Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw

Thailand anti-odor insole OEM service

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Taiwan custom product OEM/ODM services

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Innovative insole ODM solutions in Vietnam

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Graphene insole manufacturer in Taiwan

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.ODM service for ergonomic pillows Thailand

The cartilage of the skate is stained with Alcian blue, the bones with Alizarin red. One of the few places in the world that collects Leucoraja erinacea and breeds it for research, including for the present study, is the Marine Resources Center at the Marine Biology Laboratory in Woods Hole. Credit: David Gold Lynn Kee and Meghan Morrissey, MBL Embryology Course Researchers have discovered that little skate’s unique cape-like fins evolved through changes in the non-coding regions of its genome and the three-dimensional structures called “topologically associated domains” (TADs). This breakthrough highlights the importance of 3D genomic structures in driving evolutionary change. The little skate’s dance on the ocean floor is graceful: its massive frontal fins undulate as it skims beneath a layer of sand. With its mottled sand-colored camouflage, the animal is easy to miss. Scientists at Max Delbrück Center in Berlin, the Andalusian Center for Developmental Biology (CABD) in Seville and other labs in the United States have discovered how the skate evolved these cape-like fins by peering into their DNA. They found that the key to the evolution of the skate fins lies not in the coding regions of its genome, but rather in the non-coding bits and the three-dimensional complexes that it folds into. These 3D structures are called “topologically associated domains” (TADs). The international team describes in the journal Nature that genomic changes that alter TADs can drive evolution. Until recently, genome evolution was mostly focused on studying variation at the DNA sequence level, but not in 3D genomic structures. “This is a new way of thinking about how genomes evolve,” says Dr. Darío Lupiáñez, geneticist at the Max Delbrück Center and one of the lead authors of the study. “Although we found that unique gene-expression patterns establish exceptionally wide skate fins a while ago, the underlying regulatory changes in the genome have previously remained unknown,” says co-author Dr. Tetsuya Nakamura, developmental biologist at Rutgers University. Living embryo of the little skate sitting atop its yolk at approximately ten weeks. Credit: Mary Colasanto and Emily Mis, MBL Embryology Course More than 450 million years ago, the genome of a primitive fish — the ancestor of all vertebrate animals — duplicated twice. The expansion in genetic material drove the rapid evolution of more than 60,000 vertebrates, including humans. One of our most distant vertebrate relatives are little skates (Leucoraja erinacea), which belong to a lineage of cartilaginous fishes that includes sharks and rays. These distant cousins are ideal organisms to learn about the evolution of traits that made us human, such as paired appendages. “Skates are cartilaginous fishes called Chondrichthyans. They are considered more similar to ancestral vertebrates,” says Dr. Christina Paliou, a developmental biologist at the CABD and one of the first authors. “We can compare the characteristics of skates with other species and determine what is novel and what is ancestral.” An Exciting Time in Evolutionary Genomics In 2017, the late Dr. José Luis Gómez-Skarmeta from the CABD, a founding figure in evolutionary genomics, brought together scientists from around the world to study skate evolution: laboratories with expertise in genome evolution such as the Ferdinand Marlétaz lab at University College London and Daniel Rokhsar lab at the University of California-Berkeley, in skate biology such as the Neil Shubin lab at University of Chicago, where Tetsuya Nakamura was then located (now at Rutgers) and in 3D gene regulation such as the Juan Tena at CABD, Darío Lupiáñez and Gómez-Skarmeta labs, as well as other collaborators. Gómez-Skarmeta was interested in learning how genomes evolve structurally and functionally to promote the appearance of new traits. “To a great extent, evolution is the history of changing the regulation of gene expression during development,” he said in 2018. It was an exciting time for evolutionary genomics. Genome sequencing technologies had significantly improved and scientists could gain novel insights into how DNA, which stretches a couple of meters end-to-end, is folded into a 0.002-inch-diameter cell nucleus. “The packaging of DNA in the nucleus is far from random,” says Lupiáñez. The DNA folds into 3D structures called TADs, which contain genes and their regulatory sequences. These 3D structures ensure that the appropriate genes are switched on and off at the right time, in the right cells. Darío Lupiáñez in the lab. Credit: David Ausserhofer, Max Delbrück Center Dr. Rafael Acemel, a geneticist at the Max Delbrück Center and one of the first authors, performed experiments using the Hi-C technology, to elucidate the 3D structure of the TADs. But interpreting the results was challenging at first as the scientists needed the complete skate genome as a reference point. “At the time, the reference consisted of thousands of small unordered pieces of DNA sequence, so that did not help,” Acamel says. To overcome this difficulty, the scientists used long-read sequencing technology, together with Hi-C data, to assemble the pieces of the DNA like a puzzle and assign the unordered sequences to skate chromosomes. With the new reference, assembling the 3D structure of the TADs using Hi-C became trivial. They compared this improved skate genome with genomes of the closest relatives, sharks, to identify any TADs altered during skate evolution. These altered TADs included genes of the Wnt/PCP pathway, which is important for the development of fins. There was also a skate-specific variation in a non-coding sequence near the Hox genes, which also regulate fin development. “This specific sequence can activate several Hox genes in the front part of the fins, which does not happen in other fish or four-legged animals,” says Paliou. Subsequently, the scientists performed functional experiments that confirmed these molecular changes helped the skates evolve their unique fins. TADs Drive Evolution Earlier research has shown that changes in TADs can affect the expression of genes and cause diseases in humans. In this study, scientists show a role for TADs in driving evolution that has been previously noted for moles, too. After the primitive fish ancestor duplicated its genome, many unused and redundant parts were subsequently lost. “It was not only the genes that disappeared, but also the associated regulatory elements and the TADs they are contained in,” Lupiáñez says. “I think it’s an exciting finding as it suggests that the 3D structure of the genome has an influence on its evolution.” TADs are important for gene regulation, 40 percent of them are conserved in all vertebrates, Acemel says. “However, 60 percent of TADs have evolved in some way or another. What were the consequences of these changes for species evolution? I think that we are just scratching the surface of this exciting phenomenon,” Acemel says. This mechanism of evolution constrained by TADs could be prevalent in nature. “We suspect that these mechanisms might explain many other interesting phenotypes that we observe in nature,” Lupiáñez says. “By adding these new layers of gene expression, gene regulation, and 3D chromatin organization, the field of evolutionary genomics is entering into a new era of discovery.” Reference: “The little skate genome and the evolutionary emergence of wing-like fin appendages” by Ferdinand Marlétaz, Elisa de la Calle-Mustienes, Rafael D. Acemel, Christina Paliou, Silvia Naranjo, Pedro Manuel Martínez-García, Ildefonso Cases, Victoria A. Sleight, Christine Hirschberger, Marina Marcet-Houben, Dina Navon, Ali Andrescavage, Ksenia Skvortsova, Paul Edward Duckett, Álvaro González-Rajal, Ozren Bogdanovic, Johan H. Gibcus, Liyan Yang, Lourdes Gallardo-Fuentes, Ismael Sospedra, Javier Lopez-Rios, Fabrice Darbellay, Axel Visel, Job Dekker, Neil Shubin, Toni Gabaldón, Tetsuya Nakamura, Juan J. Tena, Darío G. Lupiáñez, Daniel S. Rokhsar and José Luis Gómez-Skarmeta, 12 April 2023, Nature. DOI: 10.1038/s41586-023-05868-1

Appearances can be deceptive: the appearance of leaf insects does not necessarily reflect their species affiliation. While Pulchriphyllium anangu (A) is a new, distinct species from India, the other two individuals (B and C) both belong to the newly described Philippine species Phyllium ortizi, despite their external differences. Credit: Vishwanath Gowda (A), Maxime Ortiz (B and C) An international team of scientists, including researchers from the University of Göttingen, has unveiled seven new species of leaf insects, commonly known as walking leaves. A team of international researchers, including experts from the University of Göttingen, has identified seven new species of leaf insects, also known as “walking leaves.” These insects are part of the stick and leaf insect order and are known for their unusual appearance: they look confusingly similar to parts of plants such as twigs, bark, or – in the case of leaf insects – leaves. Their advanced camouflage not only serves as a defense mechanism against predators but also poses a challenge for scientific study. Through genetic analysis, the scientists were able to uncover “cryptic species,” which look identical externally but are genetically distinct. This research has significant implications not only for the systematic classification of leaf insects but also for the conservation of their biodiversity. The findings were recently published journal ZooKeys. The Complexity of Taxonomy in Leaf Insects Taxonomy – meaning the naming, description, and classification of species – is difficult in the case of leaf insects: individuals of different species can be difficult to tell apart, yet there can be huge variations within a species. “Individuals of different species are often counted as belonging to the same species based on their appearance. We were only able to identify some of the new species by their genetic characteristics,” explains the Project Lead, Dr Sarah Bank-Aubin, Göttingen University’s Animal Evolution and Biodiversity Department. Some individual insects from India were previously thought to belong to a species that is widespread in Southeast Asia. But now the researchers have found out that they are a completely new species of leaf insects. Bank-Aubin emphasizes: “The finding is important for species conservation: if all the individuals die out in India, it is not just a group within a species that is reduced, as was previously thought. In fact, a whole distinct species is being wiped out. This means that the Indian species is particularly important to protect.” Other newly discovered species come from Vietnam, Borneo, Java, and the Philippines. The researchers from Göttingen University worked with leaf insect expert Royce Cumming, City University New York. This research collaboration has led to the identification of over twenty new species. The Unique Evolution of Stick and Leaf Insects Dr Sven Bradler, who has been researching the evolution of stick and leaf insects at the University of Göttingen for more than 20 years, explains: “There are around 3,500 known species of stick and leaf insects and there are currently just over 100 described species of leaf insect. Although they only make up a small fraction of this diverse family of insects, their spectacular and unexpected appearance makes them unique.” Reference: “On seven undescribed leaf insect species revealed within the recent “Tree of Leaves” (Phasmatodea, Phylliidae)” by Royce T. Cumming, Stéphane Le Tirant, Jackson B. Linde, Megan E. Solan, Evelyn Marie Foley, Norman Enrico C. Eulin, Ramon Lavado, Michael F. Whiting, Sven Bradler and Sarah Bank, 3 August 2023, ZooKeys. DOI: 10.3897/zookeys.1173.104413

Novel methods for culturing previously “unculturable” bacteria. Credit: Molina-Menor, Gimeno-Valero, Peretó and Porcar The culture-dependent study allowed to isolate a surprisingly large number of diverse and previously unreported bacterial strains from the Tabernas Desert. Microorganisms are the most abundant and diverse form of life on Earth. However, the vast majority of them remain unknown. Indeed, only a small fraction of the microorganisms of our planet can be cultured under traditional conditions, leaving a world of unculturable organisms out of our scope. This is especially true for bacteria thriving under extreme conditions as the harsh conditions are hardly reproducible in a lab. While some microbial studies have been performed in the Sahara, the Atacama, and the Gibson desert, European arid lands remain poorly studied. To finally explore the microbial community of some European deserts, researchers from the University of Valencia and the Darwin Bioprospecting Excellence, here studied the bacterial diversity of the semi-arid Tabernas Desert. To this aim, the team developed new bacterial culture approaches. The semi-arid Tabernas Desert in the province of Almería, Spain. Credit: Molina-Menor, Gimeno-Valero, Peretó and Porcar “Culturomics of the Tabernas desert was the ideal crossroad between a rare, poorly studied environment, and the application of simple, yet powerful culturing techniques including long incubation times, diluted media, and careful colony picking,” says Dr. Manuel Porcar, group leader at the University of Valencia, president of Darwin Bioprospecting Excellence, and last author of the study. Simple Strategies for Culturing the Unculturable The researchers experimented with different culture methods to find permissive conditions for some unculturable species. Their strategy lay in combining different media, using serial dilutions of the nutrients (up to a hundred times), and extending incubation time (up to a month). In total, 254 bacterial strains were isolated. Most of the species isolated from the concentrated media were previously described as soil inhabitants or species isolated from other deserts. However, 60% of the strains isolated from the highly diluted media are non-identified and possibly new bacteria species. Besides, playing on incubation times also allowed, after a month, to isolate some oligotrophic strains (slow-growing bacteria living under low nutrient conditions) otherwise difficult to grow under lab conditions. The semi-arid Tabernas Desert in the province of Almería, Spain. Credit: Molina-Menor, Gimeno-Valero, Peretó and Porcar The Bigger Picture: From Ecology to Biotechnology Altogether, this study highlights the potential of simple strategies to obtain higher microbial diversity from natural samples, especially if taken from extreme environments. But the unexploited bacterial biodiversity of the Tabernas Desert could have impacts well beyond ecology and bacteriology: “We are currently characterizing several of the unidentified bacteria, three of them being new Kineococcus species. I am certain that some bacterial strains produce biotechnologically relevant products. It is just a matter of carrying out the right screening,” says Porcar. Reference: “High Culturable Bacterial Diversity From a European Desert: The Tabernas Desert” by Esther Molina-Menor, Helena Gimeno-Valero, Javier Pascual2, Juli Peretó and Manuel Porcar, 8 January 2021, Frontiers in Microbiology. DOI: 10.3389/fmicb.2020.583120

DVDV1551RTWW78V