Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Eco-friendly pillow OEM manufacturer Thailand

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Taiwan orthopedic insole OEM manufacturing site

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.China foot care insole ODM expert

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Latex pillow OEM production in Taiwan

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Graphene sheet OEM supplier Vietnam

New research reveals that butterflies, moths, and aquatic caddisflies share DNA “blocks” dating back over 200 million years, identified through a tool developed by scientists at universities in the UK, Germany, and Japan. This discovery, which illustrates the linkage and evolution of chromosomes among these species, not only sheds light on their genetic history but also potentially aids in the study of chromosome evolution in other organisms. New research indicates that butterflies and moths share “blocks” of DNA dating back more than 200 million years. Researchers from the Universities of Exeter (UK), Lübeck (Germany), and Iwate (Japan) developed a method to analyze the chromosomes of various butterflies and moths. The chromosomes of the African Monarch butterfly. The red dots highlight the ends of each chromosome using a DNA probe linked to a fluorescent reporter. Credit: University of Exeter They found blocks of chromosomes that exist in all moth and butterfly species, and also in Trichoptera – aquatic caddisflies that shared a common ancestor with moths and butterflies some 230 million years ago. Lepidoptera’s Varying Chromosome Numbers Moths and butterflies (collectively called Lepidoptera) have widely varying numbers of chromosomes – from 30 to 300 – but the study’s findings show remarkable evidence of shared blocks of homology (similar structure) going back through time. “DNA is compacted into individual particles or chromosomes that form the basic units of inheritance,” said Professor Richard ffrench-Constant, from the Centre for Ecology and Conservation on Exeter’s Penryn Campus in Cornwall. “If genes are on the same ‘string’, or chromosome, they tend to be inherited together and are therefore ‘linked’. “However, different animals and plants have widely different numbers of chromosomes, so we cannot easily tell which chromosomes are related to which. “This becomes a major problem when chromosome numbers vary widely – as they do in the Lepidoptera. A male and female African monarch mating. Credit: University of Exeter “We developed a simple technique that looks at the similarity of blocks of genes on each chromosome and thus gives us a true picture of how they change as different species evolve. “We found 30 basic units of ‘synteny’ (literally meaning ‘on the same string’ where the string is DNA) that exist in all butterflies and moths, and go back all the way to their sister group the caddisflies or Trichoptera.” Butterflies as Conservation and Evolution Models Butterflies are often seen as key indicators of conservation, and many species worldwide are declining due to human activity. However, this study shows that they are also useful models for the study of chromosome evolution. The study improves scientific understanding of how moth and butterfly genes have evolved and, importantly, similar techniques may also provide insights about the evolution of chromosomes in other groups of animals or plants. Reference: “Lepidopteran Synteny Units reveal deep chromosomal conservation in butterflies and moths” by Walther Traut, Ken Sahara and Richard H ffrench-Constant, 13 June 2023, G3: Genes, Genomes, Genetics. DOI: 10.1093/g3journal/jkad134

A Sierra Nevada red fox. Credit: Keith Slausen USFS/PSW – US Forest Service There’s an elusive fox roaming the southern Sierra Nevada, and experts are trying to learn more about its behavior and breeding success by analyzing one of the few traces of its presence — poop. Living in areas above 9,000 feet (2,700 meters) in elevation, the fox is smaller than most, has fuzzy paws, and a thick fur coat–all adaptations to help it survive the heavy winter snows and challenging alpine conditions. Its fur can range in color from red to black to grayish-brown. Recently proposed to be listed as an endangered species by the U.S. Fish and Wildlife Service, the southern population of the Sierra Nevada red fox is estimated to consist of fewer than 50 individuals. Recent hybridization with non-native red foxes that escaped from fur farms and other alpine foxes that traveled from Nevada or the Rocky Mountains has put this subspecies at risk of going extinct. Recently proposed to be listed as an endangered species by the U.S. Fish and Wildlife Service, the southern population of the Sierra Nevada red fox is estimated to consist of fewer than 50 individuals. Credit: National Park Service “With most endangered species, we’re trying to manage the landscape to provide a path to recovery. For this species, we’re trying to preserve the Sierra Nevada red fox genes while ensuring sufficient habitat exists,” said Stephanie Eyes, a biologist with the Service’s Sacramento Fish and Wildlife Office. Collecting information on the fox is difficult. It’s rarely seen — deftly avoiding trail cameras and live traps. However, ongoing research is helping to paint a picture of the fox, its behavior, and breeding success. Since 2011, Cate Quinn, a post-doctoral researcher in UC Davis’ Mammalian Ecology and Conservation Unit, has been studying the fox by collecting its scat (the term preferred over poop, at least in the science world). In the science world, this type of tracking is called noninvasive genetic monitoring. It typically involves collecting DNA from scat, urine, or hairs left behind in the great outdoors in lieu of using tracking collars that require capturing live animals. “With most endangered species, we’re trying to manage the landscape to provide a path to recovery. For this species, we’re trying to manage a genetic landscape and preserve the Sierra Nevada red fox genes,” said Stephanie Eyes, biologist with the Service’s Sacramento Fish and Wildlife Office. Credit: Stephanie Eyes/USFWS “The DNA found in scat is very powerful. You can tell which fox it came from and who they’re related to. This information helps us learn more about their movements across the landscape, their lifespan, and which other types of foxes they’re breeding with,” said Quinn. Each year, starting in the late summer, Quinn and her team head out to four core locations between the northern border of Yosemite National Park and Highway 4 in the Sonora Pass to collect scat. The team collects anything that could be fox scat (some turn out to be coyote) and takes it back to the lab for analysis. While some trips can be completed in a day, others require backpacking across rocky mountain ridges for up to five days, constantly scanning the ground for scat, and hauling any scat collected the entire trip. Approximately 400–500 samples are collected each year. The samples help create the “family tree” of the individuals living in the high Sierra. Cate Quinn, a post-doctoral researcher in UC Davis’ Mammalian Ecology and Conservation Unit, collects fox scat in the high Sierras. “The DNA found in scat is very powerful. You can tell which fox it came from and who they’re related to,” said Quinn. Credit: C. Quinn “This annual census enables us to take the pulse of the Sierra Nevada red fox population. The information helps us answer key questions like: Are there big dramatic changes in the population? Is mortality going up or down? Is reproduction stopping?” said Quinn. In 2018, Quinn added dogs from Rogue Detection Teams, owned by Jennifer Hartman, to the team of scat collectors. The dogs are specially trained to sniff out fox scat, and their keen sense of smell can find it more easily than the human eye, especially in areas where the foxes’ presence is rare or unknown. The dog and its handler travel to several locations each year to support the collection efforts. They, too, backpack for several days across the high Sierra sniffing for traces of the fox. Rogue Detection Teams train dogs to sniff out fox poop, and their keen sense of smell can find poop more easily than the human eye, especially in areas where the foxes’ presence is rare or unknown. This dog, named Filson, has tracked fox scat as seen in the foreground. Courtesy of Rogue Detection Teams Once back in the lab, the DNA analysis tells a more detailed story. Quinn and her team have been able to identify and track the same individuals for several years and have found that the foxes are long-lived. They also travel long distances. One individual she’s tracked traveled more than 60 miles in just one year. The DNA also shows that hybridization continues with non-native foxes, however, that’s not entirely bad. There’s a concern that too much inbreeding between pure Sierra Nevada red foxes could lead to more detrimental impacts to the species than some level of hybridization. Breeding with non-native or other alpine foxes — to a certain point — could be helpful for maintaining the Sierra Nevada red fox DNA and ensuring the longevity of the species. “The foxes have been here for thousands of years, which shows that they’re resilient. That gives me hope that they will persist if we can figure out ways to keep them going,” said Quinn. Back in the lab, Stevi Vanderzwan, laboratory manager for the Mammalian Ecology and Conservation Unit at UC Davis, processes scat and analyzes the DNA. The samples help create the “family tree” of the individuals living in the high Sierra. Credit: Don Preisler/UC Davis While more information is gathered, efforts are already underway to help the fox. A group of representatives from the Service, National Park Service, U.S. Forest Service, California Department of Fish and Wildlife, Marine Corps Mountain Warfare Training Center, and biologists from universities and the private sector are developing a conservation strategy for the Sierra Nevada red fox. This strategy will guide and prioritize recovery actions, such as translocations and possibly introducing other alpine foxes to support breeding. Additionally, the Forest Service, Park Service, and Department of Defense have resource management plans on the lands they manage that minimize forest fragmentation and limit activities that could disturb Sierra Nevada red fox breeding and denning areas. “This research is helping us get a better understanding of where the foxes are living, their breeding and movement, and how their home ranges and genetics are changing over time. This information is incredibly useful as we determine ways to help recover this unique species,” said Eyes. While Quinn’s research will continue to shed light on the secretive fox, partners are optimistic that this species will remain part of the Sierra landscape, even if the only trace of their presence are the brown piles they leave behind.

African clawed frogs are known for their flat bodies, vocal organs, and claws on the first three toes of the hind feet. Credit: Adam Bewick Researchers at McMaster University discovered eight different sex chromosomes in 11 species of African clawed frogs, revealing surprising genetic diversity. The study found these chromosomes in genome regions with high genetic recombination, challenging existing theories about sex-determining gene evolution. This research highlights how crucial biological traits like sexual differentiation can evolve rapidly through newly developed genes. Genetic Diversity in African Clawed Frogs Researchers at McMaster University have discovered surprising genetic diversity in how sex is determined in the African clawed frog, one of the most extensively studied amphibians in the world. Through genomic analysis, scientists identified eight distinct sex chromosomes across 11 species of the frog. Many of these chromosomes may carry newly evolved genes responsible for triggering male or female development. Before this study, researchers were aware of only three sex chromosomes in the species, making this a groundbreaking discovery in the field of genetic evolution. The African clawed frog is used as a model organism for biological research because of its close evolutionary relationship to humans. Credit: Adam Bewick “In these frogs, we’ve discovered extraordinary variation even among closely related species, which allows us to explore how important things like sex determination evolve rapidly,” says Ben Evans, a professor in the Department of Biology at McMaster and lead author of a new study in the journal Molecular Biology and Evolution. Evans conducted the work with colleagues from the Czech Republic, France, the USA, and South Africa. The African clawed frog is used as a model organism for biological research because of its close evolutionary relationship to humans, and because early development occurs externally, allowing fundamental processes to be readily observed and manipulated. The frogs are found in sub-Saharan Africa and live in slow-moving or stagnant water. They are known for their flat bodies, vocal organs that can produce sound underwater, and claws on the first three toes of the hind feet, which they use to tear food apart. Surprising Locations of Sex-Determining Genes In this study, the researchers pinpointed the locations of the newly identified sex chromosomes, which added to their surprise. Prevailing theory had suggested that sex-determining genes might typically arise in regions of the genome with a low rate of recombination – the exchange of genetic material within each parent that creates new mixtures of traits in their offspring. Evolutionary Insights into Sex Determination Instead, they found these newly evolved genes were almost universally located in regions where genetic recombination is high, raising questions about how and why the genetic basis of very important biological traits – such as sexual differentiation – may evolve so quickly, and how new genes and genetic function arise. “If you conducted these same tests within some even older groups such as most mammals or all birds, you would find that their sex chromosomes are all the same,” explains Evans. “But this group of frogs — in sharp contrast — has incredible variation.” “It is very likely that new genes arose many times in these frogs to orchestrate sexual differentiation, by acting as an ‘on-off switch’ or a ‘male-female switch’ at the top of the developmental cascade,” he says. Historical Context and Ongoing Research In 2015, Evans—who has studied the African clawed frog for over two decades—led a team which discovered six new species and added another back to the list of known species, providing the foundational information for this current work. Reference: “Rapid Sex Chromosome Turnover in African Clawed Frogs (Xenopus) and the Origins of New Sex Chromosomes” by Ben J Evans, Václav Gvoždík, Martin Knytl, Caroline M S Cauret, Anthony Herrel, Eli Greenbaum, Jay Patel, Tharindu Premachandra, Theodore J Papenfuss, James Parente, Marko E Horb and John Measey, 12 December 2024, Molecular Biology and Evolution. DOI: 10.1093/molbev/msae234

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