting in abnormalities in the checkerboard pattern. At this point, the researchers hypothesized that testing the hearing of these mice might reveal the relationship between hearing and the checkerboard pattern. They measured the hearing of over one-month-old nectin KO mice using the auditory brainstem response (ABR) method (*2). This test revealed that the nectin KO mice were moderately deaf, demonstrating that this hearing loss was caused by the abnormalities in the inner ear. The researchers then examined the organs of Corti of the nectin KO mice that underwent the ABR test and found that the number of hair cells had decreased by approximately half. Next they set out to find out why only the hair cells (and not the support cells) had disappeared. They discovered that after 2 weeks of age, hair cell apoptosis (*3) occurred.  In addition, examination of the traces of apoptosis revealed that cell death occurred in many cells that had adhered to each other. This led the researchers to suppose that the hair cells adhering to each other (which does not normally happen) caused the apoptosis. In the epithelial tissue, which also includes the organ of Corti, there are tight junctions between each cell. These tight junctions not only connect the cells, they also prevent various molecules (including ions) from passing between the cells. If the organ of Corti doesn’t have these tight junctions, hair cells cannot function properly, cells die and hearing loss occurs. In nectin KO mice, tight junctions were not formed properly in the places where hair cells adhered together. However, tight junctions did correctly form in between hair cells and support cells. As long as two hair cells were not adhered together, normal cell function remained. In other words, hair cell apoptosis was induced only in the places where hair cells were abnormally adhered to each other and tight junctions did not form correctly. These results revealed for the first time that the checkerboard pattern of hair cells and support cells found in the organ of Corti functions as a fundamental structure, which protects hair cells and their functionality, by preventing hair cells from becoming attached to each other. Further Research Nectin is the causal gene for Margarita Island ectodermal dysplasia (*4). In addition to a cleft lip or palate and intellectual disabilities, deafness has also been reported in some cases of this genetic disorder. Therefore, the results of the current study might provide a new explanation for some cases of deafness where the cause is unclear. This study focused on hearing and demonstrated the physiological significance of the checkerboard-like mosaic pattern of cells in the organ of Corti. However other sensory cells that respond to outside stimuli and their respective supporter cells are also arranged in the same kind of alternating mosaic pattern. These mosaic patterns are found in sensory organs, such as the olfactory epithelium that is responsible for the sense of smell and the retina which is responsible for vision. The fact that these mosaic patterns are not only found in mammals but also in a variety of other organisms suggests that they are functionally important. The mosaic patterns in sensory tissues are created by self-organization due to the differences in adhesiveness between cells. Therefore, focusing research on cellular self-organization in sensory organs will increase our knowledge of the functions of sensory organs and advance our understanding of various related diseases. Glossary Organ of Corti: The sensory organ responsible for hearing. It is located inside the cochlea in the inner ear. Auditory brainstem response (ABR): A method of recording the brain waves that are generated when sound is heard. ABR is not only used to test the hearing of newborn human babies, it can also be used on mice and other animals. Apoptosis: A form of programmed cell death or cellular suicide that occurs in multicellular organisms. Margarita Island ectodermal dysplasia: A genetic disorder caused by mutations in the nectin-1 gene. The main manifestation is a cleft lip or palate accompanied by intellectual disability. Reference “Hearing loss in mice with disruption of auditory epithelial patterning in the cochlea” by Sayaka Katsunuma, Hideru Togashi, Shuhei Kuno, Takeshi Fujita and Ken-Ichi Nibu, 8 December 2022, Frontiers in Cell and Developmental Biology. DOI: 10.3389/fcell.2022.1073830 Acknowledgments This research received funding from the following organizations: KAKENHI grants from the Japan Society for the Promotion of Science (JSPS) (grant numbers: 18H04764, 18K09319, 19H04965, 22K19331), the Japan Science and Technology Agency’s Presto program (JPMJPR1946) and the Takeda Science Foundation.

Male cockroaches attract females by providing a roach version of chocolate – sugars and fats. Glucose-averse females, however, sometimes flee when their saliva turns the sweet treat into a bitter pill. Credit: Ayako Wada-Katsumata The Cockroach Mating Ritual and Its Sweet Surprise New research from North Carolina State University (NC State) shows the behavioral mechanism behind a sweet cockroach mating ritual that takes a bitter turn, resulting in rejected males. Male German cockroaches (Blattella germanica) offer females a pre-mating “gift” of body secretions that combine sugars and fats – think of the roach version of chocolate – in order to attract and hold female attention long enough to start copulation. “This is common mating behavior in insects and some other animals: males present females a tasty or valuable gift – it’s like Valentine’s Day, but every day,” said Coby Schal, Blanton J. Whitmire Distinguished Professor of Entomology at NC State and co-corresponding author of the paper. Glucose Aversion Disrupts Mating The study shows, however, that females averse to the simple sugar glucose get an unpleasant surprise when they mix their saliva with the male secretions – saliva degrades the sweet treat of complex sugars to glucose, which becomes a bitter pill that ends the courtship ritual, with the female scurrying away without mating. “We’re seeing glucose-averse female German cockroaches turning down this nuptial gift – and the chance to mate – and wanted to understand more about the mechanism behind it,” said Ayako Wada-Katsumata, principal research scholar at NC State and co-corresponding author of the paper. When successful, male cockroaches entice females with a gift of chemical secretions. As females feed on the treat, the mating process begins. Glucose-averse females will flee the scene, though, when their saliva makes the treat unpalatable. Credit: Ayako Wada-Katsumata The Role of Saliva and Sugars in Cockroach Courtship Generally, cockroaches love sugar. But some have developed an aversion to glucose; Wada-Katsumata in 2013 published a paper that showed the neural mechanism behind this aversion in German cockroaches, a behavior that perhaps has become more pronounced due to the presence of the simple sugar in roach baits placed inside homes. In a 2021 study, Wada-Katsumata and Schal showed that cockroach saliva converts complex sugars into glucose. “Male cockroach secretions have different types of sugars – in this case, maltose and maltotriose, which are usually preferred by females – as well as some fats,” Wada-Katsumata said. Maltose is relatively easy to convert to glucose, while maltotriose is more complex and takes a bit longer to break down into glucose, she said. “Cockroach saliva has a class of chemicals that breaks down sugars,” Schal said. “As females feed on their gift, maltose is rapidly converted to glucose, and glucose-averse females sense a bitter taste and stop feeding, which also ends the mating opportunity.” The cockroach mating process is interesting but likely unfamiliar to bipeds. Males approach females, raise their wings, and release chemicals via the tergal gland on their backs. Females attracted to the secretion will climb onto the male’s back and feed on the secretion. While she feeds, the male will telescope his abdomen under the female, grab her with an elongated hooked penis and move into position for mating. This courtship process takes only seconds; it is here that the rapid chemical conversion of complex sugars to simple sugars in saliva could kill the mood for glucose-averse females. If successful, though, roaches engage in a back-to-back, up to 90-minute-long mating session, with the male using a second penis to transfer a sperm package to the female.  In the study, the researchers performed various experiments to ascertain how glucose aversion affects cockroach courtship. They found that glucose-averse females more frequently interrupted feeding due to their aversion, especially when feeding from a wild-type male – one that was not averse to glucose. Glucose-averse males often had higher levels of maltotriose in their secretions, which converted less easily to glucose and therefore gave those males extra time to begin mating. The researchers also changed the quality of the male secretion, substituting fructose for the glucose and maltose secretions. Glucose-averse females enjoyed fructose and fed on it longer, resulting in more successful mating sessions. Impact on Mating Success and Evolutionary Adaptation “This study is a direct way to show that the quality of secretion affects female behavior and mating success,” Schal said. “There is a tradeoff between sexual selection and natural selection. Think of deer as an example. Male deer have horns, not for natural selection – horns actually put males in danger from predators and hunters – but for sexual selection to appeal to females and serve as useful weapons in competition with other males. Similarly, the cockroach’s tergal gland evolved for attracting females in the context of sexual selection.” “Wild-type females accept the sugary secretions. Glucose-averse females don’t accept the wild-type secretions because they easily convert to glucose. Males can change the composition of secretions – perhaps producing more maltotriose which takes longer to convert to glucose – or try to mate faster. In short, the glucose aversion trait evolved under natural selection, but under sexual selection it is causing the male to modify his sexual secretion and behavior,” Wada-Katsumata said. The 2013 study informed bait manufacturers not to use glucose in baits. The 2021 studies expand this recommendation to all sugars that contain glucose. Baits made with glucose, sucrose, maltose, and other sugars will be ignored by glucose-averse cockroaches. As more cockroaches with glucose aversion survive, that trait will be passed down in greater numbers. “We are constantly in an evolutionary battle with cockroaches,” Schal said. “Evolution can be sped up tremendously in the urban, human environment because the selection force imposed on insects, especially inside homes, is so intense.” Reference: “Rapid evolution of an adaptive taste polymorphism disrupts courtship behavior” by Ayako Wada-Katsumata, Eduardo Hatano, Samantha McPherson, Jules Silverman and Coby Schal, 12 May 2022, Communications Biology. DOI: 10.1038/s42003-022-03415-8 The study appears in Nature Communications Biology. Postdoctoral scholar Eduardo Hatano, Ph.D. student Samantha McPherson and Jules Silverman, Charles G. Wright Distinguished Emeritus Professor of Entomology, co-authored the paper. The research was supported by the National Science Foundation under grant IOS-1557864, the U.S. Department of Housing and Urban Development Healthy Homes program (NCHHU0053-19), and the Blanton J. Whitmire Endowment at NC State.

The 93-year-old Xerces blue butterfly specimen used in this study. Credit: Field Museum The Xerces blue butterfly was last seen flapping its iridescent periwinkle wings in San Francisco in the early 1940s. It’s generally accepted to be extinct, the first American insect species destroyed by urban development, but there are lingering questions about whether it was really a species to begin with, or just a sub-population of another common butterfly. In a new study in Biology Letters, researchers analyzed the DNA of a 93-year-old Xerces blue specimen in museum collections, and they found that its DNA is unique enough to merit being considered a species. The study confirms that yes, the Xerces blue really did go extinct, and that insect conservation is something we have to take seriously. “It’s interesting to reaffirm that what people have been thinking for nearly 100 years is true, that this was a species driven to extinction by human activities,” says Felix Grewe, co-director of the Field’s Grainger Bioinformatics Center and the lead author of the Biology Letters paper on the project. “There was a long-standing question as to whether the Xerces blue butterfly was truly a distinct species or just a population of a very widespread species called the silvery blue that’s found across the entire west coast of North America,” says Corrie Moreau, director of the Cornell University Insect Collections, who began work on the study as a researcher at Chicago’s Field Museum. “The widespread silvery blue species has a lot of the same traits. But we have multiple specimens in the Field Museum’s collections, and we have the Pritzker DNA lab and the Grainger Bioinformatics Center that has the capacity to sequence and analyze lots of DNA, so we decided to see if we could finally solve this question.” A collections drawer of extinct Xerces blue butterflies. Credit: Field Museum To see if the Xerces blue really was its own separate species, Moreau and her colleagues turned to pinned butterfly specimens stored in drawers in the Field’s insect collections. Using forceps, she pinched off a tiny piece of the abdomen of a butterfly collected in 1928. “It was nerve-wracking, because you want to protect as much of it as you can,” she recalls. “Taking the first steps and pulling off part of the abdomen was very stressful, but it was also kind of exhilarating to know that we might be able to address a question that has been unanswered for almost 100 years that can’t be answered any other way.” Once the piece of the butterfly’s body had been retrieved, the sample went to the Field Museum’s Pritzker DNA Laboratory, where the tissues were treated with chemicals to isolate the remaining DNA. “DNA is a very stable molecule, it can last a long time after the cells it’s stored in have died,” says Grewe. Even though DNA is a stable molecule, it still degrades over time. However, there’s DNA in every cell, and by comparing multiple threads of DNA code, scientists can piece together what the original version looked like. “It’s like if you made a bunch of identical structures out of Legos, and then dropped them. The individual structures would be broken, but if you looked at all of them together, you could figure out the shape of the original structure,” says Moreau. Study authors Felix Grewe and Corrie Moreau working in the Field Museum’s Pritzker DNA Lab. Credit: Field Museum Grewe, Moreau, and their colleagues compared the genetic sequence of the Xerces blue butterfly with the DNA of the more widespread silvery blue butterfly, and they found that the Xerces blue’s DNA was different, meaning it was a separate species. The study’s findings have broad-reaching implications. “The Xerces blue butterfly is the most iconic insect for conservation because it’s the first insect in North America we know of that humans drove to extinction. There’s an insect conservation society named after it,” says Moreau. “It’s really terrible that we drove something to extinction, but at the same time what we’re saying is, okay, everything we thought does in fact align with the DNA evidence. If we’d found that the Xerces blue wasn’t really an extinct species, it could potentially undermine conservation efforts.” DNA analysis of extinct species sometimes invites questions of bringing the species back, à la Jurassic Park, but Grewe and Moreau note in their paper that those efforts could be better spent protecting species that still exist. “Before we start putting a lot of effort into resurrection, let’s put that effort into protecting what’s there and learn from our past mistakes,” says Grewe. Moreau agrees, noting the urgent need to protect insects. “We’re in the middle of what’s being called the insect apocalypse– massive insect declines are being detected all over the world,” says Moreau. “And while not all insects are as charismatic as the Xerces blue butterfly, they have huge implications for how ecosystems function. Many insects are really at the base of what keeps many of these ecosystems healthy. They aerate the soil, which allows the plants to grow, and which then feeds the herbivores, which then feed the carnivores. Every loss of an insect has a massive ripple effect across ecosystems.” In addition to the study’s implications for conservation, Grewe says that the project showcases the importance of museum collections. “When this butterfly was collected 93 years ago, nobody was thinking about sequencing its DNA. That’s why we have to keep collecting, for researchers 100 years in the future.” Reference: “Museum genomics reveals the Xerces blue butterfly (Glaucopsyche xerces) was a distinct species driven to extinction” by Felix Grewe, Marcus R. Kronforst, Naomi E. Pierce and Corrie S. Moreau, 21 July 2021, Biology Letters. DOI: 10.1098/rsbl.2021.0123

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