Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Graphene-infused pillow ODM China

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Vietnam insole ODM design and production

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Thailand custom neck pillow ODM

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Graphene cushion OEM factory in Thailand

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Orthopedic pillow OEM solutions Taiwan

Ascension frigate. Credit: Sam Weber A vast seabird colony on Ascension Island creates a “halo” in which fewer fish live, new research shows. Ascension, a UK Overseas Territory, is home to tens of thousands of seabirds — of various species — whose prey incudes flying fish. The new study, by the University of Exeter and the Ascension Island Government, finds reduced flying fish numbers up to 150km (more than 90 miles) from the island — which could only be explained by the foraging of seabirds. The findings — which provide rare evidence for a long-standing theory first proposed at Ascension — show how food-limited seabird populations naturally are, and why they are often so sensitive to competition with human fishers. Masked booby feeding a chick. Credit: Sam Weber “This study tells us a lot about large colonies of animals and how their numbers are limited,” said Dr. Sam Weber, of the Centre for Ecology and Conservation on Exeter’s Penryn Campus in Cornwall. “These birds are concentrated at Ascension Island during the breeding season, and the intensity of their foraging is naturally highest near the island. “As they use up the most accessible prey located near to the island, they have to travel increasingly long distances to feed, causing the ‘halo’ to expand outwards. “Once individuals can’t find enough food to break even with the energy they expend finding it, the colony stops growing. “Human impacts such as fisheries can interfere with this natural balance and have negative effects on populations of marine top predators like seabirds, even if they don’t directly harm the birds. “What was particularly surprising is the large scale of the footprint we found. It shows that Marine Protected Areas may need to be very large because some predators rely on prey stocks across a huge area.” Masked booby. Credit: Sam Weber The pattern of prey depletion revealed by the study is known as “Ashmole’s halo”, after British ornithologist Philip Ashmole, who first proposed it about 60 years ago after a visit to Ascension Island. For the study, the researchers counted flying fish, tracked seabirds’ foraging trips, and examined their regurgitated food. The nesting seabird species on Ascension that prey on flying fish include frigatebirds, masked boobies, and brown boobies. Reference: “Direct evidence of a prey depletion ‘halo’ surrounding a pelagic predator colony” by Sam B. Weber, Andrew J. Richardson, Judith Brown, Mark Bolton, Bethany L. Clark, Brendan J. Godley, Eliza Leat, Steffen Oppel, Laura Shearer, Karline E. R. Soetaert, Nicola Weber and Annette C. Broderick, 5 July 2021, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2101325118 The research team included the RSPB and the Royal Netherlands Institute for Sea Research. The study was funded by UK Government’s Conflict, Security and Stability Fund and by a Darwin Initiative grant.

Ferns are vascular plants that reproduce through spores and do not have seeds or flowers. A New Study Reveals Ferns’ History of DNA Hoarding and Kleptomania Ferns are infamous for having an enormous number of chromosomes and massive amounts of DNA. A fern no larger than a dinner plate currently holds the record for the highest chromosome count, with 720 pairs packed into each of its nuclei. Scientists have been baffled by ferns’ tendency to hoard DNA, and the intractable size of their genomes has made it challenging to sequence, assemble, and interpret them. Now, two articles recently published in the journal Nature Plants are rewriting history with the first full-length genomes for homosporous ferns, a huge group that encompasses 99% of all modern fern diversity. “Every genome tells a different story,” said co-author Doug Soltis, a distinguished professor with the Florida Museum of Natural History. “Ferns are the closest living relatives of all seed plants, and they produce chemical deterrents to herbivores that may be useful for agricultural research. Yet until now, they’ve remained the last major lineage of green life without a genome sequence.” Analysis of the Ceratopteris genome provides hints for solving the long-standing mystery of why ferns, on average, retain more DNA than other plants. Comparisons to genomes from other groups also led to the surprise discovery that ferns stole the genes for several of their anti-herbivory toxins from bacteria. Credit: David Randall, Western Sydney University Recently, two different research teams independently published the genomes of the flying spider monkey tree fern (Alsophila spinulosa) and Ceratopteris (Ceratopteris richardii). The Ceratopteris genome analysis provides hints for answering the long-standing puzzle of why ferns store more DNA than other plants on average. Comparisons to other species’ genomes revealed that ferns stole the genes for some of their anti-herbivory toxins from bacteria. The Ceratopteris Genome Bucks a Decades-Old Theory, Leaving More Questions Than Answers Since the 1960s, the most favored explanation for why ferns contain so much DNA invoked rampant whole-genome duplications, in which an extra set of chromosomes is accidentally passed on to an organism’s offspring. This can sometimes be beneficial, as all the extra genes can then be used as raw material for the evolution of new traits. In fact, whole-genome duplication has been implicated in the origin of nearly all crop plants. Ceratopteris richardii is extensively used in both research and education for a variety of reasons, including the quick rate at which it completes its lifecycle. Credit: Marchant et al., 2022 in Nature Plants Whole-genome duplication is common in plants and even some animals, but most organisms tend to jettison the extra genetic baggage over time, slimming back down to smaller genomes that are metabolically easier to maintain. “This has been a major point of discussion for the last half-century and has led to all kinds of conflicting results,” said lead author Blaine Marchant, a postdoctoral scholar at Stanford University and former Florida Museum graduate student. “Trying to figure out the evolutionary process underlying this paradox is incredibly important.” With the first fully assembled homosporous fern genomes, scientists were finally prepared to address this question, but getting there wasn’t easy. Sequencing the large, complex genome of Ceratopteris took over eight years of work and the combined effort of dozens of researchers from 28 institutions around the world, including the U.S. Department of Energy Joint Genome Institute. The final result was 7.46 gigabases of DNA, more than double the size of the human genome. If Ceratopteris had bulked up on DNA through repeated genome duplication events, researchers expected large portions of its 39 chromosome pairs would be identical. What they found instead was a mixed bag of repetitive sequences and millions of short snippets called jumping genes, which accounted for 85% of the fern’s DNA. Rather than multiple genome copies, Ceratopteris mostly contains genetic debris accumulated over millions of years. “The functional genes are separated by large amounts of repetitive DNA. And although we’re not yet sure how the Ceratopteris and other fern genomes got so big, it’s clear that the prevailing view of repeated episodes of genome duplication is not supported,” said co-author Pam Soltis, a Florida Museum curator and distinguished professor. The authors note that it’s too early to make any firm conclusions, especially since this is the first analysis of its scope conducted in this group. Cross comparisons with additional fern genomes down the road will help paint a clearer picture of how these plants evolved. Still, the results point to a clear difference in the way homosporous ferns manage their genetic content compared to almost all other plants, Marchant said. “What we seem to be finding is that things like flowering plants, which on average have much smaller genomes than ferns, are just better at getting rid of junk DNA. They’re better at dropping spare chromosomes and even downsizing after small duplications.” Ferns Repeatedly Stole Toxins From Bacteria A closer look at the billions of DNA base pairs within Ceratopteris revealed multiple defense genes that code for a particularly sinister type of pore-forming toxin. These toxins bind to cells, where they become activated and form small, hollow rings that punch their way into the cellular membrane. Water floods into the cells through the resulting holes, causing them to rupture. Pore-forming toxins have been intensively studied by scientists for their potential use in nanopore technology, Marchant explained. Most often, however, they’re found in bacteria. “This is the first concrete evidence of these bacterial toxin-related genes within fern DNA,” Marchant said, noting that the similarity isn’t a coincidence. Rather than evolving this toxin on its own, Ceratopteris appears to have obtained it directly from bacteria through a process called horizontal gene transfer. And given that there were multiple copies of the gene spread out among three separate chromosomes, it’s likely this happened more than once. “What’s fascinating is that the many copies of these genes show up in different parts of the plant,” he said. “Some are highly expressed in the stem and roots, while other copies are expressed solely in the leaves, and others are generally expressed across all tissues. We cannot be sure of the exact function of these genes at this point, but their similarity to the toxin-forming genes in bacteria certainly suggests these genes are defense-related.” This wouldn’t be the first time ferns have incorporated foreign DNA into their genomes. A 2014 study indicates ferns may have evolved their characteristic ability to grow in shady environments by borrowing genes from distantly related plants. However, exactly how organisms separated by millions of years of evolution are able to swap fully functional genes remains unclear. “The mechanisms behind horizontal gene transfer remain one of the least investigated areas of land plant evolution,” Doug Soltis explained. “Over evolutionary timescales, it’s a bit like winning the lottery. Any time a plant is wounded, its interior is susceptible to invasion from microbes, but for their DNA to be incorporated into the genome seems amazing.” The authors say this is merely the first step in a long series of studies with practical applications ranging from the development of novel biopesticides to innovative new conservation strategies. References: “Dynamic genome evolution in a model fern” by D. Blaine Marchant, Guang Chen, Shengguan Cai, Fei Chen, Peter Schafran, Jerry Jenkins, Shengqiang Shu, Chris Plott, Jenell Webber, John T. Lovell, Guifen He, Laura Sandor, Melissa Williams, Shanmugam Rajasekar, Adam Healey, Kerrie Barry, Yinwen Zhang, Emily Sessa, Rijan R. Dhakal, Paul G. Wolf, Alex Harkess, Fay-Wei Li, Clemens Rössner, Annette Becker, Lydia Gramzow, Dawei Xue, Yuhuan Wu, Tao Tong, Yuanyuan Wang, Fei Dai, Shuijin Hua, Hua Wang, Shengchun Xu, Fei Xu, Honglang Duan, Günter Theißen, Michael R. McKain, Zheng Li, Michael T. W. McKibben, Michael S. Barker, Robert J. Schmitz, Dennis W. Stevenson, Cecilia Zumajo-Cardona, Barbara A. Ambrose, James H. Leebens-Mack, Jane Grimwood, Jeremy Schmutz, Pamela S. Soltis, Douglas E. Soltis and Zhong-Hua Chen, 1 September 2022, Nature Plants. DOI: 10.1038/s41477-022-01226-7 “The flying spider-monkey tree fern genome provides insights into fern evolution and arborescence” by Xiong Huang, Wenling Wang, Ting Gong, David Wickell, Li-Yaung Kuo, Xingtan Zhang, Jialong Wen, Hoon Kim, Fachuang Lu, Hansheng Zhao, Song Chen, Hui Li, Wenqi Wu, Changjiang Yu, Su Chen, Wei Fan, Shuai Chen, Xiuqi Bao, Li Li, Dan Zhang, Longyu Jiang, Xiaojing Yan, Zhenyang Liao, Gongke Zhou, Yalong Guo, John Ralph, Ronald R. Sederoff, Hairong Wei, Ping Zhu, Fay-Wei Li, Ray Ming and Quanzi Li, 9 May 2022, Nature Plants. DOI: 10.1038/s41477-022-01146-6 “Horizontal transfer of an adaptive chimeric photoreceptor from bryophytes to ferns” by Fay-Wei Li, Juan Carlos Villarreal, Steven Kelly, Carl J. Rothfels, Michael Melkonian, Eftychios Frangedakis, Markus Ruhsam, Erin M. Sigel, Joshua P. Der, Jarmila Pittermann, Dylan O. Burge, Lisa Pokorny, Anders Larsson, Tao Chen, Stina Weststrand, Philip Thomas, Eric Carpenter, Yong Zhang, Zhijian Tian, Li Chen, Zhixiang Yan, Ying Zhu, Xiao Sun, Jun Wang, Dennis W. Stevenson, Barbara J. Crandall-Stotler, A. Jonathan Shaw, Michael K. Deyholos, Douglas E. Soltis, Sean W. Graham, Michael D. Windham, Jane A. Langdale, Gane Ka-Shu Wong, Sarah Mathews and Kathleen M. Pryer, 14 April 2014, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1319929111 Several of the authors are involved in the current effort to sequence the genomes of all known eukaryotic organisms within a 10-year time frame. Called the Earth Biogenome Project, the endeavor will generate untold genomic resources that researchers will have their hands full analyzing for the foreseeable future. The study was funded by the National Science Foundation, the National Natural Science Foundation of China, the Australian Research Council, Horticulture Innovation Australia, the Ambrose Monell Foundation, the Key R&D Program of Zhejiang Province, the Zhejiang Provincial Natural Science Foundation of China, and the China Agriculture Research System.

Corals in the Indo-Pacific may be more resilient to climate change than those in the Atlantic, according to a new study describing multiple species of thermally tolerant algal symbionts that enable corals to acquire energy from sunlight. Credit: Allison Lewis In a study exploring the various species of algal symbionts associated with reef corals throughout the Indo-Pacific region, researchers discovered a high degree of flexibility in these relationships. This flexibility may enhance these coral systems’ long-term resilience to climate change’s impacts. Facing the effects of global warming and other environmental shifts, corals in the Atlantic Ocean have experienced a sharp decline in recent years. On the other hand, corals in the Pacific and Indian Oceans are faring better. An international team, led by Penn State, has found that the mutualistic relationships between corals and several species of symbiotic algae in the Indo-Pacific may be more adaptable and able to withstand rising ocean temperatures better than those in the Atlantic. Coral reefs are vast geological structures made of calcium carbonate produced by coral animals whose colonies possess dense populations of photosynthetic algae from the family Symbiodiniaceae — herein referred to as “symbionts” — within their tissues. When environmental factors such as increased ocean temperatures disrupt the relationship between the algae and the coral, coral bleaching occurs, causing the colony to turn white. Although corals can recover from bleaching, it may lead to their death, depending on the severity and length of the stress.. “Coral bleaching not only affects the corals themselves but also entire ecosystems of organisms — from invertebrates, like sea urchins and spiny lobsters, to vertebrates, like fish and sea turtles,” said Todd LaJeunesse, professor of biology, Penn State. “It’s important to study the biology of corals and their symbionts so we can predict how they will respond to future environmental changes, especially ocean warming.” Regional Differences in Coral-Symbiont Relationships But, LaJeunesse said, not all corals and symbionts will respond in the same way. That’s because the world’s oceans contain thousands of species of corals, each with their own unique attributes. And, until recently, he said, no one really appreciated the vast diversity of symbiont species and their importance to coral survival. “Scientists previously lumped all the symbionts into a few broad groups,” said LaJeunesse. “My lab’s work over the past several years has been to describe individual species of symbiont so we know what we’re dealing with. Without this information, you really can’t adequately study the ecology, physiology, and biogeography of corals.” As LaJeunesse and his colleagues began to describe symbiont species, they learned that some are specialists — meaning they can only associate with one or a few species of coral hosts — whereas others are generalists — meaning they can associate with many species of coral hosts. In addition, they found that some corals, especially from the Caribbean, rely on specialist symbionts, whereas corals from the Indo-Pacific associate with generalists. The lack of flexibility among Caribbean corals may make them more sensitive to environmental changes while Indo-Pacific corals with more flexible partnerships may withstand greater environmental change. Implications of Thermally Tolerant Symbionts Indeed, according to LaJeunesse, the symbiont species that the team described are important to reef ecosystems because of their ecological dominance and their importance to so many coral species over huge geographic areas. He said, “It’s possible that these species may come to dominate coral communities as Earth’s oceans warm and more sensitive symbionts die out.” The team’s new research, which was recently published in the Journal of Phycology, provides formal descriptions for several host-generalist symbiont species in the Indo-Pacific region. To conduct their study, the researchers collected samples of coral from across the Indo-Pacific, including the reefs of Palau, Thailand, Zanzibar of Tanzania, the Phoenix Islands, the Great Barrier Reef of Australia, and New Caledonia. Next, they extracted the symbiotic algae from these samples and sequenced their DNA. They then identified and described five species of symbionts that are able to associate with a variety of host coral species. “It’s difficult to communicate about things we do not know about, or even have a name for,” said Caleb Butler, a graduate student in biology at Penn State, and first author on the paper. “When we formally describe a species, we are putting a name to these organisms, helping build an identity we can talk about and allow us to connect previous studies with future research. The organisms that we described are widespread, and as oceans warm, these thermally tolerant generalists are likely to expand to new coral communities. Recognizing these distinct species enables informed research into their ecology, and the ability to accurately communicate about the implications of our findings.” Specifically, the symbionts that the team described are in the genus Cladocopium. “Cladocopium are exceptionally biodiverse relative to other coral symbionts; yet very few species from this genus have been successfully cultured,” said Matthew Nitschke, a research scientist from the Australian Institute of Marine Science (AIMS). “One of the species the team described, C. proliferum, can be cultured in a test tube which enables significant progress towards understanding the mechanisms underpinning coral-algal symbiosis, and it has become a model species for such research in Australia. Our Australian team, led by Professor Madeleine van Oppen, are currently using C. proliferum cultures in reef restoration research and development, with a focus on how these algal symbionts contribute to the heat-tolerance of corals.” Reference: “Formal recognition of host-generalist species of dinoflagellate (Cladocopium, Symbiodiniaceae) mutualistic with Indo-Pacific reef corals” by Caleb C. Butler, Kira E. Turnham, Allison M. Lewis, Matthew R. Nitschke, Mark E. Warner, Dustin W. Kemp, Ove Hoegh-Guldberg, William K. Fitt, Madeleine J. H. van Oppen and Todd C. LaJeunesse, 1 May 2023, Journal of Phycology. DOI: 10.1111/jpy.13340 Other authors on the paper include Kira Turnham, Penn State; Allison Lewis, Lawrence Berkeley National Laboratory; Mark Warner, University of Delaware; Dustin Kemp, University of Alabama at Birmingham; Ove Hoegh-Guldberg, University of Queensland; Bill Fitt, University of Georgia; and Madeleine van Oppen, Australian Institute of Marine Science and University of Melbourne. The study was funded by the National Science Foundation, IOC-UNESCO-World Bank and Eberly College at Penn State.

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