What Is Spice/K2 Made Of?

Natural marijuana gains its mind-altering effects from a chemical known as THC.

Synthetic marijuana, on the other hand, is coated with synthetic cannabinoids – a family of over 700 research chemicals.

In other words, synthetic marijuana / K2 / Spice is completely different than natural marijuana.

「K2(Spice)」及-氯安非他命列為第三級管制藥品

• 為遏止俗稱K2或 Spice及對-氯安非他命等新興濫用物質濫用，行政院於100年10月20日公告增列「K2(Spice)」內常見所含之5種類大麻活性物質(CP47,497、JWH-018、JWH-073、JWH-250、HU-210)及對-氯安非他命為第三級管制藥品。
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  我國分別自去(99)年及前(98)年起陸續發現K2及對-氯安非他命之濫用情形，且驗出件數逐漸增加，顯示濫用情形已日趨嚴重，K2所含之類大麻活性物質及對-氯安非他命業於100年4月26日及100年 6月20日經行政院公告列為第三級毒品加強管制。
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   類大麻活性物質及對-氯安非他命無醫療用途，惟機構業者如欲使用前述管制藥品進行醫藥教育研究試驗，須領有管制藥品登記證，且使用管制藥品之醫藥教育研究試驗計畫，須向行政院衛生署申請核准後，始得使用。倘非法使用，則依違反毒品危害防制條例論處。
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  K2外觀狀似菸草或花草茶，由乾燥之植物碎片組成，且混合多種類大麻活性物質(包括CP47,497、JWH-018、JWH-073、JWH-250、HU-210等)，其多以煙吸方式施用，施用後有類似大麻的迷幻作用，還有如嘔吐、妄想、精神恍惚、情緒激動、心跳加速、失憶等現象，甚者，可能導致中毒、死亡，另其以吸食方式施用會影響呼吸系統。
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  對-氯安非他命俗稱PCA或4CA，為安非他命衍生物，常以搖頭丸名義被販賣，施用後產生類似安非他命之中樞神經興奮效果，且其毒性較安非他命強，長期施用易造成記憶損傷、高血壓、心跳加速、體溫升高甚至致死，其致死劑量與致效劑量相差極小，具高危險性。
  衛生署食品藥物管理局再度呼籲民眾，千萬不要因為一時的好奇或同儕的影響而輕易嚐毒，毒品變裝千奇百怪，推陳出新，年輕族群或經常出入娛樂場所之民眾，更要提高警覺，注意自身的安全，拒絕來路不明的藥物、咖啡包、茶包或試喝包，避免掉入新興毒品之陷阱，以免花錢傷身又受罰。

What Is Spice / K2?

Spice / K2: It’s Not What You Think!

Many people have heard about Spice or K2, also known as synthetic cannabis, fake pot, synthetic marijuana, legal weed, herbal incense and potpourri.

But most people have no idea how this awful synthetic drug is affecting millions of people all over the world.

The word is leaking out, however, as reports to Poison Control and emergency room visits have skyrocketed over the past few years.

This page answers the question: what exactly is Spice / K2 – and what does it do to you?

What Does Spice Look Like?

Traditional smoked Spice/K2 looks like herbal tobacco, or natural marijuana.

It’s actually made from dried plant material and chopped up herbs in a mixture of colors including beige, cream red and brown.

The active ingredients are synthetic chemicals (cannabinoids) sprayed onto the plant material.

At first, people believed Spice was simply a mixture of harmless herbs that had a similar effect to marijuana, so it was legally sold all over the world, especially via the internet. It was attractively packaged in small colorful sachets, and generally marketed as a herbal smoking tobacco substitute, or as incense. The packaging had a kind of 60’s, summer of love, retro feel, which gave it an aura of harmlessness.

Synthetic cannabinoids are a class of molecules that bind to cannabinoid receptors in the body—the same receptors to which THC and CBD attach–which are cannabinoids in cannabis plants. Synthetic cannabinoids are also designer drugs that are often sprayed onto plant matter.^[1] They are typically consumed through smoking,^[2] although more recently they have been consumed in a concentrated liquid form in the US and UK.^[3] They have been marketed as herbal incense, or “herbal smoking blends”^[2] and sold under common names like K2, Spice,^[4] and Synthetic Marijuana.^[1] They are also often labeled “not for human consumption.”^[4]

 合成大麻合成大麻於2004年首次出現在歐洲，2008年在美國，被以「香料」之名出售。 用來製造合成大麻的化學藥物，數十年前是被創造來做實驗用的， 它們包括：

• 「CP47,497」是以輝瑞製藥廠的查理斯．輝瑞為名，是1980年代開發來做科學實驗用的。
• 「HU-210」是以耶路撒冷的希伯來大學為名，於1988年首度開發出來。 其效力比天然的THC（大麻中改變心智狀態的成分）還強一百至八百倍。
• JWH-018跟JWH系列的其他藥物都以南加州克里門森大學的約翰．W．霍夫曼教授為名，是在1995年創造出來的。

2010年間，美國藥品執行管理局動用緊急處理權來管控這些化學藥物，禁止合成大麻成分的法令也在2012年通過。

地下化學藥物專家就發展新的類似大麻效用的實驗性藥物UR-144以及XLR11，用來取代被禁的藥物。 2013年間，UR-144以及XLR11變成非法藥物，但同時新一代合成大麻出現了。 重點不在這些藥物是否合法， 研究顯示這些藥物有毒而且不安全。

到目前為止，合成大麻已出現一百多種不同版本。 因為化學成分不斷改變，買方無從得知對身體會產生什麼樣的影響。