Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Memory foam pillow OEM factory China

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.ODM pillow for sleep brands Vietnam

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Taiwan neck support pillow OEM

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Taiwan graphene sports insole ODM factory

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Indonesia insole ODM design and production

Researchers have documented painted lady butterflies’ transoceanic migration of over 4200 km, linking Europe and South America through genetic and environmental evidence. This study highlights the significant ecological implications of such long-distance migrations, especially under changing global climatic conditions. Scientists at CSIC have documented a 4200 km oceanic flight from West Africa to French Guiana in South America. An international team of researchers, led by the Spanish National Research Council (CSIC), has documented a transoceanic flight of more than 4,200 km (2,600 miles) by painted lady butterflies (Vanessa cardui), setting a record for an insect. The study, published in the journal Nature Communications, involved researchers from the Botanical Institute of Barcelona (IBB), a joint center of the CSIC and the Natural Sciences Museum of Barcelona, as well as from the W. Szafer Botanical Institute (Poland), the University of Ottawa (Canada), the Institute of Evolutionary Biology (IBE, CSIC-Universitat Pompeu Fabra), and Harvard University (USA). In October 2013, Gerard Talavera, a CSIC researcher at the Botanical Institute of Barcelona, identified several painted lady butterflies on the Atlantic beaches of French Guiana. These observations were completely unusual, as this species is not found in South America. Where did they come from? A Sum of Novel Techniques Solves the Enigma A multidisciplinary approach has deciphered the route and origin of these butterflies. The initial hypotheses were that they could have originated in North America, where the nearest populations are found, or that they traveled from Africa or Europe. By analyzing wind trajectories, researchers observed a sustained directional pattern from West Africa, opening the possibility that they had crossed the Atlantic. By studying the genetic diversity of the butterflies, which required collecting samples from populations on all continents, they determined that the specimens observed in South America were related to populations in Europe and Africa, ruling out the possibility of a North American origin. The researchers also analyzed the pollen DNA that the butterflies carried on their bodies, and identified two plant species found only in tropical Africa, thus proving that the butterflies visited flowers in that region. A painted lady Butterfly. Credit: Gerard Talavera Lastly, the scientists analyzed the stable isotopes of hydrogen and strontium from the butterflies’ wings. The wings preserve isotopic signatures unique to the place where they were raised in their larval stage, allowing inference of their natal origin. With this data, they determined that their origin was most likely in western European countries such as France, Ireland, the United Kingdom, or Portugal. “The painted lady butterflies reached South America from West Africa, flying at least 4200 km (2600 miles) over the Atlantic. But their journey could have been even longer, starting in Europe and passing through three continents, implying a migration of 7000 km (4350 miles) or more. This is an extraordinary feat for such a small insect,” explains Clément Bataille, a professor at the University of Ottawa in Canada and co-author of the study. “We tend to see butterflies as a symbol of the fragility of beauty, but science shows us that they can perform incredible feats. There is still much to discover about their capabilities,” says Roger Vila, a researcher at the Institute of Evolutionary Biology (IBE, CSIC-Universitat Pompeu Fabra) and co-author of the study. With the Help of the Wind The researchers have modeled the energetic cost of the journey and calculated that the flight across the ocean, without any stop, lasted between 5 and 8 days. This was energetically possible because it was facilitated by favourable wind currents. “The butterflies could only have completed this flight using a strategy alternating between minimal effort to avoid falling into the sea, facilitated by ascending winds, and active flight, which requires more energy consumption. We estimate that without wind, the butterflies could have flown a maximum of 780 km (480 miles) before exhausting all their fat and thus their energy,” comments Eric Toro-Delgado, one of the authors of the paper. The researchers highlight the importance of the Saharan air layer as a potential aerial highway for dispersion. These wind currents, which are prevalent throughout the year, transport large amounts of Saharan dust from Africa to America and participate in important biogeochemical cycles. However, the biological components transported, including living organisms, should be studied in depth. The Potential Impact of Migration in the Context of Global Change This finding suggests that natural aerial corridors connecting continents may exist, facilitating the dispersal of species on a much larger scale than previously imagined. “This discovery opens new perspectives on the capabilities of insects to disperse over long distances, even across seas and oceans. It is possible that we are underestimating the frequency and impact of these movements on our ecosystems,’ comments Gerard Talavera, leader of the study. “Throughout history, migratory phenomena have been important in defining the distributions of species that we observe today,” he adds. The researchers emphasize that with global warming and changing climatic patterns, it is likely that we will observe greater alterations and even an increase in these long-distance dispersal events, which could have significant implications for biodiversity and ecosystems worldwide. “It is essential to promote systematic monitoring routines for dispersing insects, which could help predict and mitigate potential risks to biodiversity resulting from global change,” concludes Gerard Talavera. Reference: “A trans-oceanic flight of over 4,200 km by painted lady butterflies” by Tomasz Suchan, Clément P. Bataille, Megan S. Reich, Eric Toro-Delgado, Roger Vila, Naomi E. Pierce and Gerard Talavera, 25 June 2024, Nature Communications. DOI: 10.1038/s41467-024-49079-2

A heatmap of titan arum, or the corpse flower, shows that the plant’s central towering spike known as the appendix heats up to about 20 degrees Fahrenheit over the ambient temperature when the flower blooms. Credit: Eric Schaller/Dartmouth Dartmouth scientists sniff out the genes — and identify a new chemical compound — that drive titan arum’s pungent odor. The unusual odor of the titan arum, commonly called the corpse flower because its scent is reminiscent of rotting flesh, draws crowds of curious visitors to greenhouses around the world during its rare blooms. What also intrigues scientists is the corpse flower’s propensity for warming itself up just before blooming through a process known as thermogenesis, an uncommon trait in plants that is not well understood. Now, a Dartmouth-led study looks under the hood of the corpse flower to uncover fundamental genetic pathways and biological mechanisms that drive the production of heat and odorous chemicals when the plant blooms. In a paper published on November 4 in PNAS Nexus, scientists led by G. Eric Schaller, professor of biological sciences, also identified a new component of the corpse flower’s odor—an organic chemical called putrescine. Schaller and his collaborators took advantage of several blooms of Morphy, Dartmouth’s 21-year-old corpse flower housed in the Life Sciences Greenhouse, to collect tissue samples for genetic and chemical analysis. The titan arum isn’t a single flower, but a cluster of small flowers hidden within a gigantic central stalk called the spadix, which can grow up to 12 feet tall and is the plant’s most striking visual feature. The plant can go years without flowering—a 5-to-7-year interval is typical—but when it does, it blooms overnight. “The blooms are rare and also short-lived, so we only get a small window to study these phenomena,” Schaller says. A team led by Dartmouth Professor of Biological Sciences Eric Schaller collected tissue samples from Morphy (right), Dartmouth’s 21-year-old corpse flower, to identify fundamental genetic pathways and biological mechanisms that produce the plant’s famous stench. Credit: Eric Schaller/Dartmouth A frilly petal-like layer at the base of the spadix called the spathe unfurls to create a cup around the central stalk that is deep red or maroon on the inside. The spadix begins to heat up, rising by as much as 20 degrees Fahrenheit above the ambient temperature, followed soon after by the release of the plant’s signature scent derived from a cocktail of stinky sulfur-based compounds that attract the flies and carrion beetles that help propagate the plant. Genetic Analysis and Findings When Morphy bloomed in 2016, the researchers gathered nine tissue samples over three nights starting when the spadix temperature peaked—from the lip and base of the spathe, and the towering spike of the spadix known as the appendix. They later added two additional leaf samples to their collection. Alveena Zulfiqar, an exchange research scholar working in the Schaller lab at the time, figured out how to extract high-quality RNA from the tissue, enabling the team to perform RNA sequence analyses and determine the role genes play in heating up the plant and causing the odor. “This helps us see what genes are being expressed and to see which ones are specifically active when the appendix heats up and sends out odor,” says Schaller, a molecular biologist who studies how plant hormones regulate their ability to grow and respond to changes in their environment. He also moonlights as a writer of short fiction, particularly horror fiction: “The corpse flower fits well in both these worlds,” he says.   Thermogenesis, or the ability to generate heat, is common in animals, but rare in plants. In animal cells, a class of proteins called uncoupling proteins interrupt the process of putting chemical energy into storage, releasing them instead as heat, Schaller says. The RNA analysis revealed that the genes associated with the plant counterparts of these proteins, known as alternative oxidases, showed higher expression in tissues extracted when flowering began, particularly in the appendix. Also active at the time were genes involved in sulfur transport and metabolism. The Role of Amino Acids in the Corpse Flower’s Odor To track down the mechanisms set in play by these genes, the team isolated tissues from the plant during a subsequent bloom and, working with collaborators at the University of Missouri, used a technique called mass spectrometry to identify and measure the levels of different amino acids—molecules that make up proteins—in them. As predicted from their RNA analysis, they detected high levels of a sulfur-containing amino acid called methionine, a precursor to sulfur-based compounds known to vaporize easily upon heating, producing pungent odors. The levels of methionine dropped quickly in tissues extracted a few hours later. What came as a surprise, Schaller says, was the detection of elevated levels of another amino acid in tissues taken from the spathe, which serves as a precursor for the production of the compound, putrescine, an odorant found in dead animals when they begin to rot. This study is the first to unravel the secrets of the corpse flower’s stink at a molecular level, determine the processes by which the titan arum regulates temperature, and identify the roles played by different parts of the flowering cluster in creating the carrion cologne that draws pollinators. Morphy holds more mysteries, says Schaller, who is now focused on understanding the triggers that foretell flowering and whether specimens housed together might synchronize blooms to collectively raise the odor level to draw even more pollinators. Reference: “Molecular basis for thermogenesis and volatile production in the titan arum” by Alveena Zulfiqar, Beenish J Azhar, Samina N Shakeel, William Thives Santos, Theresa D Barry, Dana Ozimek, Kim DeLong, Ruthie Angelovici, Kathleen M Greenham, Craig A Schenck and G Eric Schaller, 4 November 2024, PNAS Nexus. DOI: 10.1093/pnasnexus/pgae492 The study was funded by the U.S. National Science Foundation.

Researchers from Brigham and Women’s Hospital and Harvard Medical School found that humans tend to produce antibodies that target the same viral regions repeatedly, called “public epitopes.” Using a tool called VirScan, the team analyzed blood samples from the U.S., Peru, and France, and discovered 376 commonly targeted epitopes. These public epitopes allow viruses to mutate a single amino acid and reinfect previously immune populations. The findings have significant implications for understanding immunity, predicting immune responses, and developing therapies and vaccines. Using a tool called VirScan, Brigham investigators found that people produced shared antibody responses to certain regions of the virus, likely leading to selective pressure and new variants that can repeatedly escape detection by prior immunity. The human body is capable of creating a vast, diverse repertoire of antibodies—the Y-shaped sniffer dogs of the immune system that can find and flag foreign invaders. Despite our ability to create a range of antibodies to target viruses, humans create antibodies that target the same viral regions again and again, according to a new study led by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, and Harvard Medical School. These “public epitopes” mean that the generation of new antibodies is far from random and that a virus may be able to mutate a single amino acid to reinfect a population of previously immune hosts. The team’s findings, which have implications for our understanding of immunity and public health, will be published today (April 6) in the journal Science. “Our research may help explain a lot of the patterns we’ve seen during the COVID-19 pandemic, especially in terms of re-infection,” said corresponding author Stephen J. Elledge, PhD, the Gregor Mendel Professor of Genetics at the Brigham and HMS. “Our findings could help inform immune predictions and may change the way people think about immune strategies.” Alignment of multiple antibodies that use a lysine-specific GRAB motif shows that they recognize their targets in very similar ways. Credit: Stephen J. Elledge, PhD, and Ellen L. Shrock, PhD. Before the team’s study, there were hints, but no clear evidence, that people’s immune systems didn’t target sites on a viral protein at random. In isolated examples, investigators had seen recurrent antibody responses across individuals—people recreating antibodies to home in on the same viral protein location (known as an epitope). But the study by Elledge and colleagues helps explain the extent and underlying mechanisms of this phenomenon. Insights from VirScan Analysis The team used a tool the Elledge lab developed in 2015 called VirScan, which can detect thousands of viral epitopes — sites on viruses that antibodies recognize and bind to — and give a snapshot of a person’s immunological history from a single drop of blood. For the new study, the researchers used VirScan to analyze 569 blood samples from participants in the U.S., Peru, and France. They found that recognition of public epitopes — viral regions recurrently targeted by antibodies — was a general feature of the human antibody response. The team mapped 376 of these commonly targeted epitopes, uncovering exactly where antibodies bind their targets. The team found that antibodies recognized public epitopes through germline-encoded amino acid binding (GRAB) motifs—regions of the antibodies that are particularly good at picking out one specific amino acid. So, instead of randomly choosing a target, human antibodies tend to focus on regions where these amino acids are available for binding, and thus repeatedly bind the same spots. A small number of mutations can help a virus avoid detection by these shared antibodies, allowing the virus to reinfect populations that were previously immune. “We find an underlying architecture in the immune system that causes people, no matter where in the world they live, to make essentially the same antibodies that give the virus a very small number of targets to evade in order to reinfect people and continue to expand and further evolve,” said lead author Ellen L. Shrock, PhD, of the Elledge lab. Immune Strategies and Treatments Interestingly, the team notes that nonhuman species produce antibodies that recognize different public epitopes from those that humans recognize. And, while it is more likely for a person to produce antibodies against a public epitope, some people do produce rarer antibodies, which may more effectively protect them from reinfection. These insights could have important implications for treatments developed against COVID-19, such as monoclonal antibodies, as well as for vaccine design. “The more unique antibodies may be a lot harder to evade, which is important to consider as we think about the design of better therapies and vaccines,” said Elledge. Reference: “Germline-encoded amino acid–binding motifs drive immunodominant public antibody responses” by Ellen L. Shrock, Richard T. Timms, Tomasz Kula, Elijah L. Mena, Anthony P. WestJr, Rui Guo, I-Hsiu Lee, Alexander A. Cohen, Lindsay G. A. McKay, Caihong Bi, Keerti, Yumei Leng, Eric Fujimura, Felix Horns, Mamie Li, Duane R. Wesemann, Anthony Griffiths, Benjamin E. Gewurz, Pamela J. Bjorkman and Stephen J. Elledge, 7 April 2023, Science. DOI: 10.1126/science.adc9498 Funding: This research was supported by the SARS-CoV-2 Viral Variants Program and the Value of Vaccine Research Network, the MassCPR, the National Institutes of Health (1P01AI165072, K99DE031016, AI139538, AI169619, AI170715, and AI170580),  the National Science Foundation (Graduate Research Fellows Program), Pemberton-Trinity Fellowship, Sir Henry Wellcome Fellowship (201387/Z/16/Z), Jane Coffin Childs Postdoctoral Fellowship, Burroughs Wellcome Career Award in Medical Sciences. Elledge is an Investigator with the Howard Hughes Medical Institute. Disclosures: Elledge and co-author Tomasz Kula are founders of TSCAN Therapeutics and ImmuneID. Elledge is a founder of MAZE Therapeutics and Mirimus, and serves on the scientific advisory board of Homology Medicines, TSCAN Therapeutics, MAZE Therapeutics, none of which impact this work. Shrock was a consultant for ImmuneID. Elledge and Kula are inventors on a patent application filed by the Brigham and Women’s Hospital (US20160320406A) that covers the use of the VirScan library to identify pathogen antibodies in blood.

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