必利勁（Priligy）（化學名:鹽酸達泊西汀），是目前唯一針對早洩（PE）研發的藥物，也是唯一獲得台灣衛生署批準的早洩（PE）這應症的治療藥物。服用必利勁後沒有臉紅心跳加速等癥狀、無副作用、見效時間快、能有效解決陽痿早洩症狀，提升性能力，首次服用必利勁即可起效，在性生活開始前1-2小時服用即可，能夠在體內迅速吸收且消除副反應發生的特性使得必利勁是用於治療早洩（PE）的最理想壯陽藥。

必利勁：https://www.poxate.tw/

男人，關鍵時刻不舉怎麼辦？治療早洩醫師推薦服用必利勁。有效治療早洩。達泊西汀學名藥：必利勁（POXET-60）

必利勁使用方法及吃法：

口服，一定要整片吞下，不要在口中停留時間太長。建議礦泉水壹瓶水送服10分鐘內喝完，前三次服用會有頭暈，或者輕微頭痛的情況，不過不要有擔心，這種情況都是正常的。對於首次服用的朋友，第壹次推薦30mg服用，如果30mg 效果不夠理想可以增加至60mg，最大劑量是24小時60mg。必利勁可以在餐前兩小時或餐後兩小時服用。避免吃過多油膩和酸性食物，以免影響效果。

老年人（65歲及以上）：

尚未評估必利勁在65歲及以上患者人群中使用的安全性和療效，其主要原因為有關本產品在該人群中使用的數據極為有限（慘見藥代動力學部分）。

兒童及青少年：必利勁不用於18歲以下人群。

腎臟損傷患者：輕度或中度腎臟損傷患者服用必利勁時不需要進行劑量調整，但是應謹慎服用。不推薦必利勁用於重度腎臟損傷患者（慘見藥代動力學部分）。

肝損傷患者：輕度肝損傷患者服用必利勁時不需要進行劑量調整。

【醫師推薦訂購】：重度早洩患者（2年以上早洩症狀，愛愛時間隻有2-3分鐘） ：100顆 

                          中度早洩患者（1-2年早洩症狀，愛愛時間隻有3-5分鐘）     ：60顆

                         輕度早洩患者（1年以下早洩症狀，愛愛時間隻有5-10分鐘）：30顆

必利勁;https://www.poxate.tw/

【產品規格】：60mg/1顆  1盒10顆

【功效】：治療早洩 射精無力 勃起不正常患者

【保質期】：36個月

【禁忌】：心臟病患者等疾病不可服用（服用必利勁請避免飲酒）

【生產廠家】： sunrise藥廠 （印度三大藥廠之一）

必利勁特殊人群用藥：

【孕婦及哺乳期婦女用藥】：婦女不適合使用本品。

【兒童用藥】：本品不應用於18歲以下人群。

【老年用藥】：尚未評估本品在65歲及以上患者人群中使用的安全性和療效，其主要原因為本產品在該人群中使用的數據極為有限。

對使用60mg鹽酸達泊西汀的單次給藥臨床藥理學研究的分析表明，健康老年男性與健康青年男性在藥代動力學參數（Cmax，AUCinf，Tmax）上沒有顯著差異。

醫學專家解讀必利勁（poxet-60）：

必利勁（英文名：Priligy 化學名：必利勁）是目前唯一針對早洩（PE）研發的藥物，也是唯一獲得國家食品藥品監督管理局（CEDA）批準的早洩（PE）這應癥的治療藥物，必利勁是全球公認的治療早洩最有效的藥物，延時效果超級好，俗稱早洩剋星，它是治療性的藥物，不是所謂激素性的藥物，也沒有依賴性。隨著服用次數的增加，纍計服用壹定數量時（每個人體質不同，數量不同），即使停用藥物性生活時間也可維持在服藥時的水平。必利勁讓早洩男同胞看到了希望喔。必利勁延時效果強勁，副作用小。三倍延時，有效延長性愛時間20分鐘以上，讓您肆意享受。溫馨提示：空腹效果最佳。

必利勁：https://www.poxate.tw/

一、印度版必利勁（POXET-60）與美國販售的版本區別？

成分上是沒有任何區別的，印度被稱為世界‘藥都’。印度法律保護當地藥廠進行強防，所以世界上的先進藥印度基本都可以找得到。而且印度的藥品價格相當於原研藥的十分之壹，甚至百分之壹！還有各種治療癌癥的藥物。印度的製藥技術也先進於大六20年這是不爭的事實，同時印度的壹些藥廠在國際上也是很知名的！這就是為什麼印度藥會那麼受全球國家歡迎。在效果和原廠藥相同，價格要優惠很多。

印度版學名藥叫：必利勁（POXET-60）https://www.poxate.tw/

學名藥瞭解：學名藥是指原廠藥的專利過期後，其他藥廠可以以同洋成份與製程生產已核準之藥品，其在用途、劑型、安全性、效力、給藥途徑、品質、藥飰等各項特性上，皆可以與原廠藥完全相同或具有生物相等性。 學名藥產業即為生產製造及銷售與原廠藥同成份、同劑量、同療效之製劑，且需待原廠藥專利過期後，學名藥廠才能將產品上市。

結論顯示，必利勁对90%的人产生效果，經過適應，射精潛伏時間可延長3-4倍。

必利勁能夠有效改善男性早洩症狀，必利勁官網銷售產品保證原廠進口，支持無效退費。

Sponsored by Leqvio (inclisiran).

Please note Bruce Arians is not a Leqvio patient. Continue reading for safety information.

Managing heart health is a team effort — even for legendary football coach Bruce Arians. In 2017, he experienced chest pains that landed him in the hospital. He learned that he has atherosclerotic cardiovascular disease (ASCVD — also referred to as “known heart disease”), which is the most common type of heart disease. It is caused by consistent high levels of LDL-C, or bad cholesterol, in the blood, which can lead to a buildup of plaque on the walls of arteries within the heart.¹

For Arians, whose father died of a heart attack, the trip to the hospital and the subsequent diagnosis was the wake-up call that he needed to prioritize and stay on top of his heart health, no matter how busy his schedule became.

Arians took steps to make sure he was effectively managing his high levels of bad cholesterol. This included lifestyle modifications, like changes to his diet and becoming more active, as well as taking medications. “Coaches have a tendency to be a superman,” Arians says. “I had to give up on that, and say, ‘No, I’m not. I need help.’”

While it’s critical that people struggling with high levels of bad cholesterol manage their condition, they don’t have to do it alone. A team mentality can be key in achieving a healthy heart. In addition to a doctor, patients also can consider who else makes sense on their bench. For some, this might be learning some winning plays from a physical therapist or dietician.

Others find that their spouse is an effective quarterback calling the diet and movement plays that lead them to success. And of course, fans in the stands are critical. These fans include friends and family members who cheer on small victories and provide valuable support. Here’s what to know as you build your own heart health team — you can also visit CoachingCholesterol.com to learn more about how to make the right play for your heart health.

A multi-factor health challenge

What makes high cholesterol challenging is that often bad cholesterol does not initially cause symptoms. Rather, it builds up over years, forming plaque in the arteries and leading to outcomes that include stroke and heart disease.¹ But because bad cholesterol can be asymptomatic, many patients do not know their cholesterol numbers until they are diagnosed with heart disease.

Knowing your cholesterol numbers and acting to reduce them can help eliminate problems before they start. In sports terms, lowering bad cholesterol can be the equivalent of being ahead 35 to 0 in the fourth quarter, not giving heart disease a chance, explains Dr. Jeffrey Boone, president, CEO and medical director of the Boone Heart Institute. “The goal of treating LDL cholesterol is to reduce cardiovascular events,” he says. “We can’t feel plaques as they grow. That’s why it can be important to treat high LDL-C before any chest pain or symptoms occur.”

And often, with high levels of bad cholesterol, diet and exercise alone may not be enough to lower numbers. In some cases, even medication, such as a statin, may not be sufficient.²⁻⁴ That’s why it can be critical for patients to partner with their doctor to manage their treatment and find a personalized plan that works best for them.

必利勁“The first approach is to begin to look at a patient’s lifestyle, which includes everything from stress levels to diet,” says Boone, who likens lowering cholesterol to a trapeze act — including making sure a few safety nets are in place. “I always encourage my patients, even as they're developing these lifestyle efforts, to begin developing a strong safety net, which then could begin with various medications and treatments.”

Heart health success can be built on small habits

When it comes to managing heart health, small habits make a big difference. For those taking medication, it’s often important that medication be taken at the same time each day for maximum effectiveness. Just setting an alarm and prioritizing taking medication can be the first step to implementing larger changes, like modifying your dietary habits.

For example, you might opt for a breakfast that is rich in soluble fiber, like oatmeal, which can help to lower bad cholesterol and improve overall heart health. Part of the game plan is finding foods you enjoy, coupled with accountability.

Lauren Antonucci, a registered dietician and nutritionist, says that she always begins sessions with a “proactive approach.” She has seen that many clients know what they can’t eat, but she encourages clients to dig into what they can add to their diet. This mindset shift can be helpful in building a playbook that makes sense. “We’ll talk: Do you like apples and pears? Can you add flaxseeds? It’s all about creating a toolkit of behaviors,” she says.

“I recently lost a lot of weight this past season, working with a nutritionist,” Arians says, adding that a nutritionist helped keep him accountable and ensured he was regularly eating healthy foods. “And now, when I’m on vacation or at home, I make sure I have the right ingredients.” Arians credits his nutritionist’s recommendation to make small changes in his daily routine — such as starting the day with a nutrient-dense shake and grilling at home — for making a huge improvement in his health.

Slow and steady movement is a heart health victory

Along with medication and diet, movement can be effective in lowering bad cholesterol and improving heart health. But the key to success isn’t the most reps in the gym or the fastest mile time. Instead, it’s finding healthy habits that can stick. Going on a walk after dinner every day or completing a doctor-approved strength training routine a few times a week can be small tweaks that add up.

“I tore my Achilles last year, so I can’t really do the treadmill right now,” Arians says, adding that he’s able to work out using a strength-training program that uses band exercises and weights. Working with a trainer has also given him accountability.

Femi Betiku, a doctor of physical therapy, often works with patients who are working to lower their bad cholesterol. Betiku has seen firsthand that consistency is what sets clients up for success. For some clients, that means starting at working out for 15 minutes a day. “I’ll have clients who do this for a few weeks, and then say, ‘Fifteen minutes is easy. Can I do more?’ And I say no. We’ll lead up to that, but the biggest setup for success is being able to be consistent for that initial 15 or 20 minutes.”

It’s also helpful to realize your “why.” Instead of working out solely because of your doctor’s orders, some people find it helpful to train for an event, such as walking a 5k with friends and family. Others think of the long term benefits of being active, including being able to dance at a child’s wedding or play on the floor with their grandchildren.

Despite best efforts and lifestyle changes, sometimes cholesterol management requires medication. And advances in treatment plans have led to effective ways to target bad cholesterol. For example, Leqvio, an injectable medication taken alongside diet and statins, prevents the production of PCSK9, a protein that can increase levels of bad cholesterol.⁵

While statins work by chemically reducing cholesterol production, Leqvio protects the body’s cholesterol receptors that naturally clear cholesterol from the bloodstream before plaque buildup can ever begin. These cholesterol receptors need to be protected from a protein particle called PCSK9, which neutralizes the receptors’ ability to remove bad LDL from the blood vessels. Leqvio allows the receptors to continue to eliminate excess cholesterol from the blood vessels.⁶

“It’s like these cholesterol receptors are catcher’s mitts. They catch the round particles that are filled with cholesterol and deposit them into the liver and then are pumped back into the body,” Boone says. “Too much cholesterol in the blood vessels is dangerous, but Leqvio helps get more cholesterol into the liver.”

Leqvio targets the protein that destroys these receptors. “Leqvio eliminates the destructive PCSK9 before it kills those ‘catcher’s mitt’ receptors, and it also lasts a long time,” he says, adding that the drug is injected every six months, after two initial injections, and is prescribed in addition to a statin and lifestyle modifications.⁵

“Leqvio is part of a toolbox,” Boone explains. “When you look at all the things that are involved in heart disease, the most accessible, easily treated, and impactful approach is to lower LDL cholesterol.” Partnering with your doctor and other health care team members can help you find a customized plan that makes sense for your body and your lifestyle — and can get you ready for many more winning plays in your lifetime.

必利勁____

From Novartis

LEQVIO (inclisiran) is an injectable prescription medicine used along with diet and other lipid-lowering medicines in adults who need additional lowering of "bad" cholesterol (LDL-C) and have known cardiovascular disease and/or heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes high levels of LDL-C. It is not known if LEQVIO can decrease problems related to high cholesterol, such as heart attacks or stroke. Talk to your health care provider about how Leqvio works differently than other cholesterol-lowering treatments. Click here to view LEQVIO full prescribing information.

IMPORTANT SAFETY INFORMATION

The most common side effects of LEQVIO were: injection site reaction (including pain, redness, and rash), joint pain, urinary tract infection, diarrhea, chest cold, pain in legs or arms and shortness of breath.

These are not all the possible side effects of LEQVIO. Ask your health care provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

To learn more about Coach Bruce Arians’ story and for additional resources to help update your heart health game plan, visit CoachingCholesterol.com.

This article was paid for by Novartis and created by Yahoo Creative Studios. The Yahoo Sports editorial staff did not participate in the creation of this content.

9/22 229423

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