Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Vietnam graphene product OEM service

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Customized sports insole ODM Taiwan

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Custom graphene foam processing factory Taiwan

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.ODM pillow factory in China

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Smart pillow ODM manufacturer Taiwan

In his taxonomy of consciousness, Robert Lawrence Kuhn categorizes theories from materialist to nonmaterialist, exploring their implications for AI, immortality, and free will. His findings, based on interviews with numerous experts, are detailed in a 2024 journal article. Kuhn’s taxonomy of consciousness connects various theories to deep questions about human existence and AI, based on his extensive dialogue with over 200 experts. “Out of meat, how do you get thought? That’s the grandest question,” said philosopher Patricia Churchland to Robert Lawrence Kuhn, the producer and host of the acclaimed PBS program Closer to Truth and member of FQxI’s scientific advisory council. Kuhn has now published a comprehensive taxonomy of proposed solutions and theories regarding the hard problem of consciousness. His organizing framework aims to assess their impact on meaning, purpose, and value, as well as on AI consciousness, virtual immortality, survival beyond death, and free will. His work, titled ‘Landscape of Consciousness,’ appeared in the August 2024 issue of the journal Progress in Biophysics and Molecular Biology. FQxI President Anthony Aguirre (left) and Closer To Truth’s Robert Lawrence Kuhn (right) discuss consciousness at FQxI’s 5th International Conference in Banff, Canada. Credit: © Robert Lawrence Kuhn (2016) Exploring the Landscape of Consciousness Since its debut in 2000, Closer To Truth has broadcast 333 episodes, including 30 in collaboration with Foundational Questions Institute, FQxI, a science think tank and funding agency. Kuhn’s article is the culmination of numerous in-depth interviews with experts over the decades.“I have discussed consciousness with over 200 scientists and philosophers,” says Kuhn, who is himself trained in neurophysiology. “Landscape is the product of a lifetime.” Theories and Frameworks The article begins with the classic mind-body problem: How do the felt experiences in our minds relate to the neural processes in our brains? How do mental states, whether sensory, cognitive, emotional, or even noumenal (self-less) awareness, correlate with brain states? “Although there are families of mind-body problems, I focus tightly on phenomenal consciousness: our inner awareness, ‘what it feels like to be’ something,” says Kuhn. FQxI and Closer To Truth’s Robert Lawrence Kuhn (middle) interviews cosmologists Alan Guth (left) and Andrei Linde (right) during an FQxI meeting. Credit: © Robert Lawrence Kuhn (2009) Diverse Perspectives on Consciousness Kuhn presents diverse theories of consciousness, from materialist/physicalist to nonmaterialist/nonphysicalist. These are categorized as Materialism Theories (philosophical, neurobiological, electromagnetic field, computational and informational, homeostatic and affective, embodied and enactive, relational, representational, language, phylogenetic evolution); Non-Reductive Physicalism; Quantum Theories; Integrated Information Theory; Panpsychisms; Monisms; Dualisms; Idealisms; Anomalous and Altered States Theories; and Challenge Theories. “Each explanation is self-described by its adherents,” notes Kuhn. The taxonomy is laid out in the accompanying figure. A taxonomy of consciousness explanations. Credit: © Robert Lawrence Kuhn (2024). Created by Robert Lawrence Kuhn and Alex Gomez-Marin Methodology and Purpose “My purpose must be humble: collect and categorize, not assess and adjudicate,” says Kuhn. “Seek insights, not answers.” Kuhn produced the organizing framework for these diverse theories of consciousness in order to explore their impact on “ultimate questions,” such as meaning, purpose, and value (if any), AI consciousness, virtual immortality, survival beyond death, and free will, he says. “Understanding consciousness at this point cannot be limited to selected ways of thinking or knowing, but should seek expansive yet rational diversity.” Reflections on Theories of Consciousness Having produced an article of around 175,000 words, Kuhn found that his opinions on certain proposals had evolved. “My own hunch, right here, right now might be something of a Dualism-Idealism mashup. Second place might go to some form of Quantum Consciousness, triggered by writing this paper and surprising me. Third place, counterintuitively, to a kind of Eliminative Materialism/Illusionism, combined with Neurobiological and Representational Theories.” But, adds Kuhn, “Smart, serious folks believe radically different theories; what I believe doesn’t much matter.” Reference: “A landscape of consciousness: Toward a taxonomy of explanations and implications” by Robert Lawrence Kuhn, 26 January 2024, Progress in Biophysics and Molecular Biology. DOI: 10.1016/j.pbiomolbio.2023.12.003

A cytokine (blue) secreted by T cells (red) stimulates monocytes (background) to feed on C. albicans hyphae (yellow). Credit: Luo Yu/Leibniz-HKI Researchers just discovered that certain T cells can secrete cytokines that are normally part of the innate immune system. They have now revealed several previously unknown properties of these immune cells that are relevant regarding both autoimmune diseases as well as fighting fungal infections. The study, conducted by researchers from the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI) and an international research team was published in the journal Nature Immunology. T cells belong to the adaptive immune system, which recognizes foreign antigens and specifically fights pathogens. Different T cells perform different functions in this process. So-called T helper cells secrete cytokines that attract other immune cells to the site of infection and trigger inflammation there. However, T helper cells can also counteract inflammation. Better understanding these mechanisms helps in the development of therapeutics against pathogens or autoimmune diseases. “We found a cytokine in a subset of T helper cells, the Th17 cells, that was previously known to be part of the innate immune system,” explains study leader Christina Zielinski. She heads the Department of Infection Immunology at Leibniz-HKI and is a professor at Friedrich Schiller University in Jena. The cytokine, called IL-1α, is strongly pro-inflammatory. “It is a signal molecule for danger. Even the smallest amounts are enough to trigger fever,” Zielinski said. It is thought to be involved in autoimmune diseases such as rheumatoid arthritis in children. Unusual Pathway “We didn’t know how IL-1α is made in T cells and how it gets out of the cells,” says first author Ying-Yin Chao. The research was part of her doctoral thesis, and she now works at an international biotechnology company in Munich, Germany, developing T cell therapies. Through numerous experiments, the researchers eventually found that IL-1α, unlike other cytokines, is produced by a multiprotein complex known as the inflammasome in T cells. This protein complex has very different roles in other cells. “Until now, it was unknown that human T cells had such an inflammasome and that it could be repurposed to produce IL-1α,” Zielinski said. Equally unexpected was the transport pathway out of the cells. “We found via knockout experiments that gasdermin E is responsible for this,” explained Alisa Puhach, second author of the study. This molecule forms pores in cell membranes. Such a mechanism for the export of inflammatory mediators from T cells was previously unknown. Specialization in Fungal Infections? The release of the cytokine IL-1α appears to be restricted to a subset of Th17 cells; other T helper cell types do not produce it. “Th17 cells play an important role in fungal infections,” Zielinski said. The team therefore investigated whether IL-1α is also involved and was able to show that mainly Th17 cells with antigen specificity for the infectious yeast Candida albicans secrete the cytokine. This subset of Th17 cells is therefore likely to be relevant for the defense against infections with the common yeast fungus. In further studies, the researchers now want to find out in which other diseases the pore-forming gasdermin E plays a role in T cells. Reference: “Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation” by Ying-Yin Chao, Alisa Puhach, David Frieser, Mahima Arunkumar, Laurens Lehner, Thomas Seeholzer, Albert Garcia-Lopez, Marlot van der Wal, Silvia Fibi-Smetana, Axel Dietschmann, Thomas Sommermann, Tamara Ćiković, Leila Taher, Mark S. Gresnigt, Sebastiaan J. Vastert, Femke van Wijk, Gianni Panagiotou, Daniel Krappmann, Olaf Groß and Christina E. Zielinski, 5 January 2023, Nature Immunology. DOI: 10.1038/s41590-022-01386-w In addition to other groups at Leibniz-HKI, researchers from the Technical University of Munich, the University of Freiburg, the Technical University of Graz, Austria, and the University of Utrecht, the Netherlands, were involved in the study. The work was supported by the German Research Foundation within the framework of the Collaborative Research Center (SFB) 1054, the SFB/Transregio 124 (FungiNet) and the Cluster of Excellence Balance of the Microverse, as well as by the Emmy Noether Program, the German Center for Infection Research, the Carl Zeiss Foundation and the European Research Council.

Conservation breeding and release is one of a number of species-specific conservation actions included in the meta-analysis. Cuban Crocodile hatchings in the Zapata Swamp breeding sanctuary in August 2019. Credit: Robin Moore, Re:wild A comprehensive meta-analysis examines the success of various conservation interventions globally and across different time periods. A recent study recently published in the journal Science presents the most compelling evidence yet that nature conservation efforts are effective. The research suggests that expanding these conservation measures could have a transformative impact on stopping and reversing the loss of biodiversity. This crisis threatens to lead to ecosystem collapses and a planet less capable of sustaining life, while also mitigating the impacts of climate change. The findings of this first-ever comprehensive meta-analysis of the impact of conservation action are crucial as more than 44,000 species are documented as being at risk of extinction, with tremendous consequences for the ecosystems that stabilize the climate and that provide billions of people around the world with clean water, livelihoods, homes, and cultural preservation, among other ecosystem services. Governments recently adopted new global targets to halt and reverse biodiversity loss, making it even more critical to understand whether conservation interventions are working. “If you look only at the trend of species declines, it would be easy to think that we’re failing to protect biodiversity, but you would not be looking at the full picture,” said Penny Langhammer, lead author of the study and executive vice president of Re:wild. “What we show with this paper is that conservation is, in fact, working to halt and reverse biodiversity loss. It is clear that conservation must be prioritized and receive significant additional resources and political support globally, while we simultaneously address the systemic drivers of biodiversity loss, such as unsustainable consumption and production.” Virunga National Park rangers. Rangers play a key role in safeguarding protected areas, one of the key conservation actions included in the meta-analysis. Credit: Bobby Neptune Although many studies look at individual conservation projects and interventions and their impact compared with no action taken, these papers have never been pulled into a single analysis to see how and whether conservation action is working overall. The co-authors conducted the first-ever meta-analysis of 186 studies, including 665 trials, that looked at the impact of a wide range of conservation interventions globally, and over time, compared to what would have happened without those interventions. The studies covered over a century of conservation action and evaluated actions targeting different levels of biodiversity—species, ecosystems, and genetic diversity. Effective Conservation Strategies The meta-analysis found that conservation actions—including the establishment and management of protected areas, the eradication and control of invasive species, the sustainable management of ecosystems, habitat loss reduction and restoration—improved the state of biodiversity or slowed its decline in the majority of cases (66%) compared with no action taken at all. And when conservation interventions work, the paper’s co-authors found that they are highly effective. For example: Management of invasive and problematic native predators on two of Florida’s barrier islands, Cayo Costa and North Captiva, resulted in an immediate and substantial improvement in nesting success by loggerhead turtles and least terns, especially compared with other barrier islands where no predator management was applied. In the Congo Basin, deforestation was 74% lower in logging concessions under a Forest Management Plan (FMP) compared with concessions without an FMP. Protected areas and Indigenous lands were shown to significantly reduce both deforestation rate and fire density in the Brazilian Amazon. Deforestation was 1.7 to 20 times higher and human-caused fires occurred four to nine times more frequently outside the reserve perimeters compared with inside. Captive breeding and release boosted the natural population of Chinook salmon in the Salmon River basin of central Idaho with minimal negative impacts on the wild population. On average, fish taken into the hatchery produced 4.7 times more adult offspring and 1.3 times more adult second-generation offspring than naturally reproducing fish. “Our study shows that when conservation actions work, they really work. In other words, they often lead to outcomes for biodiversity that are not just a little bit better than doing nothing at all, but many times greater,” said Jake Bicknell, co-author of the paper and a conservation scientist at DICE, University of Kent. “For instance, putting measures in place to boost the population size of an endangered species has often seen their numbers increase substantially. This effect has been mirrored across a large proportion of the case studies we looked at.” Even in the minority of cases where conservation actions did not succeed in recovering or slowing the decline of the species or ecosystems that they were targeting compared with taking no action, conservationists benefited from the knowledge gained and were able to refine their methods. For example, in India the physical removal of invasive algae caused the spread of the algae elsewhere because the process broke the algae into many pieces, enabling their dispersal. Conservationists could now implement a different strategy to remove the algae that is more likely to be successful. One of the studies in the meta-analysis looked at a nationwide REDD+ program In Guyana that reduced tree cover loss by 35%, which is equivalent to 12.8 million tons of avoided carbon emissions. Credit: Andrew Snyder, Re:wild This might also explain why the co-authors found a correlation between more recent conservation interventions and positive outcomes for biodiversity—conservation is likely getting more effective over time. Other potential reasons for this correlation include an increase in funding and more targeted interventions. In some other cases where the conservation action did not succeed in benefiting the target biodiversity compared with no action at all, other native species benefitted unintentionally instead. For example, seahorse abundance was lower in protected sites because marine protected areas increase the abundance of seahorse predators, including octopus. “It would be too easy to lose any sense of optimism in the face of ongoing biodiversity declines,” said study co-author and Associate Professor Joseph Bull, from the University of Oxford’s department of biology. “However, our results clearly show that there is room for hope. Conservation interventions seemed to be an improvement on inaction most of the time; and when they were not, the losses were comparatively limited.” Masked Booby on Redonda Island. This species has benefited tremendously from the removal of invasive predators from the island, one of the key conservation actions included in the meta-analysis. Credit: Robin Moore, Re:wild Economic Perspectives and Future Directions More than half of the world’s GDP, almost $44 trillion, is moderately or highly dependent on nature. According to previous studies, a comprehensive global conservation program would require an investment of between US$178 billion and US$524 billion, focused primarily in countries with particularly high levels of biodiversity. To put this in perspective, in 2022, global fossil fuel handouts–which are destructive to nature—were US$7 trillion. This is 13 times the highest amount needed annually to protect and restore the planet. Today more than US$121 billion is invested annually into conservation worldwide, and previous studies have found the cost-benefit ratio of an effective global program for the conservation of the wild is at least 1:100. “Conservation action works—this is what the science clearly shows us,” said Claude Gascon, co-author and director of strategy and operations at the Global Environment Facility. “It is also evident that to ensure that positive effects last, we need to invest more in nature and continue doing so in a sustained way. This study comes at a critical time where the world has agreed on ambitious and needed global biodiversity targets that will require conservation action at an entirely new scale. Achieving this is not only possible, it is well within our grasp as long as it is appropriately prioritized.” The paper also argues that there must be more investment specifically in the effective management of protected areas, which remain the cornerstone for many conservation actions. Consistent with other studies, this study finds that protected areas work very well on the whole. And what other studies have shown is that when protected areas are not working, it is typically the result of a lack of effective management and adequate resourcing. Protected areas will be even more effective at reducing biodiversity loss if they are well-resourced and well-managed. Moving forward, the study’s co-authors call for more and rigorous studies that look at the impact of conservation action versus inaction for a wider range of conservation interventions, such as those that look at the effectiveness of pollution control, climate change adaptation, and the sustainable use of species, and in more countries. “For more than 75 years, IUCN has advanced the importance of sharing conservation practice globally,” said Grethel Aguilar, IUCN director general. “This paper has analyzed conservation outcomes at a level as rigorous as in applied disciplines like medicine and engineering—showing genuine impact and thus guiding the transformative change needed to safeguard nature at scale around the world. It shows that nature conservation truly works, from the species to the ecosystem levels across all continents. This analysis, led by Re:wild in collaboration with many IUCN Members, Commission experts, and staff, stands to usher in a new era in conservation practice.” Reference: “The positive impact of conservation action” by Penny F. Langhammer, Joseph W. Bull, Jake E. Bicknell, Joseph L. Oakley, Mary H. Brown, Michael W. Bruford, Stuart H. M. Butchart, Jamie A. Carr, Don Church, Rosie Cooney, Simone Cutajar, Wendy Foden, Matthew N. Foster, Claude Gascon, Jonas Geldmann, Piero Genovesi, Michael Hoffmann, Jo Howard-McCombe, Tiffany Lewis, Nicholas B. W. Macfarlane, Zoe E. Melvin, Rossana Stoltz Merizalde, Meredith G. Morehouse, Shyama Pagad, Beth Polidoro, Wes Sechrest, Gernot Segelbacher, Kevin G. Smith, Janna Steadman, Kyle Strongin, Jake Williams, Stephen Woodley and Thomas M. Brooks, 25 April 2024, Science. DOI: 10.1126/science.adj6598 This work was conceived and funded through the International Union for Conservation of Nature (IUCN) by the Global Environment Facility.

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