Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw

ESG-compliant OEM manufacturer in Vietnam

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Taiwan foot care insole ODM development factory

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Graphene sheet OEM supplier Thailand

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.High-performance graphene insole OEM China

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Insole ODM factory in Indonesia

Just two weeks of citalopram exposure caused changes in crayfish behavior. Credit: Stefan, iNaturalist Increased foraging and reduced aggression have the potential to alter stream functioning. Pharmaceutical pollution is found in streams and rivers globally, but little is known about its effects on animals and ecosystems. A new study, published in the journal Ecosphere, investigated the effects of antidepressant pollution on crayfish. Just two weeks of citalopram exposure caused changes in crayfish behavior, with the potential to disrupt stream ecosystem processes like nutrient cycling, oxygen levels, and algal growth. Coauthor Emma Rosi, a freshwater ecologist at Cary Institute of Ecosystem Studies, says, “Animals living in streams and rivers are exposed to a chronic mix of pharmaceutical pollution as a result of wastewater contamination. Our study explored how antidepressant levels commonly found in streams impact crayfish, and how these changes reverberate through stream ecosystems.” Crayfish are a keystone species in streams, where they eat invertebrates, break down leaf litter, and cycle nutrients. They are stress-tolerant and can become abundant in urban waterways. These freshwaters are prone to receiving pharmaceutical pollution from sewer overflows, leaky septic tanks, and treated wastewater effluent that contains pharmaceuticals. Lead author Alexander Reisinger, an Assistant Professor at University of Florida, Gainesville, says, “Previous research via direct injection found that antidepressants alter serotonin and aggression in crustaceans. Our study found that exposure to low doses of citalopram — at levels currently found in urban streams as a result of pollution — is enough to alter crayfish behaviors like foraging, aggression, and shelter use.” Cary Institute’s artificial stream facility was used to test effects of citalopram on crayfish and stream ecosystems. Twenty stream habitats were created with low-nutrient groundwater and quartz rocks and red maple leaf packs that had been colonized with microbes, invertebrates, and algae. Streams were randomly selected to receive one of four treatments: no citalopram + no crayfish, citalopram + no crayfish, crayfish + no citalopram, and citalopram + crayfish. Each treatment was applied to five streams. Three male crayfish were added to each of the ‘crayfish’ streams. For two weeks, the team dosed the 10 streams receiving citalopram every other day to mimic low, persistent pharmaceutical pollution found in urban streams. Over the course of the experiment, they monitored indicators that would reveal changes in stream ecosystem functioning, such as dissolved oxygen, temperature, light penetration, and algae. At the end of the two weeks, the behavior of exposed and non-exposed crayfish was tested. To do this, the team tapped into crayfish’s keen sense of smell. They used a tank containing a shelter at one end and a divider down the middle. One side of the tank contained water that had passed by sardine gelatin; the other contained water that had passed by another male crayfish. One at a time, they placed the crayfish in the shelter, then recorded the amount of time it took for each to peek out of the shelter and emerge completely. They also recorded the amount of time spent in the sardine and crayfish signal sides of the tank. Crayfish exposed to citalopram emerged from the shelter sooner, indicating increased ‘boldness’. Exposed crayfish were also more interested in food, lingering in the food-scented area over 3x longer than the crayfish-scented area. Crayfish that were not exposed to citalopram took longer to emerge and divided their time equally between the food and crayfish areas, showing no preference. Reisinger explains, “Citalopram-exposed crayfish are more attracted to food, and less interested in other crayfish. Less time spent hiding and more time foraging could make crayfish more vulnerable to predators, meaning more get eaten. We would expect increased crayfish foraging to lead to higher rates of leaf litter decomposition and biofilm turnover, altering in-steam nutrient flows. Either of these changes could have cascading effects.” In people, ‘metabolism’ refers to a collection of chemical processes that regulate bodily functions essential to health like breathing, digestion, and temperature regulation. Stream ‘metabolism’ includes a variety of indicators like oxygen levels, light penetration, and nutrient cycling, which together shape stream health. The team used their two-week record of stream indicators to assess changes in the metabolism of each stream. They found that crayfish presence versus absence significantly affects stream metabolism. Effects of citalopram alone were not significant, but results suggest that changes in stream functioning would likely occur over time due to citalopram’s effects on crayfish behavior. Reisinger explains, “With just two weeks of citalopram exposure, we saw marked changes in crayfish behavior. Over months to years, we would expect these changes to magnify. Fewer crayfish could reduce populations of the fish that eat them like trout, bass, and catfish. Changes in algal growth or turnover would alter oxygen levels and nutrient dynamics — key aspects of stream functioning that could cause harmful imbalances in the system.” Rosi concludes, “Toxicity assessments of pharmaceuticals often focus on lethal effects, but it is clear that these drugs can affect non-target organisms without killing them and behavioral changes can have ecological consequences. More work is needed to understand how pharmaceutical pollution impacts stream life at chronic, sublethal levels, and what these changes mean for freshwater quality, ecosystem health, and foodwebs — in streams and beyond.” Reference: “Exposure to a common antidepressant alters crayfish behavior and has potential subsequent ecosystem impacts” by Alexander J. Reisinger, Lindsey S. Reisinger, Erinn K. Richmond and Emma J. Rosi15 June 2021, Ecosphere. DOI: 10.1002/ecs2.3527

Humbertium covidum, an invasive hammerhead worm found in Italy. Credit: Pierre Gros Two new species of potentially invasive hammerhead flatworms from Europe (France and Italy) and Africa (Mayotte) “Alien” species of predatory hammerhead worms – including a spectacularly iridescent green-blue specimen – identified in Europe and Africa. One of the consequences of globalization is the inadvertent spread of invasive plant and animal species. Land flatworms have invaded the entire world, principally via the plant trade. More than ten species are now widespread, such as Obama nungara (originally from Argentina), Platydemus manokwari (from New Guinea) and Bipalium kewense (from Southeast Asia). Diversibipalium mayottensis, an invasive species of hammerhead worm found in Mayotte. Credit: Laurent Charles An international team led by Professor Jean-Lou Justine from ISYEB (Muséum National d’Histoire Naturelle, Paris, France) reports the description of two new species of hammerhead flatworms. This is the first study of these species, reported in an article published in the Open Access journal PeerJ. Land flatworms are predators of soil animals, including earthworms, slugs, and snails. They are a threat to soil biodiversity and ecology when they are introduced in a new environment. Hammerhead flatworms are specialized members of this family showing a broadened head. A number of species of hammerhead flatworms have been described by scientists, not from specimens from their land of origin, but from specimens obtained from the countries already invaded. This is the case, for instance, for the two species found in the USA, Bipalium pennsylvanicum and Bipalium adventitium, which originate from Asia but were not reported from any Asian country. The two new species described in this new paper follow a similar pattern. The research highlights the problem of alien species, and their potential to become invasive. They are one of the major threats to biodiversity, with considerable cost impacts on the economy. A full range of techniques were used, including citizen science, field expeditions, macro photography, classical morphology, and new generation sequencing in molecular biology. Hammerhead flatworms include some “giants” among land flatworms, with one species reaching one meter in length. However, the new species described here are small, possibly explaining why they escaped the attention of researchers before. The first new species was named Humbertium covidum in reference to the work being completed during lockdowns caused by the global pandemic and “as homage to the victims of COVID-19,” write the authors. It was found in two gardens in the Pyrénées-Atlantiques (France) and also in Veneto (Italy). It is small (30 mm) and looks uniformly metallic black, an unusual color among hammerhead flatworms. Through genetic analyses of its intestinal contents, the researchers found that these flatworms consume small snails. The species’ origin is probably Asia, and it is potentially invasive. The second new species was named Diversibipalium mayottensis and was only found in Mayotte (a French island in the Mozambique Channel, Indian Ocean). The species is small (30 mm) and exhibits a spectacular green-blue iridescence over brown ground color. Genetic analyses, including mitogenomes, showed that this species was the sister-group of all other hammerhead flatworms (subfamily Bipaliinae) and is thus of special interest for understanding the evolution of these worms. Its origin could be Madagascar, from where it would have been inadvertently brought to Mayotte by people at some time in the past. Jean-Lou Justine said “Due to the pandemic, during the lockdowns most of us were home, with our laboratory closed. No field expeditions were possible. I convinced my colleagues to gather all the information we had about these flatworms, do the computer analyses, and finally write this very long paper. We decided to name one of the species “covidum,” paying homage to the victims of the pandemic.” In addition to classical anatomical and morphological descriptions, the researchers used the characters of complete mitogenomes to characterize the new species. Mitochondrial genomes (or mitogenomes) with about 15,000 base pairs, provide a significant amount of information, especially details about their genes. The researchers, who had previously studied the mitogenomes in four species of land flatworms, describe here the complete mitogenomes of five species of hammerhead flatworms. Complete mitogenomes and other sequences generally used for phylogeny, such as those of Small and Large Subunit Ribosomal RNA (SSU and LSU), allowed the research team to propose the first molecular study of relationships within the hammerhead flatworms (subfamily Bipaliinae). Reference: “Hammerhead flatworms (Platyhelminthes, Geoplanidae, Bipaliinae): mitochondrial genomes and description of two new species from France, Italy, and Mayotte” by Jean-Lou Justine​, Romain Gastineau, Pierre Gros, Delphine Gey, Enrico Ruzzier, Laurent Charles and Leigh Winsor, 1 February 2022, Peerj. DOI: 10.7717/peerj.12725

The researchers found preserved bone cells in the carapace, which exhibited structures like the nucleus of a cell, where DNA traces were found. Credit: Dr. Edwin Cadena, Universidad del Rosario and STRI There are seven existing species of sea turtles, with the genus Lepidochelys comprising two of them: the olive ridley and the Kemp’s ridley. Despite being among the most common sea turtles in much of the Caribbean Sea and elsewhere, these species have a largely mysterious history and evolutionary background. Recently, the discovery of a turtle shell fossil on the Caribbean coast of Panama has shed light on their ancient past, representing the oldest fossil evidence of these turtles to date. A Glimpse into the Miocene Epoch The discovery of the fossil in the Chagres Formation indicates that this turtle lived approximately 6 million years ago in Panama in the upper Miocene Epoch, a time when the world was getting cooler and drier, with ice accumulating at the poles, sea levels falling, and reduced rainfall. The remains were analyzed by a team of paleontologists led by Dr. Edwin Cadena of the Universidad del Rosario in Bogotá, Colombia, who is also a research associate at the Smithsonian Tropical Research Institute in Panama. Fossil remains of a turtle shell from 6 million years ago were found in Piña Beach, on the Caribbean coast of Panama. Credit: Carlos De Gracia, University of Vienna and STRI In addition to finding the oldest record of Lepidochelys turtles, the researchers discovered something unexpected in the fossil bones of this turtle: traces of DNA. After detecting preserved bone cells (osteocytes) with nucleus-like structures, they used a solution called DAPI to test for the presence of the genetic material. “Within the entire vertebrate fossil record on the planet, this had only been previously reported in two dinosaur fossils, including one of Tyrannosaurus rex,” Dr. Cadena pointed out, referring to the ancient DNA. Implications for Molecular Paleontology This discovery gives the fossil vertebrates preserved on the Caribbean coast of Panama enormous importance not only for understanding biodiversity at the time of the emergence of the Isthmus of Panama, which divided the Caribbean from the Pacific and joined North and South America, but also for understanding the preservation of soft tissues and possible original living matter such as proteins and DNA, essential components of an emerging field known as Molecular Paleontology. “The Caribbean fossils from Panama that we have managed to rescue over the years are helping to rewrite the history of marine vertebrates of the Isthmus,” said Carlos De Gracia, co-author of the study and a doctoral fellow affiliated with STRI who is funded by Panama’s Office for Science and Technology (SENACYT). Reference: “An Upper Miocene marine turtle from Panama that preserves osteocytes with potential DNA” by Edwin-Alberto Cadena, Carlos De Gracia and Diego A. Combita-Romero, 23 November 2023, Journal of Vertebrate Paleontology. DOI: 10.1080/02724634.2023.2254356 This research resulted from cooperation between the Smithsonian Tropical Research Institute and the Faculty of Natural Sciences of the Universidad del Rosario.  The study was funded by the Universidad del Rosario and the National Secretary of Science and Technology of Panama.

DVDV1551RTWW78V