Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Eco-friendly pillow OEM manufacturer Taiwan

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Thailand OEM factory for footwear and bedding

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Vietnam OEM insole and pillow supplier

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Insole ODM factory in Taiwan

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Orthopedic pillow OEM solutions Vietnam

Researchers found a mutation in the sperm protein FSIP2 lead to infertility in mice. This discovery offers hope for developing infertility treatments. Male infertility affects more than 20 million men globally and is a contributing cause to around 50% of infertility in couples. Frequently, male infertility is the result of defects in the sperm tail, the flagellum, which allows the sperm to swim toward an egg. Males with severe infertility can experience multiple sperm malformations, including flagella that are shortened, irregular, coiled or even absent, preventing them from swimming. In humans, several genetic mutations lead to malformed sperm, including those affecting the sheath that covers the sperm; the mitochondria, which power sperm as they swim; and a tiny sac, the acromosal vesicle, which releases the enzymes that allow one successful sperm to break down the exterior lining of the egg cell to fertilize it. To understand more about the causes of male infertility, Drs Na Li and Ling Sun, research group leaders at Guangzhou Women and Children’s Medical Center, collected sperm samples from infertile men and identified one individual with multiple defects affecting his sperm flagella. Through genetic analysis, they found a mutation in a largely unknown sperm protein, FSIP2 (Fibrous Sheath-Interacting Protein 2), a component of the fibrous sheath. “The fibrous sheath covers the tails of sperm found in humans, mice and other species in which fertilization occurs within the animal’s body”, explains Li. “It offers the sperm tails flexibility and strength, which is necessary for sperm to swim in the dense and sticky medium of the human body before they meet the egg. Interestingly, animals whose sperm swim through water because fertilization occurs outside of the body, such as fish, either do not have the FSIP2 protein or, at most, a defective version.” To study the function of FSIP2, Li, Sun and their team of researchers generated two sets of mice: one in which they recreated the FSIP2 mutation of the human patient and another in which the animals overproduce the FSIP2 protein. They found that mice with the FSIP2 mutation become infertile; their semen contained fewer live sperm and over 50% could not swim forward, even though some of them could still beat their flagella. In contrast, the mice that overproduced the FSIP2 protein remained fertile and, compared to normal mice, had over 7 times more super-long sperm, which could swim faster and be more capable of fertilizing an egg. To understand the reasons for these changes in the sperm flagella, the researchers looked at the composition of the sperm. They found that the sperm of mice with the FSIP2 mutation had lower amounts of the proteins that make up the sheath surrounding the sperm, the mitochondrial power generators and the acrosomal vesicle. In contrast, the sperm of the mice that were overproducing FSIP2 made more sperm tail proteins, particularly in the fibrous sheath, which could allow sperm to swim more easily through the body. They published this discovery in Development. The findings of Li, Sun and their team offer hope that scientists can begin to develop treatments for infertility, either by finding drugs that restore sperm movement or even by finding ways to correct the debilitating mutation that causes the problems in the first place. Ultimately, such treatments could give men suffering from infertility the chance of becoming fathers. Reference: “Hypomorphic and hypermorphic mouse models of Fsip2 indicate its dosage-dependent roles in sperm tail and acrosome formation” by Xiang Fang, Yaser Gamallat, Zhiheng Chen, Hanran Mai, Pei Zhou, Chuanbo Sun, Xiaoliang Li, Hong Li, Shuxin Zheng, Caihua Liao, Miaomiao Yang, Yan Li, Zeyu Yang, Caiqi Ma, Dingding Han, Liandong Zuo, Wenming Xu, Hao Hu, Ling Sun and Na Li, 14 June 2021. Development. DOI: 10.1242/dev.199216

The research shed new light on auxiliary metabolic genes. Researchers identified a unique enzyme in soil viruses that may aid carbon cycling, suggesting AMGs play a role in nutrient dynamics. There are billions of bacteria, fungi, and viruses in every handful of soil, all of which contribute to the sustenance of the cycle of life. Understanding how these microorganisms interact with one another allows scientists to better understand soil health, soil carbon, and nutrient cycling, and even how dead insects decompose. Soil viruses feature genes that seem to have a metabolic role, but they are not essential for normal viral replication. These genes are known as auxiliary metabolic genes (AMGs), and they produce proteins, some of which are enzymes with a variety of roles. Scientists have previously speculated if certain AMG proteins have a role in crucial soil processes such as carbon cycling. To learn more about soil AMGs, researchers determined the atomic structure of a protein expressed by a specific AMG. A three-dimensional structure of the soil virus AMG product, an enzyme known as a chitosanase. The chitosanase is composed of two structural domains (Domain-1 in green and Domain-2 in pink). The active site at which the chemical reaction takes place is highlighted by the four yellow and red sticks. Credit: Clyde Smith/SLAC National Accelerator Laboratory Researchers used high-brightness X-rays generated by the Stanford Synchrotron Radiation Lightsource’s (SSRL) Beam Line 12-2 at the Department of Energy’s (DOE) SLAC National Accelerator Laboratory to irradiate fragile crystallized protein samples. The X-rays struck the proteins in the crystal samples, exposing their molecular structures as well as some of the mystery surrounding their composition. AMGs do not, like many viral genes, help a virus replicate. Instead, they encode for a variety of proteins, each with its own predicted function. The AMG that was expressed was a putative enzyme that plays a key role in how soils process and cycle carbon in the biosphere. Key Insights from AMG Protein Atomic Structure “We saw the location of every atom in the viral protein, which helps us figure out how it functions,” Clyde Smith, SSRL senior researcher and co-author, said. “We were amazed to see that the protein resembles known atomic structures of related bacterial and fungal enzyme families, but also contained totally new pieces.” The detailed atomic structure is unprecedented and reveals for the first time the potential mechanism of this novel enzyme that could play an important role in soil ecology, Janet K. Jansson, chief scientist at the DOE’s Pacific Northwest National Laboratory (PNNL) and co-author, said. “Our collaboration with SLAC has enabled us to decipher previously unknown functions carried out by soil viruses,” Jansson said. The research team from SSRL, PNNL, and the Joint Genome Institute (JGI) at the DOE’s Lawrence Berkeley National Laboratory, recently published their results in Nature Communications. Breaking Down Chitin Researchers think that the viral AMG in the study encodes an enzyme that performs a degradation reaction on chitin. Chitin is the second most abundant carbon biopolymer on the planet after cellulose and is a part of an insect’s exoskeleton and the cell walls of most fungi. The viral AMG in the study is known as a chitosanase protein, and from sequence analysis was identified as a member of the glycosyl hydrolase GH75 family. This protein could be acting like a garden hoe for the soil – i.e., a tool that helps to prepare the soil for vegetables, trees, flowers, and all other kinds of life. Capturing the atomic structure of the chitosanase protein required more than 5,000 images taken from the crystal samples. Piecing together these images revealed that parts of the protein’s structure resembled a known group of carbohydrate-metabolizing enzymes from the glycosyl hydrolase GH45 family. However, the chitosanase protein contained other molecular pieces that did not look like those found in GH45, or in any other known protein structures, which means its role in soil cycling remains open to further studies, Smith said. “There is a part of the enzyme that is completely new and novel. That’s what’s exciting to me as a structural biologist – to see something we have not seen before, and then try to figure out what its role might be,” Smith said. Future research could lead to an understanding of why AMGs exist in the first place since they do not help a virus replicate, Smith said. Additionally, researchers could learn more about other AMGs carried by soil viruses and whether or not they play a functional role in the soil ecosystem. “One of the big questions coming from this finding is, ‘What in the soil needs that carbon in the chitin?’” Smith said. “Answers to questions like this will lead to a deeper understanding about the interaction of the multitude of microorganisms in the soil, the movement of nutrients and essential molecules, and the overall health of the soil.” Reference: “Structural characterization of a soil viral auxiliary metabolic gene product – a functional chitosanase” by Ruonan Wu, Clyde A. Smith, Garry W. Buchko, Ian K. Blaby, David Paez-Espino, Nikos C. Kyrpides, Yasuo Yoshikuni, Jason E. McDermott, Kirsten S. Hofmockel, John R. Cort and Janet K. Jansson, 19 September 2022, Nature Communications. DOI: 10.1038/s41467-022-32993-8 The study was funded by the DOE’s Office of Biological and Environmental Research (BER), JGI, and the DOE’s Environmental Molecular Sciences Laboratory (EMSL). The project was initiated by researchers at PNNL through the soil microbiome SFA funded by BER. It was also supported by a FICUS grant for JGI and EMSL support. The Structural Molecular Biology Program at SSRL is supported by the DOE’s BER and by the National Institutes of Health, and the National Institute of General Medical Sciences.

Intermale-competitions of giraffoid, foreground: Discokeryx xiezhi, background: Giraffa camelopardalis. Credit: Wang Yu and Guo Xiaocong Fossils demonstrate that head-bashing combat contributed to the development of the long necks of giraffes. The authors of the study propose an alternative theory for the origin of the long necks of modern giraffes: giraffes needed them for head-bashing combat they used in competition for mates. This theory is supported by an analysis of an early giraffe ancestor’s unique head and neck fossils, which include disk-shaped helmet-like headgear and highly complex head-neck joints. Since Charles Darwin originally proposed the ideas of adaptive evolution and natural selection, the distinctively long neck of the modern giraffe—the tallest land animal and largest ruminant on Earth—has long been seen as a quintessential example of these processes. According to popular belief, food rivalry led to neck elongation, which enabled giraffes to forage for treetop leaves in the African Savannah woodlands much beyond the reach of other ruminant species. Modeling of high-speed head-butting in Discokeryx xiezhi using finite element analyses, with (A) and without (B) the complicated joints between cranium and vertebrae, showing the stable (A) or over-bending (B) head-neck articulation. Credit: IVPP Others, however, have put forward the “necks-for-sex” theory, which contends that intermale competition-driven sexual selection may also have had a role in the development of the elongated neck. Shi-Qi Wang and colleagues claim that remains of extinct giraffe species can shed light on these evolutionary mechanisms. Here, Wang and his team report and describe a new species of Miocene giraffoid, Discokeryx xiezhi. The fossils, dated to roughly 17 million years ago, indicate that this ancient giraffoid species had helmet-like headgear and particularly complex head and neck joints. The fossil community in the Junggar Basin at ~17 million years ago. Discokeryx xiezhi are in the middle. Credit: Guo Xiaocong According to the researchers, these peculiar morphological characteristics show an adaption for fierce head-butting behavior. In fact, the authors suggest that Discokeryx xiezhi may have possessed the most optimized head-butting head and neck adaptation yet identified in vertebrate evolution. Moreover, tooth enamel isotope data from these fossils suggest that the species also likely filled a specific ecological niche in the ecosystem unavailable to other contemporary herbivores. In total, the scientists suggest that early giraffoid evolution is more complex than previously known, where, in addition to competition for food, sexual combat likely played an important role in shaping the group’s long and uniquely adapted necks. Reference: “Sexual selection promotes giraffoid head-neck evolution and ecological adaptation” by Shi-Qi Wang, Jie Ye, Jin Meng, Chunxiao Li, Loïc Costeur, Bastien Mennecart, Chi Zhang, Ji Zhang, Manuela Aiglstorfer, Yang Wang, Yan Wu, Wen-Yu Wu and Tao Deng, 3 June 2022, Science. DOI: 10.1126/science.abl8316

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