Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Customized sports insole ODM Indonesia

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Taiwan flexible graphene product manufacturing

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.China custom insole OEM supplier

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Indonesia custom neck pillow ODM

A study has revealed that fungi can exhibit intelligent behaviors like decision-making and learning, without having a brain. Credit: ©Yu Fukasawa et al. Researchers have discovered that fungi, despite lacking brains, exhibit forms of intelligence such as memory, learning, and decision-making. Through experiments, fungi demonstrated strategic growth patterns when exposed to different physical setups, suggesting a form of communication within their mycelial networks. This groundbreaking study reveals the complex and intelligent behaviors of fungi, challenging our understanding of cognition in simple organisms. Exploring Fungal Intelligence Can organisms without a brain still show signs of intelligence? Researchers at Tohoku University and Nagaoka College had this question in mind when conducting a study to measure the decision-making processes in fungi. While it may sound like science fiction, this level of basal cognition is possible even in fungi. “You’d be surprised at just how much fungi are capable of,” remarks Yu Fukasawa of Tohoku University, “They have memories, they learn, and they can make decisions. Quite frankly, the differences in how they solve problems compared to humans is mind-blowing.” Fungal mycelial networks connecting wood blocks arranged in circle (left) and cross (right) shapes. Credit: ©Yu Fukasawa et al. The Underground Network Fungi grow by releasing spores, which can germinate and form long, spidery threads underground (a mycelium). We typically only see the tiny mushrooms on the surface without realizing that there’s a vast network of interconnected mycelium beneath our feet. It is through this network that information can be shared, somewhat like neural connections in the brain. Fungal Decision-Making Observed The present study examined how a wood-decaying mycelial network responded to two different situations: wood blocks placed in a circle versus cross arrangement. For example, if the fungi didn’t display decision-making skills, they would simply spread out from a central point without consideration for the position of the blocks. Remarkably, this is not what the researchers witnessed. For the cross arrangement, the degree of connection was greater in the outermost four blocks. It was hypothesized that this was because the outermost blocks can serve as “outposts” for the mycelial network to embark in foraging expeditions, therefore more dense connections were required. In the circle arrangement, the degree of connection was the same at any given block. However, the dead center of the circle remained clear. It was proposed that the mycelial network did not see a benefit in overextending itself in an already well-populated area. Implications for Understanding Fungal Ecology These findings suggest that the mycelial network was able to communicate information about its surroundings throughout the entire network, and change its direction of growth accordingly based on the shape. Our comprehension of the mysterious world of fungi is limited, especially when compared to our knowledge of plants and animals. This research will help us better understand how biotic ecosystems function and how different types of cognition evolved in organisms. These results were published in the journal Fungal Ecology. Reference: “Spatial resource arrangement influences both network structures and activity of fungal mycelia: A form of pattern recognition?” by Yu Fukasawa, Kosuke Hamano, Koji Kaga, Daisuke Akai and Takayuki Takehi, 12 September 2024, Fungal Ecology. DOI: 10.1016/j.funeco.2024.101387

Tiger Sharks New research indicates that baited shark diving can influence tiger shark social behavior. Scientists at the University of Miami Rosenstiel School of Marine and Atmospheric Science (UM) and the Institute of Zoology at the Zoological Society London (ZSL) found that tiger sharks, often considered a solitary nomadic species, are social creatures, having preferences for one another.  A first of its kind, the study also evaluated if exposure of the tiger shark to baited dive tourism impacted their social behavior. The study was conducted at a site named Tiger Beach, located off the north-west side of Little Bahama bank in the Bahamas. The area is known for hosting shark diving encounters, where the sharks are attracted with chum and often fed in front of dive tourists. Baited shark dives are often conducted by dive tourism companies to attract the animals so that tourists may observe them. This approach has been known to cause mixed feelings among conservationists and shark experts, due to the possible long-term impacts on the predators, such as changes to their natural foraging behavior. This study found that tiger sharks aggregated at the dive sites, but social preferences between sharks were less prevalent as compared to areas outside of these dive sites. These results suggest that feeding sharks may disrupt their social organization, but only temporarily, as the study found that tiger sharks resumed their social groupings outside of the dive sites. Credit: University of Miami Rosenstiel School of Marine and Atmospheric Science The research team tagged and tracked the movements of tiger sharks over the course of three years. They then applied a tool called Social Network Analysis to the tracking data to examine if tiger sharks exhibited social grouping behavior and if this social behavior differed at locations where sharks were exposed to baited shark dive tourism. The study not only found that tiger sharks formed social groups, but also discovered that at sites where tiger sharks were being fed by dive tourism operators, tiger sharks became more aggregated, but interactions between sharks became more random, suggesting a breakdown in social organization. “Given that tiger sharks spend months at a time out in the open ocean as solitary predators, it’s amazing to me that they show social preferences for one another when they are at the Tiger Beach area,” said Neil Hammerschlag, senior author of the study and research associate professor at the UM Rosenstiel School. “For nearly two decades, I have spent countless hours diving at Tiger Beach, always wondering if these apex predators interacted socially. Now we know.” Tiger sharks form social groups at sites where they are fed by dive tourism operators. Credit: Neil Hammerschlag, Ph.D., University of Miami Rosenstiel School of Marine and Atmospheric Science Baited shark dives are often conducted by dive tourism companies to attract the animals so that tourists may observe them. This approach has been known to cause mixed feelings among conservationists and shark experts, due to the possible long-term impacts on the predators, such as changes to their natural foraging behavior. This study found that tiger sharks aggregated at the dive sites, but social preferences between sharks were less prevalent as compared to areas outside of these dive sites. These results suggest that feeding sharks may disrupt their social organization, but only temporarily, as the study found that tiger sharks resumed their social groupings outside of the dive sites. “The boundary between wildlife and people is becoming increasingly thin, so as well as observing a new social behavior for the first time in what was once thought of as a solitary shark, we also measured the impacts of human activity on these predators’ interactions.  They seem to show some resilience to the bait feeding,” said David Jacoby, ZSL Honorary Research Associate and lead author of the study. The social behavior of predators is an important area of study as it provides another tool to help scientists and wildlife managers build a picture of how they live, what drives them to form social groups, and the roles they play within the wider ecosystem.  Reference: “Social Network Analysis Reveals the Subtle Impacts of Tourist Provisioning on the Social Behavior of a Generalist Marine Apex Predator” by David M. P. Jacoby, Bethany S. Fairbairn, Bryan S. Frazier, Austin J. Gallagher, Michael R. Heithaus, Steven J. Cooke and Neil Hammerschlag, 3 September 2021, Journal Frontiers in Marine Science. DOI: 10.3389/fmars.2021.665726 The study was published on September 3 in the Journal Frontiers in Marine Science, authors include David M. Jacoby, Institute of Zoology, Zoological Society of London, United Kingdom, Bethany S. Fairbairn, University College of London, United Kingdom, Bryan Frazier, Marine Resources Research Institute, South Carolina Department of Natural Resources, Austin J. Gallagher, Beneath the Waves, Michael R. Heithaus, Institute of Environment, Department of Biological Science, Florida International University, Steven J. Cooke, Fish Ecology and Conservation Physiology Laboratory, Carleton University, Canada, and Neil Hammerschlag, University of Miami Rosenstiel School of Marine and Atmospheric Science, and Leonard and Jayne Abess Center for Ecosystem Science and Policy, University of Miami. About the University of Miami’s Rosenstiel School The University of Miami is one of the largest private research institutions in the southeastern United States. The University’s mission is to provide quality education, attract and retain outstanding students, support the faculty and their research, and build an endowment for University initiatives. Founded in the 1940’s, the Rosenstiel School of Marine & Atmospheric Science has grown into one of the world’s premier marine and atmospheric research institutions. Offering dynamic interdisciplinary academics, the Rosenstiel School is dedicated to helping communities to better understand the planet, participating in the establishment of environmental policies, and aiding in the improvement of society and quality of life.

The Atlantic longfin inshore squid, Doryteuthis pealeii, has been studied for nearly a century by scientists as a model system for neuroscience investigations. Credit: Elaine Bearer Cephalopod genomes underwent massive rearrangements and contain novel gene families, helping explain their evolution. These changes are linked to the development of large, complex nervous systems. Squid, octopus, and cuttlefish – even to scientists who study them – are wonderfully weird creatures. Known as the soft-bodied or coleoid cephalopods, they have the largest nervous system of any invertebrate, complex behaviors such as instantaneous camouflage, arms studded with dexterous suckers, and other evolutionarily unique traits. Now, scientists have dug into the cephalopod genome to understand how these unusual animals came to be. Along the way, they discovered cephalopod genomes are as weird as the animals are. Scientists from the Marine Biological Laboratory (MBL) in Woods Hole, the University of Vienna, the University of Chicago, the Okinawa Institute of Science and Technology and the University of California, Berkeley, reported their findings in two new studies published in the journal Nature Communications. “Large and elaborate brains have evolved a couple of times,” said co-lead author Caroline Albertin, Hibbitt Fellow at the MBL. “One famous example is the vertebrates. Another is the soft-bodied cephalopods, which serve as a separate example for how a large and complicated nervous system can be put together. By understanding the cephalopod genome, we can gain insight into the genes that are important in setting up the nervous system, as well as into neuronal function.” California two-spot octopuses (Octopus bimaculoides) emerging from their egg casings. Credit: Caroline Albertin, Marine Biological Laboratory In Albertin et al., published this week, the team analyzed and compared the genomes of three cephalopod species – two squids (Doryteuthis pealeii and Euprymna scolopes) and an octopus (Octopus bimaculoides). Sequencing these three cephalopod genomes, never mind comparing them, was a tour de force effort funded by the Grass Foundation that took place over several years in labs around the world. “Probably the greatest advance in this new work is providing chromosomal-level assemblies of no less than three cephalopod genomes, all of which are available for study at the MBL,” said co-author Clifton Ragsdale, professor of Neurobiology and of Biology and Anatomy at the University of Chicago. “Chromosomal-level assemblies allowed us to better refine what genes are there and what their order is, because the genome is less fragmented,” Albertin said. “So now we can start to study the regulatory elements that may be driving expression of these genes.” In the end, comparing the genomes led the scientists to conclude that evolution of novel traits in soft-bodied cephalopods is mediated, in part, by three factors: massive reorganization of the cephalopod genome early in evolution expansion of particular gene families large-scale editing of messenger RNA molecules, especially in nervous system tissues. Most strikingly, they found the cephalopod genome “is incredibly churned up,” Albertin said. In a related study (Schmidbaur et al.), published last week, the team explored how the highly reorganized genome in Euprymna scolopes affects gene expression. The team found that the genome rearrangements resulted in new interactions that may be involved in making many of the novel cephalopod tissues, including their large, elaborate nervous systems. “In many animals, gene order within the genome has been preserved over evolutionary time,” Albertin said. “But in cephalopods, the genome has gone through bursts of restructuring. This presents an interesting situation: genes are put into new locations in the genome, with new regulatory elements driving the genes’ expression. That might create opportunities for novel traits to evolve.” What’s so Striking about Cephalopod Genomes? Key insights into cephalopod genomes that the studies provide include: They’re large. The Doryteuthis genome is 1.5 times larger than the human genome, and the octopus genome is 90% the size of a human’s. They’re scrambled. “Key events in vertebrate evolution, leading to humans, include two rounds of whole-genome duplication,” Ragsdale said. “With this new work, we now know that the evolution of soft-bodied cephalopods involved similarly massive genome changes, but the changes are not whole-genome duplications but rather immense genome rearrangements, as if the ancestral genomes were put in a blender.” “With this new information, we can begin to ask how large-scale genome changes might underlie those key unique features that cephalopods and vertebrates share, specifically their capacity for large bodies with disproportionately large brains,” Ragsdale said. Surprisingly, they found the three cephalopod genomes are highly rearranged relative to each other – as well as compared to other animals. “Octopus and squid diverged from each other around 300 million years ago, so it makes sense that they seem they have very separate evolutionary histories,” Albertin said. “This exciting result suggests that the dramatic rearrangements in cephalopod genomes have produced new gene orders that were important in squid and octopus evolution.” They contain novel gene families. The team identified hundreds of genes in novel gene families that are unique to cephalopods. While some ancient gene orders common to other animals are preserved in these new cephalopod gene families, the regulation of the genes appears to be very different. Some of these cephalopod-specific gene families are highly expressed in unique cephalopod features, including in the squid brain. Certain gene families are unusually expanded. “An exciting example of that is the protocadherin genes,” Albertin said. “Cephalopods and vertebrates independently have duplicated their protocadherins, unlike flies and nematodes, which lost this gene family over time. This duplication has resulted in a rich molecular framework that perhaps is involved in the independent evolution of large and complex nervous systems in vertebrates and cephalopods.” They also found species-specific gene family expansions, such as the genes involved in making the squid’s beak or suckers. “Neither of these gene families were found in the octopus. So, these separate groups of animals are coming up with novel gene families to accomplish their novel biology,” Albertin said. RNA Editing: Another Arrow in the Quiver to Generate Novelty Prior research at the MBL has shown that squid and octopus display an extraordinarily high rate of RNA editing, which diversifies the kinds of proteins that the animals can produce. To follow up on that finding, Albertin et al. sequenced RNA from 26 different tissues in Doryteuthis and looked RNA editing rates across the different tissues. “We found a very strong signal for RNA editing that changes the sequence of a protein to be restricted to the nervous system, particularly in the brain and in the giant fiber lobe,” Albertin said. “This catalog of editing across different tissues provides a resource to ask follow-up questions about the effects of the editing. For example, is RNA editing occurring to help the animal adapt to changes in temperature or other environmental factors? Along with the genome sequences, having a catalog of RNA editing sites and rates will greatly facilitate future work.” Sidebar: Why did These Cephalopods Make the Cut? These three cephalopod species were chosen for study given their past and future importance to scientific research. “We can learn a lot about an animal by sequencing its genome, and the genome provides an important toolkit for any sort of investigations going forward,” Albertin said. They are: The Atlantic longfin inshore squid (Doryteuthis pealeii). Nearly a century of research on this squid at the MBL and elsewhere has revealed fundamental principles of neurotransmission (some discoveries garnering a Nobel Prize). Yet this is the first report of the genome sequence of this well-studied squid (in Albertin et al., funded by the Grass Foundation). Two years ago, an MBL team achieved the first gene knockout in a cephalopod using Doryteuthis pealeii, taking advantage of preliminary genomic sequence data and CRISPr-Cas9 genome editing. The Hawaiian bobtail squid (Euprymna scolopes). A glowing bacterium lives inside a unique “light organ” in the squid, to the mutual benefit of both. This species has become a model system for studying animal-bacterial symbiosis and other aspects of development. A draft E. scolopes genome assembly was published in 2019. The California two-spot octopus (Octopus bimaculoides). A relative newcomer on the block of scientific research, this was the first octopus genome ever sequenced. Albertin co-led the team that published its draft genome in 2015. References: “Genome and Transcriptome Mechanisms Driving Cephalopod Evolution” by Caroline B. Albertin, Sofia Medina-Ruiz, Therese Mitros, Hannah Schmidbaur, Gustavo Sanchez, Z. Yan Wang, Jane Grimwood, Joshua J. C. Rosenthal, Clifton W. Ragsdale, Oleg Simakov and Daniel S. Rokhsar, 4 May 2022, Nature Communications. DOI: 10.1038/s41467-022-29748-w Co-authors are from the Marine Biological Laboratory (Caroline Albertin and Joshua Rosenthal), University of California-Berkeley, University of Vienna, Hiroshima University, University of Chicago, Hudson Alpha Institute of Biotechnology, Okinawa Institute for Science and Technology, and Chan-Zuckerberg Biohub. “Emergence of novel cephalopod gene regulation and expression through large-scale genome reorganization” by Hannah Schmidbaur, Akane Kawaguchi, Tereza Clarence, Xiao Fu, Oi Pui Hoang, Bob Zimmermann, Elena A. Ritschard, Anton Weissenbacher, Jamie S. Foster, Spencer V. Nyholm, Paul A. Bates, Caroline B. Albertin, Elly Tanaka and Oleg Simakov, 21 April 2022, Nature Communications. DOI: 10.1038/s41467-022-29694-7 Co-authors are from University of Vienna; Institute of Molecular Pathology, Vienna; The Frances Crick Institute; The Vienna Zoo; University of Florida; Marine Biological Laboratory; and University of Connecticut.

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