數學系可是個大系，因為它的應用及未來出路其實是非常廣的，基本上它可細分為好幾大類專業，例如幾何、代數、應用數學、分析、統計、邏輯或topology等，故各大類的學校排名事實上是有許多的差異，但下列的排名並沒有依照它的分類來排列，而是依照其數學的總體學術專業表現來排名，資料來源是2009年US World News:

1 Princeton University Princeton, NJ
2 Harvard University Cambridge, MA
2 Massachusetts Institute of Technology Cambridge, MA
2 Stanford University Stanford, CA
2 U of California–Berkeley Berkeley, CA
6 U of Chicago Chicago, IL
7 California Institute of Technology Pasadena, CA
7 Yale University New Haven, CT
9 Columbia University New York, NY
9 New York University New York, NY Distance
9 U of Michigan–Ann Arbor Ann Arbor, MI
12 U of California–Los Angeles Los Angeles, CA
13 Cornell University Ithaca, NY
14 Brown University Providence, RI
14 U of Texas–Austin Austin, TX
14 U of Wisconsin–Madison Madison, WI
17 U of Minnesota–Twin Cities Minneapolis, MN
18 Northwestern University Evanston, IL
18 U of Illinois–Urbana-Champaign Urbana, IL
18 U of Pennsylvania Philadelphia, PA
21 Duke University Durham, NC
21 Johns Hopkins University Baltimore, MD
21 University of Maryland–College Park College Park, MD
24 Rutgers, the State University of New Jersey–New Brunswick Piscataway, NJ
24 SUNY–Stony Brook Stony Brook, NY
24 U of California–San Diego La Jolla, CA
24 U of Washington Seattle, WA
28 Indiana University–Bloomington Bloomington, IN
28 Pennsylvania State University–University Park University Park, PA
28 Purdue University–West Lafayette West Lafayette, IN
28 Rice University Houston, TX
28 U of North Carolina–Chapel Hill Chapel Hill, NC
33 Carnegie Mellon Uni Pittsburgh, PA
33 Ohio State Uni Columbus, OH
33 U of Utah Salt Lake City, UT
36 CUNY Graduate School and Uni Center New York, NY
36 Georgia Institute of Technology Atlanta, GA
36 U of California–Davis Davis, CA
36 U of Illinois–Chicago Chicago, IL
40 Brandeis Univ Waltham, MA
40 U of Arizona Tucson, AZ
40 U of Virginia Charlottesville, VA
40 Washington Univ in St. Louis St. Louis, MO
44 Michigan State Univ East Lansing, MI
44 Texas A&M Univ–College Station College Station, TX
44 U of California–Irvine Irvine, CA
44 U of Notre Dame Notre Dame, IN
48 Boston Univ Boston, MA
48 Dartmouth College Hanover, NH
48 North Carolina State Univ Raleigh, NC
48 U of California–Santa Barbara Santa Barbara, CA
48 U of Colorado–Boulder Boulder, CO
48 Vanderbilt Univ Nashville, TN
48 Virginia Tech Blacksburg, VA
55 U of Georgia Athens, GA
55 U of Iowa Iowa City, IA
55 U of Southern California Los Angeles, CA
58 Northeastern Uni Boston, MA
58 Rensselaer Polytechnic Institute Troy, NY
58 U of Florida Gainesville, FL
58 U of Missouri–Columbia Columbia, MO
58 U of Oregon Eugene, OR
58 U of Pittsburgh Pittsburgh, PA
64 Arizona State Uni Tempe, AZ
64 Claremont Graduate Uni Claremont, CA
64 Iowa State Uni Ames, IA
64 Louisiana State Uni–Baton Rouge Baton Rouge, LA
64 U of Kansas Lawrence, KS
64 U of Massachusetts–Amherst Amherst, MA
70 Florida State Uni Tallahassee, FL
70 U of California–Riverside Riverside, CA
70 U of Delaware Newark, DE
70 U of Rochester Rochester, NY
70 U of Tennessee–Knoxville Knoxville, TN