01.Raynaud phenomenon
02.Arthralgia/arthritis
03.Esophageal hypomotility
04.Pulmonary dysfunction
05.Swollen hands
06.Myositis
07.Rash
08.Leukopenia
09.Sclerodactyly
10.Pleuritis/pericarditis
11.Pulmonary hypertension
12.high level of anti–U1-RNP antibodies
13.antibodies against U1-70 kd small nuclear ribonucleoprotein (snRNP)