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Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
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Taiwan custom product OEM/ODM services

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Thailand ODM expert for comfort products

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.China neck support pillow OEM

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Private label insole and pillow OEM Indonesia

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.ODM service for ergonomic pillows Taiwan

Scientists have discovered the world’s oldest inhabited termite mounds along the Buffels River in Namaqualand, dating back 34,000 years, challenging our understanding of prehistoric life and carbon storage. These mounds, still active and studied for their unique carbon sequestration properties, offer insights into past climates and underscore the importance of natural processes in combating climate change. (The termite mound above is a stock image and not the actual mound described in the Namaqualand study.) Researchers in Namaqualand have found the world’s oldest termite mounds, dating 34,000 years, revealing key insights into ancient climates and carbon storage. In a remarkable breakthrough, scientists have uncovered the world’s oldest inhabited termite mounds along the Buffels River in Namaqualand. These mounds, which date back an astonishing 34,000 years, are transforming our understanding of prehistoric life, climate, and carbon storage. An Ancient Marvel These termite mounds, called “heuweltjies” in Afrikaans, meaning “little hills,” are inhabited by the southern harvester termite, Microhodotermes viator, explains lead author on the study, Dr. Michele Francis, a Senior Lecturer (Extraordinary), in the Department of Soil Science in the Faculty of AgriSciences at Stellenbosch University (SU). “Recent radiocarbon dating has revealed that these mounds are far older than any previously known, with some dating as far back as 34,000 years – that’s older than the iconic cave paintings in Europe and even older than the Last Glacial Maximum, when vast ice sheets covered much of the northern hemisphere.” Aerial views of Namaqualand heuweltjies covered by spring flowers. The flowers grow preferentially on the mounds because they are richer in nutrients than the surrounding soil. Credit: Jannick Niewoudt; Alastair Potts The mounds are still inhabited by termites, and the radiocarbon dating of the organic carbon within these mounds has shown ages ranging from 13,000 to 19,000 years, while the carbonate dates back up to 34,000 years. This make the Buffels River mounds the oldest active termite mounds to be dated so far with both organic and inorganic carbon. The previous oldest inhabited mounds from different species from Brazil are 4000 years old. “To put it in perspective, these termite mounds were already ancient when woolly mammoths still roamed the Earth. During the Last Glacial Maximum, around 20,000 years ago, massive ice sheets covered parts of North America, Europe, and Asia. These mounds were already thousands of years old by then, providing a living archive of environmental conditions that shaped our world,” says Francis. A Peek into Prehistoric Climate These ancient mounds are more than just a historical curiosity; they serve as valuable records of prehistoric climate condition, says Francis. “The heuweltjies have shown that during their formation, the region experienced significantly more rainfall than today. This wetter climate allowed for minerals such as calcite and gypsum to dissolve and move down to the groundwater. This process is crucial in understanding natural carbon sequestration processes. What is interesting is that Namaqualand still has sporadic episodes of intense rainfall, like last winter, which would re-activate the process.” A termite mound uncovered in the study. Credit: Teneille Nel Why It Matters Not only are these the oldest termite mounds on earth, but they also offer two mechanisms to sequester CO2, adds Francis. Firstly, the harvesting activities of termites inject younger organic material deep into their nests, leading to continuous renewal of important soil carbon reservoirs at depth, where they are preserved for longer than when still at the surface. Secondly, these calcareous termite mounds offer a way to remove CO2 when the soil mineral calcite dissolves. This is a long-term carbon storage that companies are seeking to replicate in enhanced weathering or ocean alkalinity enhancement projects, and is important for calculating a country’s carbon budget as laid out in the Paris Agreement, and accounted for during land use change. A Call for Global Recognition “The discovery of these mounds is akin to being able to read an ancient manuscript that changes everything we thought we knew about history. Their age, and the insights they provide into ancient ecosystems, make them a candidate for global recognition as a natural wonder,” says Francis. “By studying these mounds, scientists can gain a better understanding of how to combat climate change, utilizing nature’s own processes for carbon sequestration. They also highlight the importance of preserving our natural world, as these tiny engineers have been shaping our environment for tens of thousands of years.” Conclusion “The discovery of the world’s oldest termite mounds in Namaqualand is a testament to the incredible history hidden beneath our feet. These mounds not only illuminate the past but also offer vital clues for our future. As we continue to uncover the secrets of these ancient structures, they stand as a reminder of the delicate interplay between climate, environment, and life on earth,” concludes Francis. Reference: “Calcareous termite mounds in South Africa are ancient carbon reservoirs” by M.L. Francis, L. Palcsu, M. Molnár, T. Kertész, C.E. Clarke, J.A. Miller and J. van Gend, 25 March 2024, Science of The Total Environment. DOI: 10.1016/j.scitotenv.2024.171760 The pioneering research was conducted by a dedicated team from SU’s Departments of Soil Science and Earth Sciences, in collaboration with experts from the Institute for Nuclear Research in Hungary. The heuweltjies are now being studied further by a SU PhD student as part of a joint United States (National Science Foundation) – South Africa (National Research Foundation) collaboration grant to find out more about their carbon storage potential. Funding: Water Research Commission South Africa (project K5-2825), National Research Foundation of South Africa, European Union, and the State of Hungary, co-financed by the European Regional Development Fund in the project of GINOP-2.3.2-15-2016-00009 ‘ICER

New research using electronic tags and sonar data shows that large marine predators like sharks and tunas often dive into the deep mesopelagic zone, interacting with its dense layer of organisms for feeding and possibly other purposes. This zone is crucial for both ecological balance and commercial fishing, requiring careful study and conservation to prevent irreversible damage. Data from over 300 tags on large marine predators, along with shipboard sonar, point to the ecological importance of the ocean’s twilight zone. If you’ve ever witnessed a shark breach the water—whether in person or somewhere on the Internet—that fleeting but awe-inspiring moment is just a small fraction of the time it spends at the surface of the ocean. Most of the time sharks and other large marine predators are out of sight, begging the question—where do they go? New Insights From a Comprehensive Study A new study demonstrates that large predatory fishes like sharks, tunas, and billfish make a surprising number of visits to the deep ocean—particularly the mesopelagic zone, which is found between 200 to 1,000 meters below the surface. This area, also called the ocean’s twilight zone, has been overlooked as critical habitat for large predator species, according to the study. The paper was published on November 6 in the journal Proceedings of the National Academy of Sciences. A new study demonstrates that large predatory fishes like sharks, tunas, and billfish make a surprising number of visits to the deep ocean—particularly the ocean’s twilight zone, which has been overlooked as critical habitat for large predator species. Credit: Tiger Shark /©Tom Burns Collaborative Research Efforts Led by Camrin Braun, an assistant scientist at the Woods Hole Oceanographic Institution (WHOI), the study incorporated an astonishing amount of data from multiple scientific partners. He and the co-authors synthesized data from electronic tags, shipboard sonar, Earth-observing satellites, and data-assimilating ocean models to quantify the ecological significance of deep diving for large pelagic predators. They emphasize that a healthy mesopelagic zone provides numerous benefits and ecosystem services to humans as well. Deep Ocean Habits of Predators “No matter what top predator you look at, or where you look at them in the global ocean, they all spend time in the deep ocean,” Braun said. “All of these animals that we think of as being residents of the surface ocean, use the deep ocean way more than we previously thought.” The scientists leveraged data from 344 electronic tags over the course of 46,659 tracking days for 12 species in the North Atlantic Ocean, including white sharks, tiger sharks, whale sharks, Yellowfin tuna, swordfish, and more. A new study demonstrates that large predatory fishes like sharks, tunas, and billfish make a surprising number of visits to the deep ocean—particularly the ocean’s twilight zone, which has been overlooked as critical habitat for large predator species. Credit: Blue Shark offshore, Cape Cod/© Eric Savetsky Understanding Deep Scattering Layer Movements The diving patterns of these fish recorded by the tags were then matched with sonar data that showed the daily movements of the deep scattering layer (DSL)—a zone where a huge number of small fish and marine organisms are packed so densely that scientists first using sonar mistook the layer for the ocean floor. During the day, animals in the DSL inhabit the mesopelagic zone. But when the sun sets, many of these individuals—like fish, mollusks, crustaceans, and others—swim to surface waters to feed. When the sun reemerges over the horizon, scattering light over the surface, they descend back to the twilight zone where they will remain until nightfall. This daily rhythm is called Diel Vertical Migration and is a pattern that scientists at WHOI have been studying for decades. Converging Data and Surprising Findings Alice Della Penna, co-author and collaborator at the University of Auckland, New Zealand, who specializes in acoustics, said that it was surprising to see the data sets match so well. “When we looked at this specific process from different perspectives, from the diving and the acoustics together, seeing that everything was falling into place was very exciting.” Feeding Patterns and Anomalous Behaviors After years of collecting and analyzing data, the new paper helps shed light on the predators who are attuned to the DSL, presumably to hunt smaller prey, and the animals who often diverge from the daily vertical migration patterns, leading to further questions about why they are diving so deep, if not to feed. “Several species aligned perfectly with the expectations that they’re diving to feed, but there are behaviors that aren’t just for feeding,” Braun said. Swordfish for example, follow the Diel Vertical Migration pattern like clockwork. But there are some “really surprising deviations from that behavior,” he explains—”like instead of diving down to 1,500 feet, a swordfish goes to 3,000 or 6,000 feet, much deeper than we would expect for that to be feeding behavior.” Exploring Other Motivations for Deep Diving That means they could be diving for other reasons that are not fully understood. Previous work has pointed to these vertical movements may be serving to avoid predators or aid in navigation, according to the study. Despite the anomalies, all of the large species included in the study interreacted with the mesopelagic organisms in one way or another, finding that it’s worth it for these predators to dive deep into a seemingly inhospitable part of the ocean where there is little light, the pressure is high and temperatures are near freezing. Ecosystem Services of the Mesopelagic Zone “Sharks and tunas are evolutionarily a long way apart with very different sensory systems. And yet still both of those groups find that it’s worthwhile to do that type of behavior,” said Simon Thorrold, fish ecologist at WHOI and co-author on the study. With the large number of fish and organisms making this trek, Thorrold said that these species are potentially moving a hefty amount of carbon dioxide from the surface into the deep ocean where it will stay for centuries—a potentially significant ecosystem service of the mesopelagic that is not yet quantified. Implications for Conservation and Commercial Fishing Since the twilight zone is clearly important to many large species that are fished commercially, “this deep-sea biomass contributes ecosystem services that are worth a considerable amount of money,” Thorrold, said. The paper stresses that it is in everyone’s interest to keep the mesopelagic intact, and that it is important to study these deep ocean food webs further before fishing or extracting activities occur. The paper states that “the overlap in ongoing fishing effort and pelagic predator distributions, expected climate-induced changes in pelagic ecosystems and the potential extraction of mesopelagic biomass,” can put this critical ecosystem in jeopardy. The Risks of Premature Exploitation “We’re finding that the mesopelagic is providing an important support for other parts of the ocean,” Della Penna said. “If we start to exploit these mesopelagic ecosystems before we know how they work, there’s a really big risk of causing damage that is not easily reversible.” Key Takeaways Data from electronic tags, shipboard acoustic data, Earth-observing satellites, and data-assimilating ocean models, find that the ocean’s mesopelagic zone, also called the twilight zone, is ecologically significant to many large marine fish that are thought of as surface dwellers. These large marine predators, like sharks and tunas, dive deep into the twilight zone, often to follow the movements of a dense layer of prey organisms, called the deep scattering layer. “Several species aligned perfectly with the expectations that they’re diving to feed, but there are behaviors that aren’t just for feeding,” lead author Camrin Braun said. Swordfish, for example, follow the Diel Vertical Migration pattern like clockwork. But there are some “really crazy deviations from that behavior,” meaning they could be diving for other reasons that are not fully understood. The paper stresses that it is in everyone’s interest to keep the mesopelagic zone intact, and it’s important to study these deep ocean food webs further before fishing or extracting activities occur. Reference: “Linking vertical movements of large pelagic predators with distribution patterns of biomass in the open ocean” by Camrin D. Braun, Alice Della Penna, Martin C. Arostegui, Pedro Afonso, Michael L. Berumen, Barbara A. Block, Craig A. Brown, Jorge Fontes, Miguel Furtado, Austin J. Gallagher, Peter Gaube, Walter J. Golet, Jeff Kneebone, Bruno C. L. Macena, Gonzalo Mucientes, Eric S. Orbesen, Nuno Queiroz, Brendan D. Shea, Jason Schratwieser, David W. Sims, Gregory B. Skomal, Derke Snodgrass and Simon R. Thorrold, 6 November 2023, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2306357120 Funding for this research was provided by The Coastal Research Fund in Support of Scientific Staff and the Investment in Science Fund at the Woods Hole Oceanographic Institution (to CDB), the WHOI President’s Innovation Fund and Postdoctoral Scholar Program at Woods Hole Oceanographic Institution with funding provided by the Dr. George D. Grice Postdoctoral Scholarship Fund (to MCA), UK Natural Environment Research Council (to DWS), the European Research Council (to DWS), a Marine Biological Association Senior Research Fellowship (to DWS) and the King Abdullah University of Science and Technology (baseline research funds to MLB). BCLM was supported by the projects IslandShark (PTDC/BIA-BMA/32204/2017), AEROS-Az (ACORES-01-0145-FEDER-000131), MEESO (EU H2020-LC-BG-03-2018), and Mission Atlantic (H2020-LC-BG-08-2018-862428). This work was part of the Woods Hole Oceanographic Institution’s Ocean Twilight Zone Project, funded as part of the Audacious Project housed at TED.

Inheritance, as it pertains to genetics, refers to a trait or variants encoded in DNA and transferred from parent to child during reproduction. The Discovery Indicates That Epigenetic Inheritance Could Occur More Frequently Than Previously Believed A fundamental discovery concerning a driver of healthy development in embryos might rewrite our understanding of what we can inherit from our parents and how their life experiences shape us. The new study reveals that epigenetic information, which sits on top of DNA and is typically reset between generations, is more commonly passed down from mother to child than previously thought. The research, led by researchers from the Walter and Eliza Hall Institute in Melbourne, Australia, greatly expands our knowledge of which genes have epigenetic information passed from mother to offspring and which proteins are critical for controlling this peculiar process. Epigenetics is a rapidly expanding field of science that studies how our genes are turned on and off to enable one set of genetic instructions to produce hundreds of different cell types in our body. Environmental factors such as our nutrition can impact epigenetic changes, but these changes do not alter DNA and are not generally passed down from parent to child. Epigenetic tags (orange and blue) on inactive DNA. Researchers say epigenetic tags could be passed onto offspring more often than previously thought. Credit: Still from WEHI.TV’s animation “X Inactivation and Epigenetics” by Etsuko Uno Despite the fact that a small subset of “imprinted” genes may pass epigenetic information down the generations, relatively few other genes have up to this point been shown to be influenced by the mother’s epigenetic state. According to recent research, the supply of a certain protein in the mother’s egg may have an impact on the genes that drive the skeletal patterning of children. Maternal Epigenetic Transmission Chief investigator Professor Marnie Blewitt said the findings initially left the team surprised. “It took us a while to process because our discovery was unexpected,” Professor Blewitt, Joint Head of the Epigenetics and Development Division at WEHI, said. “Knowing that epigenetic information from the mother can have effects with life-long consequences for body patterning is exciting, as it suggests this is happening far more than we ever thought. It could open a Pandora’s box as to what other epigenetic information is being inherited.” The study, led by WEHI in collaboration with Associate Professor Edwina McGlinn from Monash University and The Australian Regenerative Medicine Institute, was recently published in the journal Nature Communications. Natalia Benetti (left) and Professor Marnie Blewitt (right). Credit: WEHI Hox Genes and SMCHD1 in Embryonic Development The current research concentrated on the Hox genes, which are essential for normal skeletal development, and the protein SMCHD1, an epigenetic regulator discovered by Professor Blewitt in 2008. During embryonic development in mammals, Hox genes determine the identity of each vertebra, while the epigenetic regulator prevents these genes from being activated too early. According to the findings of this study, the quantity of SMCHD1 in the mother’s egg impacts the activity of the Hox genes and the patterning of the embryo. Without maternal SMCHD1 in the egg, children were born with altered skeletal structures. This is clear proof, according to the first author and Ph.D. researcher Natalia Benetti, that epigenetic information rather than only blueprint genetic information was passed from the mother. SMCHD1 produced by the mother (green) seen remaining in embryos as the cells divide. Researchers have found the effect of SMCHD1 from the mother impacts when Hox genes are activated many days later in development. Credit: Wanigasuriya et al. eLife 2020 “While we have more than 20,000 genes in our genome, only that rare subset of about 150 imprinted genes and very few others have been shown to carry epigenetic information from one generation to another,” Benetti said. “Knowing this is also happening to a set of essential genes that have been evolutionarily conserved from flies through to humans is fascinating.” The research showed that SMCHD1 in the egg, which only persists for two days after conception, has a life-long impact. Potential Applications for Treating Genetic Disorders Variants in SMCHD1 are linked to the developmental disorder Bosma arhinia microphthalmia syndrome (BAMS) and facioscapulohumeral muscular dystrophy (FSHD), a form of muscular dystrophy. The researchers say their findings could have implications for women with SMCHD1 variants and their children in the future. A drug discovery effort at WEHI is currently leveraging the SMCHD1 knowledge established by the team to design novel therapies to treat developmental disorders, such as Prader Willi Syndrome and the degenerative disorder FSHD. Reference: “Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo” by Natalia Benetti, Quentin Gouil, Andres Tapia del Fierro, Tamara Beck, Kelsey Breslin, Andrew Keniry, Edwina McGlinn and Marnie E. Blewitt, 25 July 2022, Nature Communications. DOI: 10.1038/s41467-022-32057-x The study was funded by the NHMRC, a Bellberry-Viertel Senior Medical Research fellowship, the Victorian Government, and the Australian Government.

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