Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw

Taiwan graphene sports insole ODM

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Indonesia high-end foam product OEM/ODM

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Arch support insole OEM from Indonesia

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Taiwan sustainable material ODM production base

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Cushion insole OEM manufacturing facility Taiwan

Research shows DPANN archaea selectively consume host lipids, prompting significant changes in host metabolism and membrane resilience and potentially affecting environmental adaptability. Credit: SciTechDaily Microbiologists from NIOZ, the Royal Netherlands Institute for Sea Research, have discovered that certain parasitic microbes, specifically a group known as DPANN archaea, not only feed on their hosts but also change the host’s metabolism and biology. Their study reveals that these archaea selectively consume certain lipids from their hosts, potentially causing the hosts to alter their metabolic processes. The research team, which includes Su Ding, Joshua Hamm, Nicole Bale, Jaap Damsté, and Anja Spang, published these findings in a recent Nature Communications article. Understanding Archaea Archaea are a distinct group of single-celled organisms that, like bacteria, do not have a nucleus with DNA, or other organelles within their cells. The study focuses on DPANN archaea, which are characterized by their tiny cell size and limited genetic material. These archaea are dependent on other microbes for survival, attaching to them and extracting lipids to construct their own cellular membranes. Electron microscopy showing the parasitic Ca. Nha. antarcticus: the small circular shape, attached to its host, Hrr. lacusprofundi. Credit: Joshua N Hamm Selective Feeding Contrary to the previous belief that these parasitic archaea indiscriminately consume any lipids from their hosts for their membranes, recent findings by Ding and Hamm indicate a more selective behavior. Specifically, the parasitic archaeon Candidatus Nanohaloarchaeum antarcticus selectively incorporates only certain lipids from its host, Halorubrum lacusprofundi. Hamm summarizes, “In other words: Ca. N. antarcticus is a picky eater.” Archaea, Bacteria and Higher Organisms Archaea are single celled organisms that were long believed to be a specific group of bacteria. Similar to bacteria, they do not have a nucleus with dna, or other organelles within their cells. As of the 1970’s, however, microbiologists no longer consider archaea bacteria, but classify them as a separate domain in all life forms. So, now we have archaea, bacteria, and eukaryotes, the latter including all animals and plants, that have a nucleus with genetic material in their cells. Host Adaptations to Parasitic Activity By analyzing the lipids of the hosts both with and without parasites, Ding and Hamm were able to show that hosts adapt to the presence of parasites by altering their membranes. This involves changing both the types and quantities of lipids used, as well as modifying the lipids to change their behavior, leading to increased metabolism and a more resilient membrane that is tougher for the parasite to penetrate. According to Hamm, this could have serious consequences for the host.“If the membrane of the host changes, this could have an impact on how these hosts can respond to environmental changes, in for example temperature or acidity,” he explains. Another example of the parasitic Ca. Nha. antarcticus attached to its host, Hrr. lacusprofundi. Credit: Joshua N Hamm Revolutionary Analytical Techniques Another groundbreaking aspect of this research was the development of a new analytical technique by Su Ding at NIOZ. Previously, lipid analysis required prior knowledge of the lipid groups to be targeted. Ding’s new technique allows for the examination of all lipids simultaneously, including unknown types, facilitating the discovery of changes in lipid composition. “We probably wouldn’t have been able to see the changes in the lipids if we had used a classical approach, but the new approach made it straightforward,” says Hamm. Implications for Microbial Ecology These findings offer profound insights into microbial interactions and ecology. “Not only does it shed a first light on the interactions between different archaea; it gives a totally new insight into the fundamentals of microbial ecology,” Hamm remarks. He emphasizes the importance of future research to determine how these interactions might affect the stability of microbial communities under changing environmental conditions. Reference: “Selective lipid recruitment by an archaeal DPANN symbiont from its host” by Su Ding, Joshua N. Hamm, Nicole J. Bale, Jaap S. Sinninghe Damsté and Anja Spang, 22 April 2024, Nature Communications. DOI: 10.1038/s41467-024-47750-2

An elephant, Loxodonta africana, throws dirt into the air in the tall grass of the savanna. Credit: Jeffrey T. Kerby A new meta-analysis across six continents establishes that large wild herbivores affect ecosystems in numerous important ways, from soils to vegetation to smaller animals, and promote ecosystem variability. For millions of years, a variety of large herbivores, or megafauna, influenced terrestrial ecosystems. Among many others, these included elephants in Europe, giant wombats in Australia, and ground sloths in South America. However, these animals experienced a wave of extinctions coinciding with the worldwide expansion of humans, leading to dramatic but still not fully understood changes in ecosystems. Even the survivors of these extinctions strongly declined, and many are currently threatened with extinction. While there are many case studies as well as theories about the effects of large animals, formal attempts to quantitatively synthesize their effects and establish generality have been lacking. A new study, conducted by an international team led by researchers from Aarhus University and the University of Göttingen, published in Nature Ecology & Evolution, has gathered numerous individual case studies and analyzed the findings. They show that large animals have a variety of generalizable impacts – impacts that are likely missing from most of today’s ecosystems. The impact of large animals on ecosystems Among the identified general impacts of large wild herbivores are shifts in soil and plant nutrients the promotion of open and semi-open vegetation the regulation of the population of smaller animals Moreover, one of the key findings of the studies is that megafauna promote ecosystem diversity by increasing the structural variability in the vegetation. “The positive impact on variability in vegetation structure is particularly noteworthy, given that environmental heterogeneity is known as a universal driver of biodiversity. While our study mostly looked at the impact of megafauna on small scales, our findings suggest that they promote biodiversity even on the landscape level,” says PhD student at Aarhus University Jonas Trepel, who led the study. Large herbivores change vegetation structure by consuming biomass, breaking woody plants, and trampling smaller plants – impacts that are hypothesized to depend on the animal’s body size. Given that the analyzed dataset spanned two magnitudes of body size (45-4500 kg), the researchers were able to test specifically how this important trait shapes the impact of large animals. They found, for example, that megafauna communities which include larger herbivores tend to have positive effects on local plant diversity, while communities composed of smaller species (e.g. <100 kg) tend to decrease local plant diversity. “Large herbivores can eat lower-quality food such as branches and stems, which may result in proportionally greater impacts on dominant plant species and thus give less competitive plants better odds in their struggle for sunlight and space,” explains Erick Lundgren, one of the senior authors of the study. Assistant professor Elizabeth le Roux, who is also one of the senior authors, adds: “These findings support the expectation that many small herbivores cannot fully compensate for the loss of a few large ones.” The benefits of a meta-analysis This study is a so-called meta-analysis. This means that the researchers have analyzed data from all available studies on the subject in order to find general patterns. Meta-analyses are especially powerful in their conclusions because they draw on big data pools and make it possible to draw conclusions that go beyond a local context. While many recent ecological studies have shown or hypothesized the importance of large animals in ecosystems, according to senior author Jens-Christian Svenning, the meta-analytical study is an important step forward by synthesizing direct experimental and semi-experimental evidence from across the globe to assess the generality of these effects quantitatively. “This global meta-analysis shows that large herbivores have important general effects on ecosystems and their biodiversity,” explains professor Jens-Christian Svenning, continuing: “Importantly, our analysis shows that these effects cut across a broad range of ecologically important phenomena, from soil conditions to vegetation structure to plant and animal species composition, affecting not only their general state but also their variation across landscapes.” Jens-Christian Svenning is the director of Center for Ecological Dynamics in a Novel Biosphere (ECONOVO), a Danish National Research Foundation center of excellence at Aarhus University. How did the researchers get these results? A key aspect of the 297 studies, including 5,990 individual data points, is that the researchers compare adjacent areas with clear differences in the megafauna community (i.e. megafauna present or absent) due to known reasons. The vast majority of studies in the data set are so-called exclosure studies, in which some parts of a field site are fenced up to prevent large animals from entering. By comparing different plots inside and outside of the fences, researchers are then able to assess in which ways megafauna impact the ecosystem. Importance of ecosystem biodiversity in responding to global change The identified general importance of large herbivores for ecosystem functioning implies that important functions are missing due to the loss of wild megafauna. This may affect the approach to nature conservation and ecosystem restoration. “The majority of today’s protected areas are missing large animals – and thus also an important range of functions. So even areas we consider to be pristine ecosystems are probably not as natural as we may think. Reintroducing large animals could be a key avenue to make these areas a bit more dynamic and used to disturbances,” says Jonas Trepel and continues: “By increasing the structural variability in an ecosystem, large animals may provide refuges, for example during extreme weather events, but also open up more available niches for other species. This could prevent one or a few species from dominating and allows species with similar ecological attributes to coexist – which in turn would make the ecosystem more resilient. Ultimately, that may help them to deal with the consequences of global change.” Given the important functions that large animals have on ecosystems and their biodiversity, the researchers conclude that it is crucial to not just protect the few remaining megafauna species, but also to reestablish megafauna populations as part of restoration efforts to achieve positive outcomes for Earth’s biosphere, not least under the increasingly unprecedented global environmental conditions. Reference: “Meta-analysis shows that wild large herbivores shape ecosystem properties and promote spatial heterogeneity” by Jonas Trepel, Elizabeth le Roux, Andrew J. Abraham, Robert Buitenwerf, Johannes Kamp, Jeppe A. Kristensen, Melanie Tietje, Erick J. Lundgren and Jens-Christian Svenning, 9 February 2024, Nature Ecology & Evolution. DOI: 10.1038/s41559-024-02327-6

The illustration shows the new function of blood monocytes, namely their ability to proliferate in tissues before differentiating into macrophages, immune cells that play important roles in maintaining body homeostasis and health. Credit: Adeline Deward – Illumine A recent study led by scientists from the University of Liège indicates a heightened role of cell proliferation in the functioning of our immune system. Cell division, or proliferation, is crucial for life, facilitating the evolution of complex organisms from a single cell and the renewal of expended cells from a handful of “stem” cells that multiply and specialize. In the context of cancer, however, this cell proliferation spirals out of control and becomes chaotic. A team of researchers at the University of Liège’s GIGA Institute has uncovered that specific blood immune cells known as monocytes in a healthy person also possess the capacity to proliferate. Their purpose is to replenish tissue macrophages, which are vital for our bodies to function correctly. These findings were recently published in the journal Nature Immunology. Monocyte Proliferation The formation of complex multicellular organisms, which human beings belong to, requires the generation of billions of cells from a limited number of progenitor cells that have first proliferated and then acquire particular morphologies and functions while assembling into tissues and organs. Our current knowledge indicates that most of the cells that constitute a living organism arise from so-called “stem” cells, which have been divided by a process called mitosis in order to give rise to a greater number of cells. These cells then stop proliferating to specialize, differentiate and form muscles, the brain, bones, immune cells, and more. When proliferation is no longer properly regulated, this can lead to the development of various diseases, among which cancers represent the most striking example. In a study published in Nature Immunology, Professor Thomas Marichal (Professor at ULiège, Welbio investigator at the WEL Research Institute) and his team from the GIGA Institute at ULiège discovered that this ability to proliferate is not merely restricted to stem cells, but is also an as-yet-unknown function of blood immune cells, the monocytes. Indeed, blood monocytes, previously considered as differentiated cells, are capable of proliferating and generating a pool of monocytes in the tissues in order to give rise to macrophages, which are important immune cells that protect us against microbes and support the proper functioning of our organs. “This is a major fundamental discovery, which changes our conception of the involvement of cell proliferation in the constitution and maintenance of our immune system,” explains Thomas Marichal, director of the study. “Our finding also suggests that the information that can be drawn from an enumeration of blood monocytes, classically carried out during a blood test, would reflect only little of what is happening at the level of the tissues, during ‘infection or inflammation, for example, since monocytes can proliferate when they enter tissues.” Controlled Proliferation for Tissue Renewal He also adds: “Fortunately, this proliferation is extremely well controlled and does not lead to a tumoral process. It has only one goal: to allow, as effectively as possible, the replacement of immune cells that populate our tissues: the macrophages.” This discovery, funded by the WEL Research Institute (WELRI – Welbio) and by the European Research Council was possible thanks to the development of new tools and the use of innovative technologies. “This study is a great example of how technological advances can drive breakthrough scientific discoveries. It would have been extremely difficult, if not impossible, to study with such a resolution this population of proliferating monocytes only 10 years ago. This required the use of state-of-the-art equipment recently acquired at the GIGA Institute, the generation of complex genomic data and very sophisticated bioinformatics analyses” explains Domien Vanneste, funded by a doctoral grant from the FNRS and first author of the study. This study paves the way for future investigations that will evaluate the possibility of manipulating or controlling monocyte proliferation for therapeutic purposes, for the benefit of enhanced health. Reference: “MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation” by Domien Vanneste, Qiang Bai, Shakir Hasan, Wen Peng, Dimitri Pirottin, Joey Schyns, Pauline Maréchal, Cecilia Ruscitti, Margot Meunier, Zhaoyuan Liu, Céline Legrand, Laurence Fievez, Florent Ginhoux, Coraline Radermecker, Fabrice Bureau and Thomas Marichal, 16 March 2023, Nature Immunology. DOI: 10.1038/s41590-023-01468-3 The study was funded by the funded by the WEL Research Institute (WELRI – Welbio) and by the European Research Council.

DVDV1551RTWW78V