PT

PTT

Possible Condition Present

Prolonged

Normal

Liver disease

decreased vitamin K

decreased or defective factor VII

Normal

Prolonged

Decreased or defective factor VIII, IX or XI

or lupus anticoagulant present

Prolonged

Prolonged

Decreased or defective factor I, II, V or X,

von Willebrand disease,

liver disease,

DIC

Normal

Normal

Decreased platelet function,

thrombocytopenia,

factor XIII deficiency,

mild deficiencies in other factors,

mild form of von Willebrand’s disease