Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Indonesia anti-bacterial pillow ODM design

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Taiwan pillow OEM manufacturer

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Vietnam anti-odor insole OEM service

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Breathable insole ODM development Vietnam

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Indonesia insole OEM manufacturer

European antlion (Euroleon nostras) on its dorsal side playing dead. Credit: Professor Nigel R. Franks, University of Bristol Many animals feign death to try to escape their predators, with some individuals in prey species remaining motionless, if in danger, for extended lengths of time. Charles Darwin recorded a beetle that remained stationary for 23 minutes – however the University of Bristol has documented an individual antlion larvae pretending to be dead for an astonishing 61 minutes. Of equal importance, the amount of time that an individual remains motionless is not only long but unpredictable. This means that a predator will be unable to predict when a potential prey item will move again, attract attention, and become a meal. Predators are hungry and cannot wait indefinitely. Similarly, prey may be losing opportunities to get on with their lives if they remain motionless for too long. Thus, death-feigning might best be thought of as part of a deadly game of hide and seek in which prey might gain most by feigning death if alternative victims are readily available. The study, published on March 3, 2021, in the science journal Biology Letters, involved evaluating the benefits of death-feigning in terms of a predator visiting small populations of conspicuous prey. Researchers used computer simulations that utilize the marginal value theorem, a classical model in optimization. Lead author of the paper Professor Nigel R. Franks from the University of Bristol’s School of Biological Sciences, said: “Imagine you are in a garden full of identical soft fruit bushes. You go to the first bush. Initially collecting and consuming fruit is fast and easy, but as you strip the bush finding more fruit gets harder and harder and more time-consuming. “At some stage, you should decide to go to another bush and begin again. You are greedy and you want to eat as many fruits as quickly as possible. The marginal value theorem would tell you how long to spend at each bush given that time will also be lost moving to the next bush. The Art of Wasting Time “We use this approach to consider a small bird visiting patches of conspicuous antlion pits and show that antlion larvae that waste some of the predator’s time, by ‘playing dead’ if they are dropped, change the game significantly. In a sense, they encourage the predator to search elsewhere.” The modeling suggests that antlion larvae would not gain significantly if they remained motionless for even longer than they actually do. This suggests that in this arms race between predators and prey, death-feigning has been prolonged to such an extent that it can hardly be bettered. Professor Franks added: “Thus, playing dead is rather like a conjuring trick. Magicians distract an audience from seeing their sleights of hand by encouraging them to look elsewhere. Just so with the antlion larvae playing dead – the predator looks elsewhere. Playing dead seems to be a very good way to stay alive.” Reference: “Hide-and-seek strategies and post-contact immobility’ by Nigel R. Franks, Alan Worley and Ana B. Sendova-Franks, 3 March 2021, Biology Letters. DOI: 10.1098/rsbl.2020.0892

New research has discovered that the strength of the connection between our brain and internal organs is linked to how we feel about our appearance. Study: Weak internal connections linked to body shame and weight preoccupation. New research has discovered that the strength of the connection between our brain and internal organs is linked to how we feel about our appearance. Published in the journal Cortex, the study is the first to investigate, and first to identify, the association between body image and the brain’s processing of internal signals that occur unconsciously. Carried out by a team of psychologists and neuroscientists at Anglia Ruskin University (ARU), the study found that adults whose brains are less efficient at detecting these internal messages are more likely to experience body shame and weight preoccupation. This research could have therapeutic implications for people suffering with conditions in which body image plays a significant role. For example, the unconscious signals could be made conscious. Further research could even be applied to the clinic as it may be the case that brain responses to gut signals could indicate a predisposition to eating disorders. The study participants – a group of healthy UK adults – first took part in four body image assessments to measure their feelings of body appreciation, body functionality appreciation, body shame, and weight preoccupation. The researchers then carried out measurements of the participants’ internal signals. Some of the messages from the heart and gut are processed at an unconscious level and the nervous system interprets these signals to provide the brain with continuously updated information about the body’s internal state. The strength of the connection between the gut and the brain was measured by recording the electrical activity of both regions at the same time. The researchers also measured brain responses to heartbeats. They found that weaker brain responses to the gut and heart were both significantly associated with greater levels of body shame and weight preoccupation amongst the participants. Senior author Dr. Jane Aspell, Associate Professor of Cognitive Neuroscience at Anglia Ruskin University (ARU), said: “We experience our body both from the inside and out: we can be aware of how our skin and limbs look, but also of how hungry we feel or how strongly our heart is beating during exercise. The brain also continuously processes internal signals that we are not conscious of. “We found that when the brain is less responsive to these implicit signals from inside the body, individuals are more likely to hold negative views about their external bodily appearance. It may be that when the brain has a weaker connection to the internal body, the brain puts more emphasis on the external body and so appearance becomes much more important for self-evaluation.” Lead author Dr. Jennifer Todd, a Postdoctoral Research Fellow at Anglia Ruskin University (ARU), said: “Our research could have implications for those experiencing negative body image, which can have a serious impact on people’s lives. “The gut and heart signal measurements used in our study could potentially act as a biomarker to help identify, or even predict, negative body image and associated conditions, such as eating disorders. Additionally, by training people to become more aware of internal sensations, it might be possible to amplify these unconscious signals. “We need to understand why some brains are better at detecting these internal signals than others. We expect it is partly due to differences in neuro-anatomical connections between the brain and internal organs, and this will be the subject of future research.” Meanwhile, Dr. Jane Aspell will be speaking about her research on the body and sense of self in a talk at the British Science Festival 2021, 7-11 September hosted by the British Science Association at Anglia Ruskin University. The talk will explore research on out of body experiences (OBEs), and she will share case studies from neurological patients. Dr. Aspell’s work investigates what happens in the brain during an OBE and she will present evidence that these are caused by abnormal functioning in parts of the brain that process and combine signals from our bodies. This research on neurological patients sheds light on how the healthy brain generates the experience of one’s self, and what happens when that construction temporarily goes ‘wrong’. Reference: “Weaker implicit interoception is associated with more negative body image: Evidence from gastric-alpha phase amplitude coupling and the heartbeat evoked potential” by Jennifer Todd, Pasquale Cardellicchio, Viren Swami, Flavia Cardini and Jane E. Aspell, 2 September 2021, Cortex. DOI: 10.1016/j.cortex.2021.07.006

A Yale study revealed brain changes in opioid use disorder patients, including altered volume and connectivity in key brain areas and sex-specific differences, pointing to new treatment possibilities. Yale’s study identified structural and functional brain alterations in opioid use disorder patients, offering insights for tailored treatments. Scientists at the Yale School of Medicine have identified structural and functional brain changes in individuals with opioid use disorder (OUD). Using MRI and fMRI data, they observed alterations in key brain regions, including differences in connectivity and volume. These findings, recently published in Radiology, a journal of the Radiological Society of North America (RSNA), could guide the development of new treatments and shed light on the long-term impacts of opioid use. The Scope of the Opioid Epidemic Opioids are a class of drugs that include synthetic opioids such as fentanyl, prescription pain relievers like oxycodone, and illegal narcotics, including heroin. These drugs have a high potential for abuse, and opioid use is a major contributor to drug overdoses in the U.S. According to the National Institute on Drug Abuse, in 2021, approximately 2.5 million adults in the U.S. had opioid use disorder. Provisional data from the Centers for Disease Control and Prevention’s National Center for Health Statistics indicate there were an estimated 81,083 overdose deaths involving opioids in the U.S. during 2023. “We are in the midst of an opioid epidemic, with millions affected worldwide and more than 80,000 deaths related to opioid overdoses in the U.S. last year alone,” said Saloni Mehta, M.B.B.S., postdoctoral associate in the Department of Radiology and Biomedical Imaging at the Yale School of Medicine. “We need to get a better understanding of the system-level neural alterations associated with opioid use disorder.” Tensor-based morphometry (TBM) analysis of T1-weighted MRI scans shows a comparison of brain volumes in participants with opioid use disorder (OUD) and healthy control participants. Widespread volume differences are observed between participants with OUD and healthy controls when accounting for total brain volume. Specifically, the bilateral thalamus, right caudate and orbitofrontal cortex, and right medial temporal lobe show lower volume in participants with OUD compared with healthy controls. The left medial temporal lobe, brainstem, bilateral cerebellum, left insula, and right dorsal posterior cingulate cortex show greater volume in those with OUD compared with healthy controls. All results are shown at P < .05, corrected for multiple comparisons. The color scale indicates the z statistic, whereby blue to pink represents smaller volumes in the OUD group compared with healthy controls, and red to yellow represents larger volumes in the OUD group compared with healthy controls. L = left, R = right. Credit: Radiological Society of North America (RSNA) Study Design and Methodology In the study, Dr. Mehta and colleagues conducted a secondary analysis of data from the National Institutes of Health-funded Collaboration Linking Opioid Use Disorder and Sleep Study (CLOUDS), comparing participants with opioid use disorder on methadone treatment and healthy controls. The data included structural MRI and functional MRI (fMRI) exams performed between February 2021 and May 2023. Resting-state fMRI allows researchers to measure brain activity by detecting changes in blood flow. With resting state fMRI, the connectivity between neural regions—known as resting state networks—can be observed while the brain is at rest. Researchers analyzed CLOUDS structural MRI data for 103 individuals with opioid use disorder and 105 individuals from the control group. They also analyzed the resting state fMRI data on 74 participants with opioid use disorder and 100 controls. The individuals with opioid use disorder were all recently stabilized with medication for the disorder (less than 24 weeks). The median age in the group with opioid use disorder was 37 years, and 40% were women. In the control group, the median age was 27 years, and 55% were women. “Previous studies have been performed on small sample sizes, many of which included no women,” Dr. Mehta said. “Ours is a moderate sample size, approximately half of which is female.” (A) Tensor-based morphometry analysis of a T1-weighted MRI scan shows an interaction between sex and group for brain volume in the right medial prefrontal cortex when accounting for total brain volume. (B) Post hoc box plot shows the average determinant of Jacobian values from the medial prefrontal cortex cluster for each group stratified according to sex. In the healthy control group, male participants had greater volume in the medial prefrontal cortex. In the opioid use disorder (OUD) group, this pattern was reversed. The solid line in the middle of each box represents the median, and the box represents the IQR. Credit: Radiological Society of North America (RSNA) Key Findings on Brain Connectivity Whole-brain analysis revealed structural and functional alterations in opioid receptor-dense regions in the opioid use disorder group compared to healthy controls. In individuals with opioid use disorder, the thalamus and right medial temporal lobe of the brain were smaller in volume, while the cerebellum and brainstem were larger in volume than in controls. In the individuals with opioid use disorder, all these brain regions also had increased functional connectivity compared to controls. “We observed widespread increases in global connectivity in individuals with opioid use disorder,” Dr. Mehta said. “Our goal is to understand better what could have caused these alterations to inform new treatment targets.” Intrinsic connectivity distribution analysis of resting-state functional MRI scans shows a comparison of global resting-state functional connectivity between participants with opioid use disorder (OUD) and healthy control participants. Color scale gradations of yellow indicate greater global connectivity in the bilateral secondary visual areas, left thalamus, right medial temporal lobe, right cerebellum, and brainstem in participants with OUD compared with healthy controls. No clusters of reduced connectivity were observed. L = left, R = right. Credit: Radiological Society of North America (RSNA) Gender Differences in Brain Alterations The results also revealed that women in the group with opioid use disorder had smaller medial prefrontal cortex volume, compared to males in the same group. “We found that alteration patterns in the medial prefrontal cortex—a core region involved in many mental health conditions—were different between men and women in the group with opioid use disorder,” Dr. Mehta said. “This highlights the importance of assessing sex differences in opioid use disorder neuroimaging studies.” Future Directions in Research Dr. Mehta said the study builds a foundation for future research to investigate potential behavioral implications of these brain differences and whether they are permanent. “Our eventual goal is to examine how brain alterations in individuals with opioid use disorder may be linked to outcome measures,” she said. Reference: “Alterations in Volume and Intrinsic Resting-State Functional Connectivity Detected at Brain MRI in Individuals with Opioid Use Disorder” by Saloni Mehta, Hannah Peterson, Jean Ye, Ahmad Ibrahim, Gul Saeed, Sarah Linsky, Iouri Kreinin, Sui Tsang, Uzoji Nwanaji-Enwerem, Anthony Raso, Jagriti Arora, Fuyuze Tokoglu, Sarah W. Yip, C. Alice Hahn, Cheryl Lacadie, Abigail S. Greene, Sangchoon Jeon, R. Todd Constable, Declan T. Barry, Nancy S. Redeker, Henry Yaggi and Dustin Scheinost, 10 December 2024, Radiology. DOI: 10.1148/radiol.240514

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